Click here to switch to the map view.

The map label for this gene is nirC [H]

Identifier: 29144296

GI number: 29144296

Start: 4186823

End: 4187632

Strand: Reverse

Name: nirC [H]

Synonym: t4029

Alternate gene names: 29144296

Gene position: 4187632-4186823 (Counterclockwise)

Preceding gene: 29144297

Following gene: 29144295

Centisome position: 87.39

GC content: 56.05

Gene sequence:

>810_bases
ATGTTTACAGACACTATTAATAAGTGTGCGGCTAACGCTGCGCGCATCGCACGCCTGTCGGCGAATAATCCGCTCGGCTT
CTGGGTCAGTTCGGCAATGGCCGGGGCTTATGTCGGTCTCGGCATCATTCTTATTTTCACCCTCGGCAATCTGCTCGACC
CGTCCGTGCGTCCTTTGGTGATGGGAGCCACCTTCGGTATCGCCTTAACGCTGGTCATCATCGCCGGTTCCGAACTGTTT
ACCGGCCACACCATGTTCCTGACGCTGGGCGTCAAAGCGGGCACCATCAGCCACGGTCAAATGTGGGCTATCCTGCCGCA
AACCTGGCTCGGCAACCTGGTTGGTTCCGTGTTTGTCGCCCTGCTTTACAGCTGGGGCGGCGGCAGTTTGTTGCCGGTCG
ATACCAGTATCGTTCACTCAGTCGCGCTGGCGAAAACCACCGCGCCCGCCACGGTACTGTTCTTCAAAGGCGCGCTGTGT
AACTGGCTGGTTTGTCTGGCAATCTGGATGGCGATCCGCACCGAAGGCACGGCAAAATTTCTTGCTATCTGGTGGTGTCT
GCTGGCGTTTATCGCTTCCGGCTACGAGCACTCCGTCGCGAATATGACGCTGTTCGCCCTCTCCTGGTTTGGCCATCACA
GCGATGCCTATACCCTGTCCGGAATCGGACACAATCTGTTATGGGTCACTCTGGGCAATACTTTGTCCGGCGTCGTGTTC
ATGGGATTGGGTTATTGGTATGCTACGCCGAAATCGGAGCGCCCTGTTCCGCAAAAAACCAACCAAATTAAGGCTACAGC
CAACCATTAA

Upstream 100 bases:

>100_bases
ATCAGGCAATTGCAAAAGCACATTGCCGGATGGCGGCATAAACGCCTTATCCGGCCTACGGTTACGATTTTTTTGTTTTT
TATACTTCAAGGATAATCAA

Downstream 100 bases:

>100_bases
GGGGTAATGTCGTGGACCATTTGCCTATATTTTGTCAATTGCGCGACCGCGACTGTCTGATCGTCGGCGGTGGCGATGTC
GCAGAACGCAAAGCACGGTT

Product: nitrite transporter NirC

Products: Proton [Cytoplasm]; nitrite [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MFTDTINKCAANAARIARLSANNPLGFWVSSAMAGAYVGLGIILIFTLGNLLDPSVRPLVMGATFGIALTLVIIAGSELF
TGHTMFLTLGVKAGTISHGQMWAILPQTWLGNLVGSVFVALLYSWGGGSLLPVDTSIVHSVALAKTTAPATVLFFKGALC
NWLVCLAIWMAIRTEGTAKFLAIWWCLLAFIASGYEHSVANMTLFALSWFGHHSDAYTLSGIGHNLLWVTLGNTLSGVVF
MGLGYWYATPKSERPVPQKTNQIKATANH

Sequences:

>Translated_269_residues
MFTDTINKCAANAARIARLSANNPLGFWVSSAMAGAYVGLGIILIFTLGNLLDPSVRPLVMGATFGIALTLVIIAGSELF
TGHTMFLTLGVKAGTISHGQMWAILPQTWLGNLVGSVFVALLYSWGGGSLLPVDTSIVHSVALAKTTAPATVLFFKGALC
NWLVCLAIWMAIRTEGTAKFLAIWWCLLAFIASGYEHSVANMTLFALSWFGHHSDAYTLSGIGHNLLWVTLGNTLSGVVF
MGLGYWYATPKSERPVPQKTNQIKATANH
>Mature_269_residues
MFTDTINKCAANAARIARLSANNPLGFWVSSAMAGAYVGLGIILIFTLGNLLDPSVRPLVMGATFGIALTLVIIAGSELF
TGHTMFLTLGVKAGTISHGQMWAILPQTWLGNLVGSVFVALLYSWGGGSLLPVDTSIVHSVALAKTTAPATVLFFKGALC
NWLVCLAIWMAIRTEGTAKFLAIWWCLLAFIASGYEHSVANMTLFALSWFGHHSDAYTLSGIGHNLLWVTLGNTLSGVVF
MGLGYWYATPKSERPVPQKTNQIKATANH

Specific function: May act as a nitrite transporter [H]

COG id: COG2116

COG function: function code P; Formate/nitrite family of transporters

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FNT transporter (TC 2.A.44) family [H]

Homologues:

Organism=Escherichia coli, GI87082249, Length=267, Percent_Identity=92.1348314606742, Blast_Score=498, Evalue=1e-142,
Organism=Escherichia coli, GI1787132, Length=260, Percent_Identity=28.4615384615385, Blast_Score=70, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6321779, Length=211, Percent_Identity=28.436018957346, Blast_Score=70, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000292 [H]

Pfam domain/function: PF01226 Form_Nir_trans [H]

EC number: NA

Molecular weight: Translated: 28793; Mature: 28793

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: PS01005 FORMATE_NITRITE_TP_1 ; PS01006 FORMATE_NITRITE_TP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFTDTINKCAANAARIARLSANNPLGFWVSSAMAGAYVGLGIILIFTLGNLLDPSVRPLV
CCCCHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
MGATFGIALTLVIIAGSELFTGHTMFLTLGVKAGTISHGQMWAILPQTWLGNLVGSVFVA
EHHHHHHHHHHHHHCCCCHHCCEEEEEEEECCCCCCCCCCEEEECHHHHHHHHHHHHHHH
LLYSWGGGSLLPVDTSIVHSVALAKTTAPATVLFFKGALCNWLVCLAIWMAIRTEGTAKF
HHHHCCCCCEEECCHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LAIWWCLLAFIASGYEHSVANMTLFALSWFGHHSDAYTLSGIGHNLLWVTLGNTLSGVVF
HHHHHHHHHHHHCCCCHHHHHHHEEEEHHHCCCCCCEEECCCCCEEEEEEECCHHHHHHH
MGLGYWYATPKSERPVPQKTNQIKATANH
HHHHHEEECCCCCCCCCCCCCCEEEECCC
>Mature Secondary Structure
MFTDTINKCAANAARIARLSANNPLGFWVSSAMAGAYVGLGIILIFTLGNLLDPSVRPLV
CCCCHHHHHHHHHHHHEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEE
MGATFGIALTLVIIAGSELFTGHTMFLTLGVKAGTISHGQMWAILPQTWLGNLVGSVFVA
EHHHHHHHHHHHHHCCCCHHCCEEEEEEEECCCCCCCCCCEEEECHHHHHHHHHHHHHHH
LLYSWGGGSLLPVDTSIVHSVALAKTTAPATVLFFKGALCNWLVCLAIWMAIRTEGTAKF
HHHHCCCCCEEECCHHHHHHHHHHHCCCCEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
LAIWWCLLAFIASGYEHSVANMTLFALSWFGHHSDAYTLSGIGHNLLWVTLGNTLSGVVF
HHHHHHHHHHHHCCCCHHHHHHHEEEEHHHCCCCCCEEECCCCCEEEEEEECCHHHHHHH
MGLGYWYATPKSERPVPQKTNQIKATANH
HHHHHEEECCCCCCCCCCCCCCEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; nitrite [Periplasm] [C]

Specific reaction: Proton [Periplasm] + nitrite [Periplasm] = Proton [Cytoplasm] + nitrite [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1987123; 11677609 [H]