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The map label for this gene is dsdC [H]

Identifier: 29144009

GI number: 29144009

Start: 3831346

End: 3832269

Strand: Direct

Name: dsdC [H]

Synonym: t3717

Alternate gene names: 29144009

Gene position: 3831346-3832269 (Clockwise)

Preceding gene: 29144006

Following gene: 29144010

Centisome position: 79.95

GC content: 52.81

Gene sequence:

>924_bases
ATGGAACCCCTTCGCGATACCCGAAACCGCTTACTCAACGGCTGGCAGTTATCCAAACTCTATACTTTTGAAGTCGCGGC
CAGACACCAGTCCTTTGCTCTGGCGGCAGATGAGCTGTCGTTAAGCCCCAGTGCGGTAAGCCATCGTATCAATCAACTGG
AAGCCGAGTTGGGAATCCAGCTATTTGTCCGCTCTCACCGTAAAGTGGAGCTTACCCATGAAGGCAAACGGGTATTCTGG
GCGCTGAAATCGTCGCTGGATACGTTGAATCAGGAAATCCTCGATATCAAAAATCAGGAACTGTCCGGCACGTTGACCGT
GTATTCACGCCCCTCTATCGCCCAGTGCTGGCTGGTGCCCGCGTTGGGGGACTTTACCCGTCGCTATCCGTCAATTTCTC
TCACTATGCTGACCGGCAACGATAACGTTAACCTACAGCGTGCCGGCATTGACCTGGCTATCTATTTTGACGATGCGCCG
TCGGCGCAGCTCACGCACCATTTTTTAATGGATGAGGCGATTTTGCCCGTTTGCAGCCCGGATTACGCCCGTCGTTTCGC
CTTGCAGGACAACCTGAATAACCTGCGGCACTGTACGCTCTTACACGACAGACAGGCGTGGAGTAACGATTCTGGCACCG
ATGAGTGGCACAGTTGGGCGCAGCATTTTGCGGTAAATTTGCCGGATTCATCCGGCATTGGCTTCGATCGTTCTGATTTA
GCGGTGATTGCCGCGATGAACCATATTGGCGTGGCGATGGGACGTAAACGACTGGTGCAAAAGCGTCTCGACAGCAGTGA
ACTGATTGCGCCTTTTGGTGACATGAGACTGAAATGTCATCAGCATTATTATGTCACCACTCTGCCTGGCAGGCAGTGGC
CGAAAATCGAGGCATTTATTCGCTGGTTGCAGGAACAGGTGTGA

Upstream 100 bases:

>100_bases
CCTTTATTTTGCGATATGGTTCATTTTACTTCATCTATGTGCGGATTTTTTCAGCGCGTTTTTTTACACTTCGGGAAATT
AAAAGATGACTGAGGTTGCC

Downstream 100 bases:

>100_bases
AGATTTATTACGCTTTGCCGCTACACCTGCCGGGAGTGAATATGCTAAATACGTGCTATCACCGTGGTAAAAATTTTAGG
GGGCGTCGTGTTTAAACCGC

Product: DNA-binding transcriptional regulator DsdC

Products: NA

Alternate protein names: D-serine deaminase activator [H]

Number of amino acids: Translated: 307; Mature: 307

Protein sequence:

>307_residues
MEPLRDTRNRLLNGWQLSKLYTFEVAARHQSFALAADELSLSPSAVSHRINQLEAELGIQLFVRSHRKVELTHEGKRVFW
ALKSSLDTLNQEILDIKNQELSGTLTVYSRPSIAQCWLVPALGDFTRRYPSISLTMLTGNDNVNLQRAGIDLAIYFDDAP
SAQLTHHFLMDEAILPVCSPDYARRFALQDNLNNLRHCTLLHDRQAWSNDSGTDEWHSWAQHFAVNLPDSSGIGFDRSDL
AVIAAMNHIGVAMGRKRLVQKRLDSSELIAPFGDMRLKCHQHYYVTTLPGRQWPKIEAFIRWLQEQV

Sequences:

>Translated_307_residues
MEPLRDTRNRLLNGWQLSKLYTFEVAARHQSFALAADELSLSPSAVSHRINQLEAELGIQLFVRSHRKVELTHEGKRVFW
ALKSSLDTLNQEILDIKNQELSGTLTVYSRPSIAQCWLVPALGDFTRRYPSISLTMLTGNDNVNLQRAGIDLAIYFDDAP
SAQLTHHFLMDEAILPVCSPDYARRFALQDNLNNLRHCTLLHDRQAWSNDSGTDEWHSWAQHFAVNLPDSSGIGFDRSDL
AVIAAMNHIGVAMGRKRLVQKRLDSSELIAPFGDMRLKCHQHYYVTTLPGRQWPKIEAFIRWLQEQV
>Mature_307_residues
MEPLRDTRNRLLNGWQLSKLYTFEVAARHQSFALAADELSLSPSAVSHRINQLEAELGIQLFVRSHRKVELTHEGKRVFW
ALKSSLDTLNQEILDIKNQELSGTLTVYSRPSIAQCWLVPALGDFTRRYPSISLTMLTGNDNVNLQRAGIDLAIYFDDAP
SAQLTHHFLMDEAILPVCSPDYARRFALQDNLNNLRHCTLLHDRQAWSNDSGTDEWHSWAQHFAVNLPDSSGIGFDRSDL
AVIAAMNHIGVAMGRKRLVQKRLDSSELIAPFGDMRLKCHQHYYVTTLPGRQWPKIEAFIRWLQEQV

Specific function: Regulates the expression of the dsd operon for D-serine deaminase (dsdA) [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788706, Length=307, Percent_Identity=90.5537459283388, Blast_Score=587, Evalue=1e-169,
Organism=Escherichia coli, GI1786448, Length=297, Percent_Identity=32.3232323232323, Blast_Score=143, Evalue=1e-35,
Organism=Escherichia coli, GI1789173, Length=288, Percent_Identity=30.9027777777778, Blast_Score=133, Evalue=2e-32,
Organism=Escherichia coli, GI1786401, Length=296, Percent_Identity=25.3378378378378, Blast_Score=90, Evalue=2e-19,
Organism=Escherichia coli, GI1787128, Length=285, Percent_Identity=28.0701754385965, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI145693193, Length=177, Percent_Identity=31.0734463276836, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI145693105, Length=172, Percent_Identity=26.7441860465116, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1788748, Length=181, Percent_Identity=28.7292817679558, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI87081978, Length=193, Percent_Identity=29.5336787564767, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1789440, Length=203, Percent_Identity=27.0935960591133, Blast_Score=68, Evalue=6e-13,
Organism=Escherichia coli, GI1790208, Length=143, Percent_Identity=32.1678321678322, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1787589, Length=187, Percent_Identity=28.8770053475936, Blast_Score=65, Evalue=6e-12,
Organism=Escherichia coli, GI157672245, Length=165, Percent_Identity=31.5151515151515, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011781
- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35058; Mature: 35058

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEPLRDTRNRLLNGWQLSKLYTFEVAARHQSFALAADELSLSPSAVSHRINQLEAELGIQ
CCCHHHHHHHHCCCEEEEEEEEEEEHHCCCCEEEEHHHCCCCHHHHHHHHHHHHHHHHHH
LFVRSHRKVELTHEGKRVFWALKSSLDTLNQEILDIKNQELSGTLTVYSRPSIAQCWLVP
EEEECCCEEEEEECCCEEEHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHEEEEH
ALGDFTRRYPSISLTMLTGNDNVNLQRAGIDLAIYFDDAPSAQLTHHFLMDEAILPVCSP
HHHHHHHHCCCEEEEEEECCCCCEEEECCEEEEEEECCCCCHHHHHHHHHHHHCCCCCCH
DYARRFALQDNLNNLRHCTLLHDRQAWSNDSGTDEWHSWAQHFAVNLPDSSGIGFDRSDL
HHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHEEEECCCCCCCCCCCCCC
AVIAAMNHIGVAMGRKRLVQKRLDSSELIAPFGDMRLKCHQHYYVTTLPGRQWPKIEAFI
EEEEHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCEEEEECEEEEEECCCCCCCHHHHHH
RWLQEQV
HHHHHCC
>Mature Secondary Structure
MEPLRDTRNRLLNGWQLSKLYTFEVAARHQSFALAADELSLSPSAVSHRINQLEAELGIQ
CCCHHHHHHHHCCCEEEEEEEEEEEHHCCCCEEEEHHHCCCCHHHHHHHHHHHHHHHHHH
LFVRSHRKVELTHEGKRVFWALKSSLDTLNQEILDIKNQELSGTLTVYSRPSIAQCWLVP
EEEECCCEEEEEECCCEEEHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHEEEEH
ALGDFTRRYPSISLTMLTGNDNVNLQRAGIDLAIYFDDAPSAQLTHHFLMDEAILPVCSP
HHHHHHHHCCCEEEEEEECCCCCEEEECCEEEEEEECCCCCHHHHHHHHHHHHCCCCCCH
DYARRFALQDNLNNLRHCTLLHDRQAWSNDSGTDEWHSWAQHFAVNLPDSSGIGFDRSDL
HHHHHHHHHHCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHEEEECCCCCCCCCCCCCC
AVIAAMNHIGVAMGRKRLVQKRLDSSELIAPFGDMRLKCHQHYYVTTLPGRQWPKIEAFI
EEEEHHHHHHHHHHHHHHHHHHCCCCCEECCCCCCEEEEECEEEEEECCCCCCCHHHHHH
RWLQEQV
HHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7592420; 9205837; 9278503 [H]