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The map label for this gene is arcB [H]

Identifier: 29143579

GI number: 29143579

Start: 3330509

End: 3332845

Strand: Reverse

Name: arcB [H]

Synonym: t3245

Alternate gene names: 29143579

Gene position: 3332845-3330509 (Counterclockwise)

Preceding gene: 29143580

Following gene: 29143578

Centisome position: 69.55

GC content: 51.73

Gene sequence:

>2337_bases
ATGAAGCAAATTCGTATGCTGGCGCAATACTATGTCGACCTGATGATGAAATTGGGTCTGGTGCGCTTTTCCATGCTCCT
GGCGTTGGCATTGGTGGTGCTGGCGATTGTCGTGCAGATGGCGGTGACCATGGTGCTGCATGGTCAGGTTGAAAGTATCG
ACGTTATTCGTTCCATCTTTTTTGGCCTGTTAATTACGCCCTGGGCGGTCTATTTCTTATCCGTTGTTGTTGAACAACTG
GAAGAGTCAAGGCAGCGACTGTCGCGTCTGGTGCAAAAGCTGGAGGAGATGCGCGAGCGCGATCTCAAGCTTAACGTACA
GTTGAAGGACAATATTGCCCAGCTTAATCAGGAAATTGCCGATCGCGAAAAAGCGGAAGCGGAGCTGCAAGAGACATTTG
AACAGCTAAAAGTAGAAATTAAAGAGCGTGAAGAGGCGCAAATCCAGCTAGAACAGCAATCCTCTTTTCTGCGCTCCTTT
CTGGACGCCTCGCCGGATTTGGTTTTTTATCGTAATGAGGATAAAGAGTTTTCCGGCTGTAACCGCGCAATGGAATTGCT
AACCGGCAAGAGCGAAAAACAGCTGGTGCATTTGAAGCCGGAAGATGTGTACTCTCCCGAAGCGGCGGAGAAAGTCATTG
AAACCGATGAAAAAGTATTCCGCCATAACGTCTCCCTGACCTACGAACAGTGGCTGGATTATCCGGACGGACGAAAGGCC
TGCTTTGAAATTCGTAAAGTGCCTTATTACGACCGTGTCGGTAAACGTCATGGCCTGATGGGATTTGGTCGTGATATTAC
CGAACGTAAGCGTTATCAGGACGCGCTGGAGCGCGCCAGTCGCGACAAGACCACATTTATCTCTACCATCAGTCATGAGC
TGCGCACCCCGCTTAACGGTATCGTCGGTTTAAGCCGCATCCTGCTGGATACCGATCTTACCGCCGAACAGGAAAAATAC
CTTAAGACAATCCATGTCTCCGCCGTGACGTTAGGCAATATTTTCAATGATATCATTGATATGGATAAGATGGAGCGGCG
TAAGGTTCAGCTTGATAACCAACCGGTTGATTTCACCAGCTTTATGGCCGATCTGGAAAACCTTTCCGGTTTGCAGGCGC
AGCAAAAAGGGCTACGTTTTGTGCTTGAGCCGACGCTGCCGCTGCCGCACAAAGTCATTACCGACGGAACGCGTCTGCGC
CAGATTTTATGGAATTTGATCAGCAATGCGGTGAAGTTTACTCAGCAGGGCCAGGTGACGGTGCGGGCGCGCTATGATGA
AGGCGACATGCTGCACTTTGAAGTGGAAGATTCCGGGATCGGCATTCCGCAGGATGAGCAGGATAAAATTTTCGCCATGT
ATTATCAGGTAAAAGACAGTCATGGCGGTAAGCCGGCGACGGGGACCGGTATCGGGCTGGCGGTCTCCCGTCGGCTGGCG
AAAAATATGGGCGGCGATATTACCGTTTCCAGTCTGCCGGGCAAAGGATCGACCTTTACGCTAACGGTTCATGCGCCAGC
GGTGGCGGAAGAGGTGGAGGACGCCTTTGATGAAGACGACATGCCGCTGCCCGCGCTGCATGTTCTGCTGGTCGAAGATA
TTGAACTGAACGTGATTGTGGCGCGTTCAGTACTGGAAAAACTGGGGAACAGCGTGGATGTCGCGATGACCGGCAAGGCG
GCGCTGGAGATGTTCGCGCCAGGCGAATATGACCTGGTCTTACTGGATATTCAGCTACCGGATATGACGGGTCTGGATAT
TGCCAGAGAACTGACCCGTCGCCACACGCGGGAAGATTTACCGCCGCTGGTAGCGCTTACGGCTAACGTTCTGAAAGATA
AAAAAGAGTATCTGGACGCTGGTATGGACGATGTGCTGAGTAAGCCGCTGTCGGTGCCAGCCTTAACCGCGATGATTAAA
AAATTCTGGGATGCCACCGATAAAGAGGAGAGTACCGTGACGCCTGAAGAGAGCGATAAAGCGCAAGCGCTGCTGGATAT
CCCGATGCTGGAACAATACATCGAGTTGGTTGGGCCTAAATTGATCACCGACGGCCTCGCGGTGTTTGAAAAAATGATGC
TTGGCTATTTAAGCGTGCTGGAGTCCAATCTGACGGCGCGTGACAAAAAAGGCGTCGTTGAGGAAGGGCATAAGATTAAA
GGCGCCGCCGGTTCGGTAGGGCTGCGTCATCTGCAACAACTTGGCCAGCAAATCCAGTCGCCGGATCTTCCCGCCTGGGA
AGATAATGTCGTGGAATGGATTGAAGAGATGAAGCAGGAGTGGCAGCACGATGTCGCGGTGCTGAAAGCCTGGGTGGCAA
ACGCGGAAAAAAAATGA

Upstream 100 bases:

>100_bases
TAGCGTAGCGTGATGAGGGGGCTACGCATATTTCGCACAATATTCAACGCGGTTCCCATAATTGGGTATTATGTGCGAAG
TTGTGGTGAAGGAATCCTCT

Downstream 100 bases:

>100_bases
CCCCGGTTTGACCGGGGTGCGCGAATACTGCGCCAACACCAGGGAAATCGTGGCTGCGCCGTGCTTATTATGATGATGTC
AAAGGCGCAGTCCTGTTTTC

Product: aerobic respiration control sensor protein ArcB

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 778; Mature: 778

Protein sequence:

>778_residues
MKQIRMLAQYYVDLMMKLGLVRFSMLLALALVVLAIVVQMAVTMVLHGQVESIDVIRSIFFGLLITPWAVYFLSVVVEQL
EESRQRLSRLVQKLEEMRERDLKLNVQLKDNIAQLNQEIADREKAEAELQETFEQLKVEIKEREEAQIQLEQQSSFLRSF
LDASPDLVFYRNEDKEFSGCNRAMELLTGKSEKQLVHLKPEDVYSPEAAEKVIETDEKVFRHNVSLTYEQWLDYPDGRKA
CFEIRKVPYYDRVGKRHGLMGFGRDITERKRYQDALERASRDKTTFISTISHELRTPLNGIVGLSRILLDTDLTAEQEKY
LKTIHVSAVTLGNIFNDIIDMDKMERRKVQLDNQPVDFTSFMADLENLSGLQAQQKGLRFVLEPTLPLPHKVITDGTRLR
QILWNLISNAVKFTQQGQVTVRARYDEGDMLHFEVEDSGIGIPQDEQDKIFAMYYQVKDSHGGKPATGTGIGLAVSRRLA
KNMGGDITVSSLPGKGSTFTLTVHAPAVAEEVEDAFDEDDMPLPALHVLLVEDIELNVIVARSVLEKLGNSVDVAMTGKA
ALEMFAPGEYDLVLLDIQLPDMTGLDIARELTRRHTREDLPPLVALTANVLKDKKEYLDAGMDDVLSKPLSVPALTAMIK
KFWDATDKEESTVTPEESDKAQALLDIPMLEQYIELVGPKLITDGLAVFEKMMLGYLSVLESNLTARDKKGVVEEGHKIK
GAAGSVGLRHLQQLGQQIQSPDLPAWEDNVVEWIEEMKQEWQHDVAVLKAWVANAEKK

Sequences:

>Translated_778_residues
MKQIRMLAQYYVDLMMKLGLVRFSMLLALALVVLAIVVQMAVTMVLHGQVESIDVIRSIFFGLLITPWAVYFLSVVVEQL
EESRQRLSRLVQKLEEMRERDLKLNVQLKDNIAQLNQEIADREKAEAELQETFEQLKVEIKEREEAQIQLEQQSSFLRSF
LDASPDLVFYRNEDKEFSGCNRAMELLTGKSEKQLVHLKPEDVYSPEAAEKVIETDEKVFRHNVSLTYEQWLDYPDGRKA
CFEIRKVPYYDRVGKRHGLMGFGRDITERKRYQDALERASRDKTTFISTISHELRTPLNGIVGLSRILLDTDLTAEQEKY
LKTIHVSAVTLGNIFNDIIDMDKMERRKVQLDNQPVDFTSFMADLENLSGLQAQQKGLRFVLEPTLPLPHKVITDGTRLR
QILWNLISNAVKFTQQGQVTVRARYDEGDMLHFEVEDSGIGIPQDEQDKIFAMYYQVKDSHGGKPATGTGIGLAVSRRLA
KNMGGDITVSSLPGKGSTFTLTVHAPAVAEEVEDAFDEDDMPLPALHVLLVEDIELNVIVARSVLEKLGNSVDVAMTGKA
ALEMFAPGEYDLVLLDIQLPDMTGLDIARELTRRHTREDLPPLVALTANVLKDKKEYLDAGMDDVLSKPLSVPALTAMIK
KFWDATDKEESTVTPEESDKAQALLDIPMLEQYIELVGPKLITDGLAVFEKMMLGYLSVLESNLTARDKKGVVEEGHKIK
GAAGSVGLRHLQQLGQQIQSPDLPAWEDNVVEWIEEMKQEWQHDVAVLKAWVANAEKK
>Mature_778_residues
MKQIRMLAQYYVDLMMKLGLVRFSMLLALALVVLAIVVQMAVTMVLHGQVESIDVIRSIFFGLLITPWAVYFLSVVVEQL
EESRQRLSRLVQKLEEMRERDLKLNVQLKDNIAQLNQEIADREKAEAELQETFEQLKVEIKEREEAQIQLEQQSSFLRSF
LDASPDLVFYRNEDKEFSGCNRAMELLTGKSEKQLVHLKPEDVYSPEAAEKVIETDEKVFRHNVSLTYEQWLDYPDGRKA
CFEIRKVPYYDRVGKRHGLMGFGRDITERKRYQDALERASRDKTTFISTISHELRTPLNGIVGLSRILLDTDLTAEQEKY
LKTIHVSAVTLGNIFNDIIDMDKMERRKVQLDNQPVDFTSFMADLENLSGLQAQQKGLRFVLEPTLPLPHKVITDGTRLR
QILWNLISNAVKFTQQGQVTVRARYDEGDMLHFEVEDSGIGIPQDEQDKIFAMYYQVKDSHGGKPATGTGIGLAVSRRLA
KNMGGDITVSSLPGKGSTFTLTVHAPAVAEEVEDAFDEDDMPLPALHVLLVEDIELNVIVARSVLEKLGNSVDVAMTGKA
ALEMFAPGEYDLVLLDIQLPDMTGLDIARELTRRHTREDLPPLVALTANVLKDKKEYLDAGMDDVLSKPLSVPALTAMIK
KFWDATDKEESTVTPEESDKAQALLDIPMLEQYIELVGPKLITDGLAVFEKMMLGYLSVLESNLTARDKKGVVEEGHKIK
GAAGSVGLRHLQQLGQQIQSPDLPAWEDNVVEWIEEMKQEWQHDVAVLKAWVANAEKK

Specific function: Member of the two-component regulatory system ArcB/ArcA. Sensor-regulator protein for anaerobic repression of the arc modulon. Activates ArcA via a four-step phosphorelay. ArcB can also dephosphorylate ArcA by a reverse phosphorelay involving His- 717 and

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=778, Percent_Identity=93.8303341902314, Blast_Score=1470, Evalue=0.0,
Organism=Escherichia coli, GI1788713, Length=662, Percent_Identity=27.190332326284, Blast_Score=200, Evalue=3e-52,
Organism=Escherichia coli, GI87081816, Length=513, Percent_Identity=27.2904483430799, Blast_Score=186, Evalue=6e-48,
Organism=Escherichia coli, GI1789149, Length=380, Percent_Identity=31.0526315789474, Blast_Score=171, Evalue=1e-43,
Organism=Escherichia coli, GI145693157, Length=248, Percent_Identity=34.2741935483871, Blast_Score=139, Evalue=6e-34,
Organism=Escherichia coli, GI1790436, Length=246, Percent_Identity=30.8943089430894, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI1788549, Length=423, Percent_Identity=25.7683215130024, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1786912, Length=244, Percent_Identity=28.6885245901639, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1786600, Length=359, Percent_Identity=26.7409470752089, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1790861, Length=220, Percent_Identity=24.0909090909091, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI87082128, Length=224, Percent_Identity=26.7857142857143, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1790346, Length=204, Percent_Identity=25.9803921568627, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1788393, Length=226, Percent_Identity=23.4513274336283, Blast_Score=66, Evalue=7e-12,
Organism=Escherichia coli, GI1786783, Length=239, Percent_Identity=24.2677824267782, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1789402, Length=128, Percent_Identity=34.375, Blast_Score=64, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=215, Percent_Identity=26.9767441860465, Blast_Score=70, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR014409
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 87994; Mature: 87994

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: PS50894 HPT ; PS50112 PAS ; PS50113 PAC ; PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQIRMLAQYYVDLMMKLGLVRFSMLLALALVVLAIVVQMAVTMVLHGQVESIDVIRSIF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
FGLLITPWAVYFLSVVVEQLEESRQRLSRLVQKLEEMRERDLKLNVQLKDNIAQLNQEIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHH
DREKAEAELQETFEQLKVEIKEREEAQIQLEQQSSFLRSFLDASPDLVFYRNEDKEFSGC
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHH
NRAMELLTGKSEKQLVHLKPEDVYSPEAAEKVIETDEKVFRHNVSLTYEQWLDYPDGRKA
HHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCEEHHHHCCCCCCHHH
CFEIRKVPYYDRVGKRHGLMGFGRDITERKRYQDALERASRDKTTFISTISHELRTPLNG
HHHHHCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHH
IVGLSRILLDTDLTAEQEKYLKTIHVSAVTLGNIFNDIIDMDKMERRKVQLDNQPVDFTS
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
FMADLENLSGLQAQQKGLRFVLEPTLPLPHKVITDGTRLRQILWNLISNAVKFTQQGQVT
HHHHHHHHCCCHHHHCCCEEEECCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEE
VRARYDEGDMLHFEVEDSGIGIPQDEQDKIFAMYYQVKDSHGGKPATGTGIGLAVSRRLA
EEEEECCCCEEEEEECCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHH
KNMGGDITVSSLPGKGSTFTLTVHAPAVAEEVEDAFDEDDMPLPALHVLLVEDIELNVIV
HHCCCCEEEECCCCCCCEEEEEEECCHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHH
ARSVLEKLGNSVDVAMTGKAALEMFAPGEYDLVLLDIQLPDMTGLDIARELTRRHTREDL
HHHHHHHCCCCEEEEEECHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCC
PPLVALTANVLKDKKEYLDAGMDDVLSKPLSVPALTAMIKKFWDATDKEESTVTPEESDK
CHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCH
AQALLDIPMLEQYIELVGPKLITDGLAVFEKMMLGYLSVLESNLTARDKKGVVEEGHKIK
HHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCC
GAAGSVGLRHLQQLGQQIQSPDLPAWEDNVVEWIEEMKQEWQHDVAVLKAWVANAEKK
CCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MKQIRMLAQYYVDLMMKLGLVRFSMLLALALVVLAIVVQMAVTMVLHGQVESIDVIRSIF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
FGLLITPWAVYFLSVVVEQLEESRQRLSRLVQKLEEMRERDLKLNVQLKDNIAQLNQEIA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEHHHHHHHHHHHH
DREKAEAELQETFEQLKVEIKEREEAQIQLEQQSSFLRSFLDASPDLVFYRNEDKEFSGC
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHH
NRAMELLTGKSEKQLVHLKPEDVYSPEAAEKVIETDEKVFRHNVSLTYEQWLDYPDGRKA
HHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHCCCEEHHHHCCCCCCHHH
CFEIRKVPYYDRVGKRHGLMGFGRDITERKRYQDALERASRDKTTFISTISHELRTPLNG
HHHHHCCCCHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHH
IVGLSRILLDTDLTAEQEKYLKTIHVSAVTLGNIFNDIIDMDKMERRKVQLDNQPVDFTS
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
FMADLENLSGLQAQQKGLRFVLEPTLPLPHKVITDGTRLRQILWNLISNAVKFTQQGQVT
HHHHHHHHCCCHHHHCCCEEEECCCCCCCHHHHCCCHHHHHHHHHHHHHHHHHCCCCCEE
VRARYDEGDMLHFEVEDSGIGIPQDEQDKIFAMYYQVKDSHGGKPATGTGIGLAVSRRLA
EEEEECCCCEEEEEECCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCCCHHHHHHHHHH
KNMGGDITVSSLPGKGSTFTLTVHAPAVAEEVEDAFDEDDMPLPALHVLLVEDIELNVIV
HHCCCCEEEECCCCCCCEEEEEEECCHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCHHHH
ARSVLEKLGNSVDVAMTGKAALEMFAPGEYDLVLLDIQLPDMTGLDIARELTRRHTREDL
HHHHHHHCCCCEEEEEECHHHHHHCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHCC
PPLVALTANVLKDKKEYLDAGMDDVLSKPLSVPALTAMIKKFWDATDKEESTVTPEESDK
CHHHHHHHHHHHHHHHHHHCCHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCH
AQALLDIPMLEQYIELVGPKLITDGLAVFEKMMLGYLSVLESNLTARDKKGVVEEGHKIK
HHHHHCCHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHCCCCCC
GAAGSVGLRHLQQLGQQIQSPDLPAWEDNVVEWIEEMKQEWQHDVAVLKAWVANAEKK
CCHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]