Click here to switch to the map view.

The map label for this gene is pmrA [H]

Identifier: 29144461

GI number: 29144461

Start: 4363487

End: 4364155

Strand: Reverse

Name: pmrA [H]

Synonym: t4199

Alternate gene names: 29144461

Gene position: 4364155-4363487 (Counterclockwise)

Preceding gene: 29144462

Following gene: 29144460

Centisome position: 91.07

GC content: 53.96

Gene sequence:

>669_bases
ATGAAGATACTGATTGTTGAAGACGACACGCTATTATTACAGGGGTTAATACTCGCCGCGCAAACCGAAGGCTATGCGTG
TGATGGCGTTTCGACAGCGCGTGCCGCCGAGCATAGTCTGGAGTCTGGTCATTACAGTCTGATGGTGCTGGATTTAGGGC
TGCCCGATGAGGATGGCCTGCATTTCCTGACGCGAATCCGACAGAAAAAATACACCCTGCCGGTACTCATTCTGACCGCC
CGCGATACGCTCAACGACCGCATTAGCGGGCTGGATGTCGGCGCAGATGATTATCTGGTAAAACCCTTCGCCCTGGAGGA
GCTGCACGCCCGCATCCGCGCGTTGCTGCGCCGCCATAATAACCAGGGTGAAAGTGAACTGACGGTTGGCAATCTGACGC
TCAATATAGGCCGCCATCAGGCATGGAGGGATGGACAGGAACTGACCCTGACGCCTAAGGAGTACGCGCTGCTCTCACGA
TTGATGCTCAAGGCAGGCAGTCCGGTGCACCGGGAAATTCTTTATAACGATATCTACAACTGGGATAACGAACCCTCGAC
CAACACTCTGGAAGTGCATATACATAATTTGCGCGACAAAGTCGGCAAGTCGCGCATTCGCACGGTTCGCAGGTTTGGCT
ACATGCTGGTTGCCACTGAGGAAAGCTAA

Upstream 100 bases:

>100_bases
AGGACAATCTTTTCTCAACCATGCTGGGATTAACCGGCGTACAAACGACGTATTACCAGGCCGCAGATGATATTCTGCAA
CCGTGCAGGAGACTAAGCGA

Downstream 100 bases:

>100_bases
GTGAGCCTGATGCGTTTTCAGCGAAGAGCGATGACCCTTCGCCAGCGTTTAACGCTGACAATTGGTCTTATTCTGCTGGT
GTTCCAGCTAATCAGTACCT

Product: DNA-binding transcriptional regulator BasR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 222; Mature: 222

Protein sequence:

>222_residues
MKILIVEDDTLLLQGLILAAQTEGYACDGVSTARAAEHSLESGHYSLMVLDLGLPDEDGLHFLTRIRQKKYTLPVLILTA
RDTLNDRISGLDVGADDYLVKPFALEELHARIRALLRRHNNQGESELTVGNLTLNIGRHQAWRDGQELTLTPKEYALLSR
LMLKAGSPVHREILYNDIYNWDNEPSTNTLEVHIHNLRDKVGKSRIRTVRRFGYMLVATEES

Sequences:

>Translated_222_residues
MKILIVEDDTLLLQGLILAAQTEGYACDGVSTARAAEHSLESGHYSLMVLDLGLPDEDGLHFLTRIRQKKYTLPVLILTA
RDTLNDRISGLDVGADDYLVKPFALEELHARIRALLRRHNNQGESELTVGNLTLNIGRHQAWRDGQELTLTPKEYALLSR
LMLKAGSPVHREILYNDIYNWDNEPSTNTLEVHIHNLRDKVGKSRIRTVRRFGYMLVATEES
>Mature_222_residues
MKILIVEDDTLLLQGLILAAQTEGYACDGVSTARAAEHSLESGHYSLMVLDLGLPDEDGLHFLTRIRQKKYTLPVLILTA
RDTLNDRISGLDVGADDYLVKPFALEELHARIRALLRRHNNQGESELTVGNLTLNIGRHQAWRDGQELTLTPKEYALLSR
LMLKAGSPVHREILYNDIYNWDNEPSTNTLEVHIHNLRDKVGKSRIRTVRRFGYMLVATEES

Specific function: Member of the two-component regulatory system BasS/BasR. BasR induces the transcription of the ugd, ais, arnBCADTEF and eptA-basRS loci, all involved in resistance to polymyxin [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790552, Length=222, Percent_Identity=90.0900900900901, Blast_Score=411, Evalue=1e-116,
Organism=Escherichia coli, GI1789402, Length=216, Percent_Identity=45.8333333333333, Blast_Score=188, Evalue=2e-49,
Organism=Escherichia coli, GI87082012, Length=225, Percent_Identity=39.1111111111111, Blast_Score=147, Evalue=4e-37,
Organism=Escherichia coli, GI1786784, Length=221, Percent_Identity=35.7466063348416, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI1789809, Length=229, Percent_Identity=35.3711790393013, Blast_Score=130, Evalue=9e-32,
Organism=Escherichia coli, GI1787375, Length=220, Percent_Identity=32.7272727272727, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI2367329, Length=235, Percent_Identity=37.4468085106383, Blast_Score=115, Evalue=2e-27,
Organism=Escherichia coli, GI1786911, Length=207, Percent_Identity=33.3333333333333, Blast_Score=110, Evalue=6e-26,
Organism=Escherichia coli, GI1788394, Length=221, Percent_Identity=36.6515837104072, Blast_Score=109, Evalue=2e-25,
Organism=Escherichia coli, GI1786599, Length=220, Percent_Identity=31.3636363636364, Blast_Score=105, Evalue=3e-24,
Organism=Escherichia coli, GI1790860, Length=222, Percent_Identity=32.8828828828829, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1787229, Length=224, Percent_Identity=32.1428571428571, Blast_Score=101, Evalue=4e-23,
Organism=Escherichia coli, GI1790863, Length=205, Percent_Identity=29.2682926829268, Blast_Score=75, Evalue=3e-15,
Organism=Escherichia coli, GI1788550, Length=151, Percent_Identity=27.1523178807947, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1790299, Length=133, Percent_Identity=29.3233082706767, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 25139; Mature: 25139

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00217 SUGAR_TRANSPORT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILIVEDDTLLLQGLILAAQTEGYACDGVSTARAAEHSLESGHYSLMVLDLGLPDEDGL
CEEEEEECCHHHHHHHHEEECCCCEEECCCCHHHHHHHHHCCCCEEEEEEEECCCCCCCH
HFLTRIRQKKYTLPVLILTARDTLNDRISGLDVGADDYLVKPFALEELHARIRALLRRHN
HHHHHHHHCCCCCCEEEEEECCCHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHHHHCC
NQGESELTVGNLTLNIGRHQAWRDGQELTLTPKEYALLSRLMLKAGSPVHREILYNDIYN
CCCCCEEEEEEEEEECCCCCCCCCCCEEEECHHHHHHHHHHHHHCCCCHHHHHHHHHHHC
WDNEPSTNTLEVHIHNLRDKVGKSRIRTVRRFGYMLVATEES
CCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHCCEEEEEECCC
>Mature Secondary Structure
MKILIVEDDTLLLQGLILAAQTEGYACDGVSTARAAEHSLESGHYSLMVLDLGLPDEDGL
CEEEEEECCHHHHHHHHEEECCCCEEECCCCHHHHHHHHHCCCCEEEEEEEECCCCCCCH
HFLTRIRQKKYTLPVLILTARDTLNDRISGLDVGADDYLVKPFALEELHARIRALLRRHN
HHHHHHHHCCCCCCEEEEEECCCHHHHHCCCCCCCCCEEECCHHHHHHHHHHHHHHHHCC
NQGESELTVGNLTLNIGRHQAWRDGQELTLTPKEYALLSRLMLKAGSPVHREILYNDIYN
CCCCCEEEEEEEEEECCCCCCCCCCCEEEECHHHHHHHHHHHHHCCCCHHHHHHHHHHHC
WDNEPSTNTLEVHIHNLRDKVGKSRIRTVRRFGYMLVATEES
CCCCCCCCEEEEEEEHHHHHHHHHHHHHHHHCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8282725; 7610040; 9278503 [H]