Click here to switch to the map view.

The map label for this gene is ybdL [H]

Identifier: 29142665

GI number: 29142665

Start: 2330932

End: 2332092

Strand: Reverse

Name: ybdL [H]

Synonym: t2265

Alternate gene names: 29142665

Gene position: 2332092-2330932 (Counterclockwise)

Preceding gene: 29142667

Following gene: 29142660

Centisome position: 48.67

GC content: 54.69

Gene sequence:

>1161_bases
ATGAGAAATAACCCACTGATTCCAAAGAGCAAATTGCCCAATCTTGGCACCACGATTTTTACGCAAATGAGCGCGCTGGC
GCAGAAACATCAGGCAATAAATTTATCGCAAGGCTTCCCTGATTTTGATGGTCCTTCTTATTTGCACGAGCGGTTGGCTT
ATCATGTCGCGCAGGGCGCGAATCAATATGCGCCGATGACGGGCGCGCAGGCGCTGCGGGAGGCCATAGCCGATAAAACG
GCGGAAATATATGGTTATCGACCCGATGACGTAAGTGATATCACCGTCACGGCGGGCGCGACAGAAGCGCTGTATGCGGC
GATTACCGCGCTGGTGCGGGCAGGGGATGAGGTTATCTGTTTCGATCCCAGTTACGACAGCTATGCCCCGGCCGTGGCGC
TTTCCGGCGGCGTGTTAAAACGCATAGCGCTTACGCCGCCGCATTTTCGCGTCGACTGGCAGGCGTTTTCGGCGTTGCTT
AGCGAGCGCACGCGGCTGGTGATCCTCAATACGCCGCATAATCCCACCGCTACCGTCTGGCGTCAGGCGGATATCGAGGC
GCTGTGGCAGGCTATCGGCGAGCGGGAAATTTATGTATTAAGCGATGAAGTGTACGAGCATATTTGTTTTGCCGCCGAAG
GTCATGCCAGCGTACTGGCGCACCCTCAGTTACGAGAGCGGGCGGTTGCCGTTTCATCGTTTGGTAAAACCTTTCATATG
ACGGGATGGAAGATTGGTTACTGCGTTGCGCCTGCGGCCATTAGCGCCGAAATACGCAAAGTTCACCAGTACCTGACGTT
TTGCGTCAATACGCCGGCGCAACTGGCGCTGGCGGATATGCTGCGCGCCGCGCCGGAACACTATCGCGCGTTACCCGATT
TTTACCGGAAAAAACGCGATGTGCTGGTTAACGCGCTGGCGCAAAGCCGATTAAAAGTGCTGCCCTGTGAAGGTACCTAT
TTTTTGTTAATCGATTACAGCGCAGTGTCGACGCTAAATGACGTTGAGTTTTGTCAGTGGCTAACCGAAGAAGTCGGTGT
CGCCGCTATTCCGCTCTCTGTCTTTTGCGCCGCCCCTTTCCCGCATCAGCTTATACGTTTATGTTTCGCTAAACAGGAAT
CAACGCTGCTGGCCGCCGCAGAGCGCCTGTGTAAACTGTAG

Upstream 100 bases:

>100_bases
CCGCTGTTATTATATTTAGACATCTAAACGTCTTGATTGCCAAATACTAACACCCTGTGATAGTGTGTCAACAACCACAT
CACTGGCGGGTATGAAGATA

Downstream 100 bases:

>100_bases
TTATTTAACCGTCCACGCTCTGGAGAATCGACGGTCTGCAAAGAGTTCCTGCAGTCCGTTGATCTGTTTCAGGCGCAGGA
CTTCATCGGCGTCCATACCT

Product: aminotransferase

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 386; Mature: 386

Protein sequence:

>386_residues
MRNNPLIPKSKLPNLGTTIFTQMSALAQKHQAINLSQGFPDFDGPSYLHERLAYHVAQGANQYAPMTGAQALREAIADKT
AEIYGYRPDDVSDITVTAGATEALYAAITALVRAGDEVICFDPSYDSYAPAVALSGGVLKRIALTPPHFRVDWQAFSALL
SERTRLVILNTPHNPTATVWRQADIEALWQAIGEREIYVLSDEVYEHICFAAEGHASVLAHPQLRERAVAVSSFGKTFHM
TGWKIGYCVAPAAISAEIRKVHQYLTFCVNTPAQLALADMLRAAPEHYRALPDFYRKKRDVLVNALAQSRLKVLPCEGTY
FLLIDYSAVSTLNDVEFCQWLTEEVGVAAIPLSVFCAAPFPHQLIRLCFAKQESTLLAAAERLCKL

Sequences:

>Translated_386_residues
MRNNPLIPKSKLPNLGTTIFTQMSALAQKHQAINLSQGFPDFDGPSYLHERLAYHVAQGANQYAPMTGAQALREAIADKT
AEIYGYRPDDVSDITVTAGATEALYAAITALVRAGDEVICFDPSYDSYAPAVALSGGVLKRIALTPPHFRVDWQAFSALL
SERTRLVILNTPHNPTATVWRQADIEALWQAIGEREIYVLSDEVYEHICFAAEGHASVLAHPQLRERAVAVSSFGKTFHM
TGWKIGYCVAPAAISAEIRKVHQYLTFCVNTPAQLALADMLRAAPEHYRALPDFYRKKRDVLVNALAQSRLKVLPCEGTY
FLLIDYSAVSTLNDVEFCQWLTEEVGVAAIPLSVFCAAPFPHQLIRLCFAKQESTLLAAAERLCKL
>Mature_386_residues
MRNNPLIPKSKLPNLGTTIFTQMSALAQKHQAINLSQGFPDFDGPSYLHERLAYHVAQGANQYAPMTGAQALREAIADKT
AEIYGYRPDDVSDITVTAGATEALYAAITALVRAGDEVICFDPSYDSYAPAVALSGGVLKRIALTPPHFRVDWQAFSALL
SERTRLVILNTPHNPTATVWRQADIEALWQAIGEREIYVLSDEVYEHICFAAEGHASVLAHPQLRERAVAVSSFGKTFHM
TGWKIGYCVAPAAISAEIRKVHQYLTFCVNTPAQLALADMLRAAPEHYRALPDFYRKKRDVLVNALAQSRLKVLPCEGTY
FLLIDYSAVSTLNDVEFCQWLTEEVGVAAIPLSVFCAAPFPHQLIRLCFAKQESTLLAAAERLCKL

Specific function: Shows aminotransferase activity with methionine and histidine as substrates, and to a lesser extent also with phenylalanine [H]

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI95147551, Length=410, Percent_Identity=30.7317073170732, Blast_Score=214, Evalue=1e-55,
Organism=Homo sapiens, GI169881279, Length=410, Percent_Identity=30.7317073170732, Blast_Score=214, Evalue=1e-55,
Organism=Homo sapiens, GI56713254, Length=401, Percent_Identity=31.9201995012469, Blast_Score=210, Evalue=2e-54,
Organism=Homo sapiens, GI56713256, Length=401, Percent_Identity=31.9201995012469, Blast_Score=210, Evalue=2e-54,
Organism=Homo sapiens, GI169881281, Length=410, Percent_Identity=26.8292682926829, Blast_Score=161, Evalue=1e-39,
Organism=Homo sapiens, GI4507369, Length=338, Percent_Identity=23.9644970414201, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI1786816, Length=386, Percent_Identity=85.2331606217617, Blast_Score=693, Evalue=0.0,
Organism=Escherichia coli, GI1788722, Length=337, Percent_Identity=25.5192878338279, Blast_Score=104, Evalue=1e-23,
Organism=Escherichia coli, GI1788627, Length=308, Percent_Identity=25, Blast_Score=78, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI71994476, Length=413, Percent_Identity=30.5084745762712, Blast_Score=206, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI71994472, Length=413, Percent_Identity=30.5084745762712, Blast_Score=206, Evalue=1e-53,
Organism=Caenorhabditis elegans, GI17567369, Length=404, Percent_Identity=27.7227722772277, Blast_Score=187, Evalue=1e-47,
Organism=Caenorhabditis elegans, GI17567663, Length=346, Percent_Identity=23.6994219653179, Blast_Score=99, Evalue=4e-21,
Organism=Saccharomyces cerevisiae, GI6322401, Length=392, Percent_Identity=29.5918367346939, Blast_Score=175, Evalue=9e-45,
Organism=Drosophila melanogaster, GI28573069, Length=412, Percent_Identity=32.7669902912621, Blast_Score=223, Evalue=2e-58,
Organism=Drosophila melanogaster, GI24646114, Length=412, Percent_Identity=32.7669902912621, Blast_Score=223, Evalue=2e-58,
Organism=Drosophila melanogaster, GI28573067, Length=412, Percent_Identity=32.7669902912621, Blast_Score=223, Evalue=2e-58,
Organism=Drosophila melanogaster, GI28573065, Length=412, Percent_Identity=32.7669902912621, Blast_Score=223, Evalue=2e-58,
Organism=Drosophila melanogaster, GI18859735, Length=313, Percent_Identity=27.1565495207668, Blast_Score=81, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 42611; Mature: 42611

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRNNPLIPKSKLPNLGTTIFTQMSALAQKHQAINLSQGFPDFDGPSYLHERLAYHVAQGA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHHHHHHHHCC
NQYAPMTGAQALREAIADKTAEIYGYRPDDVSDITVTAGATEALYAAITALVRAGDEVIC
CCCCCCHHHHHHHHHHHHCHHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCEEEE
FDPSYDSYAPAVALSGGVLKRIALTPPHFRVDWQAFSALLSERTRLVILNTPHNPTATVW
ECCCCCCCCCHHHHCCHHHHHHCCCCCCCEECHHHHHHHHHCCCEEEEEECCCCCCHHHH
RQADIEALWQAIGEREIYVLSDEVYEHICFAAEGHASVLAHPQLRERAVAVSSFGKTFHM
HHHHHHHHHHHHCCCEEEEECHHHHHHHHHHCCCCHHEECCHHHHHHHHHHHHCCCEEEE
TGWKIGYCVAPAAISAEIRKVHQYLTFCVNTPAQLALADMLRAAPEHYRALPDFYRKKRD
CCCEEEHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHH
VLVNALAQSRLKVLPCEGTYFLLIDYSAVSTLNDVEFCQWLTEEVGVAAIPLSVFCAAPF
HHHHHHHHCCEEEEECCCEEEEEEECHHHHHHHHHHHHHHHHHHCCEEEECHHHHCCCCC
PHQLIRLCFAKQESTLLAAAERLCKL
HHHHHHHHHHCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MRNNPLIPKSKLPNLGTTIFTQMSALAQKHQAINLSQGFPDFDGPSYLHERLAYHVAQGA
CCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHEEECCCCCCCCCCHHHHHHHHHHHHHHCC
NQYAPMTGAQALREAIADKTAEIYGYRPDDVSDITVTAGATEALYAAITALVRAGDEVIC
CCCCCCHHHHHHHHHHHHCHHHHCCCCCCCCCCEEEECCCHHHHHHHHHHHHHCCCEEEE
FDPSYDSYAPAVALSGGVLKRIALTPPHFRVDWQAFSALLSERTRLVILNTPHNPTATVW
ECCCCCCCCCHHHHCCHHHHHHCCCCCCCEECHHHHHHHHHCCCEEEEEECCCCCCHHHH
RQADIEALWQAIGEREIYVLSDEVYEHICFAAEGHASVLAHPQLRERAVAVSSFGKTFHM
HHHHHHHHHHHHCCCEEEEECHHHHHHHHHHCCCCHHEECCHHHHHHHHHHHHCCCEEEE
TGWKIGYCVAPAAISAEIRKVHQYLTFCVNTPAQLALADMLRAAPEHYRALPDFYRKKRD
CCCEEEHHHCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCHHHHHHHHHHHHHHHH
VLVNALAQSRLKVLPCEGTYFLLIDYSAVSTLNDVEFCQWLTEEVGVAAIPLSVFCAAPF
HHHHHHHHCCEEEEECCCEEEEEEECHHHHHHHHHHHHHHHHHHCCEEEECHHHHCCCCC
PHQLIRLCFAKQESTLLAAAERLCKL
HHHHHHHHHHCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]