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The map label for this gene is yifK [H]

Identifier: 29143689

GI number: 29143689

Start: 3465825

End: 3467210

Strand: Reverse

Name: yifK [H]

Synonym: t3367

Alternate gene names: 29143689

Gene position: 3467210-3465825 (Counterclockwise)

Preceding gene: 29143690

Following gene: 29143684

Centisome position: 72.35

GC content: 54.4

Gene sequence:

>1386_bases
ATGGCAGAGAAAAAACCGGAGCTACAGCGTGGGCTGGAAGCTCGTCATATTGAATTGATTGCCCTCGGGGGCACCATCGG
CGTCGGACTCTTTATGGGCGCCGCCAGTACGCTGAAATGGGCGGGCCCGTCAGTGCTGCTGGCGTATATCATCGCCGGAT
TGTTCGTCTTTTTCATCATGCGTTCGATGGGGGAGATGCTCTTTCTGGAACCTGTTACCGGCTCCTTTGCCGTGTACGCC
CACCGGTATATGAGTCCTTTTTTTGGCTATCTTACCGCCTGGTCATACTGGTTTATGTGGATGGCGGTCGGGATCTCGGA
AATTACCGCCATTGGGGTCTACGTCCAGTTCTGGTTTCCGGAGATGGCGCAGTGGATACCGGCGCTGATTGCCGTCGGAC
TGGTCGCGTTGGCGAATCTGGCTGCGGTGCGCCTGTATGGTGAAATCGAGTTCTGGTTTGCGATGATCAAAGTCACCACG
ATTATTGTGATGATCATCATCGGCCTGGGGGTGATTTTCTTCGGCTTTGGTAACGGCGGCCAGGCGATTGGCTTTGGTAA
TCTGACCGAGCATGGCGGCTTTTTTGCCGGCGGCTGGAAAGGCTTTCTGACCGCATTATGTATCGTGGTGGCCTCTTATC
AAGGGGTTGAGTTGATCGGTATTACCGCCGGTGAAGCGAAGAATCCGCAGGTGACGTTGCGTAGCGCGGTGGGTAAAGTG
CTGTGGCGTATCCTGATTTTTTATGTTGGCGCGATTTTCGTGATCGTCACCATTTTCCCGTGGAATGAGATTGGCAGCAA
CGGCAGCCCCTTTGTGCTCACCTTCGCGAAAATCGGCATCACCGCCGCGGCAGGCATTATCAACTTTGTCGTGCTGACGG
CGGCGCTCTCCGGCTGTAACAGCGGAATGTATAGCTGTGGGCGTATGCTTTACGCGCTGGCGAAAAACCGTCAACTGCCG
GCGGCAGTTGCGAAGGTCTCTCGCCACGGCGTGCCGGTCGCGGGCGTGGCGCTCTCTATTTTGATTTTGCTGGTAGGTTC
TTGCCTGAACTACATTATCCCCAATCCGCAGCGCGTCTTTGTTTACGTTTATAGCGCCAGCGTACTGCCGGGGATGGTGC
CGTGGTTTGTCATTCTGATTAGCCAACTGCGCTTTCGTCGGGCGCATAAAGAAGCGATTGCGGATCATCCTTTTCGTTCC
ATTATGTTTCCGTGGGCGAACTATTTGACGATGGCGTTTCTGGTTTGCGTTTTAATCGGCATGTACTTTAATGAAGATAC
GCGCATGTCGCTGTTTGTCGGCGTCATCTTCCTGCTGGCCGTCACGCTGGTCTACAAAGTTTTCGGCCTGAATCGTCACG
GAACCGCCCACAAGGTGGGGGAATAA

Upstream 100 bases:

>100_bases
TTGCCATTTGTCCAAATTTAAGAAAATATTCGCAACAATCGATGTACCCATAACAATAACCGGTACTACCGGAACCGTTG
CAAACACGACATGAGGATTT

Downstream 100 bases:

>100_bases
GCGCCAAAATGCGCAAAGCATAACCAAACGCGCATTTTATTTAAAAAGGCACTGGACAGCGGGGTGTGAAGTCCGTATTA
TCCACCCCCGCAACGGCGCT

Product: transport protein YifK

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 461; Mature: 460

Protein sequence:

>461_residues
MAEKKPELQRGLEARHIELIALGGTIGVGLFMGAASTLKWAGPSVLLAYIIAGLFVFFIMRSMGEMLFLEPVTGSFAVYA
HRYMSPFFGYLTAWSYWFMWMAVGISEITAIGVYVQFWFPEMAQWIPALIAVGLVALANLAAVRLYGEIEFWFAMIKVTT
IIVMIIIGLGVIFFGFGNGGQAIGFGNLTEHGGFFAGGWKGFLTALCIVVASYQGVELIGITAGEAKNPQVTLRSAVGKV
LWRILIFYVGAIFVIVTIFPWNEIGSNGSPFVLTFAKIGITAAAGIINFVVLTAALSGCNSGMYSCGRMLYALAKNRQLP
AAVAKVSRHGVPVAGVALSILILLVGSCLNYIIPNPQRVFVYVYSASVLPGMVPWFVILISQLRFRRAHKEAIADHPFRS
IMFPWANYLTMAFLVCVLIGMYFNEDTRMSLFVGVIFLLAVTLVYKVFGLNRHGTAHKVGE

Sequences:

>Translated_461_residues
MAEKKPELQRGLEARHIELIALGGTIGVGLFMGAASTLKWAGPSVLLAYIIAGLFVFFIMRSMGEMLFLEPVTGSFAVYA
HRYMSPFFGYLTAWSYWFMWMAVGISEITAIGVYVQFWFPEMAQWIPALIAVGLVALANLAAVRLYGEIEFWFAMIKVTT
IIVMIIIGLGVIFFGFGNGGQAIGFGNLTEHGGFFAGGWKGFLTALCIVVASYQGVELIGITAGEAKNPQVTLRSAVGKV
LWRILIFYVGAIFVIVTIFPWNEIGSNGSPFVLTFAKIGITAAAGIINFVVLTAALSGCNSGMYSCGRMLYALAKNRQLP
AAVAKVSRHGVPVAGVALSILILLVGSCLNYIIPNPQRVFVYVYSASVLPGMVPWFVILISQLRFRRAHKEAIADHPFRS
IMFPWANYLTMAFLVCVLIGMYFNEDTRMSLFVGVIFLLAVTLVYKVFGLNRHGTAHKVGE
>Mature_460_residues
AEKKPELQRGLEARHIELIALGGTIGVGLFMGAASTLKWAGPSVLLAYIIAGLFVFFIMRSMGEMLFLEPVTGSFAVYAH
RYMSPFFGYLTAWSYWFMWMAVGISEITAIGVYVQFWFPEMAQWIPALIAVGLVALANLAAVRLYGEIEFWFAMIKVTTI
IVMIIIGLGVIFFGFGNGGQAIGFGNLTEHGGFFAGGWKGFLTALCIVVASYQGVELIGITAGEAKNPQVTLRSAVGKVL
WRILIFYVGAIFVIVTIFPWNEIGSNGSPFVLTFAKIGITAAAGIINFVVLTAALSGCNSGMYSCGRMLYALAKNRQLPA
AVAKVSRHGVPVAGVALSILILLVGSCLNYIIPNPQRVFVYVYSASVLPGMVPWFVILISQLRFRRAHKEAIADHPFRSI
MFPWANYLTMAFLVCVLIGMYFNEDTRMSLFVGVIFLLAVTLVYKVFGLNRHGTAHKVGE

Specific function: Probable amino-acid or metabolite transport protein [H]

COG id: COG1113

COG function: function code E; Gamma-aminobutyrate permease and related permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily [H]

Homologues:

Organism=Escherichia coli, GI48994972, Length=461, Percent_Identity=95.2277657266811, Blast_Score=861, Evalue=0.0,
Organism=Escherichia coli, GI1786789, Length=429, Percent_Identity=44.0559440559441, Blast_Score=375, Evalue=1e-105,
Organism=Escherichia coli, GI1786302, Length=457, Percent_Identity=39.1684901531729, Blast_Score=343, Evalue=2e-95,
Organism=Escherichia coli, GI1790653, Length=462, Percent_Identity=38.7445887445887, Blast_Score=340, Evalue=2e-94,
Organism=Escherichia coli, GI1786602, Length=436, Percent_Identity=45.8715596330275, Blast_Score=334, Evalue=7e-93,
Organism=Escherichia coli, GI1788480, Length=435, Percent_Identity=39.7701149425287, Blast_Score=294, Evalue=7e-81,
Organism=Escherichia coli, GI87081915, Length=463, Percent_Identity=37.5809935205184, Blast_Score=294, Evalue=9e-81,
Organism=Escherichia coli, GI87081708, Length=468, Percent_Identity=36.1111111111111, Blast_Score=288, Evalue=6e-79,
Organism=Escherichia coli, GI1789017, Length=464, Percent_Identity=31.8965517241379, Blast_Score=246, Evalue=3e-66,
Organism=Escherichia coli, GI2367353, Length=412, Percent_Identity=25.7281553398058, Blast_Score=75, Evalue=1e-14,
Organism=Saccharomyces cerevisiae, GI6324061, Length=442, Percent_Identity=35.972850678733, Blast_Score=235, Evalue=1e-62,
Organism=Saccharomyces cerevisiae, GI6320772, Length=474, Percent_Identity=31.4345991561181, Blast_Score=220, Evalue=4e-58,
Organism=Saccharomyces cerevisiae, GI6324924, Length=415, Percent_Identity=32.7710843373494, Blast_Score=199, Evalue=1e-51,
Organism=Saccharomyces cerevisiae, GI6324990, Length=447, Percent_Identity=30.4250559284116, Blast_Score=192, Evalue=1e-49,
Organism=Saccharomyces cerevisiae, GI6324059, Length=441, Percent_Identity=33.7868480725624, Blast_Score=191, Evalue=1e-49,
Organism=Saccharomyces cerevisiae, GI6322892, Length=438, Percent_Identity=30.365296803653, Blast_Score=186, Evalue=9e-48,
Organism=Saccharomyces cerevisiae, GI6321629, Length=417, Percent_Identity=27.8177458033573, Blast_Score=170, Evalue=4e-43,
Organism=Saccharomyces cerevisiae, GI6319824, Length=438, Percent_Identity=28.310502283105, Blast_Score=170, Evalue=5e-43,
Organism=Saccharomyces cerevisiae, GI6322967, Length=410, Percent_Identity=29.5121951219512, Blast_Score=167, Evalue=2e-42,
Organism=Saccharomyces cerevisiae, GI6321053, Length=421, Percent_Identity=28.978622327791, Blast_Score=164, Evalue=3e-41,
Organism=Saccharomyces cerevisiae, GI6319608, Length=428, Percent_Identity=29.2056074766355, Blast_Score=162, Evalue=7e-41,
Organism=Saccharomyces cerevisiae, GI6319543, Length=401, Percent_Identity=29.6758104738155, Blast_Score=159, Evalue=7e-40,
Organism=Saccharomyces cerevisiae, GI6324553, Length=429, Percent_Identity=29.1375291375291, Blast_Score=154, Evalue=3e-38,
Organism=Saccharomyces cerevisiae, GI6324981, Length=397, Percent_Identity=30.7304785894207, Blast_Score=153, Evalue=4e-38,
Organism=Saccharomyces cerevisiae, GI6320717, Length=439, Percent_Identity=24.6013667425968, Blast_Score=150, Evalue=4e-37,
Organism=Saccharomyces cerevisiae, GI6319542, Length=402, Percent_Identity=26.865671641791, Blast_Score=149, Evalue=1e-36,
Organism=Saccharomyces cerevisiae, GI6320251, Length=439, Percent_Identity=25.5125284738041, Blast_Score=144, Evalue=3e-35,
Organism=Saccharomyces cerevisiae, GI6320364, Length=550, Percent_Identity=24.3636363636364, Blast_Score=107, Evalue=4e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293
- InterPro:   IPR004840 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 50379; Mature: 50248

