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The map label for this gene is ssb

Identifier: 29144497

GI number: 29144497

Start: 4406801

End: 4407337

Strand: Direct

Name: ssb

Synonym: t4237

Alternate gene names: 29144497

Gene position: 4406801-4407337 (Clockwise)

Preceding gene: 29144496

Following gene: 29144498

Centisome position: 91.96

GC content: 54.0

Gene sequence:

>537_bases
ATGGCTTCTAAAGGTGTAAACAAAGTTATTCTGGTGGGAAATCTGGGACAGGATCCTGAGGTGCGTTATATGCCAAATGG
CGGTGCCGTGGTAAACCTCAGTCTGGCAACCTCAGATACCTGGACAGATAAACAGACCGGTGACAAAAAAGAGCGCACTG
AATGGCACAGGGTGGTTCTTTACGGCAAGCTGGCCGAAATTGCCAGTGAGTATCTGCGTAAGGGCTCCCAGGTATACATC
GAAGGTGCATTACGCACCCGCAAATGGACGGATCAGTCTGGCGTTGAAAAGTACACTACAGAAGTGGTCGTCAGCCAGTC
AGGTACGATGCAGATGTTGGGCGGACGAAATAGTGCGGGAAGTGGGCAGCAACAGGGCGGCTGGGGTCAGCCTCAGCAAC
CAGCAGCGCCTTCTCACAGCGGGATGCCACCTCAACAGCATCCTGCAAATGAGCCGCCAATGGACTTCGACGATGATATC
CCGTTCGCGCCGTTCGGGCACAGTGTGGCCAGACATGCGCTTTATGTGCTGTCCTGA

Upstream 100 bases:

>100_bases
CCGTGAATCTGTTGAGTACTTTTCCACTCAGTCTCAGGCAGAACATGCGCTCAAACAGGGCACATGGTCACAGCGTGAAC
AGGCTTAAGGAGAGATACTC

Downstream 100 bases:

>100_bases
AAATTGTCGCTGAATAATGCCTTCCTGTGGAAGGCATTATGTTTTGAACATATGAAGGATACGGAATGGATAACGAAAAG
GGTCATAACCGGCCCGGGCA

Product: single-stranded DNA-binding protein

Products: NA

Alternate protein names: SSB 2; Helix-destabilizing protein 2

Number of amino acids: Translated: 178; Mature: 177

Protein sequence:

>178_residues
MASKGVNKVILVGNLGQDPEVRYMPNGGAVVNLSLATSDTWTDKQTGDKKERTEWHRVVLYGKLAEIASEYLRKGSQVYI
EGALRTRKWTDQSGVEKYTTEVVVSQSGTMQMLGGRNSAGSGQQQGGWGQPQQPAAPSHSGMPPQQHPANEPPMDFDDDI
PFAPFGHSVARHALYVLS

Sequences:

>Translated_178_residues
MASKGVNKVILVGNLGQDPEVRYMPNGGAVVNLSLATSDTWTDKQTGDKKERTEWHRVVLYGKLAEIASEYLRKGSQVYI
EGALRTRKWTDQSGVEKYTTEVVVSQSGTMQMLGGRNSAGSGQQQGGWGQPQQPAAPSHSGMPPQQHPANEPPMDFDDDI
PFAPFGHSVARHALYVLS
>Mature_177_residues
ASKGVNKVILVGNLGQDPEVRYMPNGGAVVNLSLATSDTWTDKQTGDKKERTEWHRVVLYGKLAEIASEYLRKGSQVYIE
GALRTRKWTDQSGVEKYTTEVVVSQSGTMQMLGGRNSAGSGQQQGGWGQPQQPAAPSHSGMPPQQHPANEPPMDFDDDIP
FAPFGHSVARHALYVLS

Specific function: This protein is essential for replication of the chromosome. It is also involved in DNA recombination and repair

COG id: COG0629

COG function: function code L; Single-stranded DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SSB domain

Homologues:

Organism=Homo sapiens, GI4507231, Length=109, Percent_Identity=31.1926605504587, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI1790494, Length=189, Percent_Identity=62.962962962963, Blast_Score=224, Evalue=2e-60,

Paralogues:

None

Copy number: 1622 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): SSB2_SALTI (Q9RHF4)

Other databases:

- EMBL:   AF000001
- EMBL:   AL627282
- EMBL:   AE014613
- RefSeq:   NP_458627.1
- RefSeq:   NP_807839.1
- ProteinModelPortal:   Q9RHF4
- SMR:   Q9RHF4
- GeneID:   1067420
- GeneID:   1250744
- GenomeReviews:   AE014613_GR
- GenomeReviews:   AL513382_GR
- KEGG:   stt:t4237
- KEGG:   sty:STY4536
- HOGENOM:   HBG755544
- OMA:   DESRTSQ
- ProtClustDB:   PRK09010
- BioCyc:   SENT209261:T4237-MONOMER
- BioCyc:   SENT220341:STY4536-MONOMER
- InterPro:   IPR012340
- InterPro:   IPR016027
- InterPro:   IPR000424
- InterPro:   IPR011344
- Gene3D:   G3DSA:2.40.50.140
- PANTHER:   PTHR10302
- TIGRFAMs:   TIGR00621

Pfam domain/function: PF00436 SSB; SSF50249 Nucleic_acid_OB

EC number: NA

Molecular weight: Translated: 19381; Mature: 19250

Theoretical pI: Translated: 7.09; Mature: 7.09

Prosite motif: PS50935 SSB

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASKGVNKVILVGNLGQDPEVRYMPNGGAVVNLSLATSDTWTDKQTGDKKERTEWHRVVL
CCCCCCCEEEEEECCCCCCCEEEECCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHEEEE
YGKLAEIASEYLRKGSQVYIEGALRTRKWTDQSGVEKYTTEVVVSQSGTMQMLGGRNSAG
HHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHEEEEEECCCCEEEECCCCCCC
SGQQQGGWGQPQQPAAPSHSGMPPQQHPANEPPMDFDDDIPFAPFGHSVARHALYVLS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHEEEECC
>Mature Secondary Structure 
ASKGVNKVILVGNLGQDPEVRYMPNGGAVVNLSLATSDTWTDKQTGDKKERTEWHRVVL
CCCCCCEEEEEECCCCCCCEEEECCCCCEEEEEEECCCCCCCCCCCCHHHHHHHHEEEE
YGKLAEIASEYLRKGSQVYIEGALRTRKWTDQSGVEKYTTEVVVSQSGTMQMLGGRNSAG
HHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCHHHHHEEEEEECCCCEEEECCCCCCC
SGQQQGGWGQPQQPAAPSHSGMPPQQHPANEPPMDFDDDIPFAPFGHSVARHALYVLS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10816445; 11677608; 12644504