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The map label for this gene is bcsA

Identifier: 29144171

GI number: 29144171

Start: 4024596

End: 4027220

Strand: Direct

Name: bcsA

Synonym: t3898

Alternate gene names: 29144171

Gene position: 4024596-4027220 (Clockwise)

Preceding gene: 29144170

Following gene: 29144172

Centisome position: 83.99

GC content: 55.54

Gene sequence:

>2625_bases
ATGAGCGCCCTTTCCCGGTGGCTGCTTATCCCGCCGGTTAGCGCGCGCTTGAGCGAGCGCTATCAGGGTTACCGCCGCCA
CGGCGCGTCGCCGTTTAGCGCAGCGCTCGGCTGCCTGTGGACGATTCTGGCGTGGATAGTGTTTCCGCTTGAGCATCCGC
GCTGGCAGCGTATTCGCGACGGGCATAAAGCGCTTTATCCGCATATTAACGCCGCCCGCCCGCGCCCGCTGGACCCGGCC
CGTTACCTCATTCAGACCCTCTGGCTGGTGATGATCTCGTCGACTAAAGAACGTCATGAACCGCGCTGGCGGTCATTTGC
GCGCCTGAAGGACGTTCGTGGACGTTACCATCAATGGATGGATACCTTACCGGAACGGGTGCGCCAAAAGACAACGCACC
TGGAAAAGGAAAAAGAGCTGGGACATCTTAGCAACGGCGCCCGGCGTTTTATTCTGGGCGTTATCGTGACCTTTTCACTG
ATACTGGCGCTGATCTGTATTACGCAGCCATTTAACCCGCTATCGCAATTTATCTTTCTGCTGTTGCTGTGGGGCGTTGC
GCTGTTGGTACGACGTATGCCGGGACGCTTTTCCGCGCTGATGCTCATCGTGCTGTCGCTAACGGTCTCCTGTCGTTATA
TCTGGTGGCGCTATACCTCGACGCTAAATTGGGACGACCCGGTCAGTCTGGTGTGCGGACTGATTCTGCTGTTTGCGGAA
ACCTACGCCTGGATTGTGCTGGTGCTGGGGTACTTCCAGGTGGTGTGGCCGTTAAATCGTCAACCGGTGCCGTTGCCGAA
AGAGATGTCGCAGTGGCCGACGGTGGATATTTTTGTACCGACCTATAACGAAGACCTTAATGTGGTCAAAAATACCATTT
ACGCTTCGCTTGGCATTGACTGGCCGAAGGACAAGCTGAATATCTGGATCCTTGATGACGGCGGGCGCGAATCATTTCGT
CAGTTTGCCCGGCATGTTGGCGTGCATTACATTGCCCGCGCTACGCATGAACACGCCAAAGCCGGCAACATCAACAATGC
GTTAAAACACGCGAAAGGCGAGTTTGTGGCGATCTTCGATTGCGACCATGTACCGACGCGCTCGTTTCTGCAAATGACAA
TGGGCTGGTTCCTGAAAGAGAAACAGCTGGCGATGATGCAGACGCCGCATCATTTCTTCTCCCCGGACCCGTTTGAGCGC
AACCTGGGACGTTTTCGTAAAACGCCTAACGAAGGCACGCTGTTTTACGGACTGGTGCAGGACGGTAACGATATGTGGGA
TGCCACTTTCTTTTGCGGATCGTGCGCGGTGATTCGCCGTAAGCCGCTGGATGAGATTGGCGGTATCGCCGTTGAGACGG
TGACGGAAGATGCGCATACTTCGCTCCGGCTGCACCGGCGAGGTTATACCTCAGCGTATATGCGCATTCCGCAGTCGGCG
GGGCTGGCGACGGAAAGCCTGTCGGCGCATATCGGGCAGCGTATTCGTTGGGCGCGGGGCATGGTGCAAATTTTCCGCCT
CGATAACCCTCTGTTTGGTAAAGGCTTAAAACTGGCGCAGCGGCTGTGCTACCTCAACGCGATGTTCCATTTCTTGTCCG
GCATTCCGCGCCTGATCTTTCTGACCGCGCCGCTGGCTTTTCTGCTGCTGCACGCCTATATCATTTATGCGCCTGCGTTG
ATGATTGCGCTATTTGTGATACCGCACATGGTCCACGCCAGCCTGACTAACTCGAAGATTCAGGGCAAGTATCGTCACTC
TTTCTGGAGTGAAATCTATGAAACGGTACTGGCATGGTATATCGCACCACCGACTCTGGTCGCGTTGATCAATCCGCACA
AAGGGAAATTTAACGTCACGGCGAAAGGCGGACTGGTGGAAGAGAAGTACGTCGACTGGGTAATCTCGCGTCCGTATATC
TTCCTTGTCTTGCTTAACCTGCTCGGCGTGGCGGCGGGCGTATGGCGATACTATTATGGGCCGGAAAATGAAACGCTGAC
CGTCATCGTTAGCCTGGTGTGGGTCTTCTATAACCTGGTCATTCTCGGCGGCGCGGTTGCGGTTTCGGTAGAGAGTAAAC
AGGTCAGGCGCGCGCATCGGGTCGAGATTGCCATGCCGGGGGCCATCGCCCGCGAAGATGGACATTTGTTCTCCTGTACC
GTACATGACTTCTCCGACGGCGGGTTAGGCATCAAGATCAACGGTCAGGCGCAGGTGCTGGAAGGGCAGAAAGTGAATCT
GTTGCTTAAACGCGGGCAGCAGGAATATGTCTTTCCAACGCAGGTAGTGCGCGTAACGGGCAATGAGGTCGGGCTGCAAC
TGATGCCGCTCACCACCAAACAACATATTGATTTTGTGCAGTGTACCTTCGCTCGCGCCGATACGTGGGCGCTTTGGCAA
GATAGCTTCCCGGAAGATAAACCGCTGGAAAGCTTGCTGGATATTCTGAAGCTGGGCTTCCGCGGATATCGCCACCTCGC
GGAGTTCGCGCCGCCTTCAGTAAAAGTAATTTTCCGATCGTTGACGGCGTTAATTGCCTGGATTGTATCGTTTATTCCGC
GTCGCCCGGAGCGGCAAGCGGCGATACAGCCGTCGGATCGGGTTATGGCTCAGGCTCAACAATGA

Upstream 100 bases:

>100_bases
AGTATCGCAGCGATTCGTTAGCCGCCGAAGAGGTGTTAACGCTGGCGAACTGGTGCCTGCTGCACGATGCGGGCGACAAA
ACGTCTGCCGGGAGCCTGCG

Downstream 100 bases:

>100_bases
TGATAATGCGATGAAAAGAAAATTGTCCTGGATGTGTGCGGCGGTAATAGGATTAAGCGCGTTTCCTGCTTTCATGACGG
CGGCGGCGCCTGCGATGCCG

Product: cellulose synthase catalytic subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 874; Mature: 873

Protein sequence:

>874_residues
MSALSRWLLIPPVSARLSERYQGYRRHGASPFSAALGCLWTILAWIVFPLEHPRWQRIRDGHKALYPHINAARPRPLDPA
RYLIQTLWLVMISSTKERHEPRWRSFARLKDVRGRYHQWMDTLPERVRQKTTHLEKEKELGHLSNGARRFILGVIVTFSL
ILALICITQPFNPLSQFIFLLLLWGVALLVRRMPGRFSALMLIVLSLTVSCRYIWWRYTSTLNWDDPVSLVCGLILLFAE
TYAWIVLVLGYFQVVWPLNRQPVPLPKEMSQWPTVDIFVPTYNEDLNVVKNTIYASLGIDWPKDKLNIWILDDGGRESFR
QFARHVGVHYIARATHEHAKAGNINNALKHAKGEFVAIFDCDHVPTRSFLQMTMGWFLKEKQLAMMQTPHHFFSPDPFER
NLGRFRKTPNEGTLFYGLVQDGNDMWDATFFCGSCAVIRRKPLDEIGGIAVETVTEDAHTSLRLHRRGYTSAYMRIPQSA
GLATESLSAHIGQRIRWARGMVQIFRLDNPLFGKGLKLAQRLCYLNAMFHFLSGIPRLIFLTAPLAFLLLHAYIIYAPAL
MIALFVIPHMVHASLTNSKIQGKYRHSFWSEIYETVLAWYIAPPTLVALINPHKGKFNVTAKGGLVEEKYVDWVISRPYI
FLVLLNLLGVAAGVWRYYYGPENETLTVIVSLVWVFYNLVILGGAVAVSVESKQVRRAHRVEIAMPGAIAREDGHLFSCT
VHDFSDGGLGIKINGQAQVLEGQKVNLLLKRGQQEYVFPTQVVRVTGNEVGLQLMPLTTKQHIDFVQCTFARADTWALWQ
DSFPEDKPLESLLDILKLGFRGYRHLAEFAPPSVKVIFRSLTALIAWIVSFIPRRPERQAAIQPSDRVMAQAQQ

Sequences:

>Translated_874_residues
MSALSRWLLIPPVSARLSERYQGYRRHGASPFSAALGCLWTILAWIVFPLEHPRWQRIRDGHKALYPHINAARPRPLDPA
RYLIQTLWLVMISSTKERHEPRWRSFARLKDVRGRYHQWMDTLPERVRQKTTHLEKEKELGHLSNGARRFILGVIVTFSL
ILALICITQPFNPLSQFIFLLLLWGVALLVRRMPGRFSALMLIVLSLTVSCRYIWWRYTSTLNWDDPVSLVCGLILLFAE
TYAWIVLVLGYFQVVWPLNRQPVPLPKEMSQWPTVDIFVPTYNEDLNVVKNTIYASLGIDWPKDKLNIWILDDGGRESFR
QFARHVGVHYIARATHEHAKAGNINNALKHAKGEFVAIFDCDHVPTRSFLQMTMGWFLKEKQLAMMQTPHHFFSPDPFER
NLGRFRKTPNEGTLFYGLVQDGNDMWDATFFCGSCAVIRRKPLDEIGGIAVETVTEDAHTSLRLHRRGYTSAYMRIPQSA
GLATESLSAHIGQRIRWARGMVQIFRLDNPLFGKGLKLAQRLCYLNAMFHFLSGIPRLIFLTAPLAFLLLHAYIIYAPAL
MIALFVIPHMVHASLTNSKIQGKYRHSFWSEIYETVLAWYIAPPTLVALINPHKGKFNVTAKGGLVEEKYVDWVISRPYI
FLVLLNLLGVAAGVWRYYYGPENETLTVIVSLVWVFYNLVILGGAVAVSVESKQVRRAHRVEIAMPGAIAREDGHLFSCT
VHDFSDGGLGIKINGQAQVLEGQKVNLLLKRGQQEYVFPTQVVRVTGNEVGLQLMPLTTKQHIDFVQCTFARADTWALWQ
DSFPEDKPLESLLDILKLGFRGYRHLAEFAPPSVKVIFRSLTALIAWIVSFIPRRPERQAAIQPSDRVMAQAQQ
>Mature_873_residues
SALSRWLLIPPVSARLSERYQGYRRHGASPFSAALGCLWTILAWIVFPLEHPRWQRIRDGHKALYPHINAARPRPLDPAR
YLIQTLWLVMISSTKERHEPRWRSFARLKDVRGRYHQWMDTLPERVRQKTTHLEKEKELGHLSNGARRFILGVIVTFSLI
LALICITQPFNPLSQFIFLLLLWGVALLVRRMPGRFSALMLIVLSLTVSCRYIWWRYTSTLNWDDPVSLVCGLILLFAET
YAWIVLVLGYFQVVWPLNRQPVPLPKEMSQWPTVDIFVPTYNEDLNVVKNTIYASLGIDWPKDKLNIWILDDGGRESFRQ
FARHVGVHYIARATHEHAKAGNINNALKHAKGEFVAIFDCDHVPTRSFLQMTMGWFLKEKQLAMMQTPHHFFSPDPFERN
LGRFRKTPNEGTLFYGLVQDGNDMWDATFFCGSCAVIRRKPLDEIGGIAVETVTEDAHTSLRLHRRGYTSAYMRIPQSAG
LATESLSAHIGQRIRWARGMVQIFRLDNPLFGKGLKLAQRLCYLNAMFHFLSGIPRLIFLTAPLAFLLLHAYIIYAPALM
IALFVIPHMVHASLTNSKIQGKYRHSFWSEIYETVLAWYIAPPTLVALINPHKGKFNVTAKGGLVEEKYVDWVISRPYIF
LVLLNLLGVAAGVWRYYYGPENETLTVIVSLVWVFYNLVILGGAVAVSVESKQVRRAHRVEIAMPGAIAREDGHLFSCTV
HDFSDGGLGIKINGQAQVLEGQKVNLLLKRGQQEYVFPTQVVRVTGNEVGLQLMPLTTKQHIDFVQCTFARADTWALWQD
SFPEDKPLESLLDILKLGFRGYRHLAEFAPPSVKVIFRSLTALIAWIVSFIPRRPERQAAIQPSDRVMAQAQQ

Specific function: Catalytic subunit of cellulose synthase. It polymerizes uridine 5'-diphosphate glucose to cellulose, which is produced as an extracellular component for mechanical and chemical protection at the onset of the stationary phase, when the cells exhibit multic

COG id: COG1215

COG function: function code M; Glycosyltransferases, probably involved in cell wall biogenesis

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PilZ domain

Homologues:

Organism=Escherichia coli, GI87082284, Length=871, Percent_Identity=88.2893226176808, Blast_Score=1620, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): BCSA_SALTI (Q8Z291)

Other databases:

- EMBL:   AL627281
- EMBL:   AE014613
- RefSeq:   NP_458301.1
- RefSeq:   NP_807513.1
- ProteinModelPortal:   Q8Z291
- GeneID:   1071208
- GeneID:   1250405
- GenomeReviews:   AE014613_GR
- GenomeReviews:   AL513382_GR
- KEGG:   stt:t3898
- KEGG:   sty:STY4181
- HOGENOM:   HBG632848
- OMA:   CYANAML
- ProtClustDB:   PRK11498
- BioCyc:   SENT209261:T3898-MONOMER
- BioCyc:   SENT220341:STY4181-MONOMER
- BRENDA:   2.4.1.12
- InterPro:   IPR003919
- InterPro:   IPR001173
- InterPro:   IPR009875
- PRINTS:   PR01439
- TIGRFAMs:   TIGR03030

Pfam domain/function: PF00535 Glycos_transf_2; PF07238 PilZ

EC number: =2.4.1.12

Molecular weight: Translated: 100022; Mature: 99891

Theoretical pI: Translated: 10.03; Mature: 10.03

Prosite motif: NA

Important sites: ACT_SITE 313-313 ACT_SITE 457-457 BINDING 360-360 BINDING 362-362

Signals:

None

Transmembrane regions:

HASH(0x40e02768)-; HASH(0x11f62eb0)-; HASH(0xf14cb3c)-; HASH(0xb0cffbc)-; HASH(0x12a77458)-; HASH(0x12a0f548)-; HASH(0x1135860c)-; HASH(0x40e20e64)-; HASH(0x11cac290)-; HASH(0x128de288)-;

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSALSRWLLIPPVSARLSERYQGYRRHGASPFSAALGCLWTILAWIVFPLEHPRWQRIRD
CCCCCCCEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHC
GHKALYPHINAARPRPLDPARYLIQTLWLVMISSTKERHEPRWRSFARLKDVRGRYHQWM
CHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHH
DTLPERVRQKTTHLEKEKELGHLSNGARRFILGVIVTFSLILALICITQPFNPLSQFIFL
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
LLLWGVALLVRRMPGRFSALMLIVLSLTVSCRYIWWRYTSTLNWDDPVSLVCGLILLFAE
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCHHHHHHHHHHHHHH
TYAWIVLVLGYFQVVWPLNRQPVPLPKEMSQWPTVDIFVPTYNEDLNVVKNTIYASLGID
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCEEEEEECCCCCCHHHHHHHHHHHCCCC
WPKDKLNIWILDDGGRESFRQFARHVGVHYIARATHEHAKAGNINNALKHAKGEFVAIFD
CCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEEE
CDHVPTRSFLQMTMGWFLKEKQLAMMQTPHHFFSPDPFERNLGRFRKTPNEGTLFYGLVQ
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEE
DGNDMWDATFFCGSCAVIRRKPLDEIGGIAVETVTEDAHTSLRLHRRGYTSAYMRIPQSA
CCCCHHHHHHHHCCHHHHHCCCHHHHCCEEEEEECCHHHHHHHHHHCCCCHHHHCCCCCC
GLATESLSAHIGQRIRWARGMVQIFRLDNPLFGKGLKLAQRLCYLNAMFHFLSGIPRLIF
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHH
LTAPLAFLLLHAYIIYAPALMIALFVIPHMVHASLTNSKIQGKYRHSFWSEIYETVLAWY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHH
IAPPTLVALINPHKGKFNVTAKGGLVEEKYVDWVISRPYIFLVLLNLLGVAAGVWRYYYG
CCCCEEEEEECCCCCEEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEEC
PENETLTVIVSLVWVFYNLVILGGAVAVSVESKQVRRAHRVEIAMPGAIAREDGHLFSCT
CCCCHHHHHHHHHHHHHHHHHHCCHHEEEECHHHHHHHHHEEEECCCCEECCCCCEEEEE
VHDFSDGGLGIKINGQAQVLEGQKVNLLLKRGQQEYVFPTQVVRVTGNEVGLQLMPLTTK
EEECCCCCEEEEECCCEEEECCCHHHHHHHCCCCCCCCCHHEEEEECCCCCEEEEECCHH
QHIDFVQCTFARADTWALWQDSFPEDKPLESLLDILKLGFRGYRHLAEFAPPSVKVIFRS
HHCCHHHEEHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
LTALIAWIVSFIPRRPERQAAIQPSDRVMAQAQQ
HHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCH
>Mature Secondary Structure 
SALSRWLLIPPVSARLSERYQGYRRHGASPFSAALGCLWTILAWIVFPLEHPRWQRIRD
CCCCCCEECCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHC
GHKALYPHINAARPRPLDPARYLIQTLWLVMISSTKERHEPRWRSFARLKDVRGRYHQWM
CHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHH
DTLPERVRQKTTHLEKEKELGHLSNGARRFILGVIVTFSLILALICITQPFNPLSQFIFL
HHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
LLLWGVALLVRRMPGRFSALMLIVLSLTVSCRYIWWRYTSTLNWDDPVSLVCGLILLFAE
HHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEEEEEEECCCCCCCHHHHHHHHHHHHHH
TYAWIVLVLGYFQVVWPLNRQPVPLPKEMSQWPTVDIFVPTYNEDLNVVKNTIYASLGID
HHHHHHHHHHHHHHHCCCCCCCCCCCHHHHCCCEEEEEECCCCCCHHHHHHHHHHHCCCC
WPKDKLNIWILDDGGRESFRQFARHVGVHYIARATHEHAKAGNINNALKHAKGEFVAIFD
CCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCEEEEEE
CDHVPTRSFLQMTMGWFLKEKQLAMMQTPHHFFSPDPFERNLGRFRKTPNEGTLFYGLVQ
CCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCCCEEEEEEE
DGNDMWDATFFCGSCAVIRRKPLDEIGGIAVETVTEDAHTSLRLHRRGYTSAYMRIPQSA
CCCCHHHHHHHHCCHHHHHCCCHHHHCCEEEEEECCHHHHHHHHHHCCCCHHHHCCCCCC
GLATESLSAHIGQRIRWARGMVQIFRLDNPLFGKGLKLAQRLCYLNAMFHFLSGIPRLIF
CCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHCCCHHHHH
LTAPLAFLLLHAYIIYAPALMIALFVIPHMVHASLTNSKIQGKYRHSFWSEIYETVLAWY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCCHHHHHHHHHHHHHHHHHH
IAPPTLVALINPHKGKFNVTAKGGLVEEKYVDWVISRPYIFLVLLNLLGVAAGVWRYYYG
CCCCEEEEEECCCCCEEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHEEC
PENETLTVIVSLVWVFYNLVILGGAVAVSVESKQVRRAHRVEIAMPGAIAREDGHLFSCT
CCCCHHHHHHHHHHHHHHHHHHCCHHEEEECHHHHHHHHHEEEECCCCEECCCCCEEEEE
VHDFSDGGLGIKINGQAQVLEGQKVNLLLKRGQQEYVFPTQVVRVTGNEVGLQLMPLTTK
EEECCCCCEEEEECCCEEEECCCHHHHHHHCCCCCCCCCHHEEEEECCCCCEEEEECCHH
QHIDFVQCTFARADTWALWQDSFPEDKPLESLLDILKLGFRGYRHLAEFAPPSVKVIFRS
HHCCHHHEEHHCCCCEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHH
LTALIAWIVSFIPRRPERQAAIQPSDRVMAQAQQ
HHHHHHHHHHHHCCCCCCCCCCCCHHHHHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504