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The map label for this gene is infC [H]

Identifier: 29141678

GI number: 29141678

Start: 1282577

End: 1283119

Strand: Direct

Name: infC [H]

Synonym: t1214

Alternate gene names: 29141678

Gene position: 1282577-1283119 (Clockwise)

Preceding gene: 29141677

Following gene: 29141679

Centisome position: 26.77

GC content: 47.51

Gene sequence:

>543_bases
ATTAAAGGCGGAAAACGAGTTCAAACGGCGCGTCCGAATCGTATTAATAGCGAAATTCGCGCGCAAGAAGTTCGCTTAAC
AGGTCTGGAAGGCGAGCAGCTTGGTATTGTGAGTCTGAGAGAAGCTCTGGAAAAAGCTGAAGAAGCCGGAGTAGACTTAG
TCGAAATCAGCCCTAACGCCGAGCCGCCGGTTTGTCGTATAATGGATTACGGCAAATTCCTCTATGAAAAGAGTAAGTCT
TCTAAGGAACAGAAGAAAAAGCAAAAAGTTATCCAGGTGAAGGAAATTAAATTCCGTCCTGGGACAGATGAAGGCGACTA
TCAGGTAAAACTCCGCAGCCTGATTCGCTTTCTCGAAGAGGGCGATAAGGCCAAGATCACGCTGCGTTTCCGCGGTCGTG
AAATGGCCCACCAGCAAATCGGTATGGAAGTGCTTAATCGCGTGAAAAACGATTTGCAAGAACTGGCAGTGGTCGAATCC
TTCCCAACGAAGATCGAAGGCCGTCAGATGATCATGGTGCTTGCTCCTAAGAAGAAACAGTAA

Upstream 100 bases:

>100_bases
CCGCGGTAAAGACCTGGGCAGTCTGGACGTAAATGACGTGATTGAGAAGCTGCAACAAGAGATTCGCAGCCGCAGTCTTC
AACAACTGGAGGAATAAAGT

Downstream 100 bases:

>100_bases
GGCCTTCAAGTAACAATTCTGTGAAGCCTTCGGGCTTCACAGGTTTTGTTCGCCTATGTTTCGTTTATTAACAATGCGAA
GTGGAAGTTATTAAAATGCC

Product: translation initiation factor IF-3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 180; Mature: 180

Protein sequence:

>180_residues
MKGGKRVQTARPNRINSEIRAQEVRLTGLEGEQLGIVSLREALEKAEEAGVDLVEISPNAEPPVCRIMDYGKFLYEKSKS
SKEQKKKQKVIQVKEIKFRPGTDEGDYQVKLRSLIRFLEEGDKAKITLRFRGREMAHQQIGMEVLNRVKNDLQELAVVES
FPTKIEGRQMIMVLAPKKKQ

Sequences:

>Translated_180_residues
MKGGKRVQTARPNRINSEIRAQEVRLTGLEGEQLGIVSLREALEKAEEAGVDLVEISPNAEPPVCRIMDYGKFLYEKSKS
SKEQKKKQKVIQVKEIKFRPGTDEGDYQVKLRSLIRFLEEGDKAKITLRFRGREMAHQQIGMEVLNRVKNDLQELAVVES
FPTKIEGRQMIMVLAPKKKQ
>Mature_180_residues
MKGGKRVQTARPNRINSEIRAQEVRLTGLEGEQLGIVSLREALEKAEEAGVDLVEISPNAEPPVCRIMDYGKFLYEKSKS
SKEQKKKQKVIQVKEIKFRPGTDEGDYQVKLRSLIRFLEEGDKAKITLRFRGREMAHQQIGMEVLNRVKNDLQELAVVES
FPTKIEGRQMIMVLAPKKKQ

Specific function: IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins [H]

COG id: COG0290

COG function: function code J; Translation initiation factor 3 (IF-3)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the IF-3 family [H]

Homologues:

Organism=Escherichia coli, GI1788012, Length=180, Percent_Identity=98.8888888888889, Blast_Score=356, Evalue=1e-100,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019813
- InterPro:   IPR001288
- InterPro:   IPR019815
- InterPro:   IPR019814 [H]

Pfam domain/function: PF00707 IF3_C; PF05198 IF3_N [H]

EC number: NA

Molecular weight: Translated: 20593; Mature: 20593

Theoretical pI: Translated: 10.31; Mature: 10.31

Prosite motif: PS00938 IF3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGGKRVQTARPNRINSEIRAQEVRLTGLEGEQLGIVSLREALEKAEEAGVDLVEISPNA
CCCCCCCCCCCCCCCCHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCC
EPPVCRIMDYGKFLYEKSKSSKEQKKKQKVIQVKEIKFRPGTDEGDYQVKLRSLIRFLEE
CCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHC
GDKAKITLRFRGREMAHQQIGMEVLNRVKNDLQELAVVESFPTKIEGRQMIMVLAPKKKQ
CCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCC
>Mature Secondary Structure
MKGGKRVQTARPNRINSEIRAQEVRLTGLEGEQLGIVSLREALEKAEEAGVDLVEISPNA
CCCCCCCCCCCCCCCCHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCC
EPPVCRIMDYGKFLYEKSKSSKEQKKKQKVIQVKEIKFRPGTDEGDYQVKLRSLIRFLEE
CCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHC
GDKAKITLRFRGREMAHQQIGMEVLNRVKNDLQELAVVESFPTKIEGRQMIMVLAPKKKQ
CCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA