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The map label for this gene is lnt

Identifier: 29142609

GI number: 29142609

Start: 2272617

End: 2274155

Strand: Direct

Name: lnt

Synonym: t2207

Alternate gene names: 29142609

Gene position: 2272617-2274155 (Clockwise)

Preceding gene: 29142608

Following gene: 29142610

Centisome position: 47.43

GC content: 55.04

Gene sequence:

>1539_bases
ATGGCATTTGCCTCGTTAATTGAACGCCAGCGTATTCGCCTGCTGCTGGCGTTATTATTCGGCGCCTGCGGAACACTGGC
TTTCTCTCCGTATGACGTCTGGCCCGCAGCGATAGTGTCGCTTATCGGGCTGCAGGCCTTAACGTTTAATCGCCGCCCGC
TCCAGTCTGCCGCCATCGGCTATTGCTGGGGACTCGGACTTTTCGGCAGCGGGATTAACTGGGTTTATGTCAGTATCGCG
CAGTTTGGCGGCATGCCGGGCCCGGTTAACGTTTTTCTGGTGGTGCTGCTTGCAGCTTATCTCTCGCTGTATACCGGACT
GTTTGCCGGGATTTTGTCGCGCCTGTGGCCAAAAACCAACTGGCTGCGCGTCGCTATCGCCGCGCCTGCAATATGGCAAA
TCACCGAATTTTTACGCGGCTGGGTGCTGACCGGCTTCCCCTGGCTGCAATTTGGCTATAGTCAGGTCGACGGCCCGCTA
AAAGGCCTGGCGCCGGTAATGGGCGTCGAAGCGATCAACTTCCTGCTGATGATGGTCAGCGGCCTGTTAGCGCTGGCACT
GGCGACGCGGAACTGGCGTCCGCTGGCTGTCGCCGTGATTCTGTTTGCTTTGCCCTTTCCGCTACGTTATATCCAGTGGT
TTACGCTGGAACCTACCAAAGCGACCCAGGTATCGCTGGTGCAGGGCGATATTCCGCAGTCGCTGAAGTGGGACGAAAAC
CAGCTACTGAATACGCTAAACATTTATCTCAACGAAACTCGCCCAGAGTTAGGCAAATCACAGATTATTATCTGGCCTGA
GTCGGCGATTCCGGATCTCGAAATCAATCAGCAGCCTTTCCTTCGTTCGCTGGACGAGATGTTACGCGAAAAAAATAGCA
CGCTGATCACCGGTATTGTCGATGCGCGTCTCAATAAACAGAATCGATACGACACCTACAATACGATTATTACGTTGGGC
AAGGATAATCCATACAGTTATGACTCGCCCAATCGCTACAATAAAAATCACCTTGTACCCTTTGGCGAGTTCGTTCCGCT
GGAGTCTATCCTGCGTCCGCTGGCGCCGTTCTTCGATCTGCCCATGTCCTCCTTTAGCCGCGGCCCTTATATCCAGCCGC
AGTTACATGCGCACGACTATAAGCTGACGGCGGCAATCTGTTATGAAATTATTCTTGGCGAACAGGTGCGGGATAACTTC
CGCCCGGACACCGACTATCTGCTGACGATTTCTAACGACGCCTGGTTTGGTAAGTCCATTGGCCCGTGGCAACATTTCCA
GATGGCGCGGATGCGTTCGCTGGAGCTGGCGCGTCCGTTGCTGCGCAGTACTAATAACGGTATTACGGCGGTGATTGGCC
CGCAGGGCGAAATTCAGGCGATGATCCCGCAGTTCACACGCCAGGTGCTAACTACCAAAGTCACGCCGACCACCGGCCTG
ACGCCGTACGCACGAACCGGCGACTGGACGGTGTGGTTGATTACCGTACTGTTCGGCTTTGGCGCGCTGGTGATGAGCCT
GCGTCAACGCCGCAAATAA

Upstream 100 bases:

>100_bases
GCAATGGCCGATAGTCGTCGTATTATTCAGGTGCATGTCAGGATCCCGGATGACTCGCCCCAGCCAAAACTGGACGAATA
ACAGCAATAGTGGACTAAAA

Downstream 100 bases:

>100_bases
AACATTGCACTATCCAATGTAGGCCGGATAAGGCGTTACGCCGCCATCCGGCAGTTGTATCGCACCGTGCCTGATGGCGC
TACGCTTATCAGGCCTACAA

Product: apolipoprotein N-acyltransferase

Products: NA

Alternate protein names: ALP N-acyltransferase; Copper homeostasis protein CutE

Number of amino acids: Translated: 512; Mature: 511

Protein sequence:

>512_residues
MAFASLIERQRIRLLLALLFGACGTLAFSPYDVWPAAIVSLIGLQALTFNRRPLQSAAIGYCWGLGLFGSGINWVYVSIA
QFGGMPGPVNVFLVVLLAAYLSLYTGLFAGILSRLWPKTNWLRVAIAAPAIWQITEFLRGWVLTGFPWLQFGYSQVDGPL
KGLAPVMGVEAINFLLMMVSGLLALALATRNWRPLAVAVILFALPFPLRYIQWFTLEPTKATQVSLVQGDIPQSLKWDEN
QLLNTLNIYLNETRPELGKSQIIIWPESAIPDLEINQQPFLRSLDEMLREKNSTLITGIVDARLNKQNRYDTYNTIITLG
KDNPYSYDSPNRYNKNHLVPFGEFVPLESILRPLAPFFDLPMSSFSRGPYIQPQLHAHDYKLTAAICYEIILGEQVRDNF
RPDTDYLLTISNDAWFGKSIGPWQHFQMARMRSLELARPLLRSTNNGITAVIGPQGEIQAMIPQFTRQVLTTKVTPTTGL
TPYARTGDWTVWLITVLFGFGALVMSLRQRRK

Sequences:

>Translated_512_residues
MAFASLIERQRIRLLLALLFGACGTLAFSPYDVWPAAIVSLIGLQALTFNRRPLQSAAIGYCWGLGLFGSGINWVYVSIA
QFGGMPGPVNVFLVVLLAAYLSLYTGLFAGILSRLWPKTNWLRVAIAAPAIWQITEFLRGWVLTGFPWLQFGYSQVDGPL
KGLAPVMGVEAINFLLMMVSGLLALALATRNWRPLAVAVILFALPFPLRYIQWFTLEPTKATQVSLVQGDIPQSLKWDEN
QLLNTLNIYLNETRPELGKSQIIIWPESAIPDLEINQQPFLRSLDEMLREKNSTLITGIVDARLNKQNRYDTYNTIITLG
KDNPYSYDSPNRYNKNHLVPFGEFVPLESILRPLAPFFDLPMSSFSRGPYIQPQLHAHDYKLTAAICYEIILGEQVRDNF
RPDTDYLLTISNDAWFGKSIGPWQHFQMARMRSLELARPLLRSTNNGITAVIGPQGEIQAMIPQFTRQVLTTKVTPTTGL
TPYARTGDWTVWLITVLFGFGALVMSLRQRRK
>Mature_511_residues
AFASLIERQRIRLLLALLFGACGTLAFSPYDVWPAAIVSLIGLQALTFNRRPLQSAAIGYCWGLGLFGSGINWVYVSIAQ
FGGMPGPVNVFLVVLLAAYLSLYTGLFAGILSRLWPKTNWLRVAIAAPAIWQITEFLRGWVLTGFPWLQFGYSQVDGPLK
GLAPVMGVEAINFLLMMVSGLLALALATRNWRPLAVAVILFALPFPLRYIQWFTLEPTKATQVSLVQGDIPQSLKWDENQ
LLNTLNIYLNETRPELGKSQIIIWPESAIPDLEINQQPFLRSLDEMLREKNSTLITGIVDARLNKQNRYDTYNTIITLGK
DNPYSYDSPNRYNKNHLVPFGEFVPLESILRPLAPFFDLPMSSFSRGPYIQPQLHAHDYKLTAAICYEIILGEQVRDNFR
PDTDYLLTISNDAWFGKSIGPWQHFQMARMRSLELARPLLRSTNNGITAVIGPQGEIQAMIPQFTRQVLTTKVTPTTGLT
PYARTGDWTVWLITVLFGFGALVMSLRQRRK

Specific function: Transfers the fatty acyl group on membrane lipoproteins

COG id: COG0815

COG function: function code M; Apolipoprotein N-acyltransferase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 CN hydrolase domain

Homologues:

Organism=Escherichia coli, GI1786878, Length=512, Percent_Identity=87.6953125, Blast_Score=928, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): LNT_SALTI (Q8Z8G7)

Other databases:

- EMBL:   AL627267
- EMBL:   AE014613
- RefSeq:   NP_455235.1
- RefSeq:   NP_805951.1
- ProteinModelPortal:   Q8Z8G7
- GeneID:   1069319
- GeneID:   1247169
- GenomeReviews:   AE014613_GR
- GenomeReviews:   AL513382_GR
- KEGG:   stt:t2207
- KEGG:   sty:STY0711
- HOGENOM:   HBG616234
- OMA:   FESYFPE
- ProtClustDB:   PRK00302
- BioCyc:   SENT209261:T2207-MONOMER
- BioCyc:   SENT220341:STY0711-MONOMER
- HAMAP:   MF_01148
- InterPro:   IPR004563
- InterPro:   IPR003010
- Gene3D:   G3DSA:3.60.110.10
- TIGRFAMs:   TIGR00546

Pfam domain/function: PF00795 CN_hydrolase; SSF56317 Ntlse/CNhydtse

EC number: 2.3.1.- [C]

Molecular weight: Translated: 57662; Mature: 57531

Theoretical pI: Translated: 9.62; Mature: 9.62

Prosite motif: PS50263 CN_HYDROLASE

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xf38d224)-; HASH(0xf1b7ccc)-; HASH(0xf0a3b64)-; HASH(0xf0c62f8)-; HASH(0xdf13d78)-; HASH(0xf7fd6e4)-; HASH(0xf5c0cbc)-; HASH(0xb838e2c)-;

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFASLIERQRIRLLLALLFGACGTLAFSPYDVWPAAIVSLIGLQALTFNRRPLQSAAIG
CCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
YCWGLGLFGSGINWVYVSIAQFGGMPGPVNVFLVVLLAAYLSLYTGLFAGILSRLWPKTN
HHHHHHHHCCCCHHEEEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
WLRVAIAAPAIWQITEFLRGWVLTGFPWLQFGYSQVDGPLKGLAPVMGVEAINFLLMMVS
EEEEEEECCHHHHHHHHHHHHHHCCCHHHHHCHHHCCCCHHHHHHHHHHHHHHHHHHHHH
GLLALALATRNWRPLAVAVILFALPFPLRYIQWFTLEPTKATQVSLVQGDIPQSLKWDEN
HHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHEEEECCCCCCCEEEEEECCCCCCCCCCHH
QLLNTLNIYLNETRPELGKSQIIIWPESAIPDLEINQQPFLRSLDEMLREKNSTLITGIV
HHHHHHHHHEECCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEH
DARLNKQNRYDTYNTIITLGKDNPYSYDSPNRYNKNHLVPFGEFVPLESILRPLAPFFDL
HHHCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
PMSSFSRGPYIQPQLHAHDYKLTAAICYEIILGEQVRDNFRPDTDYLLTISNDAWFGKSI
CHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCC
GPWQHFQMARMRSLELARPLLRSTNNGITAVIGPQGEIQAMIPQFTRQVLTTKVTPTTGL
CCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCC
TPYARTGDWTVWLITVLFGFGALVMSLRQRRK
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCH
>Mature Secondary Structure 
AFASLIERQRIRLLLALLFGACGTLAFSPYDVWPAAIVSLIGLQALTFNRRPLQSAAIG
CHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHH
YCWGLGLFGSGINWVYVSIAQFGGMPGPVNVFLVVLLAAYLSLYTGLFAGILSRLWPKTN
HHHHHHHHCCCCHHEEEEHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
WLRVAIAAPAIWQITEFLRGWVLTGFPWLQFGYSQVDGPLKGLAPVMGVEAINFLLMMVS
EEEEEEECCHHHHHHHHHHHHHHCCCHHHHHCHHHCCCCHHHHHHHHHHHHHHHHHHHHH
GLLALALATRNWRPLAVAVILFALPFPLRYIQWFTLEPTKATQVSLVQGDIPQSLKWDEN
HHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHEEEECCCCCCCEEEEEECCCCCCCCCCHH
QLLNTLNIYLNETRPELGKSQIIIWPESAIPDLEINQQPFLRSLDEMLREKNSTLITGIV
HHHHHHHHHEECCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHHHHCCCEEEEEEH
DARLNKQNRYDTYNTIITLGKDNPYSYDSPNRYNKNHLVPFGEFVPLESILRPLAPFFDL
HHHCCCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCC
PMSSFSRGPYIQPQLHAHDYKLTAAICYEIILGEQVRDNFRPDTDYLLTISNDAWFGKSI
CHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCCCC
GPWQHFQMARMRSLELARPLLRSTNNGITAVIGPQGEIQAMIPQFTRQVLTTKVTPTTGL
CCHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHHHHHHHCCCCCCCC
TPYARTGDWTVWLITVLFGFGALVMSLRQRRK
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Transferases; Acyltransferases; Transferring groups other than amino-acyl groups [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504