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The map label for this gene is yrbG [H]

Identifier: 29143565

GI number: 29143565

Start: 3319992

End: 3320969

Strand: Direct

Name: yrbG [H]

Synonym: t3231

Alternate gene names: 29143565

Gene position: 3319992-3320969 (Clockwise)

Preceding gene: 29143557

Following gene: 29143566

Centisome position: 69.28

GC content: 55.42

Gene sequence:

>978_bases
ATGCTTTTAGCGATGGCGCTACTCATAATTGGTTTGCTTCTGGTGGCCTACGGCGCCGATCGTCTGGTGTTTGCGGCCTC
TATTTTATGCCGTACATTCGGTATTCCCCCGCTGATCATCGGGATGACGGTCGTGAGTATCGGCACCTCGCTGCCGGAAA
TTATTGTGTCGGTCGCCGCATCGCTACACGGTCAGCTCGATTTGGCCGTCGGCGCGGCGCTCGGTTCTAACATCACCAAT
ATTTTGCTGATCTTAGGGCTGGCGGCGCTGGTTCGTCCATTTACCGTGCATTCCGATGTTCTACGTCGCGAATTGCCATT
AATGTTATTTGTTAGCGTGGTAGCCGGTTCCGTACTGCATGACGGACAGTTAAGTCGCAGTGATGGTATCTTTCTCCTGC
TTCTGGCTGTGCTATGGCTGTTATTCATTGTTAAAATCGCGCGTCTGGCCGAACGCCAGGGGAATGACAGCCTCACCCGC
GAACAACTGGCGGAGCTGCCGCGCGAAGACGGGCTCCCCGTCGCGTTCTTATGGCTGGGCATTGCGCTGGTCATCATGCC
GATGGCGACGCGCATGGTAATCGATAACGCTACGGTGCTGGCGAACTATTTCGCCATGAGTGAATTAACGCTCGGTCTGA
CAGTCATCGCCGTCGGCACCAGTCTGCCAGAACTGGCGACGGCGATTGCCGGCGTGCGAAAAGGCGAAAATGATATTGCC
GTTGGTAATCTCATTGGCGCCAATATTTTTAATCTCGCCATCGTGCTGGGACTGCCTGCGCTGATCGCGCCGGGGGAGAT
CAACCCGCTGGCGTTTGGGCGTGATTATAGCGTGATGTTGCTGGTTAGCGTGGTTTTCGCTTTACTTTGCTGGCGGCATC
CGCGCCAGATTGGCCGGGGCGCAGGTATACTGCTGACCGGCGGGTTTATCGTATGGCTGGCGATGCTCTATTGGCTATCG
CCACTTCTTGTTGGATAA

Upstream 100 bases:

>100_bases
TTTACTTTTTAGCCGCATAAAGTCAAAATTAGGACTTCGTTACGGCTTCCAGATATCCCTTCCAGGGGACCGGCGAGTAT
ACCTGAAGAAAGGACTTTAG

Downstream 100 bases:

>100_bases
CTGGAAACGGATTATGTCGCATTTAGCGTTGCAACCGGGGTTTGACTTTCAGCAGGCAGGCAAAGAGGTCCTGGAAATTG
AACGTGAAGGCCTGGCGGAG

Product: calcium/sodium:proton antiporter

Products: Na (I) [Cytoplasm]; Ca (II) [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MLLAMALLIIGLLLVAYGADRLVFAASILCRTFGIPPLIIGMTVVSIGTSLPEIIVSVAASLHGQLDLAVGAALGSNITN
ILLILGLAALVRPFTVHSDVLRRELPLMLFVSVVAGSVLHDGQLSRSDGIFLLLLAVLWLLFIVKIARLAERQGNDSLTR
EQLAELPREDGLPVAFLWLGIALVIMPMATRMVIDNATVLANYFAMSELTLGLTVIAVGTSLPELATAIAGVRKGENDIA
VGNLIGANIFNLAIVLGLPALIAPGEINPLAFGRDYSVMLLVSVVFALLCWRHPRQIGRGAGILLTGGFIVWLAMLYWLS
PLLVG

Sequences:

>Translated_325_residues
MLLAMALLIIGLLLVAYGADRLVFAASILCRTFGIPPLIIGMTVVSIGTSLPEIIVSVAASLHGQLDLAVGAALGSNITN
ILLILGLAALVRPFTVHSDVLRRELPLMLFVSVVAGSVLHDGQLSRSDGIFLLLLAVLWLLFIVKIARLAERQGNDSLTR
EQLAELPREDGLPVAFLWLGIALVIMPMATRMVIDNATVLANYFAMSELTLGLTVIAVGTSLPELATAIAGVRKGENDIA
VGNLIGANIFNLAIVLGLPALIAPGEINPLAFGRDYSVMLLVSVVFALLCWRHPRQIGRGAGILLTGGFIVWLAMLYWLS
PLLVG
>Mature_325_residues
MLLAMALLIIGLLLVAYGADRLVFAASILCRTFGIPPLIIGMTVVSIGTSLPEIIVSVAASLHGQLDLAVGAALGSNITN
ILLILGLAALVRPFTVHSDVLRRELPLMLFVSVVAGSVLHDGQLSRSDGIFLLLLAVLWLLFIVKIARLAERQGNDSLTR
EQLAELPREDGLPVAFLWLGIALVIMPMATRMVIDNATVLANYFAMSELTLGLTVIAVGTSLPELATAIAGVRKGENDIA
VGNLIGANIFNLAIVLGLPALIAPGEINPLAFGRDYSVMLLVSVVFALLCWRHPRQIGRGAGILLTGGFIVWLAMLYWLS
PLLVG

Specific function: Unknown

COG id: COG0530

COG function: function code P; Ca2+/Na+ antiporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sodium/potassium/calcium exchanger family [H]

Homologues:

Organism=Escherichia coli, GI1789587, Length=324, Percent_Identity=87.3456790123457, Blast_Score=490, Evalue=1e-140,
Organism=Drosophila melanogaster, GI24643941, Length=156, Percent_Identity=30.1282051282051, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI45550690, Length=156, Percent_Identity=30.1282051282051, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004481
- InterPro:   IPR004837 [H]

Pfam domain/function: PF01699 Na_Ca_ex [H]

EC number: NA

Molecular weight: Translated: 34507; Mature: 34507

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLLAMALLIIGLLLVAYGADRLVFAASILCRTFGIPPLIIGMTVVSIGTSLPEIIVSVAA
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHH
SLHGQLDLAVGAALGSNITNILLILGLAALVRPFTVHSDVLRRELPLMLFVSVVAGSVLH
HHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DGQLSRSDGIFLLLLAVLWLLFIVKIARLAERQGNDSLTREQLAELPREDGLPVAFLWLG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHHHHH
IALVIMPMATRMVIDNATVLANYFAMSELTLGLTVIAVGTSLPELATAIAGVRKGENDIA
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHCCCCCEE
VGNLIGANIFNLAIVLGLPALIAPGEINPLAFGRDYSVMLLVSVVFALLCWRHPRQIGRG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHCCC
AGILLTGGFIVWLAMLYWLSPLLVG
CCEEEECHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLLAMALLIIGLLLVAYGADRLVFAASILCRTFGIPPLIIGMTVVSIGTSLPEIIVSVAA
CHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCHHHHHHHHHHH
SLHGQLDLAVGAALGSNITNILLILGLAALVRPFTVHSDVLRRELPLMLFVSVVAGSVLH
HHCCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
DGQLSRSDGIFLLLLAVLWLLFIVKIARLAERQGNDSLTREQLAELPREDGLPVAFLWLG
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCCCCHHHHHHH
IALVIMPMATRMVIDNATVLANYFAMSELTLGLTVIAVGTSLPELATAIAGVRKGENDIA
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHHHHCCCCCEE
VGNLIGANIFNLAIVLGLPALIAPGEINPLAFGRDYSVMLLVSVVFALLCWRHPRQIGRG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHCHHHHCCC
AGILLTGGFIVWLAMLYWLSPLLVG
CCEEEECHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Na (I) [Periplasm]; Ca (II) [Cytoplasm] [C]

Specific reaction: Na (I) [Periplasm] + Ca (II) [Cytoplasm] = Na (I) [Cytoplasm] + Ca (II) [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]