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The map label for this gene is qmcA [H]

Identifier: 29142749

GI number: 29142749

Start: 2425538

End: 2426455

Strand: Direct

Name: qmcA [H]

Synonym: t2359

Alternate gene names: 29142749

Gene position: 2425538-2426455 (Clockwise)

Preceding gene: 29142746

Following gene: 29142750

Centisome position: 50.62

GC content: 54.68

Gene sequence:

>918_bases
ATGCTCATTCTTATCCCTATTCTCATTTTCGTCGCGCTGGTGATCGTCGGCGCGGGCGTCAAAATCGTTCCGCAGGGATA
CCAGTGGACGGTGGAGCGCTTTGGACGTTACACCAAAACTCTGCAGCCGGGATTAAGCCTTGTTGTACCGTTTATGGACA
GAATTGGCCGCAAGATCAATATGATGGAGCAGGTGCTGGATATTCCGTCGCAGGAGGTGATCTCAAAAGATAACGCCAAC
GTCACTATCGATGCGGTCTGTTTTATTCAGGTTATCGATGCGCCGCGCGCCGCTTATGAAGTCAGTAACCTGGAACTGGC
GATCATTAACCTGACCATGACCAATATCCGTACGGTGCTCGGTTCGATGGAGCTGGATGAAATGCTCTCCCAGCGCGACA
GCATCAACGCGCGGCTGCTGCATATTGTCGATGAAGCCACCAATCCGTGGGGAATTAAAGTTACCCGTATCGAAATTCGC
GATGTCCGTCCGCCCGCGGAATTGATCTCCTCGATGAACGCCCAGATGAAAGCGGAACGTACCAAACGCGCCTATATCCT
TGAGGCCGAAGGGGTGCGTCAGGCGGAAATCCTGAAAGCCGAGGGGGAAAAACAGTCGCAGATTCTGAAAGCCGAAGGCG
AACGTCAGTCCGCTTTCCTGCAGGCGGAAGCGCGCGAACGTTCCGCCGAAGCGGAAGCCCGCGCTACGCAGATGGTGTCT
GAAGCCATCGCCGCCGGGGATATTCAGGCGTTAAACTACTTCGTGGCGCAGAAATACACCGAAGCGTTACAGCAAATCGG
CTCGGCGAATAACAGCAAAGTGGTCATGATGCCGCTGGATGCCAGCAGTCTGATGGGCGCTATCGCCGGGATCAGCGAGC
TGGTTAAGGACAGCGCCAGCGAACGGAAAAAAGCATGA

Upstream 100 bases:

>100_bases
TGTAATTAATAAGGGGGGAACATGCTTTACTGAATCAGGTATAATTCGCTTAATTCGTCAGCAAAATCGGTTTATGGACA
ACGCAACAGGAGGTTTAGCT

Downstream 100 bases:

>100_bases
TAGCGATGATTCTGGTACATCCACATATCTTCTGGCTTAGCCTCGGCGGCCTGTTGTTGGCTGCGGAAATGCTCGGCGGT
AACGGCTATTTGCTGTGGAG

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 305

Protein sequence:

>305_residues
MLILIPILIFVALVIVGAGVKIVPQGYQWTVERFGRYTKTLQPGLSLVVPFMDRIGRKINMMEQVLDIPSQEVISKDNAN
VTIDAVCFIQVIDAPRAAYEVSNLELAIINLTMTNIRTVLGSMELDEMLSQRDSINARLLHIVDEATNPWGIKVTRIEIR
DVRPPAELISSMNAQMKAERTKRAYILEAEGVRQAEILKAEGEKQSQILKAEGERQSAFLQAEARERSAEAEARATQMVS
EAIAAGDIQALNYFVAQKYTEALQQIGSANNSKVVMMPLDASSLMGAIAGISELVKDSASERKKA

Sequences:

>Translated_305_residues
MLILIPILIFVALVIVGAGVKIVPQGYQWTVERFGRYTKTLQPGLSLVVPFMDRIGRKINMMEQVLDIPSQEVISKDNAN
VTIDAVCFIQVIDAPRAAYEVSNLELAIINLTMTNIRTVLGSMELDEMLSQRDSINARLLHIVDEATNPWGIKVTRIEIR
DVRPPAELISSMNAQMKAERTKRAYILEAEGVRQAEILKAEGEKQSQILKAEGERQSAFLQAEARERSAEAEARATQMVS
EAIAAGDIQALNYFVAQKYTEALQQIGSANNSKVVMMPLDASSLMGAIAGISELVKDSASERKKA
>Mature_305_residues
MLILIPILIFVALVIVGAGVKIVPQGYQWTVERFGRYTKTLQPGLSLVVPFMDRIGRKINMMEQVLDIPSQEVISKDNAN
VTIDAVCFIQVIDAPRAAYEVSNLELAIINLTMTNIRTVLGSMELDEMLSQRDSINARLLHIVDEATNPWGIKVTRIEIR
DVRPPAELISSMNAQMKAERTKRAYILEAEGVRQAEILKAEGEKQSQILKAEGERQSAFLQAEARERSAEAEARATQMVS
EAIAAGDIQALNYFVAQKYTEALQQIGSANNSKVVMMPLDASSLMGAIAGISELVKDSASERKKA

Specific function: Unknown

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family [H]

Homologues:

