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The map label for this gene is steT [H]

Identifier: 29143392

GI number: 29143392

Start: 3126758

End: 3128257

Strand: Reverse

Name: steT [H]

Synonym: t3048

Alternate gene names: 29143392

Gene position: 3128257-3126758 (Counterclockwise)

Preceding gene: 29143393

Following gene: 29143391

Centisome position: 65.28

GC content: 51.93

Gene sequence:

>1500_bases
ATGTTTAAAAACAGACTTGCCAGCCATCTTGAACGTGGCGTTATTGGTTTCCCCACGACGCTTGCCAGCTCCGTCGGGCT
GATTATGGCAAGCCCGGTGATCCTGACCGTGACCAGTGGTTTTGGCTCAGGGGGAGATACCTTTGCCCTTGCGGTATTAC
TGGCATTTATTATGATGCAAGCGCAGATTACCACCTTTGCCGAAGCGGCAACGCTCATTCCCACGACTGGCTCCGTCTAC
GACTATATCTCCTGCGGGATGGGGCGTTTTTTCGCTATCACCGGTGCGCTTTGCGCTTACCTGATCGTACACATTTTTGC
CGGCACGGCAGAAACGATTCTCGCTGGCGTCATGGCGCTGGTGAACTTTGAGTCCGTTAGCGAACACGTGGCCATGCAGC
ACAATACCTGGATGGTTGGCGTCGGCATGGTAGTGGTTTTCGGGATACTGAATGCCATTGGTGTTGAAGTATTTGGCAAG
GTGGAAGTGTTTCTTACATTCGGTATGTGGACTACCCTGACCATCTTCGGTTTATGCGGGATCCTGTTATCCCCGGTCAC
TCATCATTCCGGGTGGTTTGGCGCACCGCTTGATGTCAGTAATCTTTCTGGTCTGTTTGGTTATATAGGCATGGCGATGT
TTATGTTCGTCGGTTGTGAACTGGTCACGCCAATGGCGCCGGAAATTAAAAAAGCGCATCGTACGATTCCCAGAGCGATG
GCGCTTGGCCTTTTAGCGGTGGCAGGTTGTATGTTCCTCTATGGCGCTGCGATTAACCGGCAGGTAAATAATGTGGTGGT
CGATGCGGCAAACCATATCTTTTTACTGGATACGCCGATGGCTATTCCCGCCTTTGCCAATCGTGTCATGGGACATGTCG
GGCAATACTGGCTGGGCGTGGGGTTGTTGTTAGCGGGATGTGCGACGATTAATACGCTAATGGCGGCAGTACCGCGTATT
ATATACGGCATGGCGCTGGACGGCGCTTTGCCGCGGTTTCTGACCTGGTTGCACCCCCGCTTTAAAACACCGGTCATCGC
CATCGCATTCGGTGTTGCGATTCCCTGTTTACATGCCTGGTATCTGAACGGTGATATCGACCACATTGTTCCGCTGATCC
TCGCTGCGGTCTGCGCCTGGGGAGTAGCTTATCTGCTGGTAACGTTATCGGTCGTTATCTTACGTATTCGGCGCCCCGAT
TTACCACGCGCTTACCGGGCCCCCTGGTTTCCCTTACCTCAGATTATTTCGAGCGTGGGTATTATTATCGCCATTATTAA
TATCGCGCCTCCAGGAATGAACAGTCGGGATGTACTTATACCATTCGGTATTATGCTTGGATTGACTGCCGCCTATGCCT
TATTCTGGACATTATGTGTGCAACGGGTTAATCCTTTCCTCCCGCTTCCGGTAGAAGAGGTCGTGGAACGGGCGATGGGC
AATTATGAAAAGCGAAACAATGAAGAGATGACGCCAGATGTCCTCCGTCCCCTGGTTTAA

Upstream 100 bases:

