Definition Salmonella enterica subsp. enterica serovar Typhi str. Ty2 chromosome, complete genome.
Accession NC_004631
Length 4,791,961

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The map label for this gene is fecD [C]

Identifier: 29142532

GI number: 29142532

Start: 2180997

End: 2182076

Strand: Reverse

Name: fecD [C]

Synonym: t2117

Alternate gene names: 29142532

Gene position: 2182076-2180997 (Counterclockwise)

Preceding gene: 29142533

Following gene: 29142531

Centisome position: 45.54

GC content: 55.93

Gene sequence:

>1080_bases
ATGACCTGTCAGGACAAATCACTTTTAGCCCCCGGTCTCGCTTCCACGCCCGTCATTCCGCGCTATCGCCAGATCATACG
CAAACGGGCCGTGCTCATGTCAGCTATTGCGCTGGCGATGATGGTTTCACTGATGGTGGATGTAACCTGTGGGTCTTCTG
GTTTACCGCTCAGTGCGCTGTGGCAGGCGCTTTTCCAGCCGGAAAAGGTGAATGCGGGCATACACGTTATTGTCTGGGAT
ATCCGCTTACCCTATGCCCTGATGGCCCTACTGGTGGGCATGGCGTTAGGGTTAGCGGGCGCCGAAATGCAAACCATTTT
AAATAATCCGCTGGCGACGCCGTTTACCCTTGGCGTATCGTCCGCGGCGGCTTTTGGCGCTGCGCTGGCGATTGTGTTGG
GGATCGGTATTCCCGGTATTCCTGCCGCCTGGTTTATCCCGGCCAATGCGTTCATCTTTGCGCTTTTATCCGCGTTACTC
CTGGACGGTATTACCCGTTGGACAGGCGTCGCCGCATCCGGAGTGGTGTTGTTCGGTATTGCGCTGGTATTCACCTTTAA
CGCGTTGGTCGCCATTATGCAGTTTGTGGCTGATGAAGATACGCTGCAGGGGCTGGTATTCTGGACGATGGGGAGCCTGG
TCCGCGCGTCGTGGGAAAAATTGGGCGTACTGGCCGTGGTGTTTATTGCTGTGCTTTTTTGCGCGTTACGAAGCGCCTGG
CAACTCACGGCATTACGTCTGGGCGAAGAGAGGGCGATGAGCTTTGGGGTTCATGTCCGCCGTTTACGCCTGCTGTCATT
GTTGCGTATCAGCTTGTTATCAGCGCTGGCGGTAGCTTTCGTCGGGCCGATTGGTTTTATTGGTCTCGTTGCGCCGCACA
TTGCGCGAATACTGTTGGGGGAAGATCACCGTTTCTACCTTCCGGGCAGCGTGCTGATAGGCGGGCTGGTGTTATCGCTG
GCCTCTATTGCGGCGAAAAATAGTATTCCGGGCGTCATGGTGCCGGTGGGGATTGTCACCTCGCTGGTCGGGGTTCCGTT
CTTTTTAAGCATTGTATTGCGACATCGGGGGAGTCTCTGA

Upstream 100 bases:

>100_bases
ATGAGATAGCCCACCGTGTCATCAATCGAAATATAAATAAATATATAACGAAATAATTCGGCGCTATAATTCTCTTCTGA
TTAATAACGTCGCTCGAACC

Downstream 100 bases:

>100_bases
TGCGCAGGTTAATGCTCCGCTCATTTAGCGCCGGCTATTCCACTCAGCCGGTTATTGCAGATCTCAACGTTCCCTTACTG
CCGCGCGGGAAAATTACCAT

Product: ABC transporter permease

Products: ADP; phosphate; iron dicitrate [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 359; Mature: 358

Protein sequence:

>359_residues
MTCQDKSLLAPGLASTPVIPRYRQIIRKRAVLMSAIALAMMVSLMVDVTCGSSGLPLSALWQALFQPEKVNAGIHVIVWD
IRLPYALMALLVGMALGLAGAEMQTILNNPLATPFTLGVSSAAAFGAALAIVLGIGIPGIPAAWFIPANAFIFALLSALL
LDGITRWTGVAASGVVLFGIALVFTFNALVAIMQFVADEDTLQGLVFWTMGSLVRASWEKLGVLAVVFIAVLFCALRSAW
QLTALRLGEERAMSFGVHVRRLRLLSLLRISLLSALAVAFVGPIGFIGLVAPHIARILLGEDHRFYLPGSVLIGGLVLSL
ASIAAKNSIPGVMVPVGIVTSLVGVPFFLSIVLRHRGSL

Sequences:

>Translated_359_residues
MTCQDKSLLAPGLASTPVIPRYRQIIRKRAVLMSAIALAMMVSLMVDVTCGSSGLPLSALWQALFQPEKVNAGIHVIVWD
IRLPYALMALLVGMALGLAGAEMQTILNNPLATPFTLGVSSAAAFGAALAIVLGIGIPGIPAAWFIPANAFIFALLSALL
LDGITRWTGVAASGVVLFGIALVFTFNALVAIMQFVADEDTLQGLVFWTMGSLVRASWEKLGVLAVVFIAVLFCALRSAW
QLTALRLGEERAMSFGVHVRRLRLLSLLRISLLSALAVAFVGPIGFIGLVAPHIARILLGEDHRFYLPGSVLIGGLVLSL
ASIAAKNSIPGVMVPVGIVTSLVGVPFFLSIVLRHRGSL
>Mature_358_residues
TCQDKSLLAPGLASTPVIPRYRQIIRKRAVLMSAIALAMMVSLMVDVTCGSSGLPLSALWQALFQPEKVNAGIHVIVWDI
RLPYALMALLVGMALGLAGAEMQTILNNPLATPFTLGVSSAAAFGAALAIVLGIGIPGIPAAWFIPANAFIFALLSALLL
DGITRWTGVAASGVVLFGIALVFTFNALVAIMQFVADEDTLQGLVFWTMGSLVRASWEKLGVLAVVFIAVLFCALRSAWQ
LTALRLGEERAMSFGVHVRRLRLLSLLRISLLSALAVAFVGPIGFIGLVAPHIARILLGEDHRFYLPGSVLIGGLVLSLA
SIAAKNSIPGVMVPVGIVTSLVGVPFFLSIVLRHRGSL

Specific function: Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790740, Length=325, Percent_Identity=32, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI1786805, Length=314, Percent_Identity=37.8980891719745, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1788004, Length=281, Percent_Identity=34.5195729537367, Blast_Score=116, Evalue=2e-27,
Organism=Escherichia coli, GI1790741, Length=286, Percent_Identity=36.013986013986, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1786347, Length=278, Percent_Identity=31.294964028777, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI1786804, Length=285, Percent_Identity=32.6315789473684, Blast_Score=88, Evalue=7e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 37941; Mature: 37810

Theoretical pI: Translated: 10.73; Mature: 10.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTCQDKSLLAPGLASTPVIPRYRQIIRKRAVLMSAIALAMMVSLMVDVTCGSSGLPLSAL
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
WQALFQPEKVNAGIHVIVWDIRLPYALMALLVGMALGLAGAEMQTILNNPLATPFTLGVS
HHHHCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHCHH
SAAAFGAALAIVLGIGIPGIPAAWFIPANAFIFALLSALLLDGITRWTGVAASGVVLFGI
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALVFTFNALVAIMQFVADEDTLQGLVFWTMGSLVRASWEKLGVLAVVFIAVLFCALRSAW
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLTALRLGEERAMSFGVHVRRLRLLSLLRISLLSALAVAFVGPIGFIGLVAPHIARILLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
EDHRFYLPGSVLIGGLVLSLASIAAKNSIPGVMVPVGIVTSLVGVPFFLSIVLRHRGSL
CCCCEECCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TCQDKSLLAPGLASTPVIPRYRQIIRKRAVLMSAIALAMMVSLMVDVTCGSSGLPLSAL
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHH
WQALFQPEKVNAGIHVIVWDIRLPYALMALLVGMALGLAGAEMQTILNNPLATPFTLGVS
HHHHCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCHHHCHH
SAAAFGAALAIVLGIGIPGIPAAWFIPANAFIFALLSALLLDGITRWTGVAASGVVLFGI
HHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALVFTFNALVAIMQFVADEDTLQGLVFWTMGSLVRASWEKLGVLAVVFIAVLFCALRSAW
HHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLTALRLGEERAMSFGVHVRRLRLLSLLRISLLSALAVAFVGPIGFIGLVAPHIARILLG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
EDHRFYLPGSVLIGGLVLSLASIAAKNSIPGVMVPVGIVTSLVGVPFFLSIVLRHRGSL
CCCCEECCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; iron dicitrate [Periplasm]; H2O [C]

Specific reaction: ATP + iron dicitrate [Periplasm] + H2O = ADP + phosphate + iron dicitrate [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]