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The map label for this gene is mgtC [H]

Identifier: 29144042

GI number: 29144042

Start: 3869103

End: 3869798

Strand: Direct

Name: mgtC [H]

Synonym: t3754

Alternate gene names: 29144042

Gene position: 3869103-3869798 (Clockwise)

Preceding gene: 29144040

Following gene: 29144043

Centisome position: 80.74

GC content: 49.86

Gene sequence:

>696_bases
ATGGAGGAACGTATGTTAATGTTTCCTTATATTTTAAATTTACTGGCCGCTATGCTGTTGGGCGCGCTGATTGGCGCGGA
AAGACAATGGCGTCAACGTATGGCGGGATTACGCACTAATGCGCTGGTGGCGACAGGCGCCGCCGTTTTTATTCTGAGCT
CCATGACGACATCGCCAGACAGCCCCGGGAGAATTGCGGCGCAGATTGTCTCTGGTATTGGCTTTCTGGGGGCGGGCGTC
ATCATGCGCGAAGGGATGAATGTGCGCGGACTGAACACTGCGGCAACGCTATGGTGTTCGGCGGGCATCGGCGTGTTATG
CGGCTTAGGGCAGTTCAAAAATGCACTGGCGGCGACGATCATTATTCTTTGTGCCAATATTTTATTGCGTGAAGCGGCGC
AGCGTATAAATCAACTCCCGGTATCCGCCGAGGCAGAAAAACGTTATATCCTGAAAGTAACCTGTAATAAAGAAGATGAG
AGCGCGGTTCGTCAGTGGTTACTGAATATCGTAAAAGAGGCCGCGATCTGTTTACAAGGGTTAGGTTCGGTCCCCGCTCA
GGAACAGGGCTATAAAGAAATTCGTGCCGAGCTCGTGGGTCATGCTGATTATCGTAAAACGCGAGAACTGATTATATCCA
GAATAGGTGATAACGATAATATCACCGCAATTCACTGGAGCATTGATAGTCAATAA

Upstream 100 bases:

>100_bases
AACACGCTTTATTTCCTCCGCCGTTAACACGACGCTAATTGCCTCAGGGCAGAAATTTGTCGTGTGCTAAATATAGCACG
TACTTATTCTTCCAGAAAAA

Downstream 100 bases:

>100_bases
TAGTTTTTTATTCAATTGCAACATTACGCCAGGCGTATAAGGAGGGAATGATGGATATTCCCGAGTCGATAAAATAAAAC
CCACTCAAAATAGTGAGTAA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MEERMLMFPYILNLLAAMLLGALIGAERQWRQRMAGLRTNALVATGAAVFILSSMTTSPDSPGRIAAQIVSGIGFLGAGV
IMREGMNVRGLNTAATLWCSAGIGVLCGLGQFKNALAATIIILCANILLREAAQRINQLPVSAEAEKRYILKVTCNKEDE
SAVRQWLLNIVKEAAICLQGLGSVPAQEQGYKEIRAELVGHADYRKTRELIISRIGDNDNITAIHWSIDSQ

Sequences:

>Translated_231_residues
MEERMLMFPYILNLLAAMLLGALIGAERQWRQRMAGLRTNALVATGAAVFILSSMTTSPDSPGRIAAQIVSGIGFLGAGV
IMREGMNVRGLNTAATLWCSAGIGVLCGLGQFKNALAATIIILCANILLREAAQRINQLPVSAEAEKRYILKVTCNKEDE
SAVRQWLLNIVKEAAICLQGLGSVPAQEQGYKEIRAELVGHADYRKTRELIISRIGDNDNITAIHWSIDSQ
>Mature_231_residues
MEERMLMFPYILNLLAAMLLGALIGAERQWRQRMAGLRTNALVATGAAVFILSSMTTSPDSPGRIAAQIVSGIGFLGAGV
IMREGMNVRGLNTAATLWCSAGIGVLCGLGQFKNALAATIIILCANILLREAAQRINQLPVSAEAEKRYILKVTCNKEDE
SAVRQWLLNIVKEAAICLQGLGSVPAQEQGYKEIRAELVGHADYRKTRELIISRIGDNDNITAIHWSIDSQ

Specific function: Virulence factor required for growth in low Mg(2+) medium and for intramacrophage survival. May be involved in regulating membrane potential by activating Na(+)/K(+)-ATPase [H]

COG id: COG1285

COG function: function code S; Uncharacterized membrane protein

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MgtC/SapB family [H]

Homologues:

Organism=Escherichia coli, GI1789924, Length=163, Percent_Identity=33.7423312883436, Blast_Score=90, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003416 [H]

Pfam domain/function: PF02308 MgtC [H]

EC number: NA

Molecular weight: Translated: 25066; Mature: 25066

Theoretical pI: Translated: 8.48; Mature: 8.48

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEERMLMFPYILNLLAAMLLGALIGAERQWRQRMAGLRTNALVATGAAVFILSSMTTSPD
CCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCC
SPGRIAAQIVSGIGFLGAGVIMREGMNVRGLNTAATLWCSAGIGVLCGLGQFKNALAATI
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHCCHHHHHHHHHHH
IILCANILLREAAQRINQLPVSAEAEKRYILKVTCNKEDESAVRQWLLNIVKEAAICLQG
HHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
LGSVPAQEQGYKEIRAELVGHADYRKTRELIISRIGDNDNITAIHWSIDSQ
CCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCC
>Mature Secondary Structure
MEERMLMFPYILNLLAAMLLGALIGAERQWRQRMAGLRTNALVATGAAVFILSSMTTSPD
CCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCCCCC
SPGRIAAQIVSGIGFLGAGVIMREGMNVRGLNTAATLWCSAGIGVLCGLGQFKNALAATI
CCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCHHHHHCCHHHHHHHHHHH
IILCANILLREAAQRINQLPVSAEAEKRYILKVTCNKEDESAVRQWLLNIVKEAAICLQG
HHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHHHHHHH
LGSVPAQEQGYKEIRAELVGHADYRKTRELIISRIGDNDNITAIHWSIDSQ
CCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA