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The map label for this gene is hcpE [H]

Identifier: 29142810

GI number: 29142810

Start: 2495647

End: 2496801

Strand: Reverse

Name: hcpE [H]

Synonym: t2422

Alternate gene names: 29142810

Gene position: 2496801-2495647 (Counterclockwise)

Preceding gene: 29142811

Following gene: 29142802

Centisome position: 52.1

GC content: 50.82

Gene sequence:

>1155_bases
ATGCAGGATGACGTTTTGGCAAAAGAGCTTGCGGATAAAACCAGTAAAGCAGATATCGATACTGATGCGCAGACGGTGAC
GCGCCTGATAGCCGACGAAATAGATACGGCAAAGCAAGCCGCGGAAAGCGATATTACTCAGCGTTCCCGGTTTATTGAAA
CATTACGCCAGTATGCCGGCGGCGGGAGCGCGATGGCCGCGCGCATCACGCGCCTGGGTTATTCAAAGGCGGATATCCTG
CACCTTGCGGAGCTGTGGGCGCAGGAGAGAGACCCTGAACTTAACTTTATCGTTGGTAGTCTCTATGACTCTGGTTTTGT
TGAGGTCGACGATAAAGAGGCGCGTTCGTTGCAATGGTTCCGCAAGGCTGCTGAATTGGGCCAGGCTGATGCGCAGAATA
TACTCGGTTACTTCTACTTGAATGGAAAACGAGGGATTAAGCGCGATCTGCAGAAGGGGGGGCAGTGGTACGAGTTGGCG
GCTGCGCAGGGTAATGTCGATGCGCTCATAAATCTTGGTGAGATCTATTACTCCGGGACGCGGGTTCCGCTTGATTACGC
TCGGGCGTTTGAATTCTTTGAACGGGCGGCGAAGATGGGCAAGTCTCGCGCTTTAAACTATCTTGCCTGGATGTATACCA
ACGGTCAGTTTGTCGACACGGACTGCCGGAAGGCAGCGGAGTTGTTTGCTCAGGGGCGAACAAGTTTTGCAGACGATCCC
CATTTTCAGGTGACCTGCGAAAAAGACCGACAGGCCCGTGCTGAGGCTGTGGCAATGCGTGAAAAGAATTTGCCGAAGTT
AACCTTCAATCGTGATCGTGTTTTCGGTGCGAGTCAGGGCAGCGGCTATGCATGCGAGCTGGAGTTTGTCGTCAAAACGG
ATAGAGTCAGCAGTATAGAGAATTTACGCGTCTCACTGGCGCTGAAAAATAAGGCCGGGGCGATGTCACAGCAGGTTATC
GCATTTGAGCCTTTTGGGCTAAATATGCAGAACCGCAATTTACAAGGGTATAAGTCTGATACGCTACGTGAATCGACATT
ACAACCTATCTATCAGCCGGAATTTTGCGATGTTGATAGCTATAGCGTAACCGCTGTGACGGGGATTGTTAACGGTAAAG
AGATGGACATTCTTAAGGCGGGAATTTTTATTTAA

Upstream 100 bases:

>100_bases
TACGATACAGGCTATCAAGTATTATGAGCAGGCTTGTCATGTTGAATAACCCTATGGCTGCTACAACGCTCGTTATTTTT
ATCTGCATGGCCTGGGGGTG

Downstream 100 bases:

>100_bases
ACGCGAAAAGAAAGATGGCGTATCAAGCGATACGCCATCTAAAGTCTTTACCAGACGTAAGTCAGCAGATTCTGCGAATT
CGGCACCATAAAATCAACAG

Product: hypothetical protein

Products: NA

Alternate protein names: Cysteine-rich protein E [H]

Number of amino acids: Translated: 384; Mature: 384

Protein sequence:

>384_residues
MQDDVLAKELADKTSKADIDTDAQTVTRLIADEIDTAKQAAESDITQRSRFIETLRQYAGGGSAMAARITRLGYSKADIL
HLAELWAQERDPELNFIVGSLYDSGFVEVDDKEARSLQWFRKAAELGQADAQNILGYFYLNGKRGIKRDLQKGGQWYELA
AAQGNVDALINLGEIYYSGTRVPLDYARAFEFFERAAKMGKSRALNYLAWMYTNGQFVDTDCRKAAELFAQGRTSFADDP
HFQVTCEKDRQARAEAVAMREKNLPKLTFNRDRVFGASQGSGYACELEFVVKTDRVSSIENLRVSLALKNKAGAMSQQVI
AFEPFGLNMQNRNLQGYKSDTLRESTLQPIYQPEFCDVDSYSVTAVTGIVNGKEMDILKAGIFI

Sequences:

