BacMap

Definition	Salmonella enterica subsp. enterica serovar Typhi str. Ty2 chromosome, complete genome.
Accession	NC_004631
Length	4,791,961

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The map label for this gene is yciK [H]

Identifier: 29142066

GI number: 29142066

Start: 1689844

End: 1690605

Strand: Direct

Name: yciK [H]

Synonym: t1630

Alternate gene names: 29142066

Gene position: 1689844-1690605 (Clockwise)

Preceding gene: 29142064

Following gene: 29142067

Centisome position: 35.26

GC content: 56.69

Gene sequence:

>762_bases
ATGCATTACCAACCGAAACAAGATCTATTGCAAAACCGCATTATTCTGGTCACTGGTGCCAGCGATGGCATTGGGCGGGA
AGCCGCGCTCACGTATGCGCGTTACGGCGCAACGGTGATTCTGCTGGGACGCAACGAAGAGAAACTGCGTCGGGTCGCGC
AGCACATTGCTGACGAGCAACATGTTCAACCACAGTGGTTTACGCTCGATCTGCTGACCTGCACCGCTGAAGAGTGCCGG
CAAGTGGCCGACCGCATCGCCGCGCACTATCCCCGCCTGGATGGCGTCCTGCACAATGCCGGGTTACTGGGGGAAATCGG
CCCAATGAGCGAACAAGATCCGCAGATCTGGCAGGATGTCATGCAGGTAAACGTTAACGCCACCTTTATGCTCACCCAGG
CGCTGTTACCGTTATTATTGAAGTCCGATGCCGGCTCGCTGGTCTTTACGTCATCAAGCGTTGGCCGTCAGGGACGCGCC
AACTGGGGCGCCTATGCCACCTCGAAGTTTGCTACTGAAGGAATGATGCAGGTGCTGGCGGACGAATACCAGAACCGTTC
TCTGCGTGTTAACTGCATTAACCCGGGCGGCACGCGCACCAGTATGCGCGCCAGCGCCTTTCCGACGGAAGATCCACAGA
AATTAAAAACGCCTGCCGATATTATGCCGCTTTACCTGTGGCTTATGGGCGACGACAGTCGCCGTAAAACCGGTATGACC
TTTGACGCCCAACCGGGCCGTAAACCAGGAATCGCCCAATGA

Upstream 100 bases:

>100_bases
CTGATTGAAAAAAAAGGCGCTTTCAGGCATAAACCCGAAAAGTTAACGCGAAGATAAGACAACCTGGCAGGACGGTGCAC
CACACCGTTGAGGAGTAGCC

Downstream 100 bases:

>100_bases
GTGATGAACGTTATCAGCAGCGCCAGCAGAAGGTAAAAGATCGGGTTGACGCCCGTGTCGCCCAGGCACAGGAAGAGCGC
GGTATTATTATCGTGTTTAC

Product: short chain dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 253; Mature: 253

Protein sequence:

>253_residues
MHYQPKQDLLQNRIILVTGASDGIGREAALTYARYGATVILLGRNEEKLRRVAQHIADEQHVQPQWFTLDLLTCTAEECR
QVADRIAAHYPRLDGVLHNAGLLGEIGPMSEQDPQIWQDVMQVNVNATFMLTQALLPLLLKSDAGSLVFTSSSVGRQGRA
NWGAYATSKFATEGMMQVLADEYQNRSLRVNCINPGGTRTSMRASAFPTEDPQKLKTPADIMPLYLWLMGDDSRRKTGMT
FDAQPGRKPGIAQ

Sequences:

>Translated_253_residues
MHYQPKQDLLQNRIILVTGASDGIGREAALTYARYGATVILLGRNEEKLRRVAQHIADEQHVQPQWFTLDLLTCTAEECR
QVADRIAAHYPRLDGVLHNAGLLGEIGPMSEQDPQIWQDVMQVNVNATFMLTQALLPLLLKSDAGSLVFTSSSVGRQGRA
NWGAYATSKFATEGMMQVLADEYQNRSLRVNCINPGGTRTSMRASAFPTEDPQKLKTPADIMPLYLWLMGDDSRRKTGMT
FDAQPGRKPGIAQ
>Mature_253_residues
MHYQPKQDLLQNRIILVTGASDGIGREAALTYARYGATVILLGRNEEKLRRVAQHIADEQHVQPQWFTLDLLTCTAEECR
QVADRIAAHYPRLDGVLHNAGLLGEIGPMSEQDPQIWQDVMQVNVNATFMLTQALLPLLLKSDAGSLVFTSSSVGRQGRA
NWGAYATSKFATEGMMQVLADEYQNRSLRVNCINPGGTRTSMRASAFPTEDPQKLKTPADIMPLYLWLMGDDSRRKTGMT
FDAQPGRKPGIAQ

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI20149619, Length=206, Percent_Identity=30.5825242718447, Blast_Score=89, Evalue=3e-18,
Organism=Homo sapiens, GI32483357, Length=249, Percent_Identity=26.9076305220884, Blast_Score=87, Evalue=1e-17,
Organism=Homo sapiens, GI5031737, Length=198, Percent_Identity=28.2828282828283, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI33667109, Length=198, Percent_Identity=28.2828282828283, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI142976729, Length=210, Percent_Identity=28.5714285714286, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI4504505, Length=250, Percent_Identity=27.2, Blast_Score=82, Evalue=6e-16,
Organism=Homo sapiens, GI32455239, Length=205, Percent_Identity=31.219512195122, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI5031765, Length=205, Percent_Identity=31.219512195122, Blast_Score=80, Evalue=1e-15,
Organism=Homo sapiens, GI66933014, Length=246, Percent_Identity=28.4552845528455, Blast_Score=78, Evalue=9e-15,
Organism=Homo sapiens, GI157739938, Length=197, Percent_Identity=26.3959390862944, Blast_Score=77, Evalue=2e-14,
Organism=Homo sapiens, GI226371731, Length=214, Percent_Identity=28.5046728971963, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI40807363, Length=203, Percent_Identity=26.1083743842365, Blast_Score=74, Evalue=9e-14,
Organism=Homo sapiens, GI15277342, Length=261, Percent_Identity=27.9693486590038, Blast_Score=74, Evalue=1e-13,
Organism=Homo sapiens, GI126723191, Length=192, Percent_Identity=27.0833333333333, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI7657478, Length=224, Percent_Identity=28.125, Blast_Score=71, Evalue=7e-13,
Organism=Homo sapiens, GI4503817, Length=199, Percent_Identity=26.6331658291457, Blast_Score=71, Evalue=9e-13,
Organism=Homo sapiens, GI210032110, Length=186, Percent_Identity=26.3440860215054, Blast_Score=69, Evalue=6e-12,
Organism=Homo sapiens, GI7705855, Length=207, Percent_Identity=25.1207729468599, Blast_Score=68, Evalue=9e-12,
Organism=Homo sapiens, GI25282469, Length=203, Percent_Identity=26.6009852216749, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI7705925, Length=251, Percent_Identity=26.2948207171315, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI40548397, Length=206, Percent_Identity=27.1844660194175, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI214010158, Length=206, Percent_Identity=27.1844660194175, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI214010156, Length=206, Percent_Identity=27.1844660194175, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI22758144, Length=206, Percent_Identity=27.1844660194175, Blast_Score=67, Evalue=2e-11,
Organism=Homo sapiens, GI126723750, Length=254, Percent_Identity=25.1968503937008, Blast_Score=65, Evalue=7e-11,
Organism=Escherichia coli, GI1787526, Length=253, Percent_Identity=88.9328063241107, Blast_Score=458, Evalue=1e-130,
Organism=Escherichia coli, GI1787335, Length=245, Percent_Identity=28.5714285714286, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI87082100, Length=257, Percent_Identity=30.7392996108949, Blast_Score=84, Evalue=1e-17,
Organism=Escherichia coli, GI1789378, Length=240, Percent_Identity=30.4166666666667, Blast_Score=76, Evalue=2e-15,
Organism=Escherichia coli, GI1786701, Length=212, Percent_Identity=29.2452830188679, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1786812, Length=207, Percent_Identity=26.0869565217391, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI1787905, Length=230, Percent_Identity=28.2608695652174, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790717, Length=193, Percent_Identity=26.9430051813472, Blast_Score=68, Evalue=5e-13,
Organism=Escherichia coli, GI1789208, Length=190, Percent_Identity=24.7368421052632, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI2367175, Length=248, Percent_Identity=26.6129032258064, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1787820, Length=224, Percent_Identity=23.6607142857143, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788459, Length=239, Percent_Identity=22.5941422594142, Blast_Score=63, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71994600, Length=249, Percent_Identity=27.710843373494, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71994604, Length=189, Percent_Identity=31.2169312169312, Blast_Score=88, Evalue=5e-18,
Organism=Caenorhabditis elegans, GI17562908, Length=200, Percent_Identity=33, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI71997402, Length=254, Percent_Identity=28.740157480315, Blast_Score=86, Evalue=2e-17,
Organism=Caenorhabditis elegans, GI17562906, Length=234, Percent_Identity=28.2051282051282, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17544670, Length=203, Percent_Identity=29.5566502463054, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17562904, Length=213, Percent_Identity=27.2300469483568, Blast_Score=82, Evalue=4e-16,
Organism=Caenorhabditis elegans, GI115534694, Length=247, Percent_Identity=27.9352226720648, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17561402, Length=242, Percent_Identity=23.1404958677686, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17560150, Length=211, Percent_Identity=27.9620853080569, Blast_Score=81, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17551412, Length=221, Percent_Identity=28.5067873303167, Blast_Score=80, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17570069, Length=204, Percent_Identity=27.9411764705882, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17560220, Length=205, Percent_Identity=27.8048780487805, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17560676, Length=258, Percent_Identity=24.8062015503876, Blast_Score=79, Evalue=2e-15,
Organism=Caenorhabditis elegans, GI17555706, Length=255, Percent_Identity=25.8823529411765, Blast_Score=77, Evalue=6e-15,
Organism=Caenorhabditis elegans, GI17531453, Length=200, Percent_Identity=29, Blast_Score=77, Evalue=7e-15,
Organism=Caenorhabditis elegans, GI193203117, Length=209, Percent_Identity=26.7942583732057, Blast_Score=75, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI193203115, Length=209, Percent_Identity=26.7942583732057, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17508895, Length=212, Percent_Identity=26.8867924528302, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17567345, Length=200, Percent_Identity=27, Blast_Score=74, Evalue=5e-14,
Organism=Caenorhabditis elegans, GI17568967, Length=244, Percent_Identity=26.2295081967213, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17562990, Length=189, Percent_Identity=28.042328042328, Blast_Score=71, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI193204405, Length=212, Percent_Identity=26.8867924528302, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17560176, Length=193, Percent_Identity=27.4611398963731, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI115534660, Length=240, Percent_Identity=27.0833333333333, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562910, Length=214, Percent_Identity=25.2336448598131, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17538480, Length=215, Percent_Identity=24.1860465116279, Blast_Score=67, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17538182, Length=215, Percent_Identity=29.3023255813954, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI25147288, Length=249, Percent_Identity=24.4979919678715, Blast_Score=67, Evalue=7e-12,
Organism=Caenorhabditis elegans, GI17559104, Length=212, Percent_Identity=26.4150943396226, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17563726, Length=204, Percent_Identity=25, Blast_Score=65, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI72000259, Length=202, Percent_Identity=24.7524752475248, Blast_Score=65, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6323882, Length=229, Percent_Identity=30.5676855895196, Blast_Score=87, Evalue=3e-18,
Organism=Saccharomyces cerevisiae, GI6322227, Length=219, Percent_Identity=29.6803652968037, Blast_Score=80, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6322861, Length=235, Percent_Identity=25.1063829787234, Blast_Score=73, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6322226, Length=195, Percent_Identity=26.1538461538462, Blast_Score=72, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6319635, Length=212, Percent_Identity=25.9433962264151, Blast_Score=62, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24644339, Length=249, Percent_Identity=29.3172690763052, Blast_Score=105, Evalue=2e-23,
Organism=Drosophila melanogaster, GI28571526, Length=253, Percent_Identity=29.2490118577075, Blast_Score=101, Evalue=4e-22,
Organism=Drosophila melanogaster, GI23397609, Length=193, Percent_Identity=32.1243523316062, Blast_Score=98, Evalue=4e-21,
Organism=Drosophila melanogaster, GI21355319, Length=247, Percent_Identity=26.3157894736842, Blast_Score=98, Evalue=6e-21,
Organism=Drosophila melanogaster, GI24643142, Length=205, Percent_Identity=35.609756097561, Blast_Score=95, Evalue=5e-20,
Organism=Drosophila melanogaster, GI21358495, Length=208, Percent_Identity=29.3269230769231, Blast_Score=90, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21357041, Length=252, Percent_Identity=26.5873015873016, Blast_Score=87, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24640492, Length=183, Percent_Identity=27.8688524590164, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24584748, Length=191, Percent_Identity=29.3193717277487, Blast_Score=81, Evalue=6e-16,
Organism=Drosophila melanogaster, GI161076933, Length=191, Percent_Identity=29.3193717277487, Blast_Score=81, Evalue=7e-16,
Organism=Drosophila melanogaster, GI24639444, Length=254, Percent_Identity=27.9527559055118, Blast_Score=80, Evalue=2e-15,
Organism=Drosophila melanogaster, GI28574402, Length=194, Percent_Identity=30.9278350515464, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24584744, Length=194, Percent_Identity=30.9278350515464, Blast_Score=79, Evalue=2e-15,
Organism=Drosophila melanogaster, GI281364892, Length=191, Percent_Identity=29.8429319371728, Blast_Score=79, Evalue=3e-15,
Organism=Drosophila melanogaster, GI45553409, Length=217, Percent_Identity=27.6497695852535, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24647948, Length=217, Percent_Identity=27.6497695852535, Blast_Score=73, Evalue=2e-13,
Organism=Drosophila melanogaster, GI24647946, Length=217, Percent_Identity=27.6497695852535, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI18859837, Length=223, Percent_Identity=28.6995515695067, Blast_Score=70, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24584752, Length=228, Percent_Identity=27.1929824561404, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 28073; Mature: 28073

Theoretical pI: Translated: 7.56; Mature: 7.56

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
4.0 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHYQPKQDLLQNRIILVTGASDGIGREAALTYARYGATVILLGRNEEKLRRVAQHIADEQ
CCCCCHHHHHHCCEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHH
HVQPQWFTLDLLTCTAEECRQVADRIAAHYPRLDGVLHNAGLLGEIGPMSEQDPQIWQDV
CCCCCEEEEEHHHHCHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHH
MQVNVNATFMLTQALLPLLLKSDAGSLVFTSSSVGRQGRANWGAYATSKFATEGMMQVLA
HHHCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
DEYQNRSLRVNCINPGGTRTSMRASAFPTEDPQKLKTPADIMPLYLWLMGDDSRRKTGMT
HHHCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHCCCHHHHEEEEEEECCCCCCCCCCE
FDAQPGRKPGIAQ
ECCCCCCCCCCCC
>Mature Secondary Structure
MHYQPKQDLLQNRIILVTGASDGIGREAALTYARYGATVILLGRNEEKLRRVAQHIADEQ
CCCCCHHHHHHCCEEEEECCCCCCCHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHH
HVQPQWFTLDLLTCTAEECRQVADRIAAHYPRLDGVLHNAGLLGEIGPMSEQDPQIWQDV
CCCCCEEEEEHHHHCHHHHHHHHHHHHHHCCHHHHHHHCCCCCCCCCCCCCCCHHHHHHH
MQVNVNATFMLTQALLPLLLKSDAGSLVFTSSSVGRQGRANWGAYATSKFATEGMMQVLA
HHHCCCHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHH
DEYQNRSLRVNCINPGGTRTSMRASAFPTEDPQKLKTPADIMPLYLWLMGDDSRRKTGMT
HHHCCCCEEEEEECCCCCCCCCCCCCCCCCCHHHHCCCHHHHEEEEEEECCCCCCCCCCE
FDAQPGRKPGIAQ
ECCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Oxidoreductases; Acting on the CH-OH group of donors; With NAD or NADP as acceptor [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 1885549 [H]