Organism=Homo sapiens, GI7305503, Length=275, Percent_Identity=34.5454545454545, Blast_Score=176, Evalue=2e-44,
Organism=Homo sapiens, GI21686995, Length=193, Percent_Identity=34.7150259067358, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI221316744, Length=193, Percent_Identity=34.7150259067358, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI38016911, Length=192, Percent_Identity=33.8541666666667, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI7657615, Length=185, Percent_Identity=31.3513513513514, Blast_Score=85, Evalue=7e-17,
Organism=Escherichia coli, GI1786697, Length=304, Percent_Identity=94.7368421052632, Blast_Score=588, Evalue=1e-169,
Organism=Caenorhabditis elegans, GI32564147, Length=299, Percent_Identity=35.4515050167224, Blast_Score=177, Evalue=6e-45,
Organism=Caenorhabditis elegans, GI17569493, Length=217, Percent_Identity=35.9447004608295, Blast_Score=122, Evalue=2e-28,
Organism=Caenorhabditis elegans, GI193209764, Length=187, Percent_Identity=37.4331550802139, Blast_Score=122, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI71987612, Length=198, Percent_Identity=34.8484848484849, Blast_Score=107, Evalue=7e-24,
Organism=Caenorhabditis elegans, GI25153583, Length=198, Percent_Identity=34.8484848484849, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71989948, Length=155, Percent_Identity=36.1290322580645, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI71989955, Length=155, Percent_Identity=36.1290322580645, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17569497, Length=193, Percent_Identity=30.0518134715026, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI71987621, Length=198, Percent_Identity=34.8484848484849, Blast_Score=105, Evalue=4e-23,
Organism=Caenorhabditis elegans, GI17569499, Length=193, Percent_Identity=34.1968911917098, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI17570459, Length=203, Percent_Identity=33.9901477832512, Blast_Score=98, Evalue=5e-21,
Organism=Caenorhabditis elegans, GI32566490, Length=188, Percent_Identity=34.0425531914894, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI193210507, Length=195, Percent_Identity=34.3589743589744, Blast_Score=91, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI17570161, Length=195, Percent_Identity=34.3589743589744, Blast_Score=91, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI71989963, Length=118, Percent_Identity=33.0508474576271, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI45550506, Length=275, Percent_Identity=36.7272727272727, Blast_Score=186, Evalue=2e-47,
Organism=Drosophila melanogaster, GI45556022, Length=193, Percent_Identity=34.7150259067358, Blast_Score=105, Evalue=3e-23,
Organism=Drosophila melanogaster, GI62484448, Length=197, Percent_Identity=32.994923857868, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI281365664, Length=197, Percent_Identity=32.994923857868, Blast_Score=100, Evalue=1e-21,
Organism=Drosophila melanogaster, GI62484274, Length=197, Percent_Identity=32.994923857868, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI24657857, Length=199, Percent_Identity=35.1758793969849, Blast_Score=100, Evalue=2e-21,
Organism=Drosophila melanogaster, GI18860517, Length=196, Percent_Identity=30.6122448979592, Blast_Score=99, Evalue=3e-21,
Organism=Drosophila melanogaster, GI21356845, Length=191, Percent_Identity=27.2251308900524, Blast_Score=89, Evalue=4e-18,
Organism=Drosophila melanogaster, GI281361631, Length=194, Percent_Identity=26.8041237113402, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI281361633, Length=192, Percent_Identity=27.0833333333333, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI28573263, Length=153, Percent_Identity=28.7581699346405, Blast_Score=80, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR018080
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: NA

Molecular weight: Translated: 33630; Mature: 33630

Theoretical pI: Translated: 5.11; Mature: 5.11

Prosite motif: PS01270 BAND_7

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
4.3 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLILIPILIFVALVIVGAGVKIVPQGYQWTVERFGRYTKTLQPGLSLVVPFMDRIGRKIN
CEEHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHH
MMEQVLDIPSQEVISKDNANVTIDAVCFIQVIDAPRAAYEVSNLELAIINLTMTNIRTVL
HHHHHHCCCCHHHHCCCCCCEEEEHEEEEHHHCCCHHHEEECCCEEEEEEEEHHHHHHHH
GSMELDEMLSQRDSINARLLHIVDEATNPWGIKVTRIEIRDVRPPAELISSMNAQMKAER
CCCCHHHHHHHHCCCCHHEEEEECCCCCCCCEEEEEEEEECCCCHHHHHHHHCHHHHHHH
TKRAYILEAEGVRQAEILKAEGEKQSQILKAEGERQSAFLQAEARERSAEAEARATQMVS
HHCEEEEECCCCCHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EAIAAGDIQALNYFVAQKYTEALQQIGSANNSKVVMMPLDASSLMGAIAGISELVKDSAS
HHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCHH
ERKKA
HHCCC
>Mature Secondary Structure
MLILIPILIFVALVIVGAGVKIVPQGYQWTVERFGRYTKTLQPGLSLVVPFMDRIGRKIN
CEEHHHHHHHHHHHHHCCCCEEECCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHH
MMEQVLDIPSQEVISKDNANVTIDAVCFIQVIDAPRAAYEVSNLELAIINLTMTNIRTVL
HHHHHHCCCCHHHHCCCCCCEEEEHEEEEHHHCCCHHHEEECCCEEEEEEEEHHHHHHHH
GSMELDEMLSQRDSINARLLHIVDEATNPWGIKVTRIEIRDVRPPAELISSMNAQMKAER
CCCCHHHHHHHHCCCCHHEEEEECCCCCCCCEEEEEEEEECCCCHHHHHHHHCHHHHHHH
TKRAYILEAEGVRQAEILKAEGEKQSQILKAEGERQSAFLQAEARERSAEAEARATQMVS
HHCEEEEECCCCCHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EAIAAGDIQALNYFVAQKYTEALQQIGSANNSKVVMMPLDASSLMGAIAGISELVKDSAS
HHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCEEEEEECCHHHHHHHHHHHHHHHHCCHH
ERKKA
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]