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The map label for this gene is exo [H]

Identifier: 29142349

GI number: 29142349

Start: 1967759

End: 1968439

Strand: Direct

Name: exo [H]

Synonym: t1924

Alternate gene names: 29142349

Gene position: 1967759-1968439 (Clockwise)

Preceding gene: 29142348

Following gene: 29142350

Centisome position: 41.06

GC content: 53.01

Gene sequence:

>681_bases
ATGACACCAGAAATTATCCTGGCTCGTACAGGTATTGACGTTAGCAACATCGAGCAAGGTGATGACGCGTGGCACCGTCT
ACGCCTCGGTGTCATCACTGCTTCCGAAGTTCACAACGTCATTTCCAGGCCAAAGTCGGGCAAGAAGTGGACTGATATGA
AGATGTCCTACTTTCTCACCCTTCTTGCCGAAGTTTGCACCGGCGTGGCACCGGAAGTTAACGCCAGGGCGCTGGCCTGG
GGGAAACAGTATGAAGATGATGCCCGCACCCTGTTTGAGTTCACCACTGACGTGAAAGTCACCGGGTCGCCGATCCTTTT
CCGTGACGAGGACATGCGTACCGCCTGTTCTCCTGACGGCCTGTGCAGTGATGGCCGCGGTCTTGAGTTGAAATGCCCTT
TCACCTCTCGCGACTTTATGAAATTCAGGCTTGGCGGCTTCGAGGCTATCAAATCCGCCTATATGGCCCAGGTGCAATTC
AGCATGTGGGTAACCGGGATAGATGCCTGGTATTTCGCGAATTATGACCCGCGCATGAAGCGAGAAGGCATTCACCACGT
GGTTGTTGAGCGCGACGACAAATACATGTCCCTCTTCAATGAAATGGTACCGGAATTTATCGAAAAGATGGACGAAGCGC
TAAAGGAGATTGGCTTCACGTTCGGGGAGCAGTGGCGATGA

Upstream 100 bases:

>100_bases
TCCGTCGCGATATTGGTGCATCGTCAGATCTTACGCAAATCGAAGCAGTGAAAGCCCTCGGATTCCTGAAGCAGAAAGCA
GCAGAACAGAAGGTGGAAGC

Downstream 100 bases:

>100_bases
CGCACGCACAGGACGAAATCAGGGTTGGCGCGATGCGCCATCCCATGTTGAAGAATTAAATGTTAGAGGACGGAAGTATG
AGCAAAATTGGTGACTATTT

Product: exonuclease

Products: H2O; 2-oxopent-4-enoate [C]

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MTPEIILARTGIDVSNIEQGDDAWHRLRLGVITASEVHNVISRPKSGKKWTDMKMSYFLTLLAEVCTGVAPEVNARALAW
GKQYEDDARTLFEFTTDVKVTGSPILFRDEDMRTACSPDGLCSDGRGLELKCPFTSRDFMKFRLGGFEAIKSAYMAQVQF
SMWVTGIDAWYFANYDPRMKREGIHHVVVERDDKYMSLFNEMVPEFIEKMDEALKEIGFTFGEQWR

Sequences:

>Translated_226_residues
MTPEIILARTGIDVSNIEQGDDAWHRLRLGVITASEVHNVISRPKSGKKWTDMKMSYFLTLLAEVCTGVAPEVNARALAW
GKQYEDDARTLFEFTTDVKVTGSPILFRDEDMRTACSPDGLCSDGRGLELKCPFTSRDFMKFRLGGFEAIKSAYMAQVQF
SMWVTGIDAWYFANYDPRMKREGIHHVVVERDDKYMSLFNEMVPEFIEKMDEALKEIGFTFGEQWR
>Mature_225_residues
TPEIILARTGIDVSNIEQGDDAWHRLRLGVITASEVHNVISRPKSGKKWTDMKMSYFLTLLAEVCTGVAPEVNARALAWG
KQYEDDARTLFEFTTDVKVTGSPILFRDEDMRTACSPDGLCSDGRGLELKCPFTSRDFMKFRLGGFEAIKSAYMAQVQFS
MWVTGIDAWYFANYDPRMKREGIHHVVVERDDKYMSLFNEMVPEFIEKMDEALKEIGFTFGEQWR

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: To Bacteriophage lambda exonuclease exo [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011604
- InterPro:   IPR011335 [H]

Pfam domain/function: NA

EC number: 3.1.11.3 [C]

Molecular weight: Translated: 25910; Mature: 25779

Theoretical pI: Translated: 5.03; Mature: 5.03

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.6 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPEIILARTGIDVSNIEQGDDAWHRLRLGVITASEVHNVISRPKSGKKWTDMKMSYFLT
CCCCEEEEECCCCHHCCCCCCHHHHHHHHHEEEHHHHHHHHHCCCCCCCHHHHHHHHHHH
LLAEVCTGVAPEVNARALAWGKQYEDDARTLFEFTTDVKVTGSPILFRDEDMRTACSPDG
HHHHHHCCCCCCCCCHHHHCCCCCCHHHHHHHHHHCCEEECCCEEEEECCCCCCCCCCCC
LCSDGRGLELKCPFTSRDFMKFRLGGFEAIKSAYMAQVQFSMWVTGIDAWYFANYDPRMK
CCCCCCCCEEECCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHEEECCEEEECCCCCHHH
REGIHHVVVERDDKYMSLFNEMVPEFIEKMDEALKEIGFTFGEQWR
HCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TPEIILARTGIDVSNIEQGDDAWHRLRLGVITASEVHNVISRPKSGKKWTDMKMSYFLT
CCCEEEEECCCCHHCCCCCCHHHHHHHHHEEEHHHHHHHHHCCCCCCCHHHHHHHHHHH
LLAEVCTGVAPEVNARALAWGKQYEDDARTLFEFTTDVKVTGSPILFRDEDMRTACSPDG
HHHHHHCCCCCCCCCHHHHCCCCCCHHHHHHHHHHCCEEECCCEEEEECCCCCCCCCCCC
LCSDGRGLELKCPFTSRDFMKFRLGGFEAIKSAYMAQVQFSMWVTGIDAWYFANYDPRMK
CCCCCCCCEEECCCCCCHHHHHHHCHHHHHHHHHHHHHHHHHHEEECCEEEECCCCCHHH
REGIHHVVVERDDKYMSLFNEMVPEFIEKMDEALKEIGFTFGEQWR
HCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: 4-hydroxy-2-ketovalerate [C]

Specific reaction: 4-hydroxy-2-ketovalerate = H2O + 2-oxopent-4-enoate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]