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The map label for this gene is cbiO1 [H]

Identifier: 29143343

GI number: 29143343

Start: 3083747

End: 3084430

Strand: Direct

Name: cbiO1 [H]

Synonym: t2993

Alternate gene names: 29143343

Gene position: 3083747-3084430 (Clockwise)

Preceding gene: 29143342

Following gene: 29143344

Centisome position: 64.35

GC content: 55.99

Gene sequence:

>684_bases
ATGGATATGGTTACGTTAGAGCAGTTTCGTTATCTTCCGTCCGATGCGACACGCCCGCCGGCATGTTTTGATTTCCACTA
TTCAACACCCGGAATAGTGGCGATAGTCGGCGATAACGGCAGCGGAAAAAGTACGCTGGCGCAACTGATGGCTGGCTGGT
ATCCGGATTATCTCCCCGGCGATATTGACGGCACAGGCCTACTGCTTGGCGTACCTATCGGGCGGCTCCCGCTGGTAGAA
CAGTCGCCCACCATCCACCTGGTGCAGCAATCGCCTTATTTACAGCTTTCCGGCTGTACCTTTAGCGTAGAGGAAGAGGT
GGCGTTTGGCCCGGAGAATCTCGGCCTCCATGAAGCGGAAATTCTACGGCGCATTGACGAGGCGCTGACTCTGACAAACT
GCCAGTCGTTACGCCATCGCCATCCCGGCACGCTCTCCGGCGGCGAAACGCAGCGGGTAGTGATTGCCAGCGCGCTTGCC
ATGCAGCCCAGATTATTAGTTCTTGATGAAGCCTTCAGTCGGCTGACGTCAGCGGCCACCGGGACACTGCTGGAACGGTT
ACAACAGTGGGCGCTGGAACGTCATTCTCTCATTGTGCTTTTTGAGCGTAATCATTTCCCCTTTCTGACGCGATGCCAGC
GGGTATGGCAATTGCGCAACGGAGCGCTAACCCCATTATGTTGA

Upstream 100 bases:

>100_bases
TGCATCGAGCCCGAACCACGCTGTGGGCGCCGAAAGATAGCATGTTACAACGGGTTGCGCGGTATGGCATGGTACTGCTA
ATACTGGCGGAAGCGGGAGT

Downstream 100 bases:

>100_bases
CGTTAAATCAGGTCGCTTATCGCTGGCCAGATGCCGCAGCCGACTGTCTGCACGCCATCTCGCTTGAACTTCGTGACGGC
GAATGGCTGGCGTTGACCGG

Product: ABC transporter ATP-binding protein

Products: ADP; phosphate; putrescine [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 227; Mature: 227

Protein sequence:

>227_residues
MDMVTLEQFRYLPSDATRPPACFDFHYSTPGIVAIVGDNGSGKSTLAQLMAGWYPDYLPGDIDGTGLLLGVPIGRLPLVE
QSPTIHLVQQSPYLQLSGCTFSVEEEVAFGPENLGLHEAEILRRIDEALTLTNCQSLRHRHPGTLSGGETQRVVIASALA
MQPRLLVLDEAFSRLTSAATGTLLERLQQWALERHSLIVLFERNHFPFLTRCQRVWQLRNGALTPLC

Sequences:

>Translated_227_residues
MDMVTLEQFRYLPSDATRPPACFDFHYSTPGIVAIVGDNGSGKSTLAQLMAGWYPDYLPGDIDGTGLLLGVPIGRLPLVE
QSPTIHLVQQSPYLQLSGCTFSVEEEVAFGPENLGLHEAEILRRIDEALTLTNCQSLRHRHPGTLSGGETQRVVIASALA
MQPRLLVLDEAFSRLTSAATGTLLERLQQWALERHSLIVLFERNHFPFLTRCQRVWQLRNGALTPLC
>Mature_227_residues
MDMVTLEQFRYLPSDATRPPACFDFHYSTPGIVAIVGDNGSGKSTLAQLMAGWYPDYLPGDIDGTGLLLGVPIGRLPLVE
QSPTIHLVQQSPYLQLSGCTFSVEEEVAFGPENLGLHEAEILRRIDEALTLTNCQSLRHRHPGTLSGGETQRVVIASALA
MQPRLLVLDEAFSRLTSAATGTLLERLQQWALERHSLIVLFERNHFPFLTRCQRVWQLRNGALTPLC

Specific function: Part of the ABC transporter complex CbiONQ involved in cobalt import. Responsible for energy coupling to the transport system [H]

COG id: COG1122

COG function: function code P; ABC-type cobalt transport system, ATPase component

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transporter domain [H]

Homologues:

Organism=Homo sapiens, GI42741659, Length=178, Percent_Identity=35.9550561797753, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI4505771, Length=178, Percent_Identity=33.1460674157303, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI9961252, Length=178, Percent_Identity=33.1460674157303, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI9961250, Length=181, Percent_Identity=33.7016574585635, Blast_Score=70, Evalue=2e-12,
Organism=Escherichia coli, GI87081791, Length=166, Percent_Identity=33.7349397590361, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1787370, Length=220, Percent_Identity=29.5454545454545, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1789891, Length=200, Percent_Identity=32.5, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1787029, Length=181, Percent_Identity=30.3867403314917, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1789032, Length=197, Percent_Identity=29.4416243654822, Blast_Score=67, Evalue=8e-13,
Organism=Escherichia coli, GI1786653, Length=225, Percent_Identity=28.8888888888889, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786398, Length=228, Percent_Identity=29.3859649122807, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI1786563, Length=187, Percent_Identity=31.5508021390374, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1788450, Length=173, Percent_Identity=31.2138728323699, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI87081709, Length=162, Percent_Identity=28.3950617283951, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1787792, Length=203, Percent_Identity=29.5566502463054, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1788761, Length=162, Percent_Identity=29.6296296296296, Blast_Score=64, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17543740, Length=205, Percent_Identity=33.1707317073171, Blast_Score=80, Evalue=7e-16,
Organism=Caenorhabditis elegans, GI17565938, Length=179, Percent_Identity=34.0782122905028, Blast_Score=74, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17567265, Length=193, Percent_Identity=33.160621761658, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17533971, Length=178, Percent_Identity=32.5842696629214, Blast_Score=74, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI115534520, Length=233, Percent_Identity=28.755364806867, Blast_Score=70, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17541710, Length=172, Percent_Identity=33.7209302325581, Blast_Score=70, Evalue=8e-13,
Organism=Caenorhabditis elegans, GI17567269, Length=174, Percent_Identity=34.4827586206897, Blast_Score=70, Evalue=9e-13,
Organism=Caenorhabditis elegans, GI115535101, Length=174, Percent_Identity=33.3333333333333, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17569143, Length=178, Percent_Identity=31.4606741573034, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17569145, Length=178, Percent_Identity=30.3370786516854, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI212646699, Length=200, Percent_Identity=29.5, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193211017, Length=202, Percent_Identity=29.7029702970297, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193211015, Length=202, Percent_Identity=29.7029702970297, Blast_Score=66, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71996809, Length=202, Percent_Identity=29.7029702970297, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24653245, Length=201, Percent_Identity=31.3432835820896, Blast_Score=68, Evalue=4e-12,
Organism=Drosophila melanogaster, GI281363262, Length=201, Percent_Identity=31.3432835820896, Blast_Score=68, Evalue=5e-12,
Organism=Drosophila melanogaster, GI17136662, Length=203, Percent_Identity=33.4975369458128, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28574744, Length=176, Percent_Identity=27.8409090909091, Blast_Score=66, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR015856
- InterPro:   IPR003593
- InterPro:   IPR022112 [H]

Pfam domain/function: PF00005 ABC_tran; PF12370 CoABC_C [H]

EC number: NA

Molecular weight: Translated: 25150; Mature: 25150

Theoretical pI: Translated: 5.87; Mature: 5.87

Prosite motif: PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDMVTLEQFRYLPSDATRPPACFDFHYSTPGIVAIVGDNGSGKSTLAQLMAGWYPDYLPG
CCCEEHHHHHCCCCCCCCCCCEEEEECCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCC
DIDGTGLLLGVPIGRLPLVEQSPTIHLVQQSPYLQLSGCTFSVEEEVAFGPENLGLHEAE
CCCCCEEEEECCCCCCCCCCCCCCEEEEECCCCEEEECCEEEECHHHHCCCCCCCCCHHH
ILRRIDEALTLTNCQSLRHRHPGTLSGGETQRVVIASALAMQPRLLVLDEAFSRLTSAAT
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCEEEHHHHHHHHHHHHHH
GTLLERLQQWALERHSLIVLFERNHFPFLTRCQRVWQLRNGALTPLC
HHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MDMVTLEQFRYLPSDATRPPACFDFHYSTPGIVAIVGDNGSGKSTLAQLMAGWYPDYLPG
CCCEEHHHHHCCCCCCCCCCCEEEEECCCCCEEEEECCCCCCHHHHHHHHHHCCCCCCCC
DIDGTGLLLGVPIGRLPLVEQSPTIHLVQQSPYLQLSGCTFSVEEEVAFGPENLGLHEAE
CCCCCEEEEECCCCCCCCCCCCCCEEEEECCCCEEEECCEEEECHHHHCCCCCCCCCHHH
ILRRIDEALTLTNCQSLRHRHPGTLSGGETQRVVIASALAMQPRLLVLDEAFSRLTSAAT
HHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCEEEHHHHHHHHHHHHHH
GTLLERLQQWALERHSLIVLFERNHFPFLTRCQRVWQLRNGALTPLC
HHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; putrescine [Periplasm]; H2O [C]

Specific reaction: ATP + putrescine [Periplasm] + H2O = ADP + phosphate + putrescine [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA