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The map label for this gene is atpD [H]

Identifier: 29143949

GI number: 29143949

Start: 3759219

End: 3760601

Strand: Direct

Name: atpD [H]

Synonym: t3654

Alternate gene names: 29143949

Gene position: 3759219-3760601 (Clockwise)

Preceding gene: 29143948

Following gene: 29143950

Centisome position: 78.45

GC content: 55.1

Gene sequence:

>1383_bases
ATGGCTACTGGAAAGATTGTCCAGGTAATCGGCGCCGTGGTAGACGTCGAGTTCCCTCAGGATGCCGTACCACGCGTGTA
CGATGCCCTTGAGGTGCAGAATGGTAATGAGAAGCTGGTGCTGGAAGTTCAGCAGCAGCTTGGCGGCGGTATCGTGCGTA
CCATCGCGATGGGGTCTTCTGACGGTCTGCGTCGCGGTCTGGATGTAAAAGATCTCGAACACCCGATCGAAGTCCCGGTA
GGTAAAGCTACGCTGGGTCGTATCATGAACGTCCTGGGCGAACCGGTCGACATGAAAGGCGAGATCGGCGAAGAAGAGCG
TTGGGCGATTCACCGCGCAGCGCCTTCCTACGAAGAGTTATCAAACTCTCAGGAACTGCTGGAAACCGGTATCAAAGTTA
TCGACCTGATGTGTCCGTTCGCGAAGGGCGGTAAAGTCGGTCTGTTCGGTGGTGCGGGTGTAGGTAAAACCGTAAACATG
ATGGAGCTTATCCGTAACATCGCGATCGAGCACTCCGGTTACTCTGTGTTTGCGGGCGTAGGTGAACGTACTCGTGAGGG
TAACGACTTCTACCATGAAATGACCGACTCCAACGTTATCGATAAAGTATCCCTGGTGTATGGCCAGATGAACGAGCCGC
CGGGAAACCGTCTGCGCGTTGCACTGACCGGCCTGACCATGGCGGAGAAATTCCGTGACGAAGGTCGTGACGTACTGCTG
TTCGTCGATAACATCTATCGTTACACCCTGGCCGGTACGGAAGTATCCGCACTGCTGGGTCGTATGCCTTCCGCGGTAGG
TTACCAGCCGACTCTGGCGGAAGAGATGGGCGTTCTGCAGGAACGTATCACCTCCACCAAGACCGGTTCTATCACCTCCG
TACAGGCGGTATACGTACCTGCGGATGACTTAACTGACCCGTCTCCAGCCACCACCTTTGCGCACTTAGATGCAACTGTG
GTACTGAGCCGTCAGATCGCATCCCTGGGTATCTACCCGGCCGTTGACCCGCTGGATTCCACCAGCCGTCAGCTGGATCC
GCTGGTTGTTGGTCAGGAACACTACGACACCGCGCGTGGCGTTCAGTCCATCCTGCAGCGTTATCAGGAACTGAAAGACA
TCATCGCCATCCTCGGTATGGATGAACTGTCTGAAGAAGATAAACTGGTGGTAGCTCGCGCGCGTAAGATCCAGCGCTTC
CTGTCCCAGCCGTTCTTCGTGGCGGAAGTATTTACCGGTTCTCCGGGCAAATACGTCTCCCTGAAAGACACCATCCGTGG
CTTTAAAGGCATCATGGAAGGCGAATACGATCACCTGCCGGAGCAGGCGTTCTACATGGTCGGTTCCATCGACGAAGCCG
TGGAAAAAGCCAAAAAACTTTAA

Upstream 100 bases:

>100_bases
TATACAACAAAGCTCGTCAGGCCAGCATTACTCAGGAACTCACCGAGATCGTCTCGGGGGCCGCCGCGGTTTAACCAGGT
TATTTCGTAGAGGATTTAAG

Downstream 100 bases:

>100_bases
CGCCTTAATCGGAGGGTGATATGGCAATGACTTACCACCTGGATGTCGTCAGCGCGGAGCAACAAATGTTCTCCGGTCTG
GTCGAGAAAATCCAGGTTAC

Product: F0F1 ATP synthase subunit beta

Products: NA

Alternate protein names: ATP synthase F1 sector subunit beta; F-ATPase subunit beta [H]

Number of amino acids: Translated: 460; Mature: 459

Protein sequence:

>460_residues
MATGKIVQVIGAVVDVEFPQDAVPRVYDALEVQNGNEKLVLEVQQQLGGGIVRTIAMGSSDGLRRGLDVKDLEHPIEVPV
GKATLGRIMNVLGEPVDMKGEIGEEERWAIHRAAPSYEELSNSQELLETGIKVIDLMCPFAKGGKVGLFGGAGVGKTVNM
MELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLL
FVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATV
VLSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDTARGVQSILQRYQELKDIIAILGMDELSEEDKLVVARARKIQRF
LSQPFFVAEVFTGSPGKYVSLKDTIRGFKGIMEGEYDHLPEQAFYMVGSIDEAVEKAKKL

Sequences:

>Translated_460_residues
MATGKIVQVIGAVVDVEFPQDAVPRVYDALEVQNGNEKLVLEVQQQLGGGIVRTIAMGSSDGLRRGLDVKDLEHPIEVPV
GKATLGRIMNVLGEPVDMKGEIGEEERWAIHRAAPSYEELSNSQELLETGIKVIDLMCPFAKGGKVGLFGGAGVGKTVNM
MELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLL
FVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATV
VLSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDTARGVQSILQRYQELKDIIAILGMDELSEEDKLVVARARKIQRF
LSQPFFVAEVFTGSPGKYVSLKDTIRGFKGIMEGEYDHLPEQAFYMVGSIDEAVEKAKKL
>Mature_459_residues
ATGKIVQVIGAVVDVEFPQDAVPRVYDALEVQNGNEKLVLEVQQQLGGGIVRTIAMGSSDGLRRGLDVKDLEHPIEVPVG
KATLGRIMNVLGEPVDMKGEIGEEERWAIHRAAPSYEELSNSQELLETGIKVIDLMCPFAKGGKVGLFGGAGVGKTVNMM
ELIRNIAIEHSGYSVFAGVGERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLLF
VDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVPADDLTDPSPATTFAHLDATVV
LSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDTARGVQSILQRYQELKDIIAILGMDELSEEDKLVVARARKIQRFL
SQPFFVAEVFTGSPGKYVSLKDTIRGFKGIMEGEYDHLPEQAFYMVGSIDEAVEKAKKL

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits [H]

COG id: COG0055

COG function: function code C; F0F1-type ATP synthase, beta subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI32189394, Length=466, Percent_Identity=71.244635193133, Blast_Score=657, Evalue=0.0,
Organism=Homo sapiens, GI19913424, Length=321, Percent_Identity=28.0373831775701, Blast_Score=117, Evalue=2e-26,
Organism=Homo sapiens, GI19913428, Length=356, Percent_Identity=24.438202247191, Blast_Score=102, Evalue=5e-22,
Organism=Homo sapiens, GI50345984, Length=303, Percent_Identity=25.0825082508251, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI4757810, Length=303, Percent_Identity=25.0825082508251, Blast_Score=101, Evalue=2e-21,
Organism=Homo sapiens, GI19913426, Length=356, Percent_Identity=23.876404494382, Blast_Score=100, Evalue=3e-21,
Organism=Escherichia coli, GI1790170, Length=460, Percent_Identity=99.5652173913043, Blast_Score=930, Evalue=0.0,
Organism=Escherichia coli, GI1788251, Length=317, Percent_Identity=29.6529968454259, Blast_Score=139, Evalue=6e-34,
Organism=Escherichia coli, GI1790172, Length=340, Percent_Identity=26.1764705882353, Blast_Score=112, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI25144756, Length=466, Percent_Identity=69.3133047210301, Blast_Score=644, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17565854, Length=321, Percent_Identity=28.9719626168224, Blast_Score=120, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17510931, Length=348, Percent_Identity=25.5747126436782, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17570191, Length=416, Percent_Identity=24.0384615384615, Blast_Score=103, Evalue=2e-22,
Organism=Caenorhabditis elegans, GI71988080, Length=303, Percent_Identity=25.4125412541254, Blast_Score=102, Evalue=3e-22,
Organism=Caenorhabditis elegans, GI71988063, Length=303, Percent_Identity=25.4125412541254, Blast_Score=102, Evalue=5e-22,
Organism=Caenorhabditis elegans, GI71988074, Length=303, Percent_Identity=23.7623762376238, Blast_Score=86, Evalue=5e-17,
Organism=Saccharomyces cerevisiae, GI6322581, Length=458, Percent_Identity=68.3406113537118, Blast_Score=628, Evalue=0.0,
Organism=Saccharomyces cerevisiae, GI6319603, Length=362, Percent_Identity=25.414364640884, Blast_Score=109, Evalue=1e-24,
Organism=Saccharomyces cerevisiae, GI6319370, Length=405, Percent_Identity=24.1975308641975, Blast_Score=100, Evalue=6e-22,
Organism=Saccharomyces cerevisiae, GI6320016, Length=233, Percent_Identity=27.4678111587983, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24638766, Length=465, Percent_Identity=69.8924731182796, Blast_Score=646, Evalue=0.0,
Organism=Drosophila melanogaster, GI28574560, Length=465, Percent_Identity=65.8064516129032, Blast_Score=597, Evalue=1e-171,
Organism=Drosophila melanogaster, GI20129479, Length=331, Percent_Identity=27.190332326284, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24583992, Length=321, Percent_Identity=28.0373831775701, Blast_Score=117, Evalue=2e-26,
Organism=Drosophila melanogaster, GI24583988, Length=321, Percent_Identity=27.4143302180685, Blast_Score=115, Evalue=6e-26,
Organism=Drosophila melanogaster, GI24583986, Length=321, Percent_Identity=27.4143302180685, Blast_Score=115, Evalue=6e-26,
Organism=Drosophila melanogaster, GI24583984, Length=321, Percent_Identity=27.4143302180685, Blast_Score=115, Evalue=6e-26,
Organism=Drosophila melanogaster, GI281361666, Length=348, Percent_Identity=24.4252873563218, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24646341, Length=348, Percent_Identity=24.4252873563218, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI17136796, Length=348, Percent_Identity=24.4252873563218, Blast_Score=102, Evalue=5e-22,
Organism=Drosophila melanogaster, GI24658560, Length=342, Percent_Identity=24.8538011695906, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24638768, Length=92, Percent_Identity=57.6086956521739, Blast_Score=97, Evalue=2e-20,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR003593
- InterPro:   IPR005722
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 50284; Mature: 50153

