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The map label for this gene is foxA [H]

Identifier: 29142886

GI number: 29142886

Start: 2574766

End: 2576856

Strand: Reverse

Name: foxA [H]

Synonym: t2500

Alternate gene names: 29142886

Gene position: 2576856-2574766 (Counterclockwise)

Preceding gene: 29142887

Following gene: 29142884

Centisome position: 53.77

GC content: 52.75

Gene sequence:

>2091_bases
ATGTTTGCGACAACGCGTATGGCGCTATTGATAGGCGGAGCTATCGGCGGCGCGACTTTTCCTCTTTTTGCCCAGGAAAC
CACAAAAAATGATACCGTCATTGTCACCTCGCCCGTTCAGAGTGGCGCGACCAGGCTGGCGACGCCAGATATTGAAACGC
CGCAGTCGGTATCCATTATTACCCGCCAGCAGTTTGAAGAGCAGGGCGCAACCAGCGTGCGTCAGGCGGTCAGCTACACC
CCAGGCGTATACAGTAACCAGATAGGCGCCTCTAACCGCTTTGATTACATCGTATTGCGTGGTTTTTCGGACGGTAGTCT
GGATAACGTCTATCTCGACGGGTTAAAAATGATGGGCGACACCAATTCGCACAGTTCGTTGGTGGTTGACCCCTGGTTTC
TGGAAGATATCGAGGTGGTACGCGGCCCGGCGTCCGTTCTGTATGGACGTTCATCGCCAGGCGGCATTGTCTCGTTGACG
TCGCGAAAACCGGCGTTTGATGCCGGAGGAGAAGTGAAGCTGTTTGCCGGCAATAACAACCAGCGCGGGGCGGCTTTTGA
TGTGACCGGCCCACTGGATGACAATGAACGTGTGGCGGCGCGTCTTAGCGGCATGACACGTTACGCCGATTCGCAGTTTA
CGCCCCTGAAAGAGGAACGTTATGCGCTGATGCCGAGCCTGACCTGGAGAATTACCGATCGGACGCGTCTTGATCTTATG
GCCTATCTGCACCGTGATCCGCAAGGCGGTAGCCACTCCGGACTGCCTTATCAAGGCACGGTTGTACCTTATAACGGCGG
AAAAATTTCTAACACTTTCTTTGAAGGTGAAGATGACTACGACAAATACGATCGCCGTGAAAATATGGTGGGTTATAACA
TTGAGCATCTGTTCGATAACGGCTGGTCGGTACGGCAAAAATTGCGTTATTTGCATACCAAAGTGACGTTGAATCAGGTC
TATGCCGCAGGTTGGTTGAATGAAACGGCGCTGAATCGCGGCTATTCCGGCTCCGGGGAGAAAATGTCGGCTATCGCGCT
GGATAATCAGCTCGACGGCAGCGTGGATACCGGGGCGATTAATCATCGTCTGCTGGTGGGGATCGATTATCAGGATCGCA
GTAATCATACTACTGGCTATTATGGCGCGTTTCCGCCGATTGACGCTTTCAACCCTGTTTATGGCGCTCAGCCGGATTAC
ATTACGTTGTATAGCCGTGAAAAACATAAGCTGCGGCAGACCGGATACTATTTACAGGATCAGATGTCATGGGATCGCTG
GCGCTTTACGTTGGGCGGTCGTTACGATCGGGTCAGCGTGTCTAACATCGACAAACTTCATGATTCACGCAGCGATCTCG
ATAAAAACAACGTCAGCACCCGTGCCGCGTTGCTTTATCTGTTCGACAATGGCGTCGCCCCCTATCTCAGTTATTCTACC
GCGTTTACGTCGACCAGCTTCGCCGACGAAAACGGCAATGTGCTGGAACCGATGAAAGGCAAGCAGTGGGAGGCGGGGGT
AAAATACGAACCGCTGGGGGGGAACAGCCAGTTTAGCGCCGCCGTGTATCGTATTAACCAAACCAATATCGCGACCAAAG
AAGAACCTACCGATCCGTACCGCTCGATTGGTGAAATTGAGTCTAAAGGGGTTGAACTGGAGGCCATTAGCCATTTGTCG
GATAGCGTCCGTTTGCAGGCGGCGTATACCTATACTGATATCCGTTATAAGAAAAGTAGCCCGCAAGAGCAGGGGAAGCG
CGCGGTTTATGCTCCACGGAACCAGGCCAGCGCCTGGCTAAGCTACGATGTGAAAAGCGGTCTGTTAGAGTGGCTGACTT
TGGGCTCCGGCATCCGGTACGTCAACGGCGTGACCAGCGATCGCCTGAATACCCACACGTTGCCGTCCTATACACTGGTC
GACATGGTGGTTGGGTATGATTTATCCAGCATTGGGTTAAATGGCTTGAGCGCCCAGCTCAACGTAAATAATCTGACGGA
CAAACGCTATGTCGCTGCCTGTAATTCGCTCTCTTATTGTTATTTTGGCGCCGAGCGTAGCATTGTAGGCAGCGTGTCAT
GGGCGTTTTGA

Upstream 100 bases:

>100_bases
TTATCATTGCGCATAGGCAATCTGGCGTTACGCATAGTGGTTCGTTATCTCTAAAGGGTAATAATTCTTATTTACAATAA
AGATGCCTTTGGAGATGTTC

Downstream 100 bases:

>100_bases
TAACGCTTATCGTCCGGTAGCAAAGGCTACCGGGCAAACATTAGCGGTGCGTCATGCCTTCATAGAGAAGTCTGAGCGCA
AACATCCCGATAATGGCGCC

Product: ferrioxamine B receptor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 696; Mature: 696

Protein sequence:

>696_residues
MFATTRMALLIGGAIGGATFPLFAQETTKNDTVIVTSPVQSGATRLATPDIETPQSVSIITRQQFEEQGATSVRQAVSYT
PGVYSNQIGASNRFDYIVLRGFSDGSLDNVYLDGLKMMGDTNSHSSLVVDPWFLEDIEVVRGPASVLYGRSSPGGIVSLT
SRKPAFDAGGEVKLFAGNNNQRGAAFDVTGPLDDNERVAARLSGMTRYADSQFTPLKEERYALMPSLTWRITDRTRLDLM
AYLHRDPQGGSHSGLPYQGTVVPYNGGKISNTFFEGEDDYDKYDRRENMVGYNIEHLFDNGWSVRQKLRYLHTKVTLNQV
YAAGWLNETALNRGYSGSGEKMSAIALDNQLDGSVDTGAINHRLLVGIDYQDRSNHTTGYYGAFPPIDAFNPVYGAQPDY
ITLYSREKHKLRQTGYYLQDQMSWDRWRFTLGGRYDRVSVSNIDKLHDSRSDLDKNNVSTRAALLYLFDNGVAPYLSYST
AFTSTSFADENGNVLEPMKGKQWEAGVKYEPLGGNSQFSAAVYRINQTNIATKEEPTDPYRSIGEIESKGVELEAISHLS
DSVRLQAAYTYTDIRYKKSSPQEQGKRAVYAPRNQASAWLSYDVKSGLLEWLTLGSGIRYVNGVTSDRLNTHTLPSYTLV
DMVVGYDLSSIGLNGLSAQLNVNNLTDKRYVAACNSLSYCYFGAERSIVGSVSWAF

Sequences:

>Translated_696_residues
MFATTRMALLIGGAIGGATFPLFAQETTKNDTVIVTSPVQSGATRLATPDIETPQSVSIITRQQFEEQGATSVRQAVSYT
PGVYSNQIGASNRFDYIVLRGFSDGSLDNVYLDGLKMMGDTNSHSSLVVDPWFLEDIEVVRGPASVLYGRSSPGGIVSLT
SRKPAFDAGGEVKLFAGNNNQRGAAFDVTGPLDDNERVAARLSGMTRYADSQFTPLKEERYALMPSLTWRITDRTRLDLM
AYLHRDPQGGSHSGLPYQGTVVPYNGGKISNTFFEGEDDYDKYDRRENMVGYNIEHLFDNGWSVRQKLRYLHTKVTLNQV
YAAGWLNETALNRGYSGSGEKMSAIALDNQLDGSVDTGAINHRLLVGIDYQDRSNHTTGYYGAFPPIDAFNPVYGAQPDY
ITLYSREKHKLRQTGYYLQDQMSWDRWRFTLGGRYDRVSVSNIDKLHDSRSDLDKNNVSTRAALLYLFDNGVAPYLSYST
AFTSTSFADENGNVLEPMKGKQWEAGVKYEPLGGNSQFSAAVYRINQTNIATKEEPTDPYRSIGEIESKGVELEAISHLS
DSVRLQAAYTYTDIRYKKSSPQEQGKRAVYAPRNQASAWLSYDVKSGLLEWLTLGSGIRYVNGVTSDRLNTHTLPSYTLV
DMVVGYDLSSIGLNGLSAQLNVNNLTDKRYVAACNSLSYCYFGAERSIVGSVSWAF
>Mature_696_residues
MFATTRMALLIGGAIGGATFPLFAQETTKNDTVIVTSPVQSGATRLATPDIETPQSVSIITRQQFEEQGATSVRQAVSYT
PGVYSNQIGASNRFDYIVLRGFSDGSLDNVYLDGLKMMGDTNSHSSLVVDPWFLEDIEVVRGPASVLYGRSSPGGIVSLT
SRKPAFDAGGEVKLFAGNNNQRGAAFDVTGPLDDNERVAARLSGMTRYADSQFTPLKEERYALMPSLTWRITDRTRLDLM
AYLHRDPQGGSHSGLPYQGTVVPYNGGKISNTFFEGEDDYDKYDRRENMVGYNIEHLFDNGWSVRQKLRYLHTKVTLNQV
YAAGWLNETALNRGYSGSGEKMSAIALDNQLDGSVDTGAINHRLLVGIDYQDRSNHTTGYYGAFPPIDAFNPVYGAQPDY
ITLYSREKHKLRQTGYYLQDQMSWDRWRFTLGGRYDRVSVSNIDKLHDSRSDLDKNNVSTRAALLYLFDNGVAPYLSYST
AFTSTSFADENGNVLEPMKGKQWEAGVKYEPLGGNSQFSAAVYRINQTNIATKEEPTDPYRSIGEIESKGVELEAISHLS
DSVRLQAAYTYTDIRYKKSSPQEQGKRAVYAPRNQASAWLSYDVKSGLLEWLTLGSGIRYVNGVTSDRLNTHTLPSYTLV
DMVVGYDLSSIGLNGLSAQLNVNNLTDKRYVAACNSLSYCYFGAERSIVGSVSWAF

Specific function: Ferrioxamine binding and uptake, in association with the tonB protein. May play a role in intestinal colonization [H]

COG id: COG1629

COG function: function code P; Outer membrane receptor proteins, mostly Fe transport

Gene ontology:

Cell location: Cell outer membrane [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tonB-dependent receptor family [H]

Homologues:

Organism=Escherichia coli, GI1786344, Length=738, Percent_Identity=35.9078590785908, Blast_Score=441, Evalue=1e-125,
Organism=Escherichia coli, GI1787024, Length=744, Percent_Identity=24.0591397849462, Blast_Score=128, Evalue=1e-30,
Organism=Escherichia coli, GI1787344, Length=723, Percent_Identity=24.6196403872752, Blast_Score=127, Evalue=3e-30,
Organism=Escherichia coli, GI1790743, Length=656, Percent_Identity=21.7987804878049, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI1790405, Length=195, Percent_Identity=27.1794871794872, Blast_Score=62, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012910
- InterPro:   IPR000531
- InterPro:   IPR010105 [H]

Pfam domain/function: PF07715 Plug; PF00593 TonB_dep_Rec [H]

EC number: NA

Molecular weight: Translated: 77132; Mature: 77132

Theoretical pI: Translated: 6.01; Mature: 6.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFATTRMALLIGGAIGGATFPLFAQETTKNDTVIVTSPVQSGATRLATPDIETPQSVSII
CCCCCEEEEEEECCCCCCCCEEEEECCCCCCEEEEECCCCCCCCEECCCCCCCCCCEEHH
TRQQFEEQGATSVRQAVSYTPGVYSNQIGASNRFDYIVLRGFSDGSLDNVYLDGLKMMGD
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEECCEEEECC
TNSHSSLVVDPWFLEDIEVVRGPASVLYGRSSPGGIVSLTSRKPAFDAGGEVKLFAGNNN
CCCCCEEEECCHHHHHHHHHCCCHHHEECCCCCCCEEEECCCCCCCCCCCCEEEEECCCC
QRGAAFDVTGPLDDNERVAARLSGMTRYADSQFTPLKEERYALMPSLTWRITDRTRLDLM
CCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHEEECCCEEEEECCCHHHHHH
AYLHRDPQGGSHSGLPYQGTVVPYNGGKISNTFFEGEDDYDKYDRRENMVGYNIEHLFDN
HHHHCCCCCCCCCCCCCCCEEEEECCCEEECCEECCCCCHHHHHHHCCCCCCCHHHHHCC
GWSVRQKLRYLHTKVTLNQVYAAGWLNETALNRGYSGSGEKMSAIALDNQLDGSVDTGAI
CHHHHHHHHHHHHHEEHHHHHHHCCCCHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCC
NHRLLVGIDYQDRSNHTTGYYGAFPPIDAFNPVYGAQPDYITLYSREKHKLRQTGYYLQD
CCEEEEEEECCCCCCCCCEEECCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHCCCEEHH
QMSWDRWRFTLGGRYDRVSVSNIDKLHDSRSDLDKNNVSTRAALLYLFDNGVAPYLSYST
CCCCCCEEEEECCCCCEEEHHHHHHHHCCHHHCCCCCCCCEEEEEEEECCCCCCCEEEHH
AFTSTSFADENGNVLEPMKGKQWEAGVKYEPLGGNSQFSAAVYRINQTNIATKEEPTDPY
HCCCCCCCCCCCCEECCCCCCCCCCCCEECCCCCCCCEEEEEEEEECCCCCCCCCCCCHH
RSIGEIESKGVELEAISHLSDSVRLQAAYTYTDIRYKKSSPQEQGKRAVYAPRNQASAWL
HHHHHHHHCCEEEEHHHHCCCCEEEEEEEEEEEEEECCCCCHHHCCEEEECCCCCCCEEE
SYDVKSGLLEWLTLGSGIRYVNGVTSDRLNTHTLPSYTLVDMVVGYDLSSIGLNGLSAQL
EEHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCHHHHHHHHCCCHHHCCCCCEEEEE
NVNNLTDKRYVAACNSLSYCYFGAERSIVGSVSWAF
ECCCCCCCHHHHHHCCCEEEEECCCCCEEEEEEECC
>Mature Secondary Structure
MFATTRMALLIGGAIGGATFPLFAQETTKNDTVIVTSPVQSGATRLATPDIETPQSVSII
CCCCCEEEEEEECCCCCCCCEEEEECCCCCCEEEEECCCCCCCCEECCCCCCCCCCEEHH
TRQQFEEQGATSVRQAVSYTPGVYSNQIGASNRFDYIVLRGFSDGSLDNVYLDGLKMMGD
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEECCEEEECC
TNSHSSLVVDPWFLEDIEVVRGPASVLYGRSSPGGIVSLTSRKPAFDAGGEVKLFAGNNN
CCCCCEEEECCHHHHHHHHHCCCHHHEECCCCCCCEEEECCCCCCCCCCCCEEEEECCCC
QRGAAFDVTGPLDDNERVAARLSGMTRYADSQFTPLKEERYALMPSLTWRITDRTRLDLM
CCCEEEEECCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHEEECCCEEEEECCCHHHHHH
AYLHRDPQGGSHSGLPYQGTVVPYNGGKISNTFFEGEDDYDKYDRRENMVGYNIEHLFDN
HHHHCCCCCCCCCCCCCCCEEEEECCCEEECCEECCCCCHHHHHHHCCCCCCCHHHHHCC
GWSVRQKLRYLHTKVTLNQVYAAGWLNETALNRGYSGSGEKMSAIALDNQLDGSVDTGAI
CHHHHHHHHHHHHHEEHHHHHHHCCCCHHHHCCCCCCCCCEEEEEEECCCCCCCCCCCCC
NHRLLVGIDYQDRSNHTTGYYGAFPPIDAFNPVYGAQPDYITLYSREKHKLRQTGYYLQD
CCEEEEEEECCCCCCCCCEEECCCCCCCCCCCCCCCCCCEEEEECCCHHHHHHCCCEEHH
QMSWDRWRFTLGGRYDRVSVSNIDKLHDSRSDLDKNNVSTRAALLYLFDNGVAPYLSYST
CCCCCCEEEEECCCCCEEEHHHHHHHHCCHHHCCCCCCCCEEEEEEEECCCCCCCEEEHH
AFTSTSFADENGNVLEPMKGKQWEAGVKYEPLGGNSQFSAAVYRINQTNIATKEEPTDPY
HCCCCCCCCCCCCEECCCCCCCCCCCCEECCCCCCCCEEEEEEEEECCCCCCCCCCCCHH
RSIGEIESKGVELEAISHLSDSVRLQAAYTYTDIRYKKSSPQEQGKRAVYAPRNQASAWL
HHHHHHHHCCEEEEHHHHCCCCEEEEEEEEEEEEEECCCCCHHHCCEEEECCCCCCCEEE
SYDVKSGLLEWLTLGSGIRYVNGVTSDRLNTHTLPSYTLVDMVVGYDLSSIGLNGLSAQL
EEHHHHHHHHHHHHCCCCEEECCCCCCCCCCCCCCCHHHHHHHHCCCHHHCCCCCEEEEE
NVNNLTDKRYVAACNSLSYCYFGAERSIVGSVSWAF
ECCCCCCCHHHHHHCCCEEEEECCCCCEEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677609; 10103258; 7642488 [H]