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The map label for this gene is aroB [H]

Identifier: 29144288

GI number: 29144288

Start: 4173072

End: 4174160

Strand: Direct

Name: aroB [H]

Synonym: t4020

Alternate gene names: 29144288

Gene position: 4173072-4174160 (Clockwise)

Preceding gene: 29144287

Following gene: 29144289

Centisome position: 87.08

GC content: 55.74

Gene sequence:

>1089_bases
ATGGAGAGGATTACAGTCACTCTCGGGGAACGTAGTTACCCGATCACCATCGCGGCTGGTTTGTTTAACGAACCAGCTTC
ATTCTTGCCGCTGAAATCAGGCGATCAGGTCATGTTAGTGACCAACGAAACCCTGGCGCCGCTTTATCTGGACAAGGTTC
GCGGCGTACTCGAACGGGCGGGCGTTAACGTAGACAGCGTGATTCTTCCTGACGGCGAGCAGTATAAGAGCCTGACGGTG
CTGGATACGGTGTTTACGGCGTTACTGAAAAAACCGCATGGTCGTGATACCACGCTGGTCGCGCTTGGCGGCGGCGTGAT
TGGCGATCTTACCGGTTTTGCGGCGGCCAGCTACCAGCGAGGCGTTCGTTTCATCCAGGTGCCAACTACCTTACTGTCGC
AGGTTGATTCTTCCGTGGGCGGGAAGACCGCCGTCAACCATCCCCTTGGCAAAAACATGATTGGCGCGTTTTACCAACCC
GCTTCTGTGGTTGTCGATCTTGATTGCCTGAAAACGCTTCCCGCACGCGAACTGGCATCGGGACTGGCAGAGGTGATCAA
ATACGGCATTATACTCGACGCAGACTTCTTCACCTGGCTTGAGGGTAATCTGGATGCGCTATTGCGTCTGGACGGCCCGG
CGATGGCGTACTGTATTCGTCGTTGTTGCGAGCTGAAAGCCGAAGTTGTTGCCGCCGACGAGCGTGAAGCGGGCTTACGT
GCTTTACTGAATCTTGGGCATACCTTTGGCCACGCCATTGAAGCGGAAATGGGATATGGCAATTGGTTACATGGTGAAGC
CGTTGCCGCAGGTATAGTGATGGCTGCGCGCGCATCCGAGCGTTTGGGGCAGTTCAGTTCTGCTGATACGCAGCGCATCA
TCGCGCTACTCGAACGGGCCGGGTTGCCAGTCAATGGCCCTTGCGAGATGTCCGCGCAGGACTATTTGCCGCACATGCTG
CGAGATAAAAAAGTGTTAGCGGGGGAGCTGCGTTTAGTGCTTCCGCTGACCATAGGGAAAAGTGAAGTGCGCGGCGGAGT
GTCGCACGAAGTCGTTCTTAGCGCGATTGCTGACTGTCAGCAGGCGTAA

Upstream 100 bases:

>100_bases
AGGTTGTGGCAAACCAGATTATTCATATGCTGGAAAGCAACTAATTCAAGCAGAATACGCTGGGTAAGCGGGCACAAGTA
ACTAAGGTGGATGTCGCGTC

Downstream 100 bases:

>100_bases
CAACAAGAAAGGTCAGACTGATATTGCGTAGCTGTCAGTCTTTTAGCTTCAGGTTATGTGCAATGTCGTAAGCATTAACC
TTTGAGTGGGGTGTTAAATG

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 362; Mature: 362

Protein sequence:

>362_residues
MERITVTLGERSYPITIAAGLFNEPASFLPLKSGDQVMLVTNETLAPLYLDKVRGVLERAGVNVDSVILPDGEQYKSLTV
LDTVFTALLKKPHGRDTTLVALGGGVIGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQP
ASVVVDLDCLKTLPARELASGLAEVIKYGIILDADFFTWLEGNLDALLRLDGPAMAYCIRRCCELKAEVVAADEREAGLR
ALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGIVMAARASERLGQFSSADTQRIIALLERAGLPVNGPCEMSAQDYLPHML
RDKKVLAGELRLVLPLTIGKSEVRGGVSHEVVLSAIADCQQA

Sequences:

