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The map label for this gene is fucK

Identifier: 29143239

GI number: 29143239

Start: 2971529

End: 2972947

Strand: Direct

Name: fucK

Synonym: t2885

Alternate gene names: 29143239

Gene position: 2971529-2972947 (Clockwise)

Preceding gene: 29143238

Following gene: 29143240

Centisome position: 62.01

GC content: 58.56

Gene sequence:

>1419_bases
ATGAAACAAGACGTTATCCTGGTTCTCGACTGCGGTGCGACTAACGTTCGGGCGATCGCCGTTGATCGCCAGGGGAAAAT
TGTCGCCCGCGCCTCAACCGCTAACGCCAGCGACATTGCCGCAGAAAATAGCGCCTGGCATCAGTGGTCGCTGGACGCCA
TCCTGCAACGTTTCGCCGACTGCTGCAGGTCACTCTCCAGCGCCCTGTCGGAGTGTGTTGTTCGCGGTATTACGGTGACT
ACTTTCGGCGTCGATGGCGCGCTGGTCGATGCGCAGGGTAAGCTGCTCTACCCGGTCATCAGTTGGAAATGCCCGCGAAC
CGCTGCCGTGATGGAAACGATTGAGCGCTTTATCTCGCCCCGGCAATTGCAGACGCTCTCCGGCGTCGGCGCGTTCAGCT
TTAACACGCTGTATAAACTGGTCTGGCTTAAAGAGAATCATCCGCGCCTGCTGGAACAAGCTCACTGCTGGCTGTTTATC
TCGTCGCTGATTAACCACCGTCTGACCGGAGAGTTTACGACCGATATCACTATGGCAGGCACCAGCCAGCTACTGGATAT
CCATCAGCGCGACTTTAGTCCGGAAATCCTGCAGGCGACGGGCCTGGCGCGCCGCCTGTTCCCGCGTATCGTGGAAGCGG
GCGCCCCGATAGGCACGCTACAGACAGACGCGGCCAGGCTACTCGGTCTCCCGGCGGGTGTGCCAGTGATCTCTGCCGAA
CACGATACTCAGTTCGCGTTATTCGGCGCTGGCGCGCAGCAAGGTGAACCAGTGCTCTCCTCCGGAACATGGGAGATTCT
GATGGTGCGCAGCGGTCAGGTGGATACCTCGCTGCTCAGTCAGTATCCGGGCTCGACCTGTGAACTGGACAGTCAGTCGG
GGCTTTATAACCCCGGAATGCAGTGGCTGGCCTCCGGCGTACTCGAATGGGTACGAAAACTGCTGTGGACGCCGGAAACG
CCATGGCAAACGCTGATCGACGAAGCGCGCGCTATTCCCGCTGGCGCGGAAGGCGTGCGGATGCAGTGCGATCTGCTCGC
CTGTCAAAATGCAGGCTGGCAGGGCGTGACGCTCAATACCACCCGCGGCCATTTCTATCGCGCCGCGCTGGAAGGCCTGA
CGGCGCAACTTCAGCGTAATCTGCGCACGCTGGAGAAAATCGGCCATTTTAACGCCACAGAACTGTTACTGGTTGGCGGC
GGCAGTCGCAACGCTTTGTGGAATCAAATTAAAGCGAATCAACTTGATATCCCTATCAAAGTGCTGGACGACGCGGAAAC
CACCGTGGCCGGCGCTGCCATGTTTGGCTGGTACGGCGTAGGCGAATTTAGTAGCCCGGAGCAGGCGCGTGCGCAGGTCA
ATTATCAGTATCGCTATTTCTGGCCGCAAACCGAACCTGAAATTATTGAGGGAGTATGA

Upstream 100 bases:

>100_bases
TGCGGCTTAGCCCGGTGGCGCAGGCTTACCGGGCCTACGGGCGCGTGAACCGTAGGCCGGATAAGCGTAGCGCCATCAGG
CGGCGTTTATGGAGTTATCT

Downstream 100 bases:

>100_bases
AATGCTAAAAACCATTTCACCGTTAATTTCCCCGACACTGCTCAAAGTGCTGGCCGAGATGGGCCACGGGGACGAAATCA
TTTTTTCTGACGCTCACTTT

Product: L-fuculokinase

Products: NA

Alternate protein names: L-fuculose kinase

Number of amino acids: Translated: 472; Mature: 472

Protein sequence:

>472_residues
MKQDVILVLDCGATNVRAIAVDRQGKIVARASTANASDIAAENSAWHQWSLDAILQRFADCCRSLSSALSECVVRGITVT
TFGVDGALVDAQGKLLYPVISWKCPRTAAVMETIERFISPRQLQTLSGVGAFSFNTLYKLVWLKENHPRLLEQAHCWLFI
SSLINHRLTGEFTTDITMAGTSQLLDIHQRDFSPEILQATGLARRLFPRIVEAGAPIGTLQTDAARLLGLPAGVPVISAE
HDTQFALFGAGAQQGEPVLSSGTWEILMVRSGQVDTSLLSQYPGSTCELDSQSGLYNPGMQWLASGVLEWVRKLLWTPET
PWQTLIDEARAIPAGAEGVRMQCDLLACQNAGWQGVTLNTTRGHFYRAALEGLTAQLQRNLRTLEKIGHFNATELLLVGG
GSRNALWNQIKANQLDIPIKVLDDAETTVAGAAMFGWYGVGEFSSPEQARAQVNYQYRYFWPQTEPEIIEGV

Sequences:

>Translated_472_residues
MKQDVILVLDCGATNVRAIAVDRQGKIVARASTANASDIAAENSAWHQWSLDAILQRFADCCRSLSSALSECVVRGITVT
TFGVDGALVDAQGKLLYPVISWKCPRTAAVMETIERFISPRQLQTLSGVGAFSFNTLYKLVWLKENHPRLLEQAHCWLFI
SSLINHRLTGEFTTDITMAGTSQLLDIHQRDFSPEILQATGLARRLFPRIVEAGAPIGTLQTDAARLLGLPAGVPVISAE
HDTQFALFGAGAQQGEPVLSSGTWEILMVRSGQVDTSLLSQYPGSTCELDSQSGLYNPGMQWLASGVLEWVRKLLWTPET
PWQTLIDEARAIPAGAEGVRMQCDLLACQNAGWQGVTLNTTRGHFYRAALEGLTAQLQRNLRTLEKIGHFNATELLLVGG
GSRNALWNQIKANQLDIPIKVLDDAETTVAGAAMFGWYGVGEFSSPEQARAQVNYQYRYFWPQTEPEIIEGV
>Mature_472_residues
MKQDVILVLDCGATNVRAIAVDRQGKIVARASTANASDIAAENSAWHQWSLDAILQRFADCCRSLSSALSECVVRGITVT
TFGVDGALVDAQGKLLYPVISWKCPRTAAVMETIERFISPRQLQTLSGVGAFSFNTLYKLVWLKENHPRLLEQAHCWLFI
SSLINHRLTGEFTTDITMAGTSQLLDIHQRDFSPEILQATGLARRLFPRIVEAGAPIGTLQTDAARLLGLPAGVPVISAE
HDTQFALFGAGAQQGEPVLSSGTWEILMVRSGQVDTSLLSQYPGSTCELDSQSGLYNPGMQWLASGVLEWVRKLLWTPET
PWQTLIDEARAIPAGAEGVRMQCDLLACQNAGWQGVTLNTTRGHFYRAALEGLTAQLQRNLRTLEKIGHFNATELLLVGG
GSRNALWNQIKANQLDIPIKVLDDAETTVAGAAMFGWYGVGEFSSPEQARAQVNYQYRYFWPQTEPEIIEGV

Specific function: Fucose metabolism; second step. [C]

COG id: COG1070

COG function: function code G; Sugar (pentulose and hexulose) kinases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FGGY kinase family

Homologues:

Organism=Escherichia coli, GI1789168, Length=472, Percent_Identity=84.5338983050847, Blast_Score=842, Evalue=0.0,
Organism=Escherichia coli, GI1787789, Length=469, Percent_Identity=23.454157782516, Blast_Score=103, Evalue=2e-23,
Organism=Escherichia coli, GI1789987, Length=424, Percent_Identity=25.9433962264151, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1790338, Length=420, Percent_Identity=24.5238095238095, Blast_Score=86, Evalue=5e-18,
Organism=Escherichia coli, GI1790005, Length=489, Percent_Identity=23.5173824130879, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1789138, Length=318, Percent_Identity=24.8427672955975, Blast_Score=67, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): FUCK_SALTI (Q8Z428)

Other databases:

- EMBL:   AL627277
- EMBL:   AE014613
- RefSeq:   NP_457372.1
- RefSeq:   NP_806581.1
- ProteinModelPortal:   Q8Z428
- GeneID:   1068698
- GeneID:   1249413
- GenomeReviews:   AE014613_GR
- GenomeReviews:   AL513382_GR
- KEGG:   stt:t2885
- KEGG:   sty:STY3117
- HOGENOM:   HBG296691
- OMA:   NQLALPI
- ProtClustDB:   PRK10331
- BioCyc:   SENT209261:T2885-MONOMER
- BioCyc:   SENT220341:STY3117-MONOMER
- BRENDA:   2.7.1.51
- InterPro:   IPR000577
- InterPro:   IPR018485
- InterPro:   IPR018483
- InterPro:   IPR018484
- InterPro:   IPR013450
- PANTHER:   PTHR10196
- TIGRFAMs:   TIGR02628

Pfam domain/function: PF02782 FGGY_C; PF00370 FGGY_N

EC number: =2.7.1.51

Molecular weight: Translated: 51747; Mature: 51747

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: PS00933 FGGY_KINASES_1; PS00445 FGGY_KINASES_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKQDVILVLDCGATNVRAIAVDRQGKIVARASTANASDIAAENSAWHQWSLDAILQRFAD
CCCCEEEEEECCCCCEEEEEEECCCCEEEEECCCCCHHHCCCCCCCCEECHHHHHHHHHH
CCRSLSSALSECVVRGITVTTFGVDGALVDAQGKLLYPVISWKCPRTAAVMETIERFISP
HHHHHHHHHHHHHHCCCEEEEECCCCEEECCCCCEEEEEECCCCCCHHHHHHHHHHHCCC
RQLQTLSGVGAFSFNTLYKLVWLKENHPRLLEQAHCWLFISSLINHRLTGEFTTDITMAG
HHHHHHHCCCCHHHHHEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCEECEEEECC
TSQLLDIHQRDFSPEILQATGLARRLFPRIVEAGAPIGTLQTDAARLLGLPAGVPVISAE
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCEEECC
HDTQFALFGAGAQQGEPVLSSGTWEILMVRSGQVDTSLLSQYPGSTCELDSQSGLYNPGM
CCCEEEEEECCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHCCCCCEECCCCCCCCCCHH
QWLASGVLEWVRKLLWTPETPWQTLIDEARAIPAGAEGVRMQCDLLACQNAGWQGVTLNT
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCCEEEEC
TRGHFYRAALEGLTAQLQRNLRTLEKIGHFNATELLLVGGGSRNALWNQIKANQLDIPIK
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHCCCCCCCCEE
VLDDAETTVAGAAMFGWYGVGEFSSPEQARAQVNYQYRYFWPQTEPEIIEGV
EECCCCHHHHHHHHHHHCCCCCCCCCHHHHHEEEEEEEEECCCCCCHHHCCC
>Mature Secondary Structure
MKQDVILVLDCGATNVRAIAVDRQGKIVARASTANASDIAAENSAWHQWSLDAILQRFAD
CCCCEEEEEECCCCCEEEEEEECCCCEEEEECCCCCHHHCCCCCCCCEECHHHHHHHHHH
CCRSLSSALSECVVRGITVTTFGVDGALVDAQGKLLYPVISWKCPRTAAVMETIERFISP
HHHHHHHHHHHHHHCCCEEEEECCCCEEECCCCCEEEEEECCCCCCHHHHHHHHHHHCCC
RQLQTLSGVGAFSFNTLYKLVWLKENHPRLLEQAHCWLFISSLINHRLTGEFTTDITMAG
HHHHHHHCCCCHHHHHEEEEEEEECCCHHHHHHHHHHHHHHHHHCCCCCCCEECEEEECC
TSQLLDIHQRDFSPEILQATGLARRLFPRIVEAGAPIGTLQTDAARLLGLPAGVPVISAE
HHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHCCCCCCCEEECC
HDTQFALFGAGAQQGEPVLSSGTWEILMVRSGQVDTSLLSQYPGSTCELDSQSGLYNPGM
CCCEEEEEECCCCCCCCCCCCCCEEEEEEECCCCCHHHHHHCCCCCEECCCCCCCCCCHH
QWLASGVLEWVRKLLWTPETPWQTLIDEARAIPAGAEGVRMQCDLLACQNAGWQGVTLNT
HHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCEEEEEEEEECCCCCCCEEEEC
TRGHFYRAALEGLTAQLQRNLRTLEKIGHFNATELLLVGGGSRNALWNQIKANQLDIPIK
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCHHHHHHCCCCCCCCEE
VLDDAETTVAGAAMFGWYGVGEFSSPEQARAQVNYQYRYFWPQTEPEIIEGV
EECCCCHHHHHHHHHHHCCCCCCCCCHHHHHEEEEEEEEECCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504