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The map label for this gene is tcfB [H]

Identifier: 29142931

GI number: 29142931

Start: 2628013

End: 2628588

Strand: Reverse

Name: tcfB [H]

Synonym: t2549

Alternate gene names: 29142931

Gene position: 2628588-2628013 (Counterclockwise)

Preceding gene: 29142932

Following gene: 29142930

Centisome position: 54.85

GC content: 47.05

Gene sequence:

>576_bases
ATGTATACCGAGTGTACATATATCACTGTAATAAACAACAAAGCAAGGTTATTTTTTATGAACATGAAAACATCTTTTAT
TGCCGCAGCTGTGGCATTGGCCACCGTTTATTCTTTTTCTGTTTCTGCGGTTCAGAAGGATATTACCGTCACTGCCAATA
TTGACAGTACACTTGAACTGCTGCAGGCCGATGGTTCATCCCTCCCGTCGACTATGAAGCTGGATTTCATGCCGGGTAAG
GGCCTGGTCCATAAATCACTCCAGACCCGCCTTTACAGCAACGATCAGACCAAGTCGGTTAATGTAAAACTGTTGAATGC
TCCACAACTTATCAACGTCCTGGATCCCACCAAAACCATTGATATGGAAGTGACTCTGGGAGGACGGTCACTGACCACCA
CCAATTCTGTACTGGAAGCTAAAACCCTGTTCCCGGACGGAAAAACTGGCGATGCTTCAGCTCTGCTGAACCTGGATATT
GGTCAGAAGGCTGGAGCAGCCTTACAAAACCTGCCTGCCGGTGAATACAGCGGATTGGTCAGTCTGGTGATTTCACAGGC
TGTCACTGCCGGCTAA

Upstream 100 bases:

>100_bases
GTGCAAATTCACCGGTAATCTCTGCTGATTTAACAGCAGCCGGAAAGTAAAAACACACGGAGCGTACGCTATACCCTACA
TTTATTCTCAGGGGGAGCGG

Downstream 100 bases:

>100_bases
TAACTGGTTATTAGCTCTTCATCTGATCCGGTTTTGGGGGGGCACCGTTCGTACCTGAACCGGATCCGGTATTGATCTTA
TTATTCATTGCAATTCAGGT

Product: fimbrial subunit

Products: NA

Alternate protein names: CFA/I antigen; CFA/I pilin; Colonization factor antigen I subunit B [H]

Number of amino acids: Translated: 191; Mature: 191

Protein sequence:

>191_residues
MYTECTYITVINNKARLFFMNMKTSFIAAAVALATVYSFSVSAVQKDITVTANIDSTLELLQADGSSLPSTMKLDFMPGK
GLVHKSLQTRLYSNDQTKSVNVKLLNAPQLINVLDPTKTIDMEVTLGGRSLTTTNSVLEAKTLFPDGKTGDASALLNLDI
GQKAGAALQNLPAGEYSGLVSLVISQAVTAG

Sequences:

>Translated_191_residues
MYTECTYITVINNKARLFFMNMKTSFIAAAVALATVYSFSVSAVQKDITVTANIDSTLELLQADGSSLPSTMKLDFMPGK
GLVHKSLQTRLYSNDQTKSVNVKLLNAPQLINVLDPTKTIDMEVTLGGRSLTTTNSVLEAKTLFPDGKTGDASALLNLDI
GQKAGAALQNLPAGEYSGLVSLVISQAVTAG
>Mature_191_residues
MYTECTYITVINNKARLFFMNMKTSFIAAAVALATVYSFSVSAVQKDITVTANIDSTLELLQADGSSLPSTMKLDFMPGK
GLVHKSLQTRLYSNDQTKSVNVKLLNAPQLINVLDPTKTIDMEVTLGGRSLTTTNSVLEAKTLFPDGKTGDASALLNLDI
GQKAGAALQNLPAGEYSGLVSLVISQAVTAG

Specific function: Fimbriae (also called pili), polar filaments radiating from the surface of the bacterium to a length of 0.5-1.5 micrometers and numbering 100-300 per cell, enable bacteria to colonize the epithelium of specific host organs [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Fimbrium [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fimbrial CS1 protein family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007540 [H]

Pfam domain/function: PF04449 Fimbrial_CS1 [H]

EC number: NA

Molecular weight: Translated: 20283; Mature: 20283

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYTECTYITVINNKARLFFMNMKTSFIAAAVALATVYSFSVSAVQKDITVTANIDSTLEL
CCCCEEEEEEECCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHH
LQADGSSLPSTMKLDFMPGKGLVHKSLQTRLYSNDQTKSVNVKLLNAPQLINVLDPTKTI
HHCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEECCCCEEE
DMEVTLGGRSLTTTNSVLEAKTLFPDGKTGDASALLNLDIGQKAGAALQNLPAGEYSGLV
EEEEEECCCEEECCCHHHHHEEECCCCCCCCCEEEEEECCCCCCCHHHHCCCCCHHHHHH
SLVISQAVTAG
HHHHHHHHCCC
>Mature Secondary Structure
MYTECTYITVINNKARLFFMNMKTSFIAAAVALATVYSFSVSAVQKDITVTANIDSTLEL
CCCCEEEEEEECCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHCCEEEEECCHHHHHH
LQADGSSLPSTMKLDFMPGKGLVHKSLQTRLYSNDQTKSVNVKLLNAPQLINVLDPTKTI
HHCCCCCCCCEEEEEECCCCCHHHHHHHHHHCCCCCCCEEEEEEECCCCEEEECCCCEEE
DMEVTLGGRSLTTTNSVLEAKTLFPDGKTGDASALLNLDIGQKAGAALQNLPAGEYSGLV
EEEEEECCCEEECCCHHHHHEEECCCCCCCCCEEEEEECCCCCCCHHHHCCCCCHHHHHH
SLVISQAVTAG
HHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2564374; 2569152; 6124420; 2572583 [H]