>Translated_362_residues
MERITVTLGERSYPITIAAGLFNEPASFLPLKSGDQVMLVTNETLAPLYLDKVRGVLERAGVNVDSVILPDGEQYKSLTV
LDTVFTALLKKPHGRDTTLVALGGGVIGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQP
ASVVVDLDCLKTLPARELASGLAEVIKYGIILDADFFTWLEGNLDALLRLDGPAMAYCIRRCCELKAEVVAADEREAGLR
ALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGIVMAARASERLGQFSSADTQRIIALLERAGLPVNGPCEMSAQDYLPHML
RDKKVLAGELRLVLPLTIGKSEVRGGVSHEVVLSAIADCQQA
>Mature_362_residues
MERITVTLGERSYPITIAAGLFNEPASFLPLKSGDQVMLVTNETLAPLYLDKVRGVLERAGVNVDSVILPDGEQYKSLTV
LDTVFTALLKKPHGRDTTLVALGGGVIGDLTGFAAASYQRGVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQP
ASVVVDLDCLKTLPARELASGLAEVIKYGIILDADFFTWLEGNLDALLRLDGPAMAYCIRRCCELKAEVVAADEREAGLR
ALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGIVMAARASERLGQFSSADTQRIIALLERAGLPVNGPCEMSAQDYLPHML
RDKKVLAGELRLVLPLTIGKSEVRGGVSHEVVLSAIADCQQA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family [H]

Homologues:

Organism=Escherichia coli, GI1789791, Length=362, Percent_Identity=92.5414364640884, Blast_Score=667, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6320332, Length=313, Percent_Identity=40.2555910543131, Blast_Score=197, Evalue=3e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037 [H]

Pfam domain/function: PF01761 DHQ_synthase [H]

EC number: =4.2.3.4 [H]

Molecular weight: Translated: 38710; Mature: 38710

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERITVTLGERSYPITIAAGLFNEPASFLPLKSGDQVMLVTNETLAPLYLDKVRGVLERA
CCEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHC
GVNVDSVILPDGEQYKSLTVLDTVFTALLKKPHGRDTTLVALGGGVIGDLTGFAAASYQR
CCCCCEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHC
GVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPASVVVDLDCLKTLPARELAS
CCEEEEEHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCCEEEEHHHHHCCCHHHHHH
GLAEVIKYGIILDADFFTWLEGNLDALLRLDGPAMAYCIRRCCELKAEVVAADEREAGLR
HHHHHHHHCEEEECHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHHH
ALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGIVMAARASERLGQFSSADTQRIIALLERA
HHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHC
GLPVNGPCEMSAQDYLPHMLRDKKVLAGELRLVLPLTIGKSEVRGGVSHEVVLSAIADCQ
CCCCCCCCCCCHHHHHHHHHHCCHHHHCCEEEEEEEEECHHHHCCCCHHHHHHHHHHHHH
QA
CC
>Mature Secondary Structure
MERITVTLGERSYPITIAAGLFNEPASFLPLKSGDQVMLVTNETLAPLYLDKVRGVLERA
CCEEEEEECCCCCCEEEEECCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHC
GVNVDSVILPDGEQYKSLTVLDTVFTALLKKPHGRDTTLVALGGGVIGDLTGFAAASYQR
CCCCCEEECCCCHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHHHHHHHHHHC
GVRFIQVPTTLLSQVDSSVGGKTAVNHPLGKNMIGAFYQPASVVVDLDCLKTLPARELAS
CCEEEEEHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHCCCCCEEEEHHHHHCCCHHHHHH
GLAEVIKYGIILDADFFTWLEGNLDALLRLDGPAMAYCIRRCCELKAEVVAADEREAGLR
HHHHHHHHCEEEECHHHHHHCCCCEEEEEECCHHHHHHHHHHHHHHHHHHCCCCHHHHHH
ALLNLGHTFGHAIEAEMGYGNWLHGEAVAAGIVMAARASERLGQFSSADTQRIIALLERA
HHHHHHHHHHHHEEECCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHC
GLPVNGPCEMSAQDYLPHMLRDKKVLAGELRLVLPLTIGKSEVRGGVSHEVVLSAIADCQ
CCCCCCCCCCCHHHHHHHHHHCCHHHHCCEEEEEEEEECHHHHCCCCHHHHHHHHHHHHH
QA
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA