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The map label for this gene is yhdA [H]

Identifier: 29143623

GI number: 29143623

Start: 3383963

End: 3385903

Strand: Reverse

Name: yhdA [H]

Synonym: t3290

Alternate gene names: 29143623

Gene position: 3385903-3383963 (Counterclockwise)

Preceding gene: 29143637

Following gene: 29143622

Centisome position: 70.66

GC content: 53.53

Gene sequence:

>1941_bases
ATGCGATTAACGACGAAATTCTCAGCTTTTATCACGCTGCTCACGGGATTAACGATCTTCGTGACTCTGATAGGTTGCTC
GCTAAGCTTTTATAACGCCGTACAGTATAAGTATGTCAGCCGTGTGCAGGCGACGGCAACAGCCATTGATACGCACCTGG
TGACCCATGATATTGTCTCGCTGACGCCGCAAATCGACGAGCTCATGATCGCTTCCGATATTGTGCGTGTCGATCTGTTG
CAGGGGGAGCGCAGCGTCTACAGCCATTCTCGCGCCAGAGGTTATCGGCCAGCCGGCACCAGCGACATGTATCGCGAGCT
GGTCGTACCGCTGATAAAACATCCAGGAATGTCGCTACGTCTGGTTTATCAGGACCCGATGGGTAATTATTTTCACTCAC
TGATCACCACGGCGCCGCTGACGCTGGCGATCGGTTTTATCGTTCTGATTTTGTTTTTATCGGTGCGCTGGCTGCAGCGG
CAGCTTTCCGGGCAGGAGCTTCTGGAAATTCGCTCAACGCGTATTCTGAACGGCGAACGCGGGGCGAATGTCCGCGGTTC
TGTTTACGAATGGCCAGCGCGCACCAGTAGCGCGCTTGATGTATTGCTTTCCGAAATTCAGTTTGCTCACGAACAGCGTA
GTCGCCTGGACACCCTCATTCGCTCCTACGCCGCGCAGGACACCAAAACCGGACTCGGTAACCGTCTGTTCTTTGATAAC
CAGCTGGCGACGCTGCTGGAAGATCAGGAAAAAGTGGGAGTGCATGGCGTGGTGATGATGATCCGCTTGCCAGACTTCAA
TCTTCTGCGCGACAGCCTGGGAGGCAATCAGGCGGAAGAGCAGATGTTTATGCTTATCAATCTGCTATCGACATTCATTA
TGCGTTACCCAGGCTCGCTGCTGGCGCGTTATCACCGCAGCGACTTTGCCGTGCTGCTACCGCATCGAACGCTGAAAGAA
GCGGAAAGTATTGCCGGACAACTTTTAAAAGCTGTCGATGCGCTACCGGCTAACAAAATGCTCGATCGTGACGATATGGT
ACATATCGGCATTTGCGCCTGGCGCAGCGGACAGTCCACCGATCAGGTGATGGAACATGCTGAAGCCGCGGCGCGGAATG
CCGCCCTGCAGGGGGGAAATAGCTGGGCTATCTACGACGACACTCTGCCGGAAAAAGGGCGCGGCAATGTGCGCTGGCGC
ACATTGATTGAGCAGATGCTGAACCGGGGCGGACCGCGACTTTATCAAAAACCGGCGGTCACGCGAGAAGGTCGCGTACA
TCATCGGGAATTGATGTGTCGCATCTATGACGGTAAAGAAGAGGTGAGCTCGGCGGAGTATATGCCGATGGTGTTGCAAT
TTGGTTTATCGGAAGAGTATGACAGATTACAAATTAGCCGCCTGATTACGTTGCTGGGCTACTGGCCGGATGAAAATCTG
GCAATGCAGTTGACGGTTGAGTCGCTGATTCGTCCGCGTTTTCAGCGCTGGTTGCGCGATACGTTAATGCAGTGTGAAAA
ATCACAGCGAAATCGCATAATTATTGAACTTGCGGAGGCAGATGTTTGTCAACACATCAGCCGGTTACAACCCATCCTTC
GCTTAGTCAATGCGCTTGGCGTTCGGGTGGCGGTGACACAGGCGGGTTTGACGCTGGTTAGCACGAGCTGGATTAAAGCG
CTCAATGTGGAATTACTCAAGCTGCATCCGAGTCTGGTCAGAAACATTGAGAAGCGAACGGAAAACCAGCTTCTGGTTCA
AAGTCTGGTAGAGGCCTGCGCGGGCACGCCTACGCAGGTTTACGCGACGGGCGTCCGTTCGCGCGGCGAGTGGCAGACGC
TGACAAAACGCGGCGTGGCTGGCGGGCAGGGTGATTTTTTTGCCTCCTCCCAACTACTTGACACAAACGTGAAAAAATAT
TCGCAAAGATACTCGGTTTAA

Upstream 100 bases:

