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The map label for this gene is ttrR [H]

Identifier: 29141716

GI number: 29141716

Start: 1327570

End: 1328190

Strand: Direct

Name: ttrR [H]

Synonym: t1255

Alternate gene names: 29141716

Gene position: 1327570-1328190 (Clockwise)

Preceding gene: 29141715

Following gene: 29141717

Centisome position: 27.7

GC content: 55.39

Gene sequence:

>621_bases
ATGGCGACAATTCATCTACTGGATGATGATACGGCGGTCACTAACGCGTGCGCGTTTTTACTGGAAAGTCTGGGATATGA
CGTAAAATGCTGGACGCAGGGGGCGGATTTTTTGGCGCAGGCCAGTCTGTATCAGGCCGGGGTCGTATTACTGGATATGC
GAATGCCGGTACTGGATGGGCAGGGCGTTCATGATGCGTTGCGCCAGTGCGGAAGTACCCTGGCGGTTGTTTTTCTTACC
GGGCATGGCGATGTACCGATGGCCGTGGAGCAGATGAAACGCGGCGCCGTCGATTTTCTGCAAAAACCGGTATCGGTAAA
ACCGCTACAGGCGGCGCTGGAGCGTGCGCTGACGGTTTCATCGGCAGCGGTGGCGCGCCGTGAGATTATACTGTGTTACC
AGCAGTTGACGCCGAAAGAGCGTGAGCTGGCCAGCCTGGTGGCAAAAGGGTTTATGAACCGTGAAATTGCGGAAGCGATG
AATATCGCGGTGCGTACCGTAGAGGTGCACCGCGCCAGAGTCATGGAAAAAATGCAGGCCGGTAGCCTGGCGGAACTGAT
TAGGCGTTTCGAAAAAATGGCCTCGCCAGAGACCAGAATACGAACAACGTATGAGCCATGA

Upstream 100 bases:

>100_bases
TATGGGCGGGGCGATATCAGCATCAGGAACCAGACCGCGCCGGACGGTCTGTCGGGAACGGTGGTCACGATACATTTCTT
ACATGAACATGGGGGCAGGG

Downstream 100 bases:

>100_bases
ATAATAAACTGCGTTATTTCTTTGATTTGCATCAAATTTTGTTTAATTGAGAAGACTGTTATATTCTGTTGGTTTGAGCT
GGCGACGAGTAAAACGTATG

Product: two-component response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 206; Mature: 205

Protein sequence:

>206_residues
MATIHLLDDDTAVTNACAFLLESLGYDVKCWTQGADFLAQASLYQAGVVLLDMRMPVLDGQGVHDALRQCGSTLAVVFLT
GHGDVPMAVEQMKRGAVDFLQKPVSVKPLQAALERALTVSSAAVARREIILCYQQLTPKERELASLVAKGFMNREIAEAM
NIAVRTVEVHRARVMEKMQAGSLAELIRRFEKMASPETRIRTTYEP

Sequences:

>Translated_206_residues
MATIHLLDDDTAVTNACAFLLESLGYDVKCWTQGADFLAQASLYQAGVVLLDMRMPVLDGQGVHDALRQCGSTLAVVFLT
GHGDVPMAVEQMKRGAVDFLQKPVSVKPLQAALERALTVSSAAVARREIILCYQQLTPKERELASLVAKGFMNREIAEAM
NIAVRTVEVHRARVMEKMQAGSLAELIRRFEKMASPETRIRTTYEP
>Mature_205_residues
ATIHLLDDDTAVTNACAFLLESLGYDVKCWTQGADFLAQASLYQAGVVLLDMRMPVLDGQGVHDALRQCGSTLAVVFLTG
HGDVPMAVEQMKRGAVDFLQKPVSVKPLQAALERALTVSSAAVARREIILCYQQLTPKERELASLVAKGFMNREIAEAMN
IAVRTVEVHRARVMEKMQAGSLAELIRRFEKMASPETRIRTTYEP

Specific function: FixJ, when activated by fixL, induces the expression of both nifA, required for activation of classical nif and fix genes, and fixK, required for fixN activation [H]

COG id: COG4566

COG function: function code T; Response regulator

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1790102, Length=197, Percent_Identity=32.48730964467, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI1790437, Length=114, Percent_Identity=34.2105263157895, Blast_Score=65, Evalue=3e-12,
Organism=Escherichia coli, GI1788905, Length=150, Percent_Identity=32, Blast_Score=64, Evalue=7e-12,
Organism=Escherichia coli, GI1790299, Length=115, Percent_Identity=29.5652173913043, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001789
- InterPro:   IPR000792
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00196 GerE; PF00072 Response_reg [H]

EC number: NA

Molecular weight: Translated: 22693; Mature: 22562

Theoretical pI: Translated: 6.92; Mature: 6.92

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS00622 HTH_LUXR_1 ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
4.9 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
6.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATIHLLDDDTAVTNACAFLLESLGYDVKCWTQGADFLAQASLYQAGVVLLDMRMPVLDG
CCEEEEECCCHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHCHHEEECCCCCCCC
QGVHDALRQCGSTLAVVFLTGHGDVPMAVEQMKRGAVDFLQKPVSVKPLQAALERALTVS
CCHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
SAAVARREIILCYQQLTPKERELASLVAKGFMNREIAEAMNIAVRTVEVHRARVMEKMQA
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
GSLAELIRRFEKMASPETRIRTTYEP
CCHHHHHHHHHHHCCCCHHCCCCCCC
>Mature Secondary Structure 
ATIHLLDDDTAVTNACAFLLESLGYDVKCWTQGADFLAQASLYQAGVVLLDMRMPVLDG
CEEEEECCCHHHHHHHHHHHHHHCCCEEEECCCHHHHHHHHHHHHCHHEEECCCCCCCC
QGVHDALRQCGSTLAVVFLTGHGDVPMAVEQMKRGAVDFLQKPVSVKPLQAALERALTVS
CCHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHH
SAAVARREIILCYQQLTPKERELASLVAKGFMNREIAEAMNIAVRTVEVHRARVMEKMQA
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
GSLAELIRRFEKMASPETRIRTTYEP
CCHHHHHHHHHHHCCCCHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2046550 [H]