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The map label for this gene is intA [H]

Identifier: 29143016

GI number: 29143016

Start: 2735202

End: 2736233

Strand: Direct

Name: intA [H]

Synonym: t2647

Alternate gene names: 29143016

Gene position: 2735202-2736233 (Clockwise)

Preceding gene: 29143015

Following gene: 29143020

Centisome position: 57.08

GC content: 44.19

Gene sequence:

>1032_bases
ATGATGGGGCTAGGTACCTTCCCAGCTCTTTCACTTGCTGACGCCCGACGGTTAAGAGCGGATTACCTTTCCTTGTTAGC
CAACGGAATTGACCCGCAAATTCAAGCTGAAATTGCAGAGGAACAGCAGCAAATCGCACAGGACAGTATTTTTACAACGG
TCGCCGCTAACTGGTTCCAGCTTAAAAGCAAAAGCGTAACCCCTGATTACGCAAGAGACATTTGGCGCTCATTGGAGAAA
GATGTATTCCCTGCCGTTGGTGAACTCCCAGTTCAGCAAATCAAAGCCCGAACGTTGGTTGAAGCGCTTGAGCCAGTCAA
AGCTCGTGGGGCGCTAGAGACTGTACGTCGGCTAGTGCAACGCATTAACGAGATAATGATCTTTGCCGTAAATACAGGGC
TGATCGATGCCAATCCAGCTTCCGGGGTTGGAATGGCCTTTGAGAAGCCAAAAAAGCAAAACATGCCAACACTACGACCA
GAAGAACTACCAAATCTAATGCGTTCTTTAGCCATGTCTAATTTATCTGTATCGACTCGCTGCCTTATCGAATGGCAGCT
TCTAACACTTGTACGCCCTTCTGAAGCCTCTGGTACTCAATGGGCAGAGATCGATCTTGAGAATAAACTCTGGACGATCC
CTGCAGGACGAATGAAAGCCAAGCGAGAACATATTGTTCCTCTGTCGGTTCGAGCATTAGATATTTTAGAGATAATGAAG
CCTATTAGTGCACATCGTGAATATGTTTTCCCAAGTAGAAATAATCCTAAGCAACCAATGAATAGTCAGACAGCTAATGC
TGCATTAAAAAGAATTGGTTATGGAGGAAAGCTTGTTGCACATGGTTTGCGTTCTATAGCCAGTACAGCTATGAATGAGG
AAGGTTTTAATCCCGATGTTATTGAAGCAGCATTAGCGCATAGCGATAAAAATGAAGTCCGTAAAGCATATAATCGTTCG
ACTTACCTTTATCAACGAATTGATTTAATGAATTGGTGGGCTAACTTCGTGTTTAAAAAAACACACGAATAG

Upstream 100 bases:

>100_bases
AACGTTGCATGATGGCGATGGTCTTTTTCTACTCGTTAAAACGAACGGTAAGAAGTTATGGCGTTTCCGTTATCAACGTC
CGGCAACAAAGCAGCGGACA

Downstream 100 bases:

>100_bases
CCCACATAAAATAAGAGGCTGCTCAATGCAGCCATTATTTCAATGAATTAATATACGTATTTAATCCTGTTGATTTTATA
ACTCCCATCACTTCTGGTGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MMGLGTFPALSLADARRLRADYLSLLANGIDPQIQAEIAEEQQQIAQDSIFTTVAANWFQLKSKSVTPDYARDIWRSLEK
DVFPAVGELPVQQIKARTLVEALEPVKARGALETVRRLVQRINEIMIFAVNTGLIDANPASGVGMAFEKPKKQNMPTLRP
EELPNLMRSLAMSNLSVSTRCLIEWQLLTLVRPSEASGTQWAEIDLENKLWTIPAGRMKAKREHIVPLSVRALDILEIMK
PISAHREYVFPSRNNPKQPMNSQTANAALKRIGYGGKLVAHGLRSIASTAMNEEGFNPDVIEAALAHSDKNEVRKAYNRS
TYLYQRIDLMNWWANFVFKKTHE

Sequences:

>Translated_343_residues
MMGLGTFPALSLADARRLRADYLSLLANGIDPQIQAEIAEEQQQIAQDSIFTTVAANWFQLKSKSVTPDYARDIWRSLEK
DVFPAVGELPVQQIKARTLVEALEPVKARGALETVRRLVQRINEIMIFAVNTGLIDANPASGVGMAFEKPKKQNMPTLRP
EELPNLMRSLAMSNLSVSTRCLIEWQLLTLVRPSEASGTQWAEIDLENKLWTIPAGRMKAKREHIVPLSVRALDILEIMK
PISAHREYVFPSRNNPKQPMNSQTANAALKRIGYGGKLVAHGLRSIASTAMNEEGFNPDVIEAALAHSDKNEVRKAYNRS
TYLYQRIDLMNWWANFVFKKTHE
>Mature_343_residues
MMGLGTFPALSLADARRLRADYLSLLANGIDPQIQAEIAEEQQQIAQDSIFTTVAANWFQLKSKSVTPDYARDIWRSLEK
DVFPAVGELPVQQIKARTLVEALEPVKARGALETVRRLVQRINEIMIFAVNTGLIDANPASGVGMAFEKPKKQNMPTLRP
EELPNLMRSLAMSNLSVSTRCLIEWQLLTLVRPSEASGTQWAEIDLENKLWTIPAGRMKAKREHIVPLSVRALDILEIMK
PISAHREYVFPSRNNPKQPMNSQTANAALKRIGYGGKLVAHGLRSIASTAMNEEGFNPDVIEAALAHSDKNEVRKAYNRS
TYLYQRIDLMNWWANFVFKKTHE

Specific function: Integrase is necessary for integration of the phage into the host genome by site-specific recombination. In conjunction with excisionase, integrase is also necessary for excision of the prophage from the host genome [H]

COG id: COG0582

COG function: function code L; Integrase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family [H]

Homologues:

Organism=Escherichia coli, GI1788974, Length=335, Percent_Identity=61.4925373134328, Blast_Score=434, Evalue=1e-123,
Organism=Escherichia coli, GI145693166, Length=338, Percent_Identity=34.9112426035503, Blast_Score=186, Evalue=1e-48,
Organism=Escherichia coli, GI1788690, Length=345, Percent_Identity=30.1449275362319, Blast_Score=183, Evalue=1e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR023109 [H]

Pfam domain/function: PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 38577; Mature: 38577

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMGLGTFPALSLADARRLRADYLSLLANGIDPQIQAEIAEEQQQIAQDSIFTTVAANWFQ
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKSKSVTPDYARDIWRSLEKDVFPAVGELPVQQIKARTLVEALEPVKARGALETVRRLVQ
HCCCCCCHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
RINEIMIFAVNTGLIDANPASGVGMAFEKPKKQNMPTLRPEELPNLMRSLAMSNLSVSTR
HHHHEEEEEEECCEEECCCCCCCCCCCCCCHHCCCCCCCHHHHHHHHHHHHHHCCCCCHH
CLIEWQLLTLVRPSEASGTQWAEIDLENKLWTIPAGRMKAKREHIVPLSVRALDILEIMK
HHEEEEHHHEECCCCCCCCEEEEEEECCCEEECCCHHHHHHHHCCCCHHHHHHHHHHHHH
PISAHREYVFPSRNNPKQPMNSQTANAALKRIGYGGKLVAHGLRSIASTAMNEEGFNPDV
HHHHHHCEECCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHH
IEAALAHSDKNEVRKAYNRSTYLYQRIDLMNWWANFVFKKTHE
HHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMGLGTFPALSLADARRLRADYLSLLANGIDPQIQAEIAEEQQQIAQDSIFTTVAANWFQ
CCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LKSKSVTPDYARDIWRSLEKDVFPAVGELPVQQIKARTLVEALEPVKARGALETVRRLVQ
HCCCCCCHHHHHHHHHHHHHHHCCHHCCCCHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
RINEIMIFAVNTGLIDANPASGVGMAFEKPKKQNMPTLRPEELPNLMRSLAMSNLSVSTR
HHHHEEEEEEECCEEECCCCCCCCCCCCCCHHCCCCCCCHHHHHHHHHHHHHHCCCCCHH
CLIEWQLLTLVRPSEASGTQWAEIDLENKLWTIPAGRMKAKREHIVPLSVRALDILEIMK
HHEEEEHHHEECCCCCCCCEEEEEEECCCEEECCCHHHHHHHHCCCCHHHHHHHHHHHHH
PISAHREYVFPSRNNPKQPMNSQTANAALKRIGYGGKLVAHGLRSIASTAMNEEGFNPDV
HHHHHHCEECCCCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCHHH
IEAALAHSDKNEVRKAYNRSTYLYQRIDLMNWWANFVFKKTHE
HHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7511583; 9278503; 9205837; 7524073 [H]