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The map label for this gene is fucR [H]

Identifier: 29143241

GI number: 29143241

Start: 2973429

End: 2974139

Strand: Direct

Name: fucR [H]

Synonym: t2887

Alternate gene names: 29143241

Gene position: 2973429-2974139 (Clockwise)

Preceding gene: 29143240

Following gene: 29143246

Centisome position: 62.05

GC content: 49.93

Gene sequence:

>711_bases
ATGAAAGCGGCACGCCAACAAGCGATAGTCGATCTGCTGATCAATCATAAAAGTCTGACCACCGAAGCGCTGGCCACCCG
GCTTAACGTCAGTAAAGAGACCATCCGCCGCGATCTCAGTGAACTACAGACGCAGGGAAAAGTGCTGCGTAATCACGGAC
GAGCTAAATATATTCATCGTGAAAATCAGGACAGCGGCGATCCATTCCATATCCGCCTGAAAAGCCATTATGCGCATAAA
GCCGATATTGCCCGTGAAGCGTTAGCGTGGATAGAAGAAGGAATGACGATTGCGCTGGATGCCAGTTCAACCTGCTGGTA
TCTGGCCCGCCAGTTGCCGGATATTCCCATTCAGGTTTTTACCAATAGCCATCCTATCTGTCAGGAGCTGGGAAAACGCG
AACGCATTGCGCTGATAAGTTCCGGCGGCCAGCTTGAACGTAAATATGGCTGTTACGTTAATCCGTCGCTTATCTCACAG
CTAAAATCGCTTGATATCGATCTGTTCATCTTTTCCTGCGAGGGGATCGACGGCGGCGGCGATCTGTGGGACTCCAATGC
GATCAACGCCGATTTTAAATCTATCCTGCTCAGGCGCGCCTCGCAGTCTTTATTATTGATTGATAAAAGTAAATTTAATC
GTTCAGGAGAGGCGCGCATCGGCCATCTGGATGATGTGACGCATATCGTTTCAGATGCGCCGCAGTCATAG

Upstream 100 bases:

>100_bases
GAAGTACGGAAATATTCTTTTAAAAAAAGGGGTAACGCCGTAATCTCTTGCCGGTGCGCCCGCATGACGCGGGCGTTCAT
CGAATGATGGGGTGAGAAAA

Downstream 100 bases:

>100_bases
GCCGGATAAGCGTGCGCCATCCGGCGCTGATGACGCGCCGGATGACGGCAGCGCGTTTTTATCGCTCGTCGCGACGTCCG
CCAACAGCCGCCCACAACCG

Product: DNA-binding transcriptional activator FucR

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 236; Mature: 236

Protein sequence:

>236_residues
MKAARQQAIVDLLINHKSLTTEALATRLNVSKETIRRDLSELQTQGKVLRNHGRAKYIHRENQDSGDPFHIRLKSHYAHK
ADIAREALAWIEEGMTIALDASSTCWYLARQLPDIPIQVFTNSHPICQELGKRERIALISSGGQLERKYGCYVNPSLISQ
LKSLDIDLFIFSCEGIDGGGDLWDSNAINADFKSILLRRASQSLLLIDKSKFNRSGEARIGHLDDVTHIVSDAPQS

Sequences:

>Translated_236_residues
MKAARQQAIVDLLINHKSLTTEALATRLNVSKETIRRDLSELQTQGKVLRNHGRAKYIHRENQDSGDPFHIRLKSHYAHK
ADIAREALAWIEEGMTIALDASSTCWYLARQLPDIPIQVFTNSHPICQELGKRERIALISSGGQLERKYGCYVNPSLISQ
LKSLDIDLFIFSCEGIDGGGDLWDSNAINADFKSILLRRASQSLLLIDKSKFNRSGEARIGHLDDVTHIVSDAPQS
>Mature_236_residues
MKAARQQAIVDLLINHKSLTTEALATRLNVSKETIRRDLSELQTQGKVLRNHGRAKYIHRENQDSGDPFHIRLKSHYAHK
ADIAREALAWIEEGMTIALDASSTCWYLARQLPDIPIQVFTNSHPICQELGKRERIALISSGGQLERKYGCYVNPSLISQ
LKSLDIDLFIFSCEGIDGGGDLWDSNAINADFKSILLRRASQSLLLIDKSKFNRSGEARIGHLDDVTHIVSDAPQS

Specific function: Transcriptional activator of the fuc operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789170, Length=235, Percent_Identity=88.936170212766, Blast_Score=439, Evalue=1e-125,
Organism=Escherichia coli, GI1788069, Length=229, Percent_Identity=31.4410480349345, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1789829, Length=234, Percent_Identity=27.3504273504274, Blast_Score=100, Evalue=1e-22,
Organism=Escherichia coli, GI87082344, Length=229, Percent_Identity=26.6375545851528, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1790635, Length=231, Percent_Identity=23.3766233766234, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1789059, Length=231, Percent_Identity=26.4069264069264, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1790753, Length=230, Percent_Identity=22.6086956521739, Blast_Score=69, Evalue=3e-13,
Organism=Escherichia coli, GI1787540, Length=243, Percent_Identity=27.5720164609054, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1789519, Length=231, Percent_Identity=25.974025974026, Blast_Score=67, Evalue=1e-12,
Organism=Escherichia coli, GI226510968, Length=236, Percent_Identity=25.4237288135593, Blast_Score=65, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 26444; Mature: 26444

Theoretical pI: Translated: 8.02; Mature: 8.02

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAARQQAIVDLLINHKSLTTEALATRLNVSKETIRRDLSELQTQGKVLRNHGRAKYIHR
CCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEC
ENQDSGDPFHIRLKSHYAHKADIAREALAWIEEGMTIALDASSTCWYLARQLPDIPIQVF
CCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHCCCCCEEEE
TNSHPICQELGKRERIALISSGGQLERKYGCYVNPSLISQLKSLDIDLFIFSCEGIDGGG
CCCCHHHHHCCCCCEEEEEECCCCCCCCCCCEECHHHHHHHHHCCEEEEEEEECCCCCCC
DLWDSNAINADFKSILLRRASQSLLLIDKSKFNRSGEARIGHLDDVTHIVSDAPQS
CCCCCCCCCHHHHHHHHHHCCCCEEEEEHHHCCCCCCCCCCCHHHHHHHHHCCCCC
>Mature Secondary Structure
MKAARQQAIVDLLINHKSLTTEALATRLNVSKETIRRDLSELQTQGKVLRNHGRAKYIHR
CCHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCEEEEEC
ENQDSGDPFHIRLKSHYAHKADIAREALAWIEEGMTIALDASSTCWYLARQLPDIPIQVF
CCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHCCCCCEEEE
TNSHPICQELGKRERIALISSGGQLERKYGCYVNPSLISQLKSLDIDLFIFSCEGIDGGG
CCCCHHHHHCCCCCEEEEEECCCCCCCCCCCEECHHHHHHHHHCCEEEEEEEECCCCCCC
DLWDSNAINADFKSILLRRASQSLLLIDKSKFNRSGEARIGHLDDVTHIVSDAPQS
CCCCCCCCCHHHHHHHHHHCCCCEEEEEHHHCCCCCCCCCCCHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2664711; 9278503 [H]