Theoretical pI: Translated: 9.66; Mature: 9.66

Prosite motif: PS00639 THIOL_PROTEASE_HIS ; PS00218 AMINO_ACID_PERMEASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEKKPELQRGLEARHIELIALGGTIGVGLFMGAASTLKWAGPSVLLAYIIAGLFVFFIM
CCCCCCHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
RSMGEMLFLEPVTGSFAVYAHRYMSPFFGYLTAWSYWFMWMAVGISEITAIGVYVQFWFP
HHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EMAQWIPALIAVGLVALANLAAVRLYGEIEFWFAMIKVTTIIVMIIIGLGVIFFGFGNGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCC
QAIGFGNLTEHGGFFAGGWKGFLTALCIVVASYQGVELIGITAGEAKNPQVTLRSAVGKV
CEEECCCCCCCCCEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHH
LWRILIFYVGAIFVIVTIFPWNEIGSNGSPFVLTFAKIGITAAAGIINFVVLTAALSGCN
HHHHHHHHHHHHHHHHHHCCCHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCC
SGMYSCGRMLYALAKNRQLPAAVAKVSRHGVPVAGVALSILILLVGSCLNYIIPNPQRVF
CCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEE
VYVYSASVLPGMVPWFVILISQLRFRRAHKEAIADHPFRSIMFPWANYLTMAFLVCVLIG
EEEEECHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
MYFNEDTRMSLFVGVIFLLAVTLVYKVFGLNRHGTAHKVGE
HHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
AEKKPELQRGLEARHIELIALGGTIGVGLFMGAASTLKWAGPSVLLAYIIAGLFVFFIM
CCCCCHHHCCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHH
RSMGEMLFLEPVTGSFAVYAHRYMSPFFGYLTAWSYWFMWMAVGISEITAIGVYVQFWFP
HHHCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EMAQWIPALIAVGLVALANLAAVRLYGEIEFWFAMIKVTTIIVMIIIGLGVIFFGFGNGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCC
QAIGFGNLTEHGGFFAGGWKGFLTALCIVVASYQGVELIGITAGEAKNPQVTLRSAVGKV
CEEECCCCCCCCCEECCCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCHHHHHHHHHH
LWRILIFYVGAIFVIVTIFPWNEIGSNGSPFVLTFAKIGITAAAGIINFVVLTAALSGCN
HHHHHHHHHHHHHHHHHHCCCHHCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHCC
SGMYSCGRMLYALAKNRQLPAAVAKVSRHGVPVAGVALSILILLVGSCLNYIIPNPQRVF
CCHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCCEEE
VYVYSASVLPGMVPWFVILISQLRFRRAHKEAIADHPFRSIMFPWANYLTMAFLVCVLIG
EEEEECHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHH
MYFNEDTRMSLFVGVIFLLAVTLVYKVFGLNRHGTAHKVGE
HHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1379743; 9278503 [H]