>Translated_384_residues
MQDDVLAKELADKTSKADIDTDAQTVTRLIADEIDTAKQAAESDITQRSRFIETLRQYAGGGSAMAARITRLGYSKADIL
HLAELWAQERDPELNFIVGSLYDSGFVEVDDKEARSLQWFRKAAELGQADAQNILGYFYLNGKRGIKRDLQKGGQWYELA
AAQGNVDALINLGEIYYSGTRVPLDYARAFEFFERAAKMGKSRALNYLAWMYTNGQFVDTDCRKAAELFAQGRTSFADDP
HFQVTCEKDRQARAEAVAMREKNLPKLTFNRDRVFGASQGSGYACELEFVVKTDRVSSIENLRVSLALKNKAGAMSQQVI
AFEPFGLNMQNRNLQGYKSDTLRESTLQPIYQPEFCDVDSYSVTAVTGIVNGKEMDILKAGIFI
>Mature_384_residues
MQDDVLAKELADKTSKADIDTDAQTVTRLIADEIDTAKQAAESDITQRSRFIETLRQYAGGGSAMAARITRLGYSKADIL
HLAELWAQERDPELNFIVGSLYDSGFVEVDDKEARSLQWFRKAAELGQADAQNILGYFYLNGKRGIKRDLQKGGQWYELA
AAQGNVDALINLGEIYYSGTRVPLDYARAFEFFERAAKMGKSRALNYLAWMYTNGQFVDTDCRKAAELFAQGRTSFADDP
HFQVTCEKDRQARAEAVAMREKNLPKLTFNRDRVFGASQGSGYACELEFVVKTDRVSSIENLRVSLALKNKAGAMSQQVI
AFEPFGLNMQNRNLQGYKSDTLRESTLQPIYQPEFCDVDSYSVTAVTGIVNGKEMDILKAGIFI

Specific function: May hydrolyze 6-aminopenicillinic acid and 7- aminocephalosporanic acid (ACA) derivatives [H]

COG id: COG0790

COG function: function code R; FOG: TPR repeat, SEL1 subfamily

Gene ontology:

Cell location: Secreted (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 8 TPR repeats [H]

Homologues:

Organism=Homo sapiens, GI151301150, Length=152, Percent_Identity=30.9210526315789, Blast_Score=82, Evalue=8e-16,
Organism=Homo sapiens, GI19923669, Length=133, Percent_Identity=35.3383458646617, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI87081769, Length=117, Percent_Identity=36.7521367521368, Blast_Score=72, Evalue=8e-14,
Organism=Caenorhabditis elegans, GI17563256, Length=142, Percent_Identity=30.9859154929577, Blast_Score=65, Evalue=5e-11,
Organism=Drosophila melanogaster, GI21355295, Length=133, Percent_Identity=33.8345864661654, Blast_Score=69, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006597
- InterPro:   IPR011990 [H]

Pfam domain/function: PF08238 Sel1 [H]

EC number: =3.5.2.6 [H]

Molecular weight: Translated: 42955; Mature: 42955

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQDDVLAKELADKTSKADIDTDAQTVTRLIADEIDTAKQAAESDITQRSRFIETLRQYAG
CCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GGSAMAARITRLGYSKADILHLAELWAQERDPELNFIVGSLYDSGFVEVDDKEARSLQWF
CCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEECCHHHHHHHHH
RKAAELGQADAQNILGYFYLNGKRGIKRDLQKGGQWYELAAAQGNVDALINLGEIYYSGT
HHHHHHCCCCHHCCEEEEEECCCCHHHHHHHCCCCEEEEEECCCCHHHEEEECHHEECCC
RVPLDYARAFEFFERAAKMGKSRALNYLAWMYTNGQFVDTDCRKAAELFAQGRTSFADDP
CCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCEEECHHHHHHHHHHHCCCCCCCCCC
HFQVTCEKDRQARAEAVAMREKNLPKLTFNRDRVFGASQGSGYACELEFVVKTDRVSSIE
CEEEEECCHHHHHHHHHHHHHCCCCCEEECCCEEEECCCCCCEEEEEEEEEECCHHHHHH
NLRVSLALKNKAGAMSQQVIAFEPFGLNMQNRNLQGYKSDTLRESTLQPIYQPEFCDVDS
HEEEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCC
YSVTAVTGIVNGKEMDILKAGIFI
CEEEEEEEECCCCHHHHHHCCCCC
>Mature Secondary Structure
MQDDVLAKELADKTSKADIDTDAQTVTRLIADEIDTAKQAAESDITQRSRFIETLRQYAG
CCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GGSAMAARITRLGYSKADILHLAELWAQERDPELNFIVGSLYDSGFVEVDDKEARSLQWF
CCHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCEEECCHHHHHHHHH
RKAAELGQADAQNILGYFYLNGKRGIKRDLQKGGQWYELAAAQGNVDALINLGEIYYSGT
HHHHHHCCCCHHCCEEEEEECCCCHHHHHHHCCCCEEEEEECCCCHHHEEEECHHEECCC
RVPLDYARAFEFFERAAKMGKSRALNYLAWMYTNGQFVDTDCRKAAELFAQGRTSFADDP
CCCHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCEEECHHHHHHHHHHHCCCCCCCCCC
HFQVTCEKDRQARAEAVAMREKNLPKLTFNRDRVFGASQGSGYACELEFVVKTDRVSSIE
CEEEEECCHHHHHHHHHHHHHCCCCCEEECCCEEEECCCCCCEEEEEEEEEECCHHHHHH
NLRVSLALKNKAGAMSQQVIAFEPFGLNMQNRNLQGYKSDTLRESTLQPIYQPEFCDVDS
HEEEEEEECCCCCCCCCEEEEECCCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCCCCCCC
YSVTAVTGIVNGKEMDILKAGIFI
CEEEEEEEECCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]