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The map label for this gene is gpsA [H]

Identifier: 29144099

GI number: 29144099

Start: 3938599

End: 3939618

Strand: Direct

Name: gpsA [H]

Synonym: t3819

Alternate gene names: 29144099

Gene position: 3938599-3939618 (Clockwise)

Preceding gene: 29144098

Following gene: 29144100

Centisome position: 82.19

GC content: 57.55

Gene sequence:

>1020_bases
ATGAACCAAAGTAATGCGTCAATGACAGTCATCGGTGCCGGCTCGTACGGCACCGCTCTCGCCATCACTCTGGCGAGAAA
CGGCCACCAGGTTGTCCTGTGGGGCCACGACCCAAAACATATCGCGACCCTGGAGCACGATCGCTGCAACGTCGCGTTCC
TTCCCGATGTGCCTTTTCCCGATACGTTACACCTGGAAAGCGACTTAGCAACCGCGCTGGCGGCCAGTCGTAACATTCTG
GTGGTGGTGCCAAGCCATGTTTTCAGCGACGTGCTGCGGCAGATTAAACCGCTGATGCGTCCGGATGCGCGTCTGGTATG
GGCGACCAAAGGCCTGGAAGCGGAAACGGGGCGCCTGTTGCAGGATGTCGCTCGCGAGGCGTTAGGCGATCAAATCCCGC
TGGCGGTGATTTCCGGTCCGACGTTCGCTAAAGAGCTGGCGGCGGGTTTGCCGACGGCAATCTCGCTAGCCTCAACCGAT
GAGACCTTTGCCGACGATCTCCAGCAACTGTTGCACTGCGGAAAAAGTTTTCGCGTCTATATCAATGCGGATTTTATCGG
CGTGCAGCTTGGCGGCGCGGTGAAAAACGTGATTGCGATTGGCGCGGGGATGTCTGACGGCATCGGCTTCGGCGCGAACG
CCCGCACGGCGCTAATCACGCGTGGACTGACCGAAATGTCGCGGCTTGGCGCAGCGCTTGGTGCCGATCCCGCCACCTTT
ATGGGGATGGCGGGTTTAGGCGATCTGGTGCTGACCTGTACCGACAACCAGTCGCGCAACCGTCGTTTTGGCATGATGCT
TGGCCAGGGCATGGACGTTAAAGGCGCGCAGGATAAGATTGGCCAGGTGGTCGAAGGCTATCGCAATACGAAAGAAGTTC
GTGAATTGGCGCACCGTTTTGGTGTTGAAATGCCAATAACCGAGGAAATTTATCAAGTATTGTATTGCGGAAAAAACGCG
CGCGAGGCAGCATTAACGTTATTAGGTCGCGCCCGCAAGGAAGAGCTGAGTCGCCACTAG

Upstream 100 bases:

>100_bases
TCCCGCAACTGAACCTTGCGCCGGTCAACTTTGATGCGCTGTTCATGAACTATTTGCAGCAGCAGGCTGGCGAAGGTACT
GAAGAACATCAGGATGCCTG

Downstream 100 bases:

>100_bases
CCGTAAGGAACTGTTTGCATAAACGACCCAACCCGCACAGAACGGGTTGGTCGTTTTCTGCCCGTCTGGAGTAAGCCATG
CCGTGTGAAGAACTGGAAAT

Product: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NAD(P)H-dependent glycerol-3-phosphate dehydrogenase [H]

Number of amino acids: Translated: 339; Mature: 339

Protein sequence:

>339_residues
MNQSNASMTVIGAGSYGTALAITLARNGHQVVLWGHDPKHIATLEHDRCNVAFLPDVPFPDTLHLESDLATALAASRNIL
VVVPSHVFSDVLRQIKPLMRPDARLVWATKGLEAETGRLLQDVAREALGDQIPLAVISGPTFAKELAAGLPTAISLASTD
ETFADDLQQLLHCGKSFRVYINADFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLTEMSRLGAALGADPATF
MGMAGLGDLVLTCTDNQSRNRRFGMMLGQGMDVKGAQDKIGQVVEGYRNTKEVRELAHRFGVEMPITEEIYQVLYCGKNA
REAALTLLGRARKEELSRH

Sequences:

>Translated_339_residues
MNQSNASMTVIGAGSYGTALAITLARNGHQVVLWGHDPKHIATLEHDRCNVAFLPDVPFPDTLHLESDLATALAASRNIL
VVVPSHVFSDVLRQIKPLMRPDARLVWATKGLEAETGRLLQDVAREALGDQIPLAVISGPTFAKELAAGLPTAISLASTD
ETFADDLQQLLHCGKSFRVYINADFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLTEMSRLGAALGADPATF
MGMAGLGDLVLTCTDNQSRNRRFGMMLGQGMDVKGAQDKIGQVVEGYRNTKEVRELAHRFGVEMPITEEIYQVLYCGKNA
REAALTLLGRARKEELSRH
>Mature_339_residues
MNQSNASMTVIGAGSYGTALAITLARNGHQVVLWGHDPKHIATLEHDRCNVAFLPDVPFPDTLHLESDLATALAASRNIL
VVVPSHVFSDVLRQIKPLMRPDARLVWATKGLEAETGRLLQDVAREALGDQIPLAVISGPTFAKELAAGLPTAISLASTD
ETFADDLQQLLHCGKSFRVYINADFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLTEMSRLGAALGADPATF
MGMAGLGDLVLTCTDNQSRNRRFGMMLGQGMDVKGAQDKIGQVVEGYRNTKEVRELAHRFGVEMPITEEIYQVLYCGKNA
REAALTLLGRARKEELSRH

Specific function: De novo phospholipid biosynthesis; glycerol-3 phosphate formation. [C]

COG id: COG0240

COG function: function code C; Glycerol-3-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD-dependent glycerol-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI33695088, Length=343, Percent_Identity=26.8221574344023, Blast_Score=118, Evalue=6e-27,
Organism=Homo sapiens, GI24307999, Length=338, Percent_Identity=26.0355029585799, Blast_Score=108, Evalue=5e-24,
Organism=Escherichia coli, GI1790037, Length=339, Percent_Identity=94.9852507374631, Blast_Score=660, Evalue=0.0,
Organism=Caenorhabditis elegans, GI32564399, Length=361, Percent_Identity=24.6537396121884, Blast_Score=97, Evalue=9e-21,
Organism=Caenorhabditis elegans, GI193210136, Length=370, Percent_Identity=23.7837837837838, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI32564403, Length=370, Percent_Identity=23.7837837837838, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI17507425, Length=336, Percent_Identity=22.9166666666667, Blast_Score=92, Evalue=3e-19,
Organism=Caenorhabditis elegans, GI193210134, Length=229, Percent_Identity=27.5109170305677, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6324513, Length=342, Percent_Identity=26.3157894736842, Blast_Score=107, Evalue=2e-24,
Organism=Saccharomyces cerevisiae, GI6320181, Length=342, Percent_Identity=28.3625730994152, Blast_Score=107, Evalue=4e-24,
Organism=Drosophila melanogaster, GI17136204, Length=331, Percent_Identity=25.9818731117825, Blast_Score=99, Evalue=6e-21,
Organism=Drosophila melanogaster, GI17136202, Length=331, Percent_Identity=25.9818731117825, Blast_Score=98, Evalue=6e-21,
Organism=Drosophila melanogaster, GI17136200, Length=331, Percent_Identity=25.9818731117825, Blast_Score=98, Evalue=8e-21,
Organism=Drosophila melanogaster, GI22026922, Length=273, Percent_Identity=24.1758241758242, Blast_Score=85, Evalue=8e-17,
Organism=Drosophila melanogaster, GI45551945, Length=238, Percent_Identity=26.890756302521, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI281362270, Length=238, Percent_Identity=26.890756302521, Blast_Score=74, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24648969, Length=183, Percent_Identity=28.4153005464481, Blast_Score=69, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013328
- InterPro:   IPR006168
- InterPro:   IPR006109
- InterPro:   IPR011128
- InterPro:   IPR016040 [H]

Pfam domain/function: PF07479 NAD_Gly3P_dh_C; PF01210 NAD_Gly3P_dh_N [H]

EC number: =1.1.1.94 [H]

Molecular weight: Translated: 36343; Mature: 36343

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00957 NAD_G3PDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQSNASMTVIGAGSYGTALAITLARNGHQVVLWGHDPKHIATLEHDRCNVAFLPDVPFP
CCCCCCCEEEEECCCCCCEEEEEEECCCCEEEEECCCCCEEEEECCCCCCEEEECCCCCC
DTLHLESDLATALAASRNILVVVPSHVFSDVLRQIKPLMRPDARLVWATKGLEAETGRLL
CCEECHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHH
QDVAREALGDQIPLAVISGPTFAKELAAGLPTAISLASTDETFADDLQQLLHCGKSFRVY
HHHHHHHCCCCCCEEEECCCHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHCCCCEEEE
INADFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLTEMSRLGAALGADPATF
EEEEEEEEEECHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHH
MGMAGLGDLVLTCTDNQSRNRRFGMMLGQGMDVKGAQDKIGQVVEGYRNTKEVRELAHRF
HHHCCCCCEEEEECCCCCCCCEEHHHHCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHC
GVEMPITEEIYQVLYCGKNAREAALTLLGRARKEELSRH
CCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNQSNASMTVIGAGSYGTALAITLARNGHQVVLWGHDPKHIATLEHDRCNVAFLPDVPFP
CCCCCCCEEEEECCCCCCEEEEEEECCCCEEEEECCCCCEEEEECCCCCCEEEECCCCCC
DTLHLESDLATALAASRNILVVVPSHVFSDVLRQIKPLMRPDARLVWATKGLEAETGRLL
CCEECHHHHHHHHHCCCCEEEEECHHHHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHH
QDVAREALGDQIPLAVISGPTFAKELAAGLPTAISLASTDETFADDLQQLLHCGKSFRVY
HHHHHHHCCCCCCEEEECCCHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHCCCCEEEE
INADFIGVQLGGAVKNVIAIGAGMSDGIGFGANARTALITRGLTEMSRLGAALGADPATF
EEEEEEEEEECHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHH
MGMAGLGDLVLTCTDNQSRNRRFGMMLGQGMDVKGAQDKIGQVVEGYRNTKEVRELAHRF
HHHCCCCCEEEEECCCCCCCCEEHHHHCCCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHC
GVEMPITEEIYQVLYCGKNAREAALTLLGRARKEELSRH
CCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA