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The map label for this gene is ydhC [H]

Identifier: 29141755

GI number: 29141755

Start: 1360078

End: 1361283

Strand: Reverse

Name: ydhC [H]

Synonym: t1296

Alternate gene names: 29141755

Gene position: 1361283-1360078 (Counterclockwise)

Preceding gene: 29141757

Following gene: 29141754

Centisome position: 28.41

GC content: 54.48

Gene sequence:

>1206_bases
ATGCAACCTGGAAAAGGTTTTTTAGTCTGGTTAGCCGGCCTTAGCGTGCTGGGATTTCTGGCTACGGACATGTACCTGCC
CGCGTTTGCCGCCATACAGGCGGATTTACAAACGCCTGCCGCCGCTGTCAGCGCCAGCCTAAGCCTGTTTTTAGCTGGCT
TTGCCGTCGCGCAACTACTTTGGGGACCGCTATCGGATCGTTATGGCCGTAAACCGATTTTACTGCTGGGGTTATCTATC
TTTGCACTCGGAAGTCTGGGGATGCTGTGGGTAGAAAGCGCGGCAGCACTGCTGACGCTGCGCTTTGTGCAGGCCGTCGG
CGTTTGTGCGGCAACGGTAATCTGGCAAGCGCTGGTGACCGATTATTATCCTTCGCAAAAAATTAACCGTATCTTCGCCA
CGATCATGCCACTGGTGGGATTATCCCCGGCGCTTGCGCCCTTACTGGGAAGCTGGATACTGACGCATTTCTCATGGCAG
GTGATTTTCGCCACCCTGTTCGTGATTACGTTGTTGCTGATGTTGCCGGCGCTGCGCTTAAAACCATCGGTAAAAGCGCG
TACCGAAGGACAGGATAAACTCACTTTCGCGACGTTGTTACGCTCTAAAACCTATCGCGGTAATGTGCTGATTTATGCCG
CCTGTTCCGCCAGCTTTTTTGCGTGGCTAACAGGGTCCCCGTTTATTCTCAGCGCGATGGGTTACAGCCCGGCAGTGATT
GGCCTGAGCTATGTTCCTCAAACCATCGCTTTTCTGATTGGCGGATATGGTTGCCGCGCGGCGCTACAAAAATGGCAGGG
CTACCAATTGCTTCCGTGGCTGTTAGGGCTGTATGCGCTGAGCGTTATCGCCACCTGGGGAGCGGGCCTTCTGAATAATG
CCTCACTGGTGGAGATCCTGATTCCTTTCTGCGTAATGGCGATTGCTAATGGCGCAATCTACCCTATCGTCGTCGCGCAA
GCGTTACGCCCTTTCCCTCAAGCCACGGGGCGCGCTGCGGCGCTACAAAATACGCTGCAACTGGGGTTATGTTTCCTGGC
AAGCCTGGTGGTTTCATGGCTCATCAGCACGCCGCTGCTGACCACCACCAGCGTAATGCTCTCTACCGTTGTTCTGGCGG
CGTTAGGTTACAAAATGCAGTCTCATGCAGATTGCGCTGAGACTGGATTTCCCCATGCCAATGTCGCCCACGACAAGTCT
CACTAA

Upstream 100 bases:

>100_bases
AAAATTTTGAATTCACTGGACAAATATTAACGTTTCACAACCGTAATTTCACTCCCTACACTCTGCGACAATGTCTGTCT
GATAAGAAAGAGAAACAAAT

Downstream 100 bases:

>100_bases
AGACTTGTTAACCGCTGGTAATTAGCACGCTAACAATTTTCGGTTGAATCATCAAAAATTGCGGCCTATACTGATTCCCG
GTTGTTATATTACGATAATT

Product: inner membrane transport protein YdhC

Products: Proton [Cytoplasm]; drug [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 401; Mature: 401

Protein sequence:

>401_residues
MQPGKGFLVWLAGLSVLGFLATDMYLPAFAAIQADLQTPAAAVSASLSLFLAGFAVAQLLWGPLSDRYGRKPILLLGLSI
FALGSLGMLWVESAAALLTLRFVQAVGVCAATVIWQALVTDYYPSQKINRIFATIMPLVGLSPALAPLLGSWILTHFSWQ
VIFATLFVITLLLMLPALRLKPSVKARTEGQDKLTFATLLRSKTYRGNVLIYAACSASFFAWLTGSPFILSAMGYSPAVI
GLSYVPQTIAFLIGGYGCRAALQKWQGYQLLPWLLGLYALSVIATWGAGLLNNASLVEILIPFCVMAIANGAIYPIVVAQ
ALRPFPQATGRAAALQNTLQLGLCFLASLVVSWLISTPLLTTTSVMLSTVVLAALGYKMQSHADCAETGFPHANVAHDKS
H

Sequences:

>Translated_401_residues
MQPGKGFLVWLAGLSVLGFLATDMYLPAFAAIQADLQTPAAAVSASLSLFLAGFAVAQLLWGPLSDRYGRKPILLLGLSI
FALGSLGMLWVESAAALLTLRFVQAVGVCAATVIWQALVTDYYPSQKINRIFATIMPLVGLSPALAPLLGSWILTHFSWQ
VIFATLFVITLLLMLPALRLKPSVKARTEGQDKLTFATLLRSKTYRGNVLIYAACSASFFAWLTGSPFILSAMGYSPAVI
GLSYVPQTIAFLIGGYGCRAALQKWQGYQLLPWLLGLYALSVIATWGAGLLNNASLVEILIPFCVMAIANGAIYPIVVAQ
ALRPFPQATGRAAALQNTLQLGLCFLASLVVSWLISTPLLTTTSVMLSTVVLAALGYKMQSHADCAETGFPHANVAHDKS
H
>Mature_401_residues
MQPGKGFLVWLAGLSVLGFLATDMYLPAFAAIQADLQTPAAAVSASLSLFLAGFAVAQLLWGPLSDRYGRKPILLLGLSI
FALGSLGMLWVESAAALLTLRFVQAVGVCAATVIWQALVTDYYPSQKINRIFATIMPLVGLSPALAPLLGSWILTHFSWQ
VIFATLFVITLLLMLPALRLKPSVKARTEGQDKLTFATLLRSKTYRGNVLIYAACSASFFAWLTGSPFILSAMGYSPAVI
GLSYVPQTIAFLIGGYGCRAALQKWQGYQLLPWLLGLYALSVIATWGAGLLNNASLVEILIPFCVMAIANGAIYPIVVAQ
ALRPFPQATGRAAALQNTLQLGLCFLASLVVSWLISTPLLTTTSVMLSTVVLAALGYKMQSHADCAETGFPHANVAHDKS
H

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Bcr/CmlA family [H]

Homologues:

Organism=Escherichia coli, GI48994889, Length=403, Percent_Identity=84.863523573201, Blast_Score=671, Evalue=0.0,
Organism=Escherichia coli, GI1788509, Length=344, Percent_Identity=28.7790697674419, Blast_Score=123, Evalue=2e-29,
Organism=Escherichia coli, GI87082312, Length=346, Percent_Identity=27.1676300578035, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI1790146, Length=217, Percent_Identity=28.5714285714286, Blast_Score=87, Evalue=1e-18,
Organism=Escherichia coli, GI1790794, Length=223, Percent_Identity=26.9058295964126, Blast_Score=85, Evalue=8e-18,
Organism=Escherichia coli, GI1787065, Length=220, Percent_Identity=25.9090909090909, Blast_Score=78, Evalue=1e-15,
Organism=Saccharomyces cerevisiae, GI6319657, Length=163, Percent_Identity=27.6073619631902, Blast_Score=65, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004812
- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 42871; Mature: 42871

Theoretical pI: Translated: 9.57; Mature: 9.57

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHCCHHHHCCCHHHCCCCCCCCCCCCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHCCHHHHCCCHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; drug [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + drug [Cytoplasm] = Proton [Cytoplasm] + drug [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]