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The map label for this gene is gcp [H]

Identifier: 29143469

GI number: 29143469

Start: 3215809

End: 3216822

Strand: Reverse

Name: gcp [H]

Synonym: t3128

Alternate gene names: 29143469

Gene position: 3216822-3215809 (Counterclockwise)

Preceding gene: 29143473

Following gene: 29143467

Centisome position: 67.13

GC content: 57.69

Gene sequence:

>1014_bases
ATGCGTGTACTGGGTATTGAAACATCTTGCGATGAAACCGGCATCGCTATTTACGACGACAAAAAAGGTCTGTTAGCCAA
CCAATTGTATAGTCAGGTGAAATTACATGCTGATTACGGCGGCGTAGTGCCTGAACTGGCTTCCCGCGATCATGTGCGTA
AAACCGTGCCGCTGATTCAGGCGGCATTAAAAGAAGCCGCTCTGACGGCGAGCGATATCGACGCGGTGGCCTATACCGCA
GGCCCGGGCTTGGTCGGCGCGCTGCTGGTCGGCGCAACCGTCGGGCGTTCGCTGGCATTTGCCTGGAATGTGCCAGCCAT
TCCTGTACACCATATGGAAGGTCATCTGCTGGCGCCAATGCTGGAAGATAACCCTCCGGATTTCCCGTTTGTGGCGCTGC
TGGTCTCCGGCGGACATACGCAGCTCATTAGCGTGACCGGAATCGGTCAGTACGAACTGCTGGGAGAGTCGATTGACGAT
GCCGCCGGTGAAGCGTTTGATAAAACCGCCAAATTGTTGGGGCTGGATTATCCTGGCGGCCCGATGCTGTCGAAAATGGC
GTCGCAGGGGACGGCGGGGCGTTTTGTCTTTCCGCGCCCGATGACCGATCGCCCGGGGCTGGATTTTAGTTTTTCCGGTC
TGAAAACCTTTGCCGCTAACACCATTCGTAGTAATGGCGACGACGAACAAACTCGCGCTGATATCGCGCGCGCTTTTGAA
GATGCGGTCGTGGATACGCTGATGATCAAGTGCAAGCGCGCGCTGGAAAGCACCGGTTTTAAGCGTCTTGTCATGGCGGG
CGGCGTCAGCGCTAACCGCACGCTGCGTGCGAAGCTTGCCGAAATGATGCAAAAACGCCGCGGCGAAGTGTTCTATGCGC
GCCCGGAATTTTGTACCGACAACGGGGCGATGATCGCCTATGCCGGAATGGTGCGGTTTAAGGCGGGCGTTACGGCGGAT
CTTGGCGTAACGGTACGTCCGCGCTGGCCGCTGGCCGAGCTGCCGGCGGCGTAA

Upstream 100 bases:

>100_bases
TTTATAAGGGGAGGGAGTATACACGAAGTCGGGACTGAGGGTATACATCCACCCGCATTCGACCTACACTGCGCGGTATT
AGAGCGAGGTAAAACAAGTC

Downstream 100 bases:

>100_bases
AAGCGGAAAAAGGGGGCGACATCATGCCGCCCCAACGGATTTACAGCAAAACGATGGGCATCCACAACAGCCTGGAGACG
ATCAGCAGCACCAGGAAAAT

Product: DNA-binding/iron metalloprotein/AP endonuclease

Products: NA

Alternate protein names: Glycoprotease [H]

Number of amino acids: Translated: 337; Mature: 337

Protein sequence:

>337_residues
MRVLGIETSCDETGIAIYDDKKGLLANQLYSQVKLHADYGGVVPELASRDHVRKTVPLIQAALKEAALTASDIDAVAYTA
GPGLVGALLVGATVGRSLAFAWNVPAIPVHHMEGHLLAPMLEDNPPDFPFVALLVSGGHTQLISVTGIGQYELLGESIDD
AAGEAFDKTAKLLGLDYPGGPMLSKMASQGTAGRFVFPRPMTDRPGLDFSFSGLKTFAANTIRSNGDDEQTRADIARAFE
DAVVDTLMIKCKRALESTGFKRLVMAGGVSANRTLRAKLAEMMQKRRGEVFYARPEFCTDNGAMIAYAGMVRFKAGVTAD
LGVTVRPRWPLAELPAA

Sequences:

>Translated_337_residues
MRVLGIETSCDETGIAIYDDKKGLLANQLYSQVKLHADYGGVVPELASRDHVRKTVPLIQAALKEAALTASDIDAVAYTA
GPGLVGALLVGATVGRSLAFAWNVPAIPVHHMEGHLLAPMLEDNPPDFPFVALLVSGGHTQLISVTGIGQYELLGESIDD
AAGEAFDKTAKLLGLDYPGGPMLSKMASQGTAGRFVFPRPMTDRPGLDFSFSGLKTFAANTIRSNGDDEQTRADIARAFE
DAVVDTLMIKCKRALESTGFKRLVMAGGVSANRTLRAKLAEMMQKRRGEVFYARPEFCTDNGAMIAYAGMVRFKAGVTAD
LGVTVRPRWPLAELPAA
>Mature_337_residues
MRVLGIETSCDETGIAIYDDKKGLLANQLYSQVKLHADYGGVVPELASRDHVRKTVPLIQAALKEAALTASDIDAVAYTA
GPGLVGALLVGATVGRSLAFAWNVPAIPVHHMEGHLLAPMLEDNPPDFPFVALLVSGGHTQLISVTGIGQYELLGESIDD
AAGEAFDKTAKLLGLDYPGGPMLSKMASQGTAGRFVFPRPMTDRPGLDFSFSGLKTFAANTIRSNGDDEQTRADIARAFE
DAVVDTLMIKCKRALESTGFKRLVMAGGVSANRTLRAKLAEMMQKRRGEVFYARPEFCTDNGAMIAYAGMVRFKAGVTAD
LGVTVRPRWPLAELPAA

Specific function: Could Be A Metalloprotease. [C]

COG id: COG0533

COG function: function code O; Metal-dependent proteases with possible chaperone activity

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M22 family [H]

Homologues:

Organism=Homo sapiens, GI116812636, Length=355, Percent_Identity=34.3661971830986, Blast_Score=186, Evalue=2e-47,
Organism=Homo sapiens, GI8923380, Length=332, Percent_Identity=35.5421686746988, Blast_Score=159, Evalue=3e-39,
Organism=Escherichia coli, GI1789445, Length=337, Percent_Identity=95.2522255192878, Blast_Score=660, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17557464, Length=327, Percent_Identity=31.8042813455657, Blast_Score=167, Evalue=8e-42,
Organism=Caenorhabditis elegans, GI71995670, Length=329, Percent_Identity=34.6504559270517, Blast_Score=149, Evalue=2e-36,
Organism=Saccharomyces cerevisiae, GI6320099, Length=368, Percent_Identity=33.1521739130435, Blast_Score=172, Evalue=9e-44,
Organism=Saccharomyces cerevisiae, GI6322891, Length=361, Percent_Identity=27.4238227146814, Blast_Score=123, Evalue=4e-29,
Organism=Drosophila melanogaster, GI20129063, Length=338, Percent_Identity=35.7988165680473, Blast_Score=189, Evalue=3e-48,
Organism=Drosophila melanogaster, GI21357207, Length=329, Percent_Identity=31.306990881459, Blast_Score=162, Evalue=2e-40,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR022450
- InterPro:   IPR000905
- InterPro:   IPR017860
- InterPro:   IPR017861 [H]

Pfam domain/function: PF00814 Peptidase_M22 [H]

EC number: =3.4.24.57 [H]

Molecular weight: Translated: 35999; Mature: 35999

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS01016 GLYCOPROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVLGIETSCDETGIAIYDDKKGLLANQLYSQVKLHADYGGVVPELASRDHVRKTVPLIQ
CEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHEEECCCCCCCHHHHCHHHHHHHHHHHH
AALKEAALTASDIDAVAYTAGPGLVGALLVGATVGRSLAFAWNVPAIPVHHMEGHLLAPM
HHHHHHHCCHHCCCEEEEECCCHHHHHHHHHHHHCCCEEEEECCCCCEEECCCCCEECCH
LEDNPPDFPFVALLVSGGHTQLISVTGIGQYELLGESIDDAAGEAFDKTAKLLGLDYPGG
HCCCCCCCCEEEEEECCCCEEEEEEECCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCC
PMLSKMASQGTAGRFVFPRPMTDRPGLDFSFSGLKTFAANTIRSNGDDEQTRADIARAFE
HHHHHHHCCCCCCCEECCCCCCCCCCCCEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
DAVVDTLMIKCKRALESTGFKRLVMAGGVSANRTLRAKLAEMMQKRRGEVFYARPEFCTD
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEECCCEECC
NGAMIAYAGMVRFKAGVTADLGVTVRPRWPLAELPAA
CCCEEEEEHHHHHHCCCCEECCEEECCCCCHHCCCCC
>Mature Secondary Structure
MRVLGIETSCDETGIAIYDDKKGLLANQLYSQVKLHADYGGVVPELASRDHVRKTVPLIQ
CEEEECCCCCCCCCEEEEECCCCHHHHHHHHHHEEECCCCCCCHHHHCHHHHHHHHHHHH
AALKEAALTASDIDAVAYTAGPGLVGALLVGATVGRSLAFAWNVPAIPVHHMEGHLLAPM
HHHHHHHCCHHCCCEEEEECCCHHHHHHHHHHHHCCCEEEEECCCCCEEECCCCCEECCH
LEDNPPDFPFVALLVSGGHTQLISVTGIGQYELLGESIDDAAGEAFDKTAKLLGLDYPGG
HCCCCCCCCEEEEEECCCCEEEEEEECCCHHHHHCCHHHHHHHHHHHHHHHHHCCCCCCC
PMLSKMASQGTAGRFVFPRPMTDRPGLDFSFSGLKTFAANTIRSNGDDEQTRADIARAFE
HHHHHHHCCCCCCCEECCCCCCCCCCCCEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
DAVVDTLMIKCKRALESTGFKRLVMAGGVSANRTLRAKLAEMMQKRRGEVFYARPEFCTD
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHHCCCEEEECCCEECC
NGAMIAYAGMVRFKAGVTADLGVTVRPRWPLAELPAA
CCCEEEEEHHHHHHCCCCEECCEEECCCCCHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA