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The map label for this gene is clpX [H]

Identifier: 29142799

GI number: 29142799

Start: 2483597

End: 2484868

Strand: Reverse

Name: clpX [H]

Synonym: t2411

Alternate gene names: 29142799

Gene position: 2484868-2483597 (Counterclockwise)

Preceding gene: 29142800

Following gene: 29142798

Centisome position: 51.85

GC content: 53.07

Gene sequence:

>1272_bases
ATGACAGATAAACGCAAAGATGGCTCGGGCAAATTGTTGTACTGCTCTTTTTGCGGCAAAAGCCAGCATGAAGTGCGCAA
GCTGATTGCCGGTCCATCCGTGTATATCTGCGACGAATGCGTCGATTTATGTAACGACATTATTCGCGAAGAAATTAAAG
AAGTTGCTCCGCACCGTGAACGTAGTGCGCTGCCGACGCCGCATGAAATTCGTACTCACCTGGACGATTACGTTATCGGC
CAGGAGCAGGCGAAAAAAGTGCTGGCGGTGGCGGTCTATAACCACTACAAGCGTCTGCGTAACGGCGATACCAGCAATGG
CGTCGAGTTAGGCAAAAGCAACATTCTGCTGACTGGACCGACCGGTTCCGGTAAAACGCTGCTGGCGGAAACGCTGGCGC
GCTTGCTGGATGTGCCGTTCACTATGGCGGATGCGACCACGCTGACCGAAGCGGGTTACGTGGGGGAAGACGTCGAGAAT
ATCATTCAGAAACTGTTGCAGAAATGCGACTACGACGTGCAAAAAGCGCAGCGTGGGATTGTCTACATTGATGAAATCGA
TAAGATTTCGCGTAAATCAGACAATCCGTCCATTACCCGCGATGTTTCCGGCGAAGGCGTACAGCAGGCGTTGCTGAAAC
TGATCGAAGGCACCGTCGCCGCGGTTCCACCGCAGGGCGGTCGCAAACATCCGCAGCAGGAGTTCTTACAGGTAGATACC
TCTAAGATTCTGTTTATCTGCGGCGGCGCGTTTGCCGGTCTGGATAAAGTGATCGCTAACCGTGTTGAAACCGGCTCCGG
CATTGGTTTTGGCGCGACGGTGAAAGCGAAGTCCGACAAAGCCAGTGAAGGCGAGCTGTTGTCGCAGGTTGAACCGGAAG
ATTTGATCAAATTTGGTCTGATTCCTGAGTTTATCGGTCGTCTGCCAGTGGTGGCGACGCTGAACGAACTCAGCGAAGAA
GCGCTGGTTCAAATCCTGAAAGAGCCGAAAAATGCGCTGACCAAGCAGTATCAGGCGCTGTTTAACCTGGAAGGCGTCGA
TCTGGAATTCCGTGACGAAGCGCTGAACGCTATCGCCAGGAAAGCGATGGCGCGTAAAACTGGTGCCCGTGGCCTGCGTT
CTATCGTCGAAGCGGCGCTGCTGGATACCATGTACGATTTGCCATCTATGGAAGACGTCGAAAAAGTGGTGATTGACGAG
TCCGTTATTGCCGGTCAGAGTAAGCCGTTGCTGATTTACGGCAAACCGGAAGCGCAGGCTTCTGGCGAATAA

Upstream 100 bases:

>100_bases
ACTAATGAAGGGCGGCACAACGCTGATTAGCGGCTTGCGCCTGAGAATGGCATTTGCGTCGTCGTGTGCGGCACAAAGAA
CAAAGAAGAGGTTTTGACTC

Downstream 100 bases:

>100_bases
TTAAACATTCATACAATCAGTTAGCCAAAAAAGGGGGGATTTTATCTCCCCTTTCGTTTTTCCTGTAAACACGCCGTTGA
ATGTGTGGGAAACATCCCCA

Product: ATP-dependent protease ATP-binding subunit ClpX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 422

Protein sequence:

>423_residues
MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVAPHRERSALPTPHEIRTHLDDYVIG
QEQAKKVLAVAVYNHYKRLRNGDTSNGVELGKSNILLTGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVEN
IIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVDT
SKILFICGGAFAGLDKVIANRVETGSGIGFGATVKAKSDKASEGELLSQVEPEDLIKFGLIPEFIGRLPVVATLNELSEE
ALVQILKEPKNALTKQYQALFNLEGVDLEFRDEALNAIARKAMARKTGARGLRSIVEAALLDTMYDLPSMEDVEKVVIDE
SVIAGQSKPLLIYGKPEAQASGE

Sequences:

>Translated_423_residues
MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVAPHRERSALPTPHEIRTHLDDYVIG
QEQAKKVLAVAVYNHYKRLRNGDTSNGVELGKSNILLTGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVEN
IIQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVDT
SKILFICGGAFAGLDKVIANRVETGSGIGFGATVKAKSDKASEGELLSQVEPEDLIKFGLIPEFIGRLPVVATLNELSEE
ALVQILKEPKNALTKQYQALFNLEGVDLEFRDEALNAIARKAMARKTGARGLRSIVEAALLDTMYDLPSMEDVEKVVIDE
SVIAGQSKPLLIYGKPEAQASGE
>Mature_422_residues
TDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVAPHRERSALPTPHEIRTHLDDYVIGQ
EQAKKVLAVAVYNHYKRLRNGDTSNGVELGKSNILLTGPTGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVENI
IQKLLQKCDYDVQKAQRGIVYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVDTS
KILFICGGAFAGLDKVIANRVETGSGIGFGATVKAKSDKASEGELLSQVEPEDLIKFGLIPEFIGRLPVVATLNELSEEA
LVQILKEPKNALTKQYQALFNLEGVDLEFRDEALNAIARKAMARKTGARGLRSIVEAALLDTMYDLPSMEDVEKVVIDES
VIAGQSKPLLIYGKPEAQASGE

Specific function: ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP [H]

COG id: COG1219

COG function: function code O; ATP-dependent protease Clp, ATPase subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ClpX chaperone family [H]

Homologues:

Organism=Homo sapiens, GI7242140, Length=342, Percent_Identity=51.1695906432749, Blast_Score=308, Evalue=6e-84,
Organism=Escherichia coli, GI1786642, Length=424, Percent_Identity=97.6415094339623, Blast_Score=839, Evalue=0.0,
Organism=Escherichia coli, GI1790366, Length=100, Percent_Identity=44, Blast_Score=92, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI71982908, Length=311, Percent_Identity=47.2668810289389, Blast_Score=275, Evalue=3e-74,
Organism=Caenorhabditis elegans, GI71982905, Length=311, Percent_Identity=47.2668810289389, Blast_Score=275, Evalue=3e-74,
Organism=Caenorhabditis elegans, GI71988663, Length=417, Percent_Identity=38.6091127098321, Blast_Score=249, Evalue=1e-66,
Organism=Caenorhabditis elegans, GI71988660, Length=256, Percent_Identity=40.234375, Blast_Score=177, Evalue=8e-45,
Organism=Saccharomyces cerevisiae, GI6319704, Length=427, Percent_Identity=40.2810304449649, Blast_Score=275, Evalue=8e-75,
Organism=Drosophila melanogaster, GI24648291, Length=320, Percent_Identity=48.4375, Blast_Score=291, Evalue=4e-79,
Organism=Drosophila melanogaster, GI24648289, Length=320, Percent_Identity=48.4375, Blast_Score=291, Evalue=5e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013093
- InterPro:   IPR019489
- InterPro:   IPR004487
- InterPro:   IPR010603 [H]

Pfam domain/function: PF07724 AAA_2; PF10431 ClpB_D2-small; PF06689 zf-C4_ClpX [H]

EC number: NA

Molecular weight: Translated: 46149; Mature: 46018

Theoretical pI: Translated: 5.07; Mature: 5.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVAPHRE
CCCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCC
RSALPTPHEIRTHLDDYVIGQEQAKKVLAVAVYNHYKRLRNGDTSNGVELGKSNILLTGP
CCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCEEEECC
TGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVQKAQRGI
CCCCHHHHHHHHHHHHCCCCHHHCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCCCC
VYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVDT
EEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEECCCCCCCCCCHHHHHHHCC
SKILFICGGAFAGLDKVIANRVETGSGIGFGATVKAKSDKASEGELLSQVEPEDLIKFGL
CEEEEEECCHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCHHHHCCCHHHHHHHCC
IPEFIGRLPVVATLNELSEEALVQILKEPKNALTKQYQALFNLEGVDLEFRDEALNAIAR
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
KAMARKTGARGLRSIVEAALLDTMYDLPSMEDVEKVVIDESVIAGQSKPLLIYGKPEAQA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCC
SGE
CCC
>Mature Secondary Structure 
TDKRKDGSGKLLYCSFCGKSQHEVRKLIAGPSVYICDECVDLCNDIIREEIKEVAPHRE
CCCCCCCCCCEEEEECCCCCHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHCCCCC
RSALPTPHEIRTHLDDYVIGQEQAKKVLAVAVYNHYKRLRNGDTSNGVELGKSNILLTGP
CCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEECCCCEEEECC
TGSGKTLLAETLARLLDVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVQKAQRGI
CCCCHHHHHHHHHHHHCCCCHHHCHHHHHHCCCCCHHHHHHHHHHHHHCCCCHHHHCCCC
VYIDEIDKISRKSDNPSITRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQVDT
EEEECHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHCCCCEECCCCCCCCCCHHHHHHHCC
SKILFICGGAFAGLDKVIANRVETGSGIGFGATVKAKSDKASEGELLSQVEPEDLIKFGL
CEEEEEECCHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCCCHHHHCCCHHHHHHHCC
IPEFIGRLPVVATLNELSEEALVQILKEPKNALTKQYQALFNLEGVDLEFRDEALNAIAR
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHH
KAMARKTGARGLRSIVEAALLDTMYDLPSMEDVEKVVIDESVIAGQSKPLLIYGKPEAQA
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCCEEEEECCCCCC
SGE
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA