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The map label for this gene is mngR [H]

Identifier: 29144024

GI number: 29144024

Start: 3849104

End: 3849847

Strand: Direct

Name: mngR [H]

Synonym: t3733

Alternate gene names: 29144024

Gene position: 3849104-3849847 (Clockwise)

Preceding gene: 29144023

Following gene: 29144025

Centisome position: 80.32

GC content: 40.99

Gene sequence:

>744_bases
ATGAAAACATTGAGTAAAAGTTCACACATCCCACTGTATCAACAGGTTGTGGAGTGGATAAGGGAAAGTATTTATAGCGG
AGAATTGGTTGAGGATGACCGGATACCTTCAGAGTTTCAAATCATGGATATGCTGGAGGTGAGTCGCGGTACCGTTAAAA
AAGCGGTTGACCAACTTGTCCGGGAAGGTGTTCTTGTGCAAGTGCAGGGTAAAGGAACTTTCGTAAAGAAGGAAAATGTT
GCTTACCCACTGGGTGAAGGTTTGCTCTCCTTTGCTGAAGCCTTAGCCAGCCAGAAGATAAACTTCACAACCAGCGTCAT
AACCTCCCGACTGGAACCCGCTAACCGCTTTGTAGCAGAGAAACTGAGTATCAAACCGGGACAAGATGTTTTATTTCTTA
AACGCCTTCGTTGTATTGGCGATGAAAAAGTCATGTTGATTGAAAATCGTATCAACATTGATCTCTGCCCCGGTATTATT
GATGTAGATTTTACCAGGGAGAATTTATTTTCAGCAATAGAAAGATTATCTGATAAGAAAATAAGTTTTTCTGAAAGCCG
TTACGCAGCTAAATTAATTGGTAATGAGCGAGGCCATTATCTTGATATTGGTGAAGACGCACCTGTTTTGCATTTGGAAC
AGTTGGTATTTTTCTCTAGAGGATTGGCCATTGATTTTGGTAACGTCTGGTTAAAAGGTAATAAATATTATCTTGGCACT
ATTTTACAGCGCCTGGATGCCTGA

Upstream 100 bases:

>100_bases
TGTGACTCCTTGCCATACCTCCTGTCTCAAAATTTCTTATCATAAACTCGAAGTTGTACATGATTGTCTATAGACAACTC
TAAATGTTTAGGCGCGCACT

Downstream 100 bases:

>100_bases
CTAGCAAAGAGGAATCTATGCAGGATATTCATTTTCGCCGTCATTATGTTCGCCACCTCCCTAAAGAGGTGAGTCAGAAT
GACATAATCAAGGCTCTTGC

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: Fatty acyl-responsive regulator; Protein P30 [H]

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MKTLSKSSHIPLYQQVVEWIRESIYSGELVEDDRIPSEFQIMDMLEVSRGTVKKAVDQLVREGVLVQVQGKGTFVKKENV
AYPLGEGLLSFAEALASQKINFTTSVITSRLEPANRFVAEKLSIKPGQDVLFLKRLRCIGDEKVMLIENRINIDLCPGII
DVDFTRENLFSAIERLSDKKISFSESRYAAKLIGNERGHYLDIGEDAPVLHLEQLVFFSRGLAIDFGNVWLKGNKYYLGT
ILQRLDA

Sequences:

>Translated_247_residues
MKTLSKSSHIPLYQQVVEWIRESIYSGELVEDDRIPSEFQIMDMLEVSRGTVKKAVDQLVREGVLVQVQGKGTFVKKENV
AYPLGEGLLSFAEALASQKINFTTSVITSRLEPANRFVAEKLSIKPGQDVLFLKRLRCIGDEKVMLIENRINIDLCPGII
DVDFTRENLFSAIERLSDKKISFSESRYAAKLIGNERGHYLDIGEDAPVLHLEQLVFFSRGLAIDFGNVWLKGNKYYLGT
ILQRLDA
>Mature_247_residues
MKTLSKSSHIPLYQQVVEWIRESIYSGELVEDDRIPSEFQIMDMLEVSRGTVKKAVDQLVREGVLVQVQGKGTFVKKENV
AYPLGEGLLSFAEALASQKINFTTSVITSRLEPANRFVAEKLSIKPGQDVLFLKRLRCIGDEKVMLIENRINIDLCPGII
DVDFTRENLFSAIERLSDKKISFSESRYAAKLIGNERGHYLDIGEDAPVLHLEQLVFFSRGLAIDFGNVWLKGNKYYLGT
ILQRLDA

Specific function: Represses mngA and mngB. Regulates its own expression [H]

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786950, Length=236, Percent_Identity=29.2372881355932, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1790540, Length=185, Percent_Identity=29.7297297297297, Blast_Score=71, Evalue=6e-14,
Organism=Escherichia coli, GI1790118, Length=235, Percent_Identity=22.1276595744681, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1788418, Length=231, Percent_Identity=25.974025974026, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI87082252, Length=246, Percent_Identity=25.2032520325203, Blast_Score=64, Evalue=7e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 27943; Mature: 27943

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTLSKSSHIPLYQQVVEWIRESIYSGELVEDDRIPSEFQIMDMLEVSRGTVKKAVDQLV
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHH
REGVLVQVQGKGTFVKKENVAYPLGEGLLSFAEALASQKINFTTSVITSRLEPANRFVAE
HCCEEEEEECCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHH
KLSIKPGQDVLFLKRLRCIGDEKVMLIENRINIDLCPGIIDVDFTRENLFSAIERLSDKK
HHCCCCCCHHHHHHHHHHCCCCEEEEEECCCCEEECCCEEEECCCHHHHHHHHHHHCCCC
ISFSESRYAAKLIGNERGHYLDIGEDAPVLHLEQLVFFSRGLAIDFGNVWLKGNKYYLGT
CCCCHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHCCCEEEECCEEEECCCCHHHH
ILQRLDA
HHHHHCC
>Mature Secondary Structure
MKTLSKSSHIPLYQQVVEWIRESIYSGELVEDDRIPSEFQIMDMLEVSRGTVKKAVDQLV
CCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHH
REGVLVQVQGKGTFVKKENVAYPLGEGLLSFAEALASQKINFTTSVITSRLEPANRFVAE
HCCEEEEEECCCEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCHHHHHHHH
KLSIKPGQDVLFLKRLRCIGDEKVMLIENRINIDLCPGIIDVDFTRENLFSAIERLSDKK
HHCCCCCCHHHHHHHHHHCCCCEEEEEECCCCEEECCCEEEECCCHHHHHHHHHHHCCCC
ISFSESRYAAKLIGNERGHYLDIGEDAPVLHLEQLVFFSRGLAIDFGNVWLKGNKYYLGT
CCCCHHHHHHHHHCCCCCCEEECCCCCCHHHHHHHHHHHCCCEEEECCEEEECCCCHHHH
ILQRLDA
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2548486; 9278503; 9063979; 8905232; 7805834 [H]