Theoretical pI: Translated: 4.63; Mature: 4.63

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATGKIVQVIGAVVDVEFPQDAVPRVYDALEVQNGNEKLVLEVQQQLGGGIVRTIAMGSS
CCCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEEHEEEHHHHCCCEEEEEECCCC
DGLRRGLDVKDLEHPIEVPVGKATLGRIMNVLGEPVDMKGEIGEEERWAIHRAAPSYEEL
CHHHCCCCHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCHHHH
SNSQELLETGIKVIDLMCPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGV
CCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEECC
GERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLL
CCCCCCCCHHHHHHCCCCHHHHHHHHHCCCCCCCCCEEEEEEECHHHHHHHHHCCCEEEE
FVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVP
EEECHHEEEECCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEC
ADDLTDPSPATTFAHLDATVVLSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDTARG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCEEECCHHHHHHHH
VQSILQRYQELKDIIAILGMDELSEEDKLVVARARKIQRFLSQPFFVAEVFTGSPGKYVS
HHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCEEE
LKDTIRGFKGIMEGEYDHLPEQAFYMVGSIDEAVEKAKKL
HHHHHHHHHHHHCCCHHCCCHHHHHHHCCHHHHHHHHHCC
>Mature Secondary Structure 
ATGKIVQVIGAVVDVEFPQDAVPRVYDALEVQNGNEKLVLEVQQQLGGGIVRTIAMGSS
CCHHHHHHHHHHHCCCCCCHHHHHHHHHHHCCCCCCEEHEEEHHHHCCCEEEEEECCCC
DGLRRGLDVKDLEHPIEVPVGKATLGRIMNVLGEPVDMKGEIGEEERWAIHRAAPSYEEL
CHHHCCCCHHHCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCCCCCHHHH
SNSQELLETGIKVIDLMCPFAKGGKVGLFGGAGVGKTVNMMELIRNIAIEHSGYSVFAGV
CCHHHHHHHHHHHHHHHCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHCCCCCEEEECC
GERTREGNDFYHEMTDSNVIDKVSLVYGQMNEPPGNRLRVALTGLTMAEKFRDEGRDVLL
CCCCCCCCHHHHHHCCCCHHHHHHHHHCCCCCCCCCEEEEEEECHHHHHHHHHCCCEEEE
FVDNIYRYTLAGTEVSALLGRMPSAVGYQPTLAEEMGVLQERITSTKTGSITSVQAVYVP
EEECHHEEEECCCHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEC
ADDLTDPSPATTFAHLDATVVLSRQIASLGIYPAVDPLDSTSRQLDPLVVGQEHYDTARG
CCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHCCCEEECCHHHHHHHH
VQSILQRYQELKDIIAILGMDELSEEDKLVVARARKIQRFLSQPFFVAEVFTGSPGKYVS
HHHHHHHHHHHHHHHHHHCCHHCCCCCHHHHHHHHHHHHHHCCCEEEEEEEECCCCCEEE
LKDTIRGFKGIMEGEYDHLPEQAFYMVGSIDEAVEKAKKL
HHHHHHHHHHHHCCCHHCCCHHHHHHHCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA