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The map label for this gene is glnL [H]

Identifier: 29143914

GI number: 29143914

Start: 3715665

End: 3716714

Strand: Direct

Name: glnL [H]

Synonym: t3615

Alternate gene names: 29143914

Gene position: 3715665-3716714 (Clockwise)

Preceding gene: 29143913

Following gene: 29143915

Centisome position: 77.54

GC content: 57.14

Gene sequence:

>1050_bases
ATGGCAAGCGGCATACAGCCCGATGCTGGGCAGATCCTCAATTCGTTAATCAACAGCGTGCTGGTGGTCGACGACGCGCT
GGCAATCCATTACGCCAACCCTGCCGCGCAGCAGTTGCTCGCGCAAAGCTCACGCAAACTGTTCGGGACGCCGTTACCTG
AACTGTTGAGCTATTTTTCGTTAAACATTGACCTGATGCGCGAAAGTTTAGCGGCAGGACAAGGCTTTACCGATAACGAA
GTGACGCTGGTGATTGATAGTCGCTCGCATATTCTCTCTTTGACCGCCCAACGTCTGCCCGACGATTTTATACTGCTCGA
AATGGCGCCGATGGATAACCAGCGTCGTCTGAGTCAGGAGCAGTTGCAGCACGCGCAGCAAATCGCCGCCCGCGATCTGG
TGCGCGGTCTGGCGCACGAAATCAAAAATCCGCTCGGCGGCCTGCGCGGCGCGGCGCAGCTACTCAGCAAGGCGCTGCCC
GACCCGGCGCTAACGGAATATACCAAAGTCATCATTGAACAGGCCGACAGGCTACGCAACCTTGTCGATCGTTTGCTGGG
GCCGCAGCACCCGGGAATGCACATTACCGAGAGCATACATAAAGTCGCGGAGCGCGTGGTGGCGCTGGTGTCGATGGAAC
TGCCGGATAATGTCCGGCTTATCCGCGATTACGACCCCAGTCTGCCAGAACTGCCGCACGACCCGGAACAAATTGAGCAA
GTACTGCTGAATATTGTCCGCAATGCCTTGCAGGCGCTGGGGCCGGAAGGCGGCGAAATTACGCTGCGTACCCGTACCGC
CTTCCAGTTAACGCTGCATGGCGAACGCTATCGCCTGGCGGCGCGTATAGACGTTGAAGACAATGGGCCGGGCATTCCTC
CCCATTTACAGGATACGCTGTTCTACCCGATGGTCAGCGGTCGCGAAGGCGGCACCGGGCTTGGGTTATCTATCGCCCGC
AATCTTATCGATCAACACGCCGGCAAAATTGAATTTACCAGTTGGCCGGGGCATACCGAGTTTTCGGTTTACCTGCCGAT
TCGGAAATAG

Upstream 100 bases:

>100_bases
TGGGCTTTTTTCTCCACCAACAATCTGATCTCACGCGCTTTTTAGTGGTAAAAAGCTATAATGCACTAAAATGGTGCAAC
CTTTTCCAGGAGACTGCTGA

Downstream 100 bases:

>100_bases
AGGTGTTTATGCAACGAGGAATAGTCTGGGTCGTCGATGATGATAGTTCCATCCGTTGGGTGCTTGAACGTGCTCTCGCC
GGGGCAGGGTTGACCTGTAT

Product: nitrogen regulation protein NR(II)

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 349; Mature: 348

Protein sequence:

>349_residues
MASGIQPDAGQILNSLINSVLVVDDALAIHYANPAAQQLLAQSSRKLFGTPLPELLSYFSLNIDLMRESLAAGQGFTDNE
VTLVIDSRSHILSLTAQRLPDDFILLEMAPMDNQRRLSQEQLQHAQQIAARDLVRGLAHEIKNPLGGLRGAAQLLSKALP
DPALTEYTKVIIEQADRLRNLVDRLLGPQHPGMHITESIHKVAERVVALVSMELPDNVRLIRDYDPSLPELPHDPEQIEQ
VLLNIVRNALQALGPEGGEITLRTRTAFQLTLHGERYRLAARIDVEDNGPGIPPHLQDTLFYPMVSGREGGTGLGLSIAR
NLIDQHAGKIEFTSWPGHTEFSVYLPIRK

Sequences:

>Translated_349_residues
MASGIQPDAGQILNSLINSVLVVDDALAIHYANPAAQQLLAQSSRKLFGTPLPELLSYFSLNIDLMRESLAAGQGFTDNE
VTLVIDSRSHILSLTAQRLPDDFILLEMAPMDNQRRLSQEQLQHAQQIAARDLVRGLAHEIKNPLGGLRGAAQLLSKALP
DPALTEYTKVIIEQADRLRNLVDRLLGPQHPGMHITESIHKVAERVVALVSMELPDNVRLIRDYDPSLPELPHDPEQIEQ
VLLNIVRNALQALGPEGGEITLRTRTAFQLTLHGERYRLAARIDVEDNGPGIPPHLQDTLFYPMVSGREGGTGLGLSIAR
NLIDQHAGKIEFTSWPGHTEFSVYLPIRK
>Mature_348_residues
ASGIQPDAGQILNSLINSVLVVDDALAIHYANPAAQQLLAQSSRKLFGTPLPELLSYFSLNIDLMRESLAAGQGFTDNEV
TLVIDSRSHILSLTAQRLPDDFILLEMAPMDNQRRLSQEQLQHAQQIAARDLVRGLAHEIKNPLGGLRGAAQLLSKALPD
PALTEYTKVIIEQADRLRNLVDRLLGPQHPGMHITESIHKVAERVVALVSMELPDNVRLIRDYDPSLPELPHDPEQIEQV
LLNIVRNALQALGPEGGEITLRTRTAFQLTLHGERYRLAARIDVEDNGPGIPPHLQDTLFYPMVSGREGGTGLGLSIARN
LIDQHAGKIEFTSWPGHTEFSVYLPIRK

Specific function: NtrB acts as a signal transducer which responds to the nitrogen level of cell and modulates the activity of ntrC. In nitrogen limitation ntrB activates ntrC by phosphorylating it, while in nitrogen excess ntrC is dephosphorylated and consequently inactiva

COG id: COG3852

COG function: function code T; Signal transduction histidine kinase, nitrogen specific

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1790300, Length=349, Percent_Identity=92.5501432664756, Blast_Score=657, Evalue=0.0,
Organism=Escherichia coli, GI1788549, Length=354, Percent_Identity=28.2485875706215, Blast_Score=125, Evalue=5e-30,
Organism=Escherichia coli, GI1790436, Length=240, Percent_Identity=29.5833333333333, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI87081816, Length=229, Percent_Identity=31.0043668122271, Blast_Score=81, Evalue=1e-16,
Organism=Escherichia coli, GI1786600, Length=351, Percent_Identity=26.2108262108262, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI87082128, Length=233, Percent_Identity=30.4721030042918, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789149, Length=236, Percent_Identity=27.5423728813559, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1786912, Length=270, Percent_Identity=28.8888888888889, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1789808, Length=221, Percent_Identity=28.9592760180996, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI48994928, Length=242, Percent_Identity=28.9256198347107, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1790567, Length=345, Percent_Identity=26.3768115942029, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1790346, Length=250, Percent_Identity=26, Blast_Score=62, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR000014
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 38543; Mature: 38412

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASGIQPDAGQILNSLINSVLVVDDALAIHYANPAAQQLLAQSSRKLFGTPLPELLSYFS
CCCCCCCCHHHHHHHHHHHHHHHHCHHEEEECCHHHHHHHHHHHHHHCCCCHHHHHHHHH
LNIDLMRESLAAGQGFTDNEVTLVIDSRSHILSLTAQRLPDDFILLEMAPMDNQRRLSQE
HHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHH
QLQHAQQIAARDLVRGLAHEIKNPLGGLRGAAQLLSKALPDPALTEYTKVIIEQADRLRN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LVDRLLGPQHPGMHITESIHKVAERVVALVSMELPDNVRLIRDYDPSLPELPHDPEQIEQ
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCHHHHHH
VLLNIVRNALQALGPEGGEITLRTRTAFQLTLHGERYRLAARIDVEDNGPGIPPHLQDTL
HHHHHHHHHHHHHCCCCCEEEEEEEEEEEEEECCCEEEEEEEEEECCCCCCCCCCCHHHH
FYPMVSGREGGTGLGLSIARNLIDQHAGKIEFTSWPGHTEFSVYLPIRK
HHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCEEEEEEECCC
>Mature Secondary Structure 
ASGIQPDAGQILNSLINSVLVVDDALAIHYANPAAQQLLAQSSRKLFGTPLPELLSYFS
CCCCCCCHHHHHHHHHHHHHHHHCHHEEEECCHHHHHHHHHHHHHHCCCCHHHHHHHHH
LNIDLMRESLAAGQGFTDNEVTLVIDSRSHILSLTAQRLPDDFILLEMAPMDNQRRLSQE
HHHHHHHHHHHHCCCCCCCCEEEEECCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHH
QLQHAQQIAARDLVRGLAHEIKNPLGGLRGAAQLLSKALPDPALTEYTKVIIEQADRLRN
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LVDRLLGPQHPGMHITESIHKVAERVVALVSMELPDNVRLIRDYDPSLPELPHDPEQIEQ
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCCCCCCCCCHHHHHH
VLLNIVRNALQALGPEGGEITLRTRTAFQLTLHGERYRLAARIDVEDNGPGIPPHLQDTL
HHHHHHHHHHHHHCCCCCEEEEEEEEEEEEEECCCEEEEEEEEEECCCCCCCCCCCHHHH
FYPMVSGREGGTGLGLSIARNLIDQHAGKIEFTSWPGHTEFSVYLPIRK
HHHCCCCCCCCCCCHHHHHHHHHHHCCCCEEEECCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]