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The map label for this gene is yyaE [H]

Identifier: 29142656

GI number: 29142656

Start: 2320289

End: 2322568

Strand: Reverse

Name: yyaE [H]

Synonym: t2256

Alternate gene names: 29142656

Gene position: 2322568-2320289 (Counterclockwise)

Preceding gene: 29142657

Following gene: 29142655

Centisome position: 48.47

GC content: 54.47

Gene sequence:

>2280_bases
ATGAGTAATGAGACGGGACATCTGAACAGACGTTCTTTTTTAAAGGGGATAGTGGCGCTGGGCACCGTTGCGGCTTTACC
CGGAGGATTACTGACCTCCCGATGCGCGCTTGCGCAGCCGCCTGTTCCCTTTAACCCTAAAACGTACAAAATTTATCGTA
ACGCGTGTCCGCGTAACTGCTATGACACCTGTAGCCTCAAGACGTGGGTAAAGGACGGGGTCATTACTTTCGTGGAAGGT
GCGCCGGAATCAACATTTACTCACGGTACGCCTTACGTCAAAGGGTTGAGCTATCCGCGCCGGGTTTATAGTCCCGATCG
TATTAAATATCCCATGGCGCAGGACGTTCGCGGTAGCGGCAACTGGCGTCGCATCTCATGGGAAGAGGCGATGCAGCGTA
TTGCCGCCAAAATGCTGGAGATTAAGAAAAAAGACAGTTCTATGCTCGGTCTGGCGCTGACCAAATATTCCGGTAAGTTT
GGCGTGCTGAACTATGCCGTTGAAGGGATGATGTCCTCGCTTGGCTATACCACCCGTTTTGCCGGTACGCCGTGCTGGCC
TGCCGGTATTGACGCGCAAAACTACGACATGGGCGACATGTGGTGTAACGACCCGGAAGATATGGTGAAAGCAAAATACA
TCATTATCTGGGGCGCGAACCCAGCCTGGTGCTCAATGCACTCCATGAAATATATCTATCAGGCGCGCGAGAAAGGGGCG
AAGGTCGTGGTTATCGACCCGCTGCTGTCGCAGACTGCCGCCAAAGCCGATCTCTACCTGCGCGTACGGCCTGGCTCAGA
CGGCGCGCTGGCGCTGGGGATGGCGCGCCATCTGGTGGATAAGGGCCTGGTGGATCAGGATTTTGTCAACAACGACGCTC
ATGGCTATCCGGAATTTGAAGCCTATCTGCGTAACCATGTAACCGTGGAGTGGGCGGCAGAAATCTGCGGGTTGTCGGCA
CAGGTGATTCGTCAACTGGCGGAAGAGTTTACGGCGGTTAACCCGGCCACGGCCTGGATTGGTTACGGGATGCAGCGTCA
TGTCAACGGCGGCGCCAACGTTCGCGCTATCGATGCCTTTGTCGCTATGTCCGGCAACATCGGTGTCGAAGGCGGCGGCG
CGCGTTATGGCCATCTGCATACCTGGGGCTTTAACTATAACGCCATGCTGCAGAAGCCGCCGGTGGGCGCTATTGGCATA
CCGGGAGCGGCGGGCACCACCAGTGAATTCGGGGCTGCCGCTGGCAGCGACGCCGTGCAGTACTCCGATCGCTCTCTGAA
TATTAACCAGACGGCGCAGGGGATTCTGGAGGCCAACGATCCGCCGGTTCGTATGCTGTGGGTCGCCTGTAAAAACCCGT
TTGCCCAGGATTTCGATCGCAGCAAGATGAAAAAAGCGTTTGAAAAACTGGAAATGGTGGTCTGCGCCGATCAGTTCTTC
AACGAAACGGTGCAACACGCTGATATCGTGCTGCCCGTTACCACCGCGTTTGAAGAGTGGAACGTGGATGCTTCTTACTG
GCACTACTGGCTTTCCATTAATCAGCCGGCGATTAAGCCGATGTATGAAGCAAAATGCGACCTTGAAATCGCTACCATGC
TGTCGCGCACCATTAATAAGATGGCGCCGGGTTCCTGTACCTTCCCGCAAGAGTTCGATCACAAGCGCTGGCTGGATCAG
GAGTTCAACGACGGTATGGCGAAAATGTTCGGCATCTCTTCCTGGGACGATCTGCTGGACGGGCCAAAAAAAGCGATCCT
GCCAAGCTCTGCCGCCTGGTACGATCGCAAGTTCAAAACGCCGTCAGGCAAGTATGAATTTAAATCTGAACTGGCGGAGA
AAAACGGCCACACCGCGCTGCCGGAATACAAACCGGAAGCCGAGAGCAAACTGCCTTTCCATCTGTTTACGCCGCACGTG
CAGTTTGGCCTGCACTCGCAGTTTATCAACCTGGACTGGATGCAGGTGTTCTATCCGGAACCGTTTGTTTATATCCATCC
TTCTTCCGCGAAGAAAAAAGGCATTAGCGAAAATGACCGGGTCAAAGTTTTCAACAACATTGGCGAGGTGGAACTGCGGG
CAAAAGTCACCACCAACGTGCCGGAAGATTTTCTGGTGATGTATGAAGCGTGGTTCCCGAAACGGCAGTACAACGTGCAA
AACGTCGTGGCCGATACGCCTGCTGATATGGGGCTGATGAAAACTGGCGCGCCGGGCGCCGCTATCCACAGTCAGTTTGC
TGACGTTGTATTGATCGGTAAAGGGGAATCCGTAGCATGA