>100_bases
CCCTCTTCAGGACGATACCTGTTAGATGCGCTGCCTGCCATAAATAAGCGTTATTCCGGAGCGGTAATTTATTGTTGTAA
TAATAGTGAAGAGGTTGACC

Downstream 100 bases:

>100_bases
GAACGCATTAATGAATATGGTGTTACGTGATTTGAGCGGCTGGCGTTGTGAAAAATTGACCGAACATAGCGCCGTGCTGC
ATCTGAATGCATTTACCCAG

Product: amino acid ABC transporter

Products: Proton [Cytoplasm]; L-proline [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 499; Mature: 499

Protein sequence:

>499_residues
MFKNRLASHLERGVIGFPTTLASSVGLIMASPVILTVTSGFGSGGDTFALAVLLAFIMMQAQITTFAEAATLIPTTGSVY
DYISCGMGRFFAITGALCAYLIVHIFAGTAETILAGVMALVNFESVSEHVAMQHNTWMVGVGMVVVFGILNAIGVEVFGK
VEVFLTFGMWTTLTIFGLCGILLSPVTHHSGWFGAPLDVSNLSGLFGYIGMAMFMFVGCELVTPMAPEIKKAHRTIPRAM
ALGLLAVAGCMFLYGAAINRQVNNVVVDAANHIFLLDTPMAIPAFANRVMGHVGQYWLGVGLLLAGCATINTLMAAVPRI
IYGMALDGALPRFLTWLHPRFKTPVIAIAFGVAIPCLHAWYLNGDIDHIVPLILAAVCAWGVAYLLVTLSVVILRIRRPD
LPRAYRAPWFPLPQIISSVGIIIAIINIAPPGMNSRDVLIPFGIMLGLTAAYALFWTLCVQRVNPFLPLPVEEVVERAMG
NYEKRNNEEMTPDVLRPLV

Sequences:

>Translated_499_residues
MFKNRLASHLERGVIGFPTTLASSVGLIMASPVILTVTSGFGSGGDTFALAVLLAFIMMQAQITTFAEAATLIPTTGSVY
DYISCGMGRFFAITGALCAYLIVHIFAGTAETILAGVMALVNFESVSEHVAMQHNTWMVGVGMVVVFGILNAIGVEVFGK
VEVFLTFGMWTTLTIFGLCGILLSPVTHHSGWFGAPLDVSNLSGLFGYIGMAMFMFVGCELVTPMAPEIKKAHRTIPRAM
ALGLLAVAGCMFLYGAAINRQVNNVVVDAANHIFLLDTPMAIPAFANRVMGHVGQYWLGVGLLLAGCATINTLMAAVPRI
IYGMALDGALPRFLTWLHPRFKTPVIAIAFGVAIPCLHAWYLNGDIDHIVPLILAAVCAWGVAYLLVTLSVVILRIRRPD
LPRAYRAPWFPLPQIISSVGIIIAIINIAPPGMNSRDVLIPFGIMLGLTAAYALFWTLCVQRVNPFLPLPVEEVVERAMG
NYEKRNNEEMTPDVLRPLV
>Mature_499_residues
MFKNRLASHLERGVIGFPTTLASSVGLIMASPVILTVTSGFGSGGDTFALAVLLAFIMMQAQITTFAEAATLIPTTGSVY
DYISCGMGRFFAITGALCAYLIVHIFAGTAETILAGVMALVNFESVSEHVAMQHNTWMVGVGMVVVFGILNAIGVEVFGK
VEVFLTFGMWTTLTIFGLCGILLSPVTHHSGWFGAPLDVSNLSGLFGYIGMAMFMFVGCELVTPMAPEIKKAHRTIPRAM
ALGLLAVAGCMFLYGAAINRQVNNVVVDAANHIFLLDTPMAIPAFANRVMGHVGQYWLGVGLLLAGCATINTLMAAVPRI
IYGMALDGALPRFLTWLHPRFKTPVIAIAFGVAIPCLHAWYLNGDIDHIVPLILAAVCAWGVAYLLVTLSVVILRIRRPD
LPRAYRAPWFPLPQIISSVGIIIAIINIAPPGMNSRDVLIPFGIMLGLTAAYALFWTLCVQRVNPFLPLPVEEVVERAMG
NYEKRNNEEMTPDVLRPLV

Specific function: Exhibits an obligate exchange activity for serine, threonine and aromatic amino acids [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the amino acid-polyamine-organocation (APC) superfamily. L-type amino acid transporter (LAT) (TC 2.A.3.8) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004841
- InterPro:   IPR002293 [H]

Pfam domain/function: PF00324 AA_permease [H]

EC number: NA

Molecular weight: Translated: 53814; Mature: 53814

Theoretical pI: Translated: 7.54; Mature: 7.54

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
6.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFKNRLASHLERGVIGFPTTLASSVGLIMASPVILTVTSGFGSGGDTFALAVLLAFIMMQ
CCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHHH
AQITTFAEAATLIPTTGSVYDYISCGMGRFFAITGALCAYLIVHIFAGTAETILAGVMAL
HHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
VNFESVSEHVAMQHNTWMVGVGMVVVFGILNAIGVEVFGKVEVFLTFGMWTTLTIFGLCG
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILLSPVTHHSGWFGAPLDVSNLSGLFGYIGMAMFMFVGCELVTPMAPEIKKAHRTIPRAM
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
ALGLLAVAGCMFLYGAAINRQVNNVVVDAANHIFLLDTPMAIPAFANRVMGHVGQYWLGV
HHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHH
GLLLAGCATINTLMAAVPRIIYGMALDGALPRFLTWLHPRFKTPVIAIAFGVAIPCLHAW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCHHHHHHHHHHHHHHHH
YLNGDIDHIVPLILAAVCAWGVAYLLVTLSVVILRIRRPDLPRAYRAPWFPLPQIISSVG
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCHHHHHHHHH
IIIAIINIAPPGMNSRDVLIPFGIMLGLTAAYALFWTLCVQRVNPFLPLPVEEVVERAMG
HHHHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHC
NYEKRNNEEMTPDVLRPLV
CHHHCCCCCCCHHHHCCCC
>Mature Secondary Structure
MFKNRLASHLERGVIGFPTTLASSVGLIMASPVILTVTSGFGSGGDTFALAVLLAFIMMQ
CCHHHHHHHHHCCCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCCHHHHHHHHHHHHHHH
AQITTFAEAATLIPTTGSVYDYISCGMGRFFAITGALCAYLIVHIFAGTAETILAGVMAL
HHHHHHHHHHHHCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
VNFESVSEHVAMQHNTWMVGVGMVVVFGILNAIGVEVFGKVEVFLTFGMWTTLTIFGLCG
HHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILLSPVTHHSGWFGAPLDVSNLSGLFGYIGMAMFMFVGCELVTPMAPEIKKAHRTIPRAM
HHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHH
ALGLLAVAGCMFLYGAAINRQVNNVVVDAANHIFLLDTPMAIPAFANRVMGHVGQYWLGV
HHHHHHHHHHHHHHHHHHHHHHHHHEEECCCEEEEEECCCHHHHHHHHHHHHHHHHHHHH
GLLLAGCATINTLMAAVPRIIYGMALDGALPRFLTWLHPRFKTPVIAIAFGVAIPCLHAW
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCHHHHHHHHHHHHHHHH
YLNGDIDHIVPLILAAVCAWGVAYLLVTLSVVILRIRRPDLPRAYRAPWFPLPQIISSVG
HCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCCCCCHHHHHHHHH
IIIAIINIAPPGMNSRDVLIPFGIMLGLTAAYALFWTLCVQRVNPFLPLPVEEVVERAMG
HHHHHEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHC
NYEKRNNEEMTPDVLRPLV
CHHHCCCCCCCHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; L-proline [Periplasm] [C]

Specific reaction: Proton [Periplasm] + L-proline [Periplasm] = Proton [Cytoplasm] + L-proline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]