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The map label for this gene is umuC [H]

Identifier: 29144547

GI number: 29144547

Start: 4456072

End: 4457346

Strand: Reverse

Name: umuC [H]

Synonym: t4291

Alternate gene names: 29144547

Gene position: 4457346-4456072 (Counterclockwise)

Preceding gene: 29144549

Following gene: 29144546

Centisome position: 93.02

GC content: 50.9

Gene sequence:

>1275_bases
ATGTTCGCCCTGGCTGACGTCAACAGCTTCTACGCGAGCTGTGAAAAAGTATTTCGTCCCGATTTACGTAATACACCTGT
TGTGGTGCTCAGTAACAACGATGGATGTGTTATCGCGCGTTCAAAAGAAGCGAAGCAACTGGGCATTAAAATGGGGGTTC
CGTGGTTTCAACTGAAAACAACCGAATTTCCTGTACCTGTCGTTGCGTTCTCGAGTAACTACGAACTCTACGCGTCGATG
TCGAACCGTGTTATGGCGCATCTCGAAGAACTGGCACCTCGCGTTGAGCAGTATTCTATCGACGAAATGTTTCTTGATGT
GCGCAATATTGACAGTTGTATCGATTTTGAAGACTTCGGCCGGCAGTTGCGCGAGCATGTACATTCAGGAACCGGACTGA
CCATCGGAGTTGGGATGGGACCGACCAAGACACTGGCAAAAAGCGCACAATGGGCGTCTAAGGAATGGCGGCAGTTTGAG
GGCGTGCTTGCTCTGACTTCAGGCAATCCAAAGCGAACGGAGAAACTATTGTCACTGCAGCCAGTAGACGAAATCTGGGG
GGTTGGTCGCCGGATCTCGAAGAAACTGCACACAATGGGGATAACAACTGCACTGCAGCTGGCGCGCGCGAACCCAACAT
TTATCAGGAAAAATTTCAGTGTTGTTCTCGAGAGAACTGTCCGTGAACTGAACGGGGAAAGCTGTATTTCACTGGAGGAG
GCTCCGCCACCCAAGCAGCAGATTGTCTGCAGCCGATCCTTTGGGGAGCGCGTCACAACATATGAAGCCATGCGCCAGGC
AGTCTGTCAGTATGCTGAGCGTGCAGCTGAAAAGCTGCGCGGCGAGCGGCAATTCTGCAGACATGTTGCTGTATTTGTGA
AGACGTCACCGTTCGCTGTGAACGAACCGTATTACGGGAATGTGGCCAGTGAGAAACTGACGACTCCCACGCAGGATACC
AGGGACATCATAGCCGCAGCGGTGAAAGCACTGGATCGGATCTGGGTGAAAGGGCATAGATATGCAAAAGCGGGTTGCAT
GCTCAATGATTTCACACCAACCGGGATTTCTCAGTTAAATCTTTTTGATGAAGTGCAGCCGCACGAACGAAGTGAGCAGT
TGATGAAAGTTCTCGACAGTATCAACCATTCAGGTATGGGAAAAGTGTGGTTTGCCGGAAGAGGGATAGCCCCTGAGTGG
CAGATGAAAAGAGAGCTACTCTCTCCAGCTTATACCACTCGCTGGGCTGAATTACCTGTTGCACGATTGCGCTGA

Upstream 100 bases:

>100_bases
CCGCGTCCGAAATTCCTGCATACCCTGTCCTCTATCCTGAAGAGCTGCAGATATTCGGTGTAGTGATCGCATTCGTACAC
AAAACCCGGAGTAAAGACTG

Downstream 100 bases:

>100_bases
ATCAGCTCATTGAGACTCAGTGAAAAAGGCTGAATTTCATGGTTGAAAATCAATACATTGCCATCTGAAGAACTGCTATC
GTAGTGCCAATAACCATTCT

Product: DNA polymerase V subunit UmuC

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 424; Mature: 424

Protein sequence:

>424_residues
MFALADVNSFYASCEKVFRPDLRNTPVVVLSNNDGCVIARSKEAKQLGIKMGVPWFQLKTTEFPVPVVAFSSNYELYASM
SNRVMAHLEELAPRVEQYSIDEMFLDVRNIDSCIDFEDFGRQLREHVHSGTGLTIGVGMGPTKTLAKSAQWASKEWRQFE
GVLALTSGNPKRTEKLLSLQPVDEIWGVGRRISKKLHTMGITTALQLARANPTFIRKNFSVVLERTVRELNGESCISLEE
APPPKQQIVCSRSFGERVTTYEAMRQAVCQYAERAAEKLRGERQFCRHVAVFVKTSPFAVNEPYYGNVASEKLTTPTQDT
RDIIAAAVKALDRIWVKGHRYAKAGCMLNDFTPTGISQLNLFDEVQPHERSEQLMKVLDSINHSGMGKVWFAGRGIAPEW
QMKRELLSPAYTTRWAELPVARLR

Sequences:

>Translated_424_residues
MFALADVNSFYASCEKVFRPDLRNTPVVVLSNNDGCVIARSKEAKQLGIKMGVPWFQLKTTEFPVPVVAFSSNYELYASM
SNRVMAHLEELAPRVEQYSIDEMFLDVRNIDSCIDFEDFGRQLREHVHSGTGLTIGVGMGPTKTLAKSAQWASKEWRQFE
GVLALTSGNPKRTEKLLSLQPVDEIWGVGRRISKKLHTMGITTALQLARANPTFIRKNFSVVLERTVRELNGESCISLEE
APPPKQQIVCSRSFGERVTTYEAMRQAVCQYAERAAEKLRGERQFCRHVAVFVKTSPFAVNEPYYGNVASEKLTTPTQDT
RDIIAAAVKALDRIWVKGHRYAKAGCMLNDFTPTGISQLNLFDEVQPHERSEQLMKVLDSINHSGMGKVWFAGRGIAPEW
QMKRELLSPAYTTRWAELPVARLR
>Mature_424_residues
MFALADVNSFYASCEKVFRPDLRNTPVVVLSNNDGCVIARSKEAKQLGIKMGVPWFQLKTTEFPVPVVAFSSNYELYASM
SNRVMAHLEELAPRVEQYSIDEMFLDVRNIDSCIDFEDFGRQLREHVHSGTGLTIGVGMGPTKTLAKSAQWASKEWRQFE
GVLALTSGNPKRTEKLLSLQPVDEIWGVGRRISKKLHTMGITTALQLARANPTFIRKNFSVVLERTVRELNGESCISLEE
APPPKQQIVCSRSFGERVTTYEAMRQAVCQYAERAAEKLRGERQFCRHVAVFVKTSPFAVNEPYYGNVASEKLTTPTQDT
RDIIAAAVKALDRIWVKGHRYAKAGCMLNDFTPTGISQLNLFDEVQPHERSEQLMKVLDSINHSGMGKVWFAGRGIAPEW
QMKRELLSPAYTTRWAELPVARLR

Specific function: Involved in UV protection and mutation [H]

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Escherichia coli, GI1787432, Length=420, Percent_Identity=63.0952380952381, Blast_Score=540, Evalue=1e-155,
Organism=Escherichia coli, GI1786425, Length=219, Percent_Identity=24.6575342465753, Blast_Score=69, Evalue=8e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: NA

Molecular weight: Translated: 47826; Mature: 47826

Theoretical pI: Translated: 9.02; Mature: 9.02

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFALADVNSFYASCEKVFRPDLRNTPVVVLSNNDGCVIARSKEAKQLGIKMGVPWFQLKT
CCEECHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEEECCCHHHCCCCCCCCEEEEEC
TEFPVPVVAFSSNYELYASMSNRVMAHLEELAPRVEQYSIDEMFLDVRNIDSCIDFEDFG
CCCCCEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
RQLREHVHSGTGLTIGVGMGPTKTLAKSAQWASKEWRQFEGVLALTSGNPKRTEKLLSLQ
HHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHCCC
PVDEIWGVGRRISKKLHTMGITTALQLARANPTFIRKNFSVVLERTVRELNGESCISLEE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCC
APPPKQQIVCSRSFGERVTTYEAMRQAVCQYAERAAEKLRGERQFCRHVAVFVKTSPFAV
CCCCHHHEEECHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEE
NEPYYGNVASEKLTTPTQDTRDIIAAAVKALDRIWVKGHRYAKAGCMLNDFTPTGISQLN
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEECCCCEEECCCCCCCHHHH
LFDEVQPHERSEQLMKVLDSINHSGMGKVWFAGRGIAPEWQMKRELLSPAYTTRWAELPV
HHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHCHHHHHHHHHCCH
ARLR
HHCC
>Mature Secondary Structure
MFALADVNSFYASCEKVFRPDLRNTPVVVLSNNDGCVIARSKEAKQLGIKMGVPWFQLKT
CCEECHHHHHHHHHHHHHCCCCCCCCEEEEECCCCEEEEECCCHHHCCCCCCCCEEEEEC
TEFPVPVVAFSSNYELYASMSNRVMAHLEELAPRVEQYSIDEMFLDVRNIDSCIDFEDFG
CCCCCEEEEECCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
RQLREHVHSGTGLTIGVGMGPTKTLAKSAQWASKEWRQFEGVLALTSGNPKRTEKLLSLQ
HHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCEEEEECCCHHHHHHHHCCC
PVDEIWGVGRRISKKLHTMGITTALQLARANPTFIRKNFSVVLERTVRELNGESCISLEE
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCEEECCC
APPPKQQIVCSRSFGERVTTYEAMRQAVCQYAERAAEKLRGERQFCRHVAVFVKTSPFAV
CCCCHHHEEECHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCEEE
NEPYYGNVASEKLTTPTQDTRDIIAAAVKALDRIWVKGHRYAKAGCMLNDFTPTGISQLN
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCEECCCCEEECCCCCCCHHHH
LFDEVQPHERSEQLMKVLDSINHSGMGKVWFAGRGIAPEWQMKRELLSPAYTTRWAELPV
HHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCCCHHHHHHHHHCHHHHHHHHHCCH
ARLR
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases); Serine endopeptidases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1991707 [H]