Upstream 100 bases:

>100_bases
TATATCGAAAAAATAAAAACTCATGCATAAACGACCACGTTATATACGGTGGCGGACATCTTATTTTATTGGTTTGATGA
ATTAAAACGAGAGTATCAAT

Downstream 100 bases:

>100_bases
GACGTGCGTTTTTAGTGAATAGCGATAAGTGCATCGGCTGCCGCGGCTGTGCTATGGCGTGTAAAAGCTTTAACCAACTG
GAGCCGGATCGCTTCTGGCG

Product: molybdopterin-containing oxidoreductase catalytic subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 759; Mature: 758

Protein sequence:

>759_residues
MSNETGHLNRRSFLKGIVALGTVAALPGGLLTSRCALAQPPVPFNPKTYKIYRNACPRNCYDTCSLKTWVKDGVITFVEG
APESTFTHGTPYVKGLSYPRRVYSPDRIKYPMAQDVRGSGNWRRISWEEAMQRIAAKMLEIKKKDSSMLGLALTKYSGKF
GVLNYAVEGMMSSLGYTTRFAGTPCWPAGIDAQNYDMGDMWCNDPEDMVKAKYIIIWGANPAWCSMHSMKYIYQAREKGA
KVVVIDPLLSQTAAKADLYLRVRPGSDGALALGMARHLVDKGLVDQDFVNNDAHGYPEFEAYLRNHVTVEWAAEICGLSA
QVIRQLAEEFTAVNPATAWIGYGMQRHVNGGANVRAIDAFVAMSGNIGVEGGGARYGHLHTWGFNYNAMLQKPPVGAIGI
PGAAGTTSEFGAAAGSDAVQYSDRSLNINQTAQGILEANDPPVRMLWVACKNPFAQDFDRSKMKKAFEKLEMVVCADQFF
NETVQHADIVLPVTTAFEEWNVDASYWHYWLSINQPAIKPMYEAKCDLEIATMLSRTINKMAPGSCTFPQEFDHKRWLDQ
EFNDGMAKMFGISSWDDLLDGPKKAILPSSAAWYDRKFKTPSGKYEFKSELAEKNGHTALPEYKPEAESKLPFHLFTPHV
QFGLHSQFINLDWMQVFYPEPFVYIHPSSAKKKGISENDRVKVFNNIGEVELRAKVTTNVPEDFLVMYEAWFPKRQYNVQ
NVVADTPADMGLMKTGAPGAAIHSQFADVVLIGKGESVA

Sequences:

>Translated_759_residues
MSNETGHLNRRSFLKGIVALGTVAALPGGLLTSRCALAQPPVPFNPKTYKIYRNACPRNCYDTCSLKTWVKDGVITFVEG
APESTFTHGTPYVKGLSYPRRVYSPDRIKYPMAQDVRGSGNWRRISWEEAMQRIAAKMLEIKKKDSSMLGLALTKYSGKF
GVLNYAVEGMMSSLGYTTRFAGTPCWPAGIDAQNYDMGDMWCNDPEDMVKAKYIIIWGANPAWCSMHSMKYIYQAREKGA
KVVVIDPLLSQTAAKADLYLRVRPGSDGALALGMARHLVDKGLVDQDFVNNDAHGYPEFEAYLRNHVTVEWAAEICGLSA
QVIRQLAEEFTAVNPATAWIGYGMQRHVNGGANVRAIDAFVAMSGNIGVEGGGARYGHLHTWGFNYNAMLQKPPVGAIGI
PGAAGTTSEFGAAAGSDAVQYSDRSLNINQTAQGILEANDPPVRMLWVACKNPFAQDFDRSKMKKAFEKLEMVVCADQFF
NETVQHADIVLPVTTAFEEWNVDASYWHYWLSINQPAIKPMYEAKCDLEIATMLSRTINKMAPGSCTFPQEFDHKRWLDQ
EFNDGMAKMFGISSWDDLLDGPKKAILPSSAAWYDRKFKTPSGKYEFKSELAEKNGHTALPEYKPEAESKLPFHLFTPHV
QFGLHSQFINLDWMQVFYPEPFVYIHPSSAKKKGISENDRVKVFNNIGEVELRAKVTTNVPEDFLVMYEAWFPKRQYNVQ
NVVADTPADMGLMKTGAPGAAIHSQFADVVLIGKGESVA
>Mature_758_residues
SNETGHLNRRSFLKGIVALGTVAALPGGLLTSRCALAQPPVPFNPKTYKIYRNACPRNCYDTCSLKTWVKDGVITFVEGA
PESTFTHGTPYVKGLSYPRRVYSPDRIKYPMAQDVRGSGNWRRISWEEAMQRIAAKMLEIKKKDSSMLGLALTKYSGKFG
VLNYAVEGMMSSLGYTTRFAGTPCWPAGIDAQNYDMGDMWCNDPEDMVKAKYIIIWGANPAWCSMHSMKYIYQAREKGAK
VVVIDPLLSQTAAKADLYLRVRPGSDGALALGMARHLVDKGLVDQDFVNNDAHGYPEFEAYLRNHVTVEWAAEICGLSAQ
VIRQLAEEFTAVNPATAWIGYGMQRHVNGGANVRAIDAFVAMSGNIGVEGGGARYGHLHTWGFNYNAMLQKPPVGAIGIP
GAAGTTSEFGAAAGSDAVQYSDRSLNINQTAQGILEANDPPVRMLWVACKNPFAQDFDRSKMKKAFEKLEMVVCADQFFN
ETVQHADIVLPVTTAFEEWNVDASYWHYWLSINQPAIKPMYEAKCDLEIATMLSRTINKMAPGSCTFPQEFDHKRWLDQE
FNDGMAKMFGISSWDDLLDGPKKAILPSSAAWYDRKFKTPSGKYEFKSELAEKNGHTALPEYKPEAESKLPFHLFTPHVQ
FGLHSQFINLDWMQVFYPEPFVYIHPSSAKKKGISENDRVKVFNNIGEVELRAKVTTNVPEDFLVMYEAWFPKRQYNVQN
VVADTPADMGLMKTGAPGAAIHSQFADVVLIGKGESVA

Specific function: Terminal Reductase During Anaerobic Growth On Various Sulfoxide And N-Oxide Compounds (By Similarity). [C]

COG id: COG0243

COG function: function code C; Anaerobic dehydrogenases, typically selenocysteine-containing

Gene ontology:

Cell location: Cytoplasm Face Of The Membrane [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the prokaryotic molybdopterin-containing oxidoreductase family [H]

Homologues:

Organism=Escherichia coli, GI1787870, Length=772, Percent_Identity=28.8860103626943, Blast_Score=236, Evalue=4e-63,
Organism=Escherichia coli, GI171474008, Length=768, Percent_Identity=28.7760416666667, Blast_Score=234, Evalue=2e-62,
Organism=Escherichia coli, GI87081797, Length=794, Percent_Identity=27.7078085642317, Blast_Score=229, Evalue=4e-61,
Organism=Escherichia coli, GI87081994, Length=716, Percent_Identity=26.1173184357542, Blast_Score=178, Evalue=1e-45,
Organism=Escherichia coli, GI145693196, Length=711, Percent_Identity=26.4416315049226, Blast_Score=176, Evalue=6e-45,
Organism=Escherichia coli, GI1787231, Length=735, Percent_Identity=26.3945578231293, Blast_Score=164, Evalue=1e-41,
Organism=Escherichia coli, GI3868721, Length=682, Percent_Identity=24.4868035190616, Blast_Score=134, Evalue=3e-32,
Organism=Escherichia coli, GI3868719, Length=491, Percent_Identity=24.2362525458248, Blast_Score=91, Evalue=4e-19,
Organism=Escherichia coli, GI3868720, Length=497, Percent_Identity=24.9496981891348, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1787778, Length=220, Percent_Identity=26.8181818181818, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009010
- InterPro:   IPR006657
- InterPro:   IPR006656
- InterPro:   IPR006963 [H]

Pfam domain/function: PF04879 Molybdop_Fe4S4; PF00384 Molybdopterin; PF01568 Molydop_binding [H]

EC number: 1.8.99.- [C]

Molecular weight: Translated: 84424; Mature: 84293

Theoretical pI: Translated: 7.40; Mature: 7.40

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNETGHLNRRSFLKGIVALGTVAALPGGLLTSRCALAQPPVPFNPKTYKIYRNACPRNC
CCCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCEEEEEECCCCCCC
YDTCSLKTWVKDGVITFVEGAPESTFTHGTPYVKGLSYPRRVYSPDRIKYPMAQDVRGSG
HHCCCHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCHHCCCCCC
NWRRISWEEAMQRIAAKMLEIKKKDSSMLGLALTKYSGKFGVLNYAVEGMMSSLGYTTRF
CEEEECHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCEEEC
AGTPCWPAGIDAQNYDMGDMWCNDPEDMVKAKYIIIWGANPAWCSMHSMKYIYQAREKGA
CCCCCCCCCCCCCCCCCCCCCCCCHHHHCEEEEEEEECCCCHHHHHHHHHHHHHHHHCCC
KVVVIDPLLSQTAAKADLYLRVRPGSDGALALGMARHLVDKGLVDQDFVNNDAHGYPEFE
EEEEECHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCHHHCCCCCCCCCHHH
AYLRNHVTVEWAAEICGLSAQVIRQLAEEFTAVNPATAWIGYGMQRHVNGGANVRAIDAF
HHHHHCCEEEEHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHCCHHEECCCCCCEEEEEEE
VAMSGNIGVEGGGARYGHLHTWGFNYNAMLQKPPVGAIGIPGAAGTTSEFGAAAGSDAVQ
EEECCCCCCCCCCCCCCCEEEECCCCCEEECCCCCCEEECCCCCCCCHHHCCCCCCCCEE
YSDRSLNINQTAQGILEANDPPVRMLWVACKNPFAQDFDRSKMKKAFEKLEMVVCADQFF
ECCCCCCCCHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NETVQHADIVLPVTTAFEEWNVDASYWHYWLSINQPAIKPMYEAKCDLEIATMLSRTINK
HHHHHHCEEEEEEEHHHHHCCCCHHHEEEEEEECCCCCCCHHHCCCCHHHHHHHHHHHHH
MAPGSCTFPQEFDHKRWLDQEFNDGMAKMFGISSWDDLLDGPKKAILPSSAAWYDRKFKT
CCCCCCCCCHHHCHHHHHHHHHCCCHHHHHCCCCHHHHHCCCCHHCCCCCCHHHCCEECC
PSGKYEFKSELAEKNGHTALPEYKPEAESKLPFHLFTPHVQFGLHSQFINLDWMQVFYPE
CCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCHHCCCHHHEECCCEEEEECCC
PFVYIHPSSAKKKGISENDRVKVFNNIGEVELRAKVTTNVPEDFLVMYEAWFPKRQYNVQ
CEEEECCCCHHHCCCCCCCCEEEECCCCCEEEEEEEECCCCHHHHHHHHHHCCCCCCCHH
NVVADTPADMGLMKTGAPGAAIHSQFADVVLIGKGESVA
HHCCCCCCCCCEEECCCCCHHHHHCCCCEEEEECCCCCC
>Mature Secondary Structure 
SNETGHLNRRSFLKGIVALGTVAALPGGLLTSRCALAQPPVPFNPKTYKIYRNACPRNC
CCCCCCCHHHHHHHHHHHHHHHHHCCCCHHHHHHHCCCCCCCCCCCEEEEEECCCCCCC
YDTCSLKTWVKDGVITFVEGAPESTFTHGTPYVKGLSYPRRVYSPDRIKYPMAQDVRGSG
HHCCCHHHHHHCCCEEEEECCCCCCCCCCCCCCCCCCCCHHHCCCCCCCCCCHHCCCCCC
NWRRISWEEAMQRIAAKMLEIKKKDSSMLGLALTKYSGKFGVLNYAVEGMMSSLGYTTRF
CEEEECHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHHHHHHCCCEEEC
AGTPCWPAGIDAQNYDMGDMWCNDPEDMVKAKYIIIWGANPAWCSMHSMKYIYQAREKGA
CCCCCCCCCCCCCCCCCCCCCCCCHHHHCEEEEEEEECCCCHHHHHHHHHHHHHHHHCCC
KVVVIDPLLSQTAAKADLYLRVRPGSDGALALGMARHLVDKGLVDQDFVNNDAHGYPEFE
EEEEECHHHHHHHCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCHHHCCCCCCCCCHHH
AYLRNHVTVEWAAEICGLSAQVIRQLAEEFTAVNPATAWIGYGMQRHVNGGANVRAIDAF
HHHHHCCEEEEHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHCCHHEECCCCCCEEEEEEE
VAMSGNIGVEGGGARYGHLHTWGFNYNAMLQKPPVGAIGIPGAAGTTSEFGAAAGSDAVQ
EEECCCCCCCCCCCCCCCEEEECCCCCEEECCCCCCEEECCCCCCCCHHHCCCCCCCCEE
YSDRSLNINQTAQGILEANDPPVRMLWVACKNPFAQDFDRSKMKKAFEKLEMVVCADQFF
ECCCCCCCCHHHHHHCCCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
NETVQHADIVLPVTTAFEEWNVDASYWHYWLSINQPAIKPMYEAKCDLEIATMLSRTINK
HHHHHHCEEEEEEEHHHHHCCCCHHHEEEEEEECCCCCCCHHHCCCCHHHHHHHHHHHHH
MAPGSCTFPQEFDHKRWLDQEFNDGMAKMFGISSWDDLLDGPKKAILPSSAAWYDRKFKT
CCCCCCCCCHHHCHHHHHHHHHCCCHHHHHCCCCHHHHHCCCCHHCCCCCCHHHCCEECC
PSGKYEFKSELAEKNGHTALPEYKPEAESKLPFHLFTPHVQFGLHSQFINLDWMQVFYPE
CCCCHHHHHHHHHCCCCCCCCCCCCCCCCCCCEEEECCCHHCCCHHHEECCCEEEEECCC
PFVYIHPSSAKKKGISENDRVKVFNNIGEVELRAKVTTNVPEDFLVMYEAWFPKRQYNVQ
CEEEECCCCHHHCCCCCCCCEEEECCCCCEEEEEEEECCCCHHHHHHHHHHCCCCCCCHH
NVVADTPADMGLMKTGAPGAAIHSQFADVVLIGKGESVA
HHCCCCCCCCCEEECCCCCHHHHHCCCCEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: May Bind 4Fe-4S Cluster. [C]

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7584024; 9384377; 1552862 [H]