>100_bases
TCCATTTTGGTAGTATGCCTGCTTCATTGCGCGCCGTGGCGAATTCCGCCTTCAGATTCGCTTTTTCATACTGTTTATAA
CCGTCGGAGTTAACTCAAGG

Downstream 100 bases:

>100_bases
CCTGCCGTTTAATTTGTTTTCACGTAGAATAACGCGCGCTGCGCCTCATGGGGGTGTGCTTGTCTGCTCGCCAGATTGTT
GCAGCAAATATGCAGGTGAA

Product: regulatory protein CsrD

Products: NA

Alternate protein names: Regulator of CsrB and CsrC decay CsrD [H]

Number of amino acids: Translated: 646; Mature: 646

Protein sequence:

>646_residues
MRLTTKFSAFITLLTGLTIFVTLIGCSLSFYNAVQYKYVSRVQATATAIDTHLVTHDIVSLTPQIDELMIASDIVRVDLL
QGERSVYSHSRARGYRPAGTSDMYRELVVPLIKHPGMSLRLVYQDPMGNYFHSLITTAPLTLAIGFIVLILFLSVRWLQR
QLSGQELLEIRSTRILNGERGANVRGSVYEWPARTSSALDVLLSEIQFAHEQRSRLDTLIRSYAAQDTKTGLGNRLFFDN
QLATLLEDQEKVGVHGVVMMIRLPDFNLLRDSLGGNQAEEQMFMLINLLSTFIMRYPGSLLARYHRSDFAVLLPHRTLKE
AESIAGQLLKAVDALPANKMLDRDDMVHIGICAWRSGQSTDQVMEHAEAAARNAALQGGNSWAIYDDTLPEKGRGNVRWR
TLIEQMLNRGGPRLYQKPAVTREGRVHHRELMCRIYDGKEEVSSAEYMPMVLQFGLSEEYDRLQISRLITLLGYWPDENL
AMQLTVESLIRPRFQRWLRDTLMQCEKSQRNRIIIELAEADVCQHISRLQPILRLVNALGVRVAVTQAGLTLVSTSWIKA
LNVELLKLHPSLVRNIEKRTENQLLVQSLVEACAGTPTQVYATGVRSRGEWQTLTKRGVAGGQGDFFASSQLLDTNVKKY
SQRYSV

Sequences:

>Translated_646_residues
MRLTTKFSAFITLLTGLTIFVTLIGCSLSFYNAVQYKYVSRVQATATAIDTHLVTHDIVSLTPQIDELMIASDIVRVDLL
QGERSVYSHSRARGYRPAGTSDMYRELVVPLIKHPGMSLRLVYQDPMGNYFHSLITTAPLTLAIGFIVLILFLSVRWLQR
QLSGQELLEIRSTRILNGERGANVRGSVYEWPARTSSALDVLLSEIQFAHEQRSRLDTLIRSYAAQDTKTGLGNRLFFDN
QLATLLEDQEKVGVHGVVMMIRLPDFNLLRDSLGGNQAEEQMFMLINLLSTFIMRYPGSLLARYHRSDFAVLLPHRTLKE
AESIAGQLLKAVDALPANKMLDRDDMVHIGICAWRSGQSTDQVMEHAEAAARNAALQGGNSWAIYDDTLPEKGRGNVRWR
TLIEQMLNRGGPRLYQKPAVTREGRVHHRELMCRIYDGKEEVSSAEYMPMVLQFGLSEEYDRLQISRLITLLGYWPDENL
AMQLTVESLIRPRFQRWLRDTLMQCEKSQRNRIIIELAEADVCQHISRLQPILRLVNALGVRVAVTQAGLTLVSTSWIKA
LNVELLKLHPSLVRNIEKRTENQLLVQSLVEACAGTPTQVYATGVRSRGEWQTLTKRGVAGGQGDFFASSQLLDTNVKKY
SQRYSV
>Mature_646_residues
MRLTTKFSAFITLLTGLTIFVTLIGCSLSFYNAVQYKYVSRVQATATAIDTHLVTHDIVSLTPQIDELMIASDIVRVDLL
QGERSVYSHSRARGYRPAGTSDMYRELVVPLIKHPGMSLRLVYQDPMGNYFHSLITTAPLTLAIGFIVLILFLSVRWLQR
QLSGQELLEIRSTRILNGERGANVRGSVYEWPARTSSALDVLLSEIQFAHEQRSRLDTLIRSYAAQDTKTGLGNRLFFDN
QLATLLEDQEKVGVHGVVMMIRLPDFNLLRDSLGGNQAEEQMFMLINLLSTFIMRYPGSLLARYHRSDFAVLLPHRTLKE
AESIAGQLLKAVDALPANKMLDRDDMVHIGICAWRSGQSTDQVMEHAEAAARNAALQGGNSWAIYDDTLPEKGRGNVRWR
TLIEQMLNRGGPRLYQKPAVTREGRVHHRELMCRIYDGKEEVSSAEYMPMVLQFGLSEEYDRLQISRLITLLGYWPDENL
AMQLTVESLIRPRFQRWLRDTLMQCEKSQRNRIIIELAEADVCQHISRLQPILRLVNALGVRVAVTQAGLTLVSTSWIKA
LNVELLKLHPSLVRNIEKRTENQLLVQSLVEACAGTPTQVYATGVRSRGEWQTLTKRGVAGGQGDFFASSQLLDTNVKKY
SQRYSV

Specific function: Serves as a specificity factor required for RNase E- mediated decay of the small global regulatory RNAs CsrB and CsrC, it is probably not a nuclease. Nor does its activity involve c-di- GMP, despite its domain composition. Positively modulates motility ge

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 GGDEF domain [H]

Homologues:

Organism=Escherichia coli, GI1789650, Length=646, Percent_Identity=84.3653250773994, Blast_Score=1145, Evalue=0.0,
Organism=Escherichia coli, GI1787410, Length=121, Percent_Identity=26.4462809917355, Blast_Score=66, Evalue=8e-12,
Organism=Escherichia coli, GI87081921, Length=414, Percent_Identity=21.0144927536232, Blast_Score=65, Evalue=2e-11,
Organism=Escherichia coli, GI1788849, Length=240, Percent_Identity=24.1666666666667, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF [H]

EC number: NA

Molecular weight: Translated: 73023; Mature: 73023

Theoretical pI: Translated: 9.13; Mature: 9.13

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLTTKFSAFITLLTGLTIFVTLIGCSLSFYNAVQYKYVSRVQATATAIDTHLVTHDIVS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTPQIDELMIASDIVRVDLLQGERSVYSHSRARGYRPAGTSDMYRELVVPLIKHPGMSLR
CCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEE
LVYQDPMGNYFHSLITTAPLTLAIGFIVLILFLSVRWLQRQLSGQELLEIRSTRILNGER
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHEECCCC
GANVRGSVYEWPARTSSALDVLLSEIQFAHEQRSRLDTLIRSYAAQDTKTGLGNRLFFDN
CCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCEEECH
QLATLLEDQEKVGVHGVVMMIRLPDFNLLRDSLGGNQAEEQMFMLINLLSTFIMRYPGSL
HHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHH
LARYHRSDFAVLLPHRTLKEAESIAGQLLKAVDALPANKMLDRDDMVHIGICAWRSGQST
HHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCCCH
DQVMEHAEAAARNAALQGGNSWAIYDDTLPEKGRGNVRWRTLIEQMLNRGGPRLYQKPAV
HHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCEECCCCC
TREGRVHHRELMCRIYDGKEEVSSAEYMPMVLQFGLSEEYDRLQISRLITLLGYWPDENL
CCCCCHHHHHHHHHHCCCHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCC
AMQLTVESLIRPRFQRWLRDTLMQCEKSQRNRIIIELAEADVCQHISRLQPILRLVNALG
EEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHC
VRVAVTQAGLTLVSTSWIKALNVELLKLHPSLVRNIEKRTENQLLVQSLVEACAGTPTQV
CEEEEHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
YATGVRSRGEWQTLTKRGVAGGQGDFFASSQLLDTNVKKYSQRYSV
HHHCCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRLTTKFSAFITLLTGLTIFVTLIGCSLSFYNAVQYKYVSRVQATATAIDTHLVTHDIVS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTPQIDELMIASDIVRVDLLQGERSVYSHSRARGYRPAGTSDMYRELVVPLIKHPGMSLR
CCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEEE
LVYQDPMGNYFHSLITTAPLTLAIGFIVLILFLSVRWLQRQLSGQELLEIRSTRILNGER
EEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHEECCCC
GANVRGSVYEWPARTSSALDVLLSEIQFAHEQRSRLDTLIRSYAAQDTKTGLGNRLFFDN
CCCCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCCEEECH
QLATLLEDQEKVGVHGVVMMIRLPDFNLLRDSLGGNQAEEQMFMLINLLSTFIMRYPGSL
HHHHHHHHHHHCCCCEEEEEEECCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCHHH
LARYHRSDFAVLLPHRTLKEAESIAGQLLKAVDALPANKMLDRDDMVHIGICAWRSGQST
HHHHHCCCCEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEEEEEECCCCCH
DQVMEHAEAAARNAALQGGNSWAIYDDTLPEKGRGNVRWRTLIEQMLNRGGPRLYQKPAV
HHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCCEECCCCC
TREGRVHHRELMCRIYDGKEEVSSAEYMPMVLQFGLSEEYDRLQISRLITLLGYWPDENL
CCCCCHHHHHHHHHHCCCHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCC
AMQLTVESLIRPRFQRWLRDTLMQCEKSQRNRIIIELAEADVCQHISRLQPILRLVNALG
EEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHC
VRVAVTQAGLTLVSTSWIKALNVELLKLHPSLVRNIEKRTENQLLVQSLVEACAGTPTQV
CEEEEHHCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
YATGVRSRGEWQTLTKRGVAGGQGDFFASSQLLDTNVKKYSQRYSV
HHHCCCCCCCHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503; 3049542 [H]