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The map label for this gene is argD [H]

Identifier: 29141648

GI number: 29141648

Start: 1250072

End: 1251298

Strand: Direct

Name: argD [H]

Synonym: t1182

Alternate gene names: 29141648

Gene position: 1250072-1251298 (Clockwise)

Preceding gene: 29141645

Following gene: 29141649

Centisome position: 26.09

GC content: 55.91

Gene sequence:

>1227_bases
ATGTCTCTGTCAGTTACGCGCGAAAACTTTGATGAATGGATGGTGCCGGTATATGTTCCCGCGCCTTTTATTCCTGTACG
CGGAGAAGGCTCACGCCTGTGGGATCAGCAGGGGAAAGAGTACATTGATTTTGCTGGCGGGATTGCGGTCAACGCATTGG
GACATGCGCATCCGGCGCTGCGCGAGGCGTTAAATGAACAGGCGAATCGCTTCTGGCATACCGGGAACGGTTACACCAAT
GAACCGGCGCTGCGACTGGCGAAAAAACTGATCGACGCGACCTTCGCCGAACGCGTTTTCTTTTGTAATTCAGGCGCTGA
AGCAAATGAAGCTGCATTAAAACTGGCGCGCAAATATGCCCACGATCGTGTTGGCAACCATAAAAGCGGCATTGTGGCCT
TTAAAAACGCGTTCCATGGCCGCACGCTCTTTACCGTCAGCGCTGGCGGTCAACCCACCTATTCACAGGACTTTGCGCCG
CTGCCGCCGGATATTCGTCATGCAGCCTATAACGATCTGAACTCCGCCAGCGCGCTCATTGATGACAATACCTGCGCCGT
AATCGTAGAGCCTGTGCAGGGCGAGGGCGGCGTGATCCCCGCCACGAACGCTTTTTTGCAGGGGCTGCGTGAATTGTGCG
ACCGGCATCAGGCGTTACTGATTTTTGATGAGGTGCAGACGGGCGTCGGACGTACCGGCGAACTGTATGCATATATGCAT
TATGGCGTTACGCCCGATATCCTGACGACCGCTAAAGCGTTGGGCGGCGGCTTCCCGATCGGCGCGATGCTGACTACGCA
AGACTATGCCAGCGTCATGACGCCAGGTACGCATGGCACCACCTACGGCGGTAATCCGCTGGCGACGGCAGTTGCCGGAA
AAGTACTGGATATCATCAATACGCCGGAGATGCAAAACGGCGTCAGACAGCGCCACGATGCGTTTATTGAACGTCTAAAT
ACCATTAATGTACGTTTTGGCATGTTCAGTGAAATTCGCGGGCTGGGGCTACTGCTTGGCTGTGTGCTACAGACGGAGTT
TGCCGGAAAAGCCAAACTCATCGCCCAGGAAGCGGCAAAAGCAGGCGTGATGGTGCTCATCGCCGGTGGCGACGTGGTGC
GTTTTGCGCCAGCGTTAAATGTGAGCGACGAGGAGATAGCTACCGGGCTTGATCGTTTTGCCCTGGCGTGCGAACGCCTT
CAGGCGGGAGGCGCATCATGCGGGTGA

Upstream 100 bases:

>100_bases
TTAACGCTGGCTGGCACGAATGCTGCAATCTACATTTACAGCGCAAACACCCATATTAATTAACATATAGATAACTTTAT
TTTTACCAAAAGAGGTCGCT

Downstream 100 bases:

>100_bases
TTCGTCCTGTCGAACATGCGGATATCGCCGCGCTGATGCAGCTTGCAGGCAAAACGGGCGGCGGCTTAACCTCGCTACTG
GCAAATGAAGCGACGCTGGC

Product: bifunctional succinylornithine transaminase/acetylornithine transaminase

Products: NA

Alternate protein names: Succinylornithine aminotransferase [H]

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MSLSVTRENFDEWMVPVYVPAPFIPVRGEGSRLWDQQGKEYIDFAGGIAVNALGHAHPALREALNEQANRFWHTGNGYTN
EPALRLAKKLIDATFAERVFFCNSGAEANEAALKLARKYAHDRVGNHKSGIVAFKNAFHGRTLFTVSAGGQPTYSQDFAP
LPPDIRHAAYNDLNSASALIDDNTCAVIVEPVQGEGGVIPATNAFLQGLRELCDRHQALLIFDEVQTGVGRTGELYAYMH
YGVTPDILTTAKALGGGFPIGAMLTTQDYASVMTPGTHGTTYGGNPLATAVAGKVLDIINTPEMQNGVRQRHDAFIERLN
TINVRFGMFSEIRGLGLLLGCVLQTEFAGKAKLIAQEAAKAGVMVLIAGGDVVRFAPALNVSDEEIATGLDRFALACERL
QAGGASCG

Sequences:

>Translated_408_residues
MSLSVTRENFDEWMVPVYVPAPFIPVRGEGSRLWDQQGKEYIDFAGGIAVNALGHAHPALREALNEQANRFWHTGNGYTN
EPALRLAKKLIDATFAERVFFCNSGAEANEAALKLARKYAHDRVGNHKSGIVAFKNAFHGRTLFTVSAGGQPTYSQDFAP
LPPDIRHAAYNDLNSASALIDDNTCAVIVEPVQGEGGVIPATNAFLQGLRELCDRHQALLIFDEVQTGVGRTGELYAYMH
YGVTPDILTTAKALGGGFPIGAMLTTQDYASVMTPGTHGTTYGGNPLATAVAGKVLDIINTPEMQNGVRQRHDAFIERLN
TINVRFGMFSEIRGLGLLLGCVLQTEFAGKAKLIAQEAAKAGVMVLIAGGDVVRFAPALNVSDEEIATGLDRFALACERL
QAGGASCG
>Mature_407_residues
SLSVTRENFDEWMVPVYVPAPFIPVRGEGSRLWDQQGKEYIDFAGGIAVNALGHAHPALREALNEQANRFWHTGNGYTNE
PALRLAKKLIDATFAERVFFCNSGAEANEAALKLARKYAHDRVGNHKSGIVAFKNAFHGRTLFTVSAGGQPTYSQDFAPL
PPDIRHAAYNDLNSASALIDDNTCAVIVEPVQGEGGVIPATNAFLQGLRELCDRHQALLIFDEVQTGVGRTGELYAYMHY
GVTPDILTTAKALGGGFPIGAMLTTQDYASVMTPGTHGTTYGGNPLATAVAGKVLDIINTPEMQNGVRQRHDAFIERLNT
INVRFGMFSEIRGLGLLLGCVLQTEFAGKAKLIAQEAAKAGVMVLIAGGDVVRFAPALNVSDEEIATGLDRFALACERLQ
AGGASCG

Specific function: Catalyzes the transamination of N(2)-succinylornithine and alpha-ketoglutarate into N(2)-succinylglutamate semialdehyde and glutamate. Can also act as an acetylornithine aminotransferase [H]

COG id: COG4992

COG function: function code E; Ornithine/acetylornithine aminotransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. AstC subfamily [H]

Homologues:

Organism=Homo sapiens, GI4557809, Length=378, Percent_Identity=34.6560846560847, Blast_Score=222, Evalue=6e-58,
Organism=Homo sapiens, GI284507298, Length=293, Percent_Identity=36.8600682593857, Blast_Score=183, Evalue=3e-46,
Organism=Homo sapiens, GI13994255, Length=443, Percent_Identity=26.86230248307, Blast_Score=163, Evalue=2e-40,
Organism=Homo sapiens, GI37574042, Length=422, Percent_Identity=27.4881516587678, Blast_Score=139, Evalue=6e-33,
Organism=Homo sapiens, GI226442705, Length=422, Percent_Identity=26.7772511848341, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI24119277, Length=430, Percent_Identity=26.5116279069767, Blast_Score=127, Evalue=1e-29,
Organism=Homo sapiens, GI226442709, Length=387, Percent_Identity=27.906976744186, Blast_Score=125, Evalue=9e-29,
Organism=Homo sapiens, GI188536080, Length=428, Percent_Identity=24.7663551401869, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI38679950, Length=428, Percent_Identity=24.7663551401869, Blast_Score=99, Evalue=8e-21,
Organism=Homo sapiens, GI38679946, Length=428, Percent_Identity=24.7663551401869, Blast_Score=99, Evalue=8e-21,
Organism=Escherichia coli, GI1788044, Length=406, Percent_Identity=84.9753694581281, Blast_Score=734, Evalue=0.0,
Organism=Escherichia coli, GI1789759, Length=397, Percent_Identity=62.4685138539043, Blast_Score=524, Evalue=1e-150,
Organism=Escherichia coli, GI145693181, Length=391, Percent_Identity=35.8056265984655, Blast_Score=207, Evalue=1e-54,
Organism=Escherichia coli, GI1789016, Length=398, Percent_Identity=33.4170854271357, Blast_Score=205, Evalue=4e-54,
Organism=Escherichia coli, GI1787560, Length=390, Percent_Identity=33.8461538461538, Blast_Score=185, Evalue=5e-48,
Organism=Escherichia coli, GI1786349, Length=312, Percent_Identity=33.6538461538462, Blast_Score=141, Evalue=7e-35,
Organism=Escherichia coli, GI1786991, Length=316, Percent_Identity=33.8607594936709, Blast_Score=134, Evalue=9e-33,
Organism=Caenorhabditis elegans, GI25144271, Length=378, Percent_Identity=34.1269841269841, Blast_Score=232, Evalue=3e-61,
Organism=Caenorhabditis elegans, GI32564660, Length=436, Percent_Identity=28.8990825688073, Blast_Score=186, Evalue=3e-47,
Organism=Caenorhabditis elegans, GI25144274, Length=276, Percent_Identity=34.0579710144928, Blast_Score=172, Evalue=3e-43,
Organism=Caenorhabditis elegans, GI71992977, Length=366, Percent_Identity=28.9617486338798, Blast_Score=126, Evalue=2e-29,
Organism=Caenorhabditis elegans, GI71981843, Length=164, Percent_Identity=31.7073170731707, Blast_Score=93, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI17541228, Length=253, Percent_Identity=28.0632411067194, Blast_Score=93, Evalue=3e-19,
Organism=Saccharomyces cerevisiae, GI6324432, Length=399, Percent_Identity=41.6040100250627, Blast_Score=291, Evalue=1e-79,
Organism=Saccharomyces cerevisiae, GI6323470, Length=422, Percent_Identity=33.6492890995261, Blast_Score=220, Evalue=2e-58,
Organism=Saccharomyces cerevisiae, GI6324386, Length=318, Percent_Identity=30.5031446540881, Blast_Score=115, Evalue=1e-26,
Organism=Saccharomyces cerevisiae, GI6321456, Length=358, Percent_Identity=26.2569832402235, Blast_Score=93, Evalue=7e-20,
Organism=Drosophila melanogaster, GI21357415, Length=379, Percent_Identity=34.0369393139842, Blast_Score=223, Evalue=1e-58,
Organism=Drosophila melanogaster, GI28574759, Length=446, Percent_Identity=30.0448430493274, Blast_Score=185, Evalue=4e-47,
Organism=Drosophila melanogaster, GI161085790, Length=441, Percent_Identity=29.9319727891156, Blast_Score=182, Evalue=3e-46,
Organism=Drosophila melanogaster, GI21356575, Length=363, Percent_Identity=30.0275482093664, Blast_Score=131, Evalue=8e-31,
Organism=Drosophila melanogaster, GI281366494, Length=437, Percent_Identity=23.7986270022883, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24667139, Length=437, Percent_Identity=23.7986270022883, Blast_Score=89, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24667143, Length=437, Percent_Identity=23.7986270022883, Blast_Score=89, Evalue=6e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004636
- InterPro:   IPR005814
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422
- InterPro:   IPR017652 [H]

Pfam domain/function: PF00202 Aminotran_3 [H]

EC number: =2.6.1.81 [H]

Molecular weight: Translated: 43738; Mature: 43607

Theoretical pI: Translated: 6.13; Mature: 6.13

Prosite motif: PS00600 AA_TRANSFER_CLASS_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSLSVTRENFDEWMVPVYVPAPFIPVRGEGSRLWDQQGKEYIDFAGGIAVNALGHAHPAL
CCCCCCHHCHHHCEEEEEECCCEEEECCCCCHHHHHCCCHHHHHCCCCCEEHHHCCCHHH
REALNEQANRFWHTGNGYTNEPALRLAKKLIDATFAERVFFCNSGAEANEAALKLARKYA
HHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHH
HDRVGNHKSGIVAFKNAFHGRTLFTVSAGGQPTYSQDFAPLPPDIRHAAYNDLNSASALI
HHHCCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCCCEEE
DDNTCAVIVEPVQGEGGVIPATNAFLQGLRELCDRHQALLIFDEVQTGVGRTGELYAYMH
CCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEHHHHCCCCCCCEEEEEE
YGVTPDILTTAKALGGGFPIGAMLTTQDYASVMTPGTHGTTYGGNPLATAVAGKVLDIIN
CCCCHHHHHHHHHHCCCCCCCEEEECHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHC
TPEMQNGVRQRHDAFIERLNTINVRFGMFSEIRGLGLLLGCVLQTEFAGKAKLIAQEAAK
CCHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHC
AGVMVLIAGGDVVRFAPALNVSDEEIATGLDRFALACERLQAGGASCG
CCEEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure 
SLSVTRENFDEWMVPVYVPAPFIPVRGEGSRLWDQQGKEYIDFAGGIAVNALGHAHPAL
CCCCCHHCHHHCEEEEEECCCEEEECCCCCHHHHHCCCHHHHHCCCCCEEHHHCCCHHH
REALNEQANRFWHTGNGYTNEPALRLAKKLIDATFAERVFFCNSGAEANEAALKLARKYA
HHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHHHHHHH
HDRVGNHKSGIVAFKNAFHGRTLFTVSAGGQPTYSQDFAPLPPDIRHAAYNDLNSASALI
HHHCCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCCCEEE
DDNTCAVIVEPVQGEGGVIPATNAFLQGLRELCDRHQALLIFDEVQTGVGRTGELYAYMH
CCCCEEEEEEECCCCCCCCCCHHHHHHHHHHHHHCCCEEEEEEHHHHCCCCCCCEEEEEE
YGVTPDILTTAKALGGGFPIGAMLTTQDYASVMTPGTHGTTYGGNPLATAVAGKVLDIIN
CCCCHHHHHHHHHHCCCCCCCEEEECHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHC
TPEMQNGVRQRHDAFIERLNTINVRFGMFSEIRGLGLLLGCVLQTEFAGKAKLIAQEAAK
CCHHHHHHHHHHHHHHHHHHHEEEEECCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHC
AGVMVLIAGGDVVRFAPALNVSDEEIATGLDRFALACERLQAGGASCG
CCEEEEEECCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA