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The map label for this gene is tag [H]

Identifier: 29144153

GI number: 29144153

Start: 4003989

End: 4004570

Strand: Reverse

Name: tag [H]

Synonym: t3877

Alternate gene names: 29144153

Gene position: 4004570-4003989 (Counterclockwise)

Preceding gene: 29144156

Following gene: 29144152

Centisome position: 83.57

GC content: 51.72

Gene sequence:

>582_bases
ATGCAGCGTTGCGACTGGGTCAGCCAGGACCCCCTTTATATTGCCTATCATGATAACGAGTGGGGCGTACCGGAAACTGA
CAGCAGAAAGCTGTTTGAAATGATCTGTCTTGAAGGTCAACAGGCCGGTTTATCCTGGATCACCGTGCTTAAAAAGAGGG
AGAACTACCGCGCCTGTTTTCATCAGTTTGACCCGATACGCATCGCAGCTATGCAGGAGGAGGATGTTGAACGCCTGCTA
CAGAACACGGGCATCATACGACATCGCGGTAAAATTCAGGCCATTATCAGTAACGCCCGCGCCTGGCTTGCGATGGAGCA
AAACGGCGAGTCTTTCGCCGATTTTGTCTGGTCATTCGTTGATGGTCAGCCGCAGATCACCCAGGCGGCCAGCCTGGATA
AGATCCCCACCTCAACACCTGCGTCCGATGCGCTTGCTAAGGCATTGAAAAAACGCGGTTTCAAGTTTGTCGGTACGACT
ATCTGTTACTCCTTTATGCAGGCGTGCGGACTGGTCAACGACCATATTACCGGCTGTTTTTGCCATCCGGGAGAAAAACA
TGATTCGCAAATCCCAGAGTGA

Upstream 100 bases:

>100_bases
ATGTCGGACATCAGCCCTGTATTAACTATTGTCCTTTTAGCGGACCCGTCAAGGCGGGTTGAAGGAAATTTTCGCGGTAA
CCACAATAACGAGGAAGTCT

Downstream 100 bases:

>100_bases
AGACATGGCGTCTATTCTGGCGCTGTGGATGAAAAGTACCATTTATGCCCATCCCTTTATCGAAGAACGTTACTGGCACG
AGAGCGAAGCAATTGTACGC

Product: 3-methyl-adenine DNA glycosylase I

Products: NA

Alternate protein names: 3-methyladenine-DNA glycosylase I, constitutive; TAG I; DNA-3-methyladenine glycosidase I; DNA-3-methyladenine glycosylase I [H]

Number of amino acids: Translated: 193; Mature: 193

Protein sequence:

>193_residues
MQRCDWVSQDPLYIAYHDNEWGVPETDSRKLFEMICLEGQQAGLSWITVLKKRENYRACFHQFDPIRIAAMQEEDVERLL
QNTGIIRHRGKIQAIISNARAWLAMEQNGESFADFVWSFVDGQPQITQAASLDKIPTSTPASDALAKALKKRGFKFVGTT
ICYSFMQACGLVNDHITGCFCHPGEKHDSQIPE

Sequences:

>Translated_193_residues
MQRCDWVSQDPLYIAYHDNEWGVPETDSRKLFEMICLEGQQAGLSWITVLKKRENYRACFHQFDPIRIAAMQEEDVERLL
QNTGIIRHRGKIQAIISNARAWLAMEQNGESFADFVWSFVDGQPQITQAASLDKIPTSTPASDALAKALKKRGFKFVGTT
ICYSFMQACGLVNDHITGCFCHPGEKHDSQIPE
>Mature_193_residues
MQRCDWVSQDPLYIAYHDNEWGVPETDSRKLFEMICLEGQQAGLSWITVLKKRENYRACFHQFDPIRIAAMQEEDVERLL
QNTGIIRHRGKIQAIISNARAWLAMEQNGESFADFVWSFVDGQPQITQAASLDKIPTSTPASDALAKALKKRGFKFVGTT
ICYSFMQACGLVNDHITGCFCHPGEKHDSQIPE

Specific function: Hydrolysis of the deoxyribose N-glycosidic bond to excise 3-methyladenine from the damaged DNA polymer formed by alkylation lesions [H]

COG id: COG2818

COG function: function code L; 3-methyladenine DNA glycosylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1789971, Length=186, Percent_Identity=84.9462365591398, Blast_Score=346, Evalue=5e-97,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005019
- InterPro:   IPR011257
- InterPro:   IPR004597 [H]

Pfam domain/function: PF03352 Adenine_glyco [H]

EC number: =3.2.2.20 [H]

Molecular weight: Translated: 21913; Mature: 21913

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQRCDWVSQDPLYIAYHDNEWGVPETDSRKLFEMICLEGQQAGLSWITVLKKRENYRACF
CCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
HQFDPIRIAAMQEEDVERLLQNTGIIRHRGKIQAIISNARAWLAMEQNGESFADFVWSFV
HCCCCEEEEECCHHHHHHHHHHCCCEEECCHHHHHHHCCHHEEEECCCCCHHHHHHHHHH
DGQPQITQAASLDKIPTSTPASDALAKALKKRGFKFVGTTICYSFMQACGLVNDHITGCF
CCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHCCCCEEE
CHPGEKHDSQIPE
ECCCCCCCCCCCC
>Mature Secondary Structure
MQRCDWVSQDPLYIAYHDNEWGVPETDSRKLFEMICLEGQQAGLSWITVLKKRENYRACF
CCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
HQFDPIRIAAMQEEDVERLLQNTGIIRHRGKIQAIISNARAWLAMEQNGESFADFVWSFV
HCCCCEEEEECCHHHHHHHHHHCCCEEECCHHHHHHHCCHHEEEECCCCCHHHHHHHHHH
DGQPQITQAASLDKIPTSTPASDALAKALKKRGFKFVGTTICYSFMQACGLVNDHITGCF
CCCCCHHHHHCCCCCCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHCCCCEEE
CHPGEKHDSQIPE
ECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3536912; 3520491; 8041620; 9278503 [H]