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The map label for this gene is yciA

Identifier: 29142084

GI number: 29142084

Start: 1706274

End: 1706675

Strand: Direct

Name: yciA

Synonym: t1648

Alternate gene names: 29142084

Gene position: 1706274-1706675 (Clockwise)

Preceding gene: 29142083

Following gene: 29142086

Centisome position: 35.61

GC content: 54.23

Gene sequence:

>402_bases
ATGACAACAATGGATAATACTCCTCAGGGCGAGCTGGTTTTACGTACATTGGCCATGCCTGCCGATACCAATGCGAACGG
CGATATTTTTGGCGGCTGGCTGATGTCGCAAATGGATATTGGCGGCGCGATACTGGCCAAAGAGATCGCGCACGGTCGGG
TTGTAACCGTACGCGTGGAAGGAATGACATTTCTGCGCCCCGTCGCGGTTGGCGATGTCGTATGCTGCTACGCGCGCTGC
GTTAAACGCGGTACGACGTCTATTAGCATCAATATTGAAGTCTGGGTGAAAAAAGTCGCGTCAGAACCGATTGGACAGCG
CTACAAGGCCACCGAGGCGCTGTTTATTTATGTTGCCGTCGATCCGGACGGTAAACCTCGCCCGCTCCCGGTTCAGGGTT
AA

Upstream 100 bases:

>100_bases
CGCCCTGCGCTTTCCCGTCAGTACCTTTATTCCCACTATTCTCCACACAATATTCATAGTAGCATCGCGGCTGTAATTTT
TTCTGATAGTCGGTTTTACA

Downstream 100 bases:

>100_bases
GTATACCCGCTTACGCCGCCAGCAGGTGATGGTATATTCCTACTGGCGGCGCCAGAGATTACTCAATCTGCGCCGCACCG
TTCAGACGGAAGATAATATT

Product: acyl-CoA thioester hydrolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 133; Mature: 132

Protein sequence:

>133_residues
MTTMDNTPQGELVLRTLAMPADTNANGDIFGGWLMSQMDIGGAILAKEIAHGRVVTVRVEGMTFLRPVAVGDVVCCYARC
VKRGTTSISINIEVWVKKVASEPIGQRYKATEALFIYVAVDPDGKPRPLPVQG

Sequences:

>Translated_133_residues
MTTMDNTPQGELVLRTLAMPADTNANGDIFGGWLMSQMDIGGAILAKEIAHGRVVTVRVEGMTFLRPVAVGDVVCCYARC
VKRGTTSISINIEVWVKKVASEPIGQRYKATEALFIYVAVDPDGKPRPLPVQG
>Mature_132_residues
TTMDNTPQGELVLRTLAMPADTNANGDIFGGWLMSQMDIGGAILAKEIAHGRVVTVRVEGMTFLRPVAVGDVVCCYARCV
KRGTTSISINIEVWVKKVASEPIGQRYKATEALFIYVAVDPDGKPRPLPVQG

Specific function: Catalyzes the hydrolysis of the thioester bond in palmitoyl-CoA and malonyl-CoA

COG id: COG1607

COG function: function code I; Acyl-CoA hydrolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the acyl coenzyme A hydrolase family

Homologues:

Organism=Escherichia coli, GI1787506, Length=132, Percent_Identity=90.9090909090909, Blast_Score=252, Evalue=6e-69,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): YCIA_SALTI (P0A1A2)

Other databases:

- EMBL:   AL627269
- EMBL:   AE014613
- RefSeq:   NP_455762.1
- RefSeq:   NP_805426.1
- ProteinModelPortal:   P0A1A2
- SMR:   P0A1A2
- GeneID:   1071261
- GeneID:   1247715
- GenomeReviews:   AE014613_GR
- GenomeReviews:   AL513382_GR
- KEGG:   stt:t1648
- KEGG:   sty:STY1315
- HOGENOM:   HBG499693
- OMA:   MSQMDMG
- ProtClustDB:   PRK10694
- BioCyc:   SENT209261:T1648-MONOMER
- BioCyc:   SENT220341:STY1315-MONOMER
- InterPro:   IPR006683

Pfam domain/function: PF03061 4HBT

EC number: 3.1.2.- [C]

Molecular weight: Translated: 14364; Mature: 14233

Theoretical pI: Translated: 8.04; Mature: 8.04

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.3 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
6.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTMDNTPQGELVLRTLAMPADTNANGDIFGGWLMSQMDIGGAILAKEIAHGRVVTVRVE
CCCCCCCCCCCEEEEEECCCCCCCCCCCEEHHEEHHHHCCCHHHHHHHHCCCCEEEEEEC
GMTFLRPVAVGDVVCCYARCVKRGTTSISINIEVWVKKVASEPIGQRYKATEALFIYVAV
CEEEECHHHHHHHHHHHHHHHHCCCCEEEEEHHHEEEHHHCCCCCCCCCCCEEEEEEEEE
DPDGKPRPLPVQG
CCCCCCCCCCCCC
>Mature Secondary Structure 
TTMDNTPQGELVLRTLAMPADTNANGDIFGGWLMSQMDIGGAILAKEIAHGRVVTVRVE
CCCCCCCCCCEEEEEECCCCCCCCCCCEEHHEEHHHHCCCHHHHHHHHCCCCEEEEEEC
GMTFLRPVAVGDVVCCYARCVKRGTTSISINIEVWVKKVASEPIGQRYKATEALFIYVAV
CEEEECHHHHHHHHHHHHHHHHCCCCEEEEEHHHEEEHHHCCCCCCCCCCCEEEEEEEEE
DPDGKPRPLPVQG
CCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on ester bonds; Thiolester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504