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The map label for this gene is leuE [H]

Identifier: 29141617

GI number: 29141617

Start: 1217767

End: 1218405

Strand: Direct

Name: leuE [H]

Synonym: t1148

Alternate gene names: 29141617

Gene position: 1217767-1218405 (Clockwise)

Preceding gene: 29141616

Following gene: 29141618

Centisome position: 25.41

GC content: 46.17

Gene sequence:

>639_bases
GTGTTCGCGGAGTATGGTGTTCTGAATTATTGGACGTACCTGGTCGGGGCGATTTTTATCGTTCTGGTACCAGGGCCGAA
TACGCTTTTTGTGCTTAAAAATAGCGTGGGACGCGGGGTTAAAGGAGGATATCTTGCCGCATGTGGCGTGTTTATCGGTG
ATGCGATATTAATGTTTCTGGCGTATGCGGGCGTGGCGACGCTGATCAAAACAACGCCGGTTCTGTTTAACATTGTTCGC
TATCTCGGCGCGTTTTATCTGCTCTACCTTGGCGCAAAAATCCTTTACGCCACTCTGACCTCAAAAGGGCGTGCGGCGAC
GGAAACGGTAGTTCCTTTTGGCGCTATTTTTAAGCGTGCTTTAATTCTTAGCCTGACGAATCCTAAAGCCATACTTTTTT
ATGTTTCCTTTTTTGTGCAATTTATTGATGTTACTGCGCCGCATACTGGGGTGTCATTTTTTATTTTGGCCACCACCCTT
GAAATCGTCAGTTTTTGCTATCTGAGCTTTTTAATTCTTTCTGGCGCTTTTGTAACCCACTATATTGGTACCAAAAAGAA
ACTGGCAAAAGTGGGCAATTCGTTGATTGGCCTTCTTTTCGTCGGATTTGCCGCCCGGCTGGCAACGCTCCAGTCTTAA

Upstream 100 bases:

>100_bases
ATAGCGGCTGGAGAGACGTGGTTTCGCTTCCCATCTTCCGATGCATTCGTTAGCATACTGTTTCGCAGCTAAGCGTAAAT
GTTTTCAGGAAGAGGTTAAT

Downstream 100 bases:

>100_bases
CCCCCTGGACCCGTCGTGAACGGCGGGTCATTGCTCTCCTTTCGGTTTTATTGCGTGGAAAACAGCAAAATAGTAACCAA
TAAATGGTATTTAAAATGCT

Product: leucine export protein LeuE

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 212

Protein sequence:

>212_residues
MFAEYGVLNYWTYLVGAIFIVLVPGPNTLFVLKNSVGRGVKGGYLAACGVFIGDAILMFLAYAGVATLIKTTPVLFNIVR
YLGAFYLLYLGAKILYATLTSKGRAATETVVPFGAIFKRALILSLTNPKAILFYVSFFVQFIDVTAPHTGVSFFILATTL
EIVSFCYLSFