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The map label for this gene is sitC [H]

Identifier: 29143124

GI number: 29143124

Start: 2846851

End: 2847711

Strand: Direct

Name: sitC [H]

Synonym: t2765

Alternate gene names: 29143124

Gene position: 2846851-2847711 (Clockwise)

Preceding gene: 29143123

Following gene: 29143125

Centisome position: 59.41

GC content: 54.82

Gene sequence:

>861_bases
ATGAACTGGCTTGTTGAGCCGTTTGGCTACCAGTATATGCTCAACGCGATGTGGGTCTCCGCGATGGTGGGCGGTCTTTG
CGCGTTTCTCTCCTGCTATTTGATGCTCAAAGGCTGGTCGCTCATTGGCGATGCGCTATCTCACTCTATTGTGCCTGGCG
TCGCTGGCGCCTGGATGTTAGGGCTGCCCTTCTCGCTCGGCGCGTTTCTTTCCGGCGGACTGGCGGCAGGCAGTATGCTC
TTTCTTAACCAACGCTCACGCCTGAAAGAAGACGCGATTATCGGGCTTATCTTCTCCTCTTTTTTTGGCGTCGGCCTTTT
TATGGTGTCGCTCAATCCGATGTCGGTGAATATCCAGACGATTATTCTCGGCAACGTGCTGGCGATCGCGCCAGCGGATA
TTACGCAACTGGCGATTATCGGCGCAGTCTCGCTGACGATTCTGCTGTTAAAGTGGAAAGATCTGATGGTCGTCTTTTTC
GATGAGACCCATGCGCGTTCTATCGGGCTTAATCCGGGTCGACTAAAATTGTTGTTTTTCACTCTATTGTCCGTCTCTAC
CGTGGCGGCCCTGCAAACCGTTGGGGCGTTCCTGGTGATCTGTCTCGTCGTCACGCCGGGCGCGACGGCCTGGTTACTCA
CCGACCGTTTTCCACGTCTGCTCATGATTGCCGTCGTGATTGGCAGCCTGACCAGTTTTCTGGGCGCATGGCTTAGCTAC
TGGCTGGATGGCGCCACTGGCGGAATTATTGTCGTCATGCAAACCTTACTGTTCATCACGGCCTTTATTTTCGCCCCGAA
ACACGGTCTGTTAGCCAACCGTCGACGCGCCCGCCTGCAGAAGGAGCCGACATGTTCTTAG

Upstream 100 bases:

>100_bases
TTCTACGTCATATCGCGCTAAGCGGAGGTGAAGAGCACATCATCACCGATGACGAGCGCCCCTTTATTTCCCGACGCGTG
GCCAGCGGAGGAAAATCGTC

Downstream 100 bases:

>100_bases
CAACGTTACTGGAACCCTTTCAGTTTGATTTTATGGTGAACGCCCTTATGGTTTCGGTCATTGTGGCGATTCCCTGCGCC
TTGCTGTCCGTGTTTTTAGT

Product: iron transporter inner membrane protein

Products: Zn (II) [Cytoplasm]; ADP; phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 286; Mature: 286

Protein sequence:

>286_residues
MNWLVEPFGYQYMLNAMWVSAMVGGLCAFLSCYLMLKGWSLIGDALSHSIVPGVAGAWMLGLPFSLGAFLSGGLAAGSML
FLNQRSRLKEDAIIGLIFSSFFGVGLFMVSLNPMSVNIQTIILGNVLAIAPADITQLAIIGAVSLTILLLKWKDLMVVFF
DETHARSIGLNPGRLKLLFFTLLSVSTVAALQTVGAFLVICLVVTPGATAWLLTDRFPRLLMIAVVIGSLTSFLGAWLSY
WLDGATGGIIVVMQTLLFITAFIFAPKHGLLANRRRARLQKEPTCS

Sequences:

>Translated_286_residues
MNWLVEPFGYQYMLNAMWVSAMVGGLCAFLSCYLMLKGWSLIGDALSHSIVPGVAGAWMLGLPFSLGAFLSGGLAAGSML
FLNQRSRLKEDAIIGLIFSSFFGVGLFMVSLNPMSVNIQTIILGNVLAIAPADITQLAIIGAVSLTILLLKWKDLMVVFF
DETHARSIGLNPGRLKLLFFTLLSVSTVAALQTVGAFLVICLVVTPGATAWLLTDRFPRLLMIAVVIGSLTSFLGAWLSY
WLDGATGGIIVVMQTLLFITAFIFAPKHGLLANRRRARLQKEPTCS
>Mature_286_residues
MNWLVEPFGYQYMLNAMWVSAMVGGLCAFLSCYLMLKGWSLIGDALSHSIVPGVAGAWMLGLPFSLGAFLSGGLAAGSML
FLNQRSRLKEDAIIGLIFSSFFGVGLFMVSLNPMSVNIQTIILGNVLAIAPADITQLAIIGAVSLTILLLKWKDLMVVFF
DETHARSIGLNPGRLKLLFFTLLSVSTVAALQTVGAFLVICLVVTPGATAWLLTDRFPRLLMIAVVIGSLTSFLGAWLSY
WLDGATGGIIVVMQTLLFITAFIFAPKHGLLANRRRARLQKEPTCS

Specific function: Part of an ATP-driven transport system yfeABC for chelated iron [H]

COG id: COG1108

COG function: function code P; ABC-type Mn2+/Zn2+ transport systems, permease components

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ABC-3 integral membrane protein family [H]

Homologues:

Organism=Escherichia coli, GI1788166, Length=231, Percent_Identity=27.2727272727273, Blast_Score=79, Evalue=4e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001626 [H]

Pfam domain/function: PF00950 ABC-3 [H]

EC number: NA

Molecular weight: Translated: 30896; Mature: 30896

Theoretical pI: Translated: 9.60; Mature: 9.60

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNWLVEPFGYQYMLNAMWVSAMVGGLCAFLSCYLMLKGWSLIGDALSHSIVPGVAGAWML
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
GLPFSLGAFLSGGLAAGSMLFLNQRSRLKEDAIIGLIFSSFFGVGLFMVSLNPMSVNIQT
CCHHHHHHHHHCCHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEEE
IILGNVLAIAPADITQLAIIGAVSLTILLLKWKDLMVVFFDETHARSIGLNPGRLKLLFF
EEECCCCEECCCHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCHHHHHHH
TLLSVSTVAALQTVGAFLVICLVVTPGATAWLLTDRFPRLLMIAVVIGSLTSFLGAWLSY
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WLDGATGGIIVVMQTLLFITAFIFAPKHGLLANRRRARLQKEPTCS
HHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MNWLVEPFGYQYMLNAMWVSAMVGGLCAFLSCYLMLKGWSLIGDALSHSIVPGVAGAWML
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
GLPFSLGAFLSGGLAAGSMLFLNQRSRLKEDAIIGLIFSSFFGVGLFMVSLNPMSVNIQT
CCHHHHHHHHHCCHHHHHHHEEHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCEEEEEE
IILGNVLAIAPADITQLAIIGAVSLTILLLKWKDLMVVFFDETHARSIGLNPGRLKLLFF
EEECCCCEECCCHHHHHHHHHHHHHHHHHHHHCCEEEEEECCCCCCCCCCCCCHHHHHHH
TLLSVSTVAALQTVGAFLVICLVVTPGATAWLLTDRFPRLLMIAVVIGSLTSFLGAWLSY
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WLDGATGGIIVVMQTLLFITAFIFAPKHGLLANRRRARLQKEPTCS
HHCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Zn (II) [Periplasm]; H2O; ATP [C]

Specific reaction: Zn (II) [Periplasm] + H2O + ATP = Zn (II) [Cytoplasm] + ADP + phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9495751; 11586360; 12142430 [H]