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The map label for this gene is alx

Identifier: 29143483

GI number: 29143483

Start: 3235268

End: 3236236

Strand: Direct

Name: alx

Synonym: t3144

Alternate gene names: 29143483

Gene position: 3235268-3236236 (Clockwise)

Preceding gene: 29143482

Following gene: 29143484

Centisome position: 67.51

GC content: 52.43

Gene sequence:

>969_bases
ATGAATACTGTTGGTACGCCATTATTATGGGGTGGATTCGCGGTTGTTGTGGTGATAATGCTATCCATCGACTTGTTGTT
GCAGGGACGCCGTGGCGCACATGCGATGTCGATGAAACAAGCGGCAGGATGGTCAATCCTGTGGGTAACGCTCTCGCTAC
TGTTTAACGCCGCTTTCTGGTGGTATCTGGCTGAAACGCAAGGGCGCGAAGTTGCTGACCCGCAGGCATTAGCGTTCCTT
ACCGGCTATCTGATTGAAAAGTCGCTGGCCGTAGATAACGTCTTTGTCTGGCTGATGCTGTTTAGCTATTTCTCCGTCCC
TCCGGCTCTGCAACGCCGGGTGCTGGTGTATGGGGTTCTTGGCGCGATCGTGTTGCGTACTATCATGATTTTCGCCGGTA
CCTGGCTTATCACTCAGTTCGAATGGCTGCTGTATGTGTTCGGCGCCTTCTTGCTGTTTACCGGCGTAAAAATGGCGCTG
GCGAAGGAAGACGAATCCGGCATTGGCGAAAAACCGATGGTGCGTTGGCTGCGCGGGCATCTGCGCATGACTGATACGAT
CGAGAACGAGCACTTTTTCGTACGTAAAAACGGCCTGCTATATGCCACGCCGCTGCTGCTGGTGCTGATTATGGTTGAGT
TCAGCGATGTGATCTTCGCCGTTGACAGTATTCCGGCGATCTTTGCGGTCACCACCGACCCGTTCATCGTACTGACCTCT
AACCTGTTTGCCATCTTAGGACTGCGCGCGATGTACTTCCTGCTGTCCGGCGTGGCGGAACGCTTCTCGATGCTGAAATA
TGGTCTGGCGGTCATTCTGGTCTTTATCGGCATTAAGATGCTGATCGTCGACTTCTACCATATTCCTATCGCGATTTCGC
TGGGCGTAGTGTTTGGCATTCTGACCATTACGCTGGTGATTAACACCTGGGTTAACCATCAGCGCGATAAGAAACTACGA
GCGCAATAA

Upstream 100 bases:

>100_bases
TATTGTTGTAAGTGAGACCTTGCCGAATGGCAAGGTCTATGCATAAAAGCAGCGGCTAATGCCATTCGGCATTAGCCGTT
TTTTTGCATGGGGAGAAATA

Downstream 100 bases:

>100_bases
TCTTTTATCGGGGTAAACCTGCCCCATCAAAAACGCCCGGCAGCGTACACCTGCCGGGCGTTTTTGTTTAACATGTCACA
ATACTGTTAATATAAAGTTA

Product: drug efflux protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 322; Mature: 322

Protein sequence:

>322_residues
MNTVGTPLLWGGFAVVVVIMLSIDLLLQGRRGAHAMSMKQAAGWSILWVTLSLLFNAAFWWYLAETQGREVADPQALAFL
TGYLIEKSLAVDNVFVWLMLFSYFSVPPALQRRVLVYGVLGAIVLRTIMIFAGTWLITQFEWLLYVFGAFLLFTGVKMAL
AKEDESGIGEKPMVRWLRGHLRMTDTIENEHFFVRKNGLLYATPLLLVLIMVEFSDVIFAVDSIPAIFAVTTDPFIVLTS
NLFAILGLRAMYFLLSGVAERFSMLKYGLAVILVFIGIKMLIVDFYHIPIAISLGVVFGILTITLVINTWVNHQRDKKLR
AQ

Sequences:

>Translated_322_residues
MNTVGTPLLWGGFAVVVVIMLSIDLLLQGRRGAHAMSMKQAAGWSILWVTLSLLFNAAFWWYLAETQGREVADPQALAFL
TGYLIEKSLAVDNVFVWLMLFSYFSVPPALQRRVLVYGVLGAIVLRTIMIFAGTWLITQFEWLLYVFGAFLLFTGVKMAL
AKEDESGIGEKPMVRWLRGHLRMTDTIENEHFFVRKNGLLYATPLLLVLIMVEFSDVIFAVDSIPAIFAVTTDPFIVLTS
NLFAILGLRAMYFLLSGVAERFSMLKYGLAVILVFIGIKMLIVDFYHIPIAISLGVVFGILTITLVINTWVNHQRDKKLR
AQ
>Mature_322_residues
MNTVGTPLLWGGFAVVVVIMLSIDLLLQGRRGAHAMSMKQAAGWSILWVTLSLLFNAAFWWYLAETQGREVADPQALAFL
TGYLIEKSLAVDNVFVWLMLFSYFSVPPALQRRVLVYGVLGAIVLRTIMIFAGTWLITQFEWLLYVFGAFLLFTGVKMAL
AKEDESGIGEKPMVRWLRGHLRMTDTIENEHFFVRKNGLLYATPLLLVLIMVEFSDVIFAVDSIPAIFAVTTDPFIVLTS
NLFAILGLRAMYFLLSGVAERFSMLKYGLAVILVFIGIKMLIVDFYHIPIAISLGVVFGILTITLVINTWVNHQRDKKLR
AQ

Specific function: Unknown

COG id: COG0861

COG function: function code P; Membrane protein TerC, possibly involved in tellurium resistance

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the terC family

Homologues:

Organism=Escherichia coli, GI48994922, Length=318, Percent_Identity=88.9937106918239, Blast_Score=580, Evalue=1e-167,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ALX_SALTI (Q8Z3L5)

Other databases:

- EMBL:   AL627278
- EMBL:   AE014613
- RefSeq:   NP_457613.1
- RefSeq:   NP_806825.1
- GeneID:   1069936
- GeneID:   1249665
- GenomeReviews:   AE014613_GR
- GenomeReviews:   AL513382_GR
- KEGG:   stt:t3144
- KEGG:   sty:STY3404
- HOGENOM:   HBG292583
- OMA:   YFAVPPA
- ProtClustDB:   CLSK880577
- BioCyc:   SENT209261:T3144-MONOMER
- BioCyc:   SENT220341:STY3404-MONOMER
- InterPro:   IPR005496
- InterPro:   IPR022369
- TIGRFAMs:   TIGR03718

Pfam domain/function: PF03741 TerC

EC number: NA

Molecular weight: Translated: 36224; Mature: 36224

Theoretical pI: Translated: 9.46; Mature: 9.46

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x116aff6c)-; HASH(0xff5055c)-; HASH(0x10e523a8)-; HASH(0x114208a4)-; HASH(0x11818978)-; HASH(0x113946dc)-; HASH(0x10bff154)-; HASH(0xfefe450)-; HASH(0xcde74dc)-;

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTVGTPLLWGGFAVVVVIMLSIDLLLQGRRGAHAMSMKQAAGWSILWVTLSLLFNAAFW
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHH
WYLAETQGREVADPQALAFLTGYLIEKSLAVDNVFVWLMLFSYFSVPPALQRRVLVYGVL
HHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
GAIVLRTIMIFAGTWLITQFEWLLYVFGAFLLFTGVKMALAKEDESGIGEKPMVRWLRGH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
LRMTDTIENEHFFVRKNGLLYATPLLLVLIMVEFSDVIFAVDSIPAIFAVTTDPFIVLTS
HHHHEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEHHH
NLFAILGLRAMYFLLSGVAERFSMLKYGLAVILVFIGIKMLIVDFYHIPIAISLGVVFGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTITLVINTWVNHQRDKKLRAQ
HHHHHHHHHHHCCCCCHHCCCH
>Mature Secondary Structure
MNTVGTPLLWGGFAVVVVIMLSIDLLLQGRRGAHAMSMKQAAGWSILWVTLSLLFNAAFW
CCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCHHHHHHHHHHHHHHHH
WYLAETQGREVADPQALAFLTGYLIEKSLAVDNVFVWLMLFSYFSVPPALQRRVLVYGVL
HHEECCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHH
GAIVLRTIMIFAGTWLITQFEWLLYVFGAFLLFTGVKMALAKEDESGIGEKPMVRWLRGH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHH
LRMTDTIENEHFFVRKNGLLYATPLLLVLIMVEFSDVIFAVDSIPAIFAVTTDPFIVLTS
HHHHEECCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEHHH
NLFAILGLRAMYFLLSGVAERFSMLKYGLAVILVFIGIKMLIVDFYHIPIAISLGVVFGI
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LTITLVINTWVNHQRDKKLRAQ
HHHHHHHHHHHCCCCCHHCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504