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The map label for this gene is mobA

Identifier: 29143925

GI number: 29143925

Start: 3728210

End: 3728794

Strand: Direct

Name: mobA

Synonym: t3626

Alternate gene names: 29143925

Gene position: 3728210-3728794 (Clockwise)

Preceding gene: 29143921

Following gene: 29143926

Centisome position: 77.8

GC content: 54.7

Gene sequence:

>585_bases
GTGAATCTGGATGAAGTAATAACCGGCGTGGTACTGGCAGGCGGTAAAGCCCGGCGGATGGGAGGTGCGGATAAAGGTCT
GCTTGAACTGGACGGGAAACCGCTCTGGCGACACGTTGCCGACGCGCTCGCGCCACAACTTGCTACGGTCGTAATTAGTG
CTAATCGCCATCTGGATATCTACCAGGCCAGCGGCCTGAAAGTCATTCCGGATTCAATCGCTGACTTTCCCGGTCCGCTG
GCGGGTATGCTTTCCGTTTTTCAGCAGGTAGCAGGCGACTGGTTTCTGTTTTGTCCCTGTGACAATCCTTGTATCCCCCA
CAACCTGGTCGATCGTTTAGCAGCGCATCGTCATGGCGCACCCGTGGTTTGGGTTCATGATGGAGAACGCGATCATCCAA
CGATCGCGTTGATTAATCGTGCCGTTGAGCCCCAGTTGACAGCTTATTTGCAAGCAGGCGAGCGGCGGGTAATGATTTTT
ATGCGCCAGGTAGGCGGACACGCCGTTGATTTCAGCGATTGTAAGGAGGCATTTGTGAACGTCAACACGCCGGAGGAACT
CGCGCAATGGCAAAAGAGACCATGA

Upstream 100 bases:

>100_bases
CAATGACTTCATTCAGGCGTTTACATTTCATAGCTGTGCTCCTTATTCTTGATACAGACACGGTAGCAGGGTCAATCCCA
CAATAAAAGAGGCGATATCG

Downstream 100 bases:

>100_bases
TACCGCTACTCGCCATTGCCGCATGGAGCGGCACGGGAAAAACAACACTGCTGAAAAAACTGATCCCAGCACTTTGTGCG
CACGGTATTCGGCCAGGGCT

Product: molybdopterin-guanine dinucleotide biosynthesis protein MobA

Products: molybdopterin guanine dinucleotide; pyrophosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 194; Mature: 194

Protein sequence:

>194_residues
MNLDEVITGVVLAGGKARRMGGADKGLLELDGKPLWRHVADALAPQLATVVISANRHLDIYQASGLKVIPDSIADFPGPL
AGMLSVFQQVAGDWFLFCPCDNPCIPHNLVDRLAAHRHGAPVVWVHDGERDHPTIALINRAVEPQLTAYLQAGERRVMIF
MRQVGGHAVDFSDCKEAFVNVNTPEELAQWQKRP

Sequences:

>Translated_194_residues
MNLDEVITGVVLAGGKARRMGGADKGLLELDGKPLWRHVADALAPQLATVVISANRHLDIYQASGLKVIPDSIADFPGPL
AGMLSVFQQVAGDWFLFCPCDNPCIPHNLVDRLAAHRHGAPVVWVHDGERDHPTIALINRAVEPQLTAYLQAGERRVMIF
MRQVGGHAVDFSDCKEAFVNVNTPEELAQWQKRP
>Mature_194_residues
MNLDEVITGVVLAGGKARRMGGADKGLLELDGKPLWRHVADALAPQLATVVISANRHLDIYQASGLKVIPDSIADFPGPL
AGMLSVFQQVAGDWFLFCPCDNPCIPHNLVDRLAAHRHGAPVVWVHDGERDHPTIALINRAVEPQLTAYLQAGERRVMIF
MRQVGGHAVDFSDCKEAFVNVNTPEELAQWQKRP

Specific function: Links a guanosine 5'-phosphate to molydopterin (MPT) forming molybdopterin guanine dinucleotide (MGD)

COG id: COG0746

COG function: function code H; Molybdopterin-guanine dinucleotide biosynthesis protein A

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mobA family

Homologues:

Organism=Escherichia coli, GI1790288, Length=193, Percent_Identity=77.2020725388601, Blast_Score=311, Evalue=2e-86,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MOBA_SALTI (Q8Z2R9)

Other databases:

- EMBL:   AL627280
- EMBL:   AE014613
- RefSeq:   NP_458054.1
- RefSeq:   NP_807267.1
- ProteinModelPortal:   Q8Z2R9
- SMR:   Q8Z2R9
- GeneID:   1068293
- GeneID:   1250133
- GenomeReviews:   AE014613_GR
- GenomeReviews:   AL513382_GR
- KEGG:   stt:t3626
- KEGG:   sty:STY3886
- HOGENOM:   HBG726756
- OMA:   SPQVDET
- ProtClustDB:   PRK00317
- BioCyc:   SENT209261:T3626-MONOMER
- BioCyc:   SENT220341:STY3886-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00316
- InterPro:   IPR013482
- TIGRFAMs:   TIGR02665

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 21257; Mature: 21257

Theoretical pI: Translated: 6.50; Mature: 6.50

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLDEVITGVVLAGGKARRMGGADKGLLELDGKPLWRHVADALAPQLATVVISANRHLDI
CCHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHEEEECCCCEEE
YQASGLKVIPDSIADFPGPLAGMLSVFQQVAGDWFLFCPCDNPCIPHNLVDRLAAHRHGA
EECCCCEECCHHHHCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHCCCC
PVVWVHDGERDHPTIALINRAVEPQLTAYLQAGERRVMIFMRQVGGHAVDFSDCKEAFVN
CEEEEECCCCCCCHHEEHHHCCCHHHHHHHHCCCCEEEHHHHHHCCCCCCHHHHHHHHCC
VNTPEELAQWQKRP
CCCHHHHHHHCCCC
>Mature Secondary Structure
MNLDEVITGVVLAGGKARRMGGADKGLLELDGKPLWRHVADALAPQLATVVISANRHLDI
CCHHHHHHHHHHCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHEEEECCCCEEE
YQASGLKVIPDSIADFPGPLAGMLSVFQQVAGDWFLFCPCDNPCIPHNLVDRLAAHRHGA
EECCCCEECCHHHHCCCCHHHHHHHHHHHHCCCEEEEECCCCCCCCHHHHHHHHHHCCCC
PVVWVHDGERDHPTIALINRAVEPQLTAYLQAGERRVMIFMRQVGGHAVDFSDCKEAFVN
CEEEEECCCCCCCHHEEHHHCCCHHHHHHHHCCCCEEEHHHHHHCCCCCCHHHHHHHHCC
VNTPEELAQWQKRP
CCCHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: molybdopterin; GTP [C]

Specific reaction: molybdopterin + GTP = molybdopterin guanine dinucleotide + pyrophosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504