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The map label for this gene is spaP

Identifier: 29143151

GI number: 29143151

Start: 2871528

End: 2872202

Strand: Reverse

Name: spaP

Synonym: t2792

Alternate gene names: 29143151

Gene position: 2872202-2871528 (Counterclockwise)

Preceding gene: 29143152

Following gene: 29143150

Centisome position: 59.94

GC content: 41.48

Gene sequence:

>675_bases
ATGGGGAATGATATCTCATTAATTGCCTTACTGGCATTTTCCACCCTGTTGCCATTTATTATTGCGTCAGGAACCTGTTT
CGTTAAATTTTCTATTGTATTTGTCATGGTGCGTAACGCCCTGGGATTGCAGCAGATACCTTCAAATATGACGCTTAACA
GCGTCGCATTGCTGCTTTCTATGTTTGTTATGTGGCCAATAATGCATGATGCCTACGTCTATTTTGAGGACGAAGATGTC
ACCTTTAATGATATTTCGTCATTAAGTAAACACGTTGATGAAGGTCTGGATGGTTATCGCGATTATCTGATCAAATATTC
AGATCGCGAGTTAGTTCAGTTTTTTGAAAACGCGCAACTGAAGCGTCAGTATGGAGAAGAGACCGAGACGGTAAAGCGTG
ACAAAGATGAAATTGAAAAACCATCAATATTTGCGTTATTACCTGCTTATGCGCTGAGCGAAATAAAAAGCGCGTTTAAA
ATTGGTTTTTATCTCTATTTGCCCTTTGTTGTCGTCGACCTGGTGGTATCCAGCGTGCTACTGGCGCTGGGGATGATGAT
GATGAGTCCGGTGACGATATCTACACCTATTAAGCTGGTGCTTTTTGTCGCGCTTGATGGCTGGACCTTACTGTCTAAGG
GATTGATATTACAGTATATGGACATTGCAACATGA

Upstream 100 bases:

>100_bases
GAAATTATGGCGAATGGTGTTTTGCTTGGTAATGGCGAACTGGTACAGATGAATGACACCTTAGGCGTTGAGATCCATGA
ATGGCTGAGCGAGTCTGGTA

Downstream 100 bases:

>100_bases
CATCATTACGAGACGGGATAGTTAAATGGATGATTTAGTGTTTGCAGGTAATAAGGCGCTCTATCTTGTTTTGATCCTGT
CAGGGTGGCCGACGATTGTC

Product: surface presentation of antigens protein SpaP

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 224; Mature: 223

Protein sequence:

>224_residues
MGNDISLIALLAFSTLLPFIIASGTCFVKFSIVFVMVRNALGLQQIPSNMTLNSVALLLSMFVMWPIMHDAYVYFEDEDV
TFNDISSLSKHVDEGLDGYRDYLIKYSDRELVQFFENAQLKRQYGEETETVKRDKDEIEKPSIFALLPAYALSEIKSAFK
IGFYLYLPFVVVDLVVSSVLLALGMMMMSPVTISTPIKLVLFVALDGWTLLSKGLILQYMDIAT

Sequences:

>Translated_224_residues
MGNDISLIALLAFSTLLPFIIASGTCFVKFSIVFVMVRNALGLQQIPSNMTLNSVALLLSMFVMWPIMHDAYVYFEDEDV
TFNDISSLSKHVDEGLDGYRDYLIKYSDRELVQFFENAQLKRQYGEETETVKRDKDEIEKPSIFALLPAYALSEIKSAFK
IGFYLYLPFVVVDLVVSSVLLALGMMMMSPVTISTPIKLVLFVALDGWTLLSKGLILQYMDIAT
>Mature_223_residues
GNDISLIALLAFSTLLPFIIASGTCFVKFSIVFVMVRNALGLQQIPSNMTLNSVALLLSMFVMWPIMHDAYVYFEDEDVT
FNDISSLSKHVDEGLDGYRDYLIKYSDRELVQFFENAQLKRQYGEETETVKRDKDEIEKPSIFALLPAYALSEIKSAFKI
GFYLYLPFVVVDLVVSSVLLALGMMMMSPVTISTPIKLVLFVALDGWTLLSKGLILQYMDIAT

Specific function: Involved in a secretory pathway responsible for the surface presentation of determinants needed for the entry of Salmonella species into mammalian cells

COG id: COG4790

COG function: function code U; Type III secretory pathway, component EscR

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fliP/mopC/spaP family

Homologues:

Organism=Escherichia coli, GI1788259, Length=206, Percent_Identity=37.378640776699, Blast_Score=132, Evalue=1e-32,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): SPAP_SALTI (Q56023)

Other databases:

- EMBL:   U29363
- EMBL:   AL627276
- EMBL:   AE014613
- RefSeq:   NP_457284.1
- RefSeq:   NP_806493.1
- GeneID:   1068867
- GeneID:   1249319
- GenomeReviews:   AE014613_GR
- GenomeReviews:   AL513382_GR
- KEGG:   stt:t2792
- KEGG:   sty:STY3013
- HOGENOM:   HBG414116
- OMA:   IASGTYF
- ProtClustDB:   PRK12796
- BioCyc:   SENT209261:T2792-MONOMER
- BioCyc:   SENT220341:STY3013-MONOMER
- GO:   GO:0009405
- InterPro:   IPR005838
- InterPro:   IPR005773
- PRINTS:   PR01302
- TIGRFAMs:   TIGR01102

Pfam domain/function: PF00813 FliP

EC number: NA

Molecular weight: Translated: 25262; Mature: 25131

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: PS01060 FLIP_1; PS01061 FLIP_2

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x108bf114)-; HASH(0x10880994)-; HASH(0x108e7240)-; HASH(0x10977ce8)-;

Cys/Met content:

0.4 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGNDISLIALLAFSTLLPFIIASGTCFVKFSIVFVMVRNALGLQQIPSNMTLNSVALLLS
CCCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHCCCCCCHHHHHHHHH
MFVMWPIMHDAYVYFEDEDVTFNDISSLSKHVDEGLDGYRDYLIKYSDRELVQFFENAQL
HHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
KRQYGEETETVKRDKDEIEKPSIFALLPAYALSEIKSAFKIGFYLYLPFVVVDLVVSSVL
HHHHCCHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LALGMMMMSPVTISTPIKLVLFVALDGWTLLSKGLILQYMDIAT
HHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCH
>Mature Secondary Structure 
GNDISLIALLAFSTLLPFIIASGTCFVKFSIVFVMVRNALGLQQIPSNMTLNSVALLLS
CCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCHHHCCCCCCHHHHHHHHH
MFVMWPIMHDAYVYFEDEDVTFNDISSLSKHVDEGLDGYRDYLIKYSDRELVQFFENAQL
HHHHHHHHHCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
KRQYGEETETVKRDKDEIEKPSIFALLPAYALSEIKSAFKIGFYLYLPFVVVDLVVSSVL
HHHHCCHHHHHHCCHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LALGMMMMSPVTISTPIKLVLFVALDGWTLLSKGLILQYMDIAT
HHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7638176; 11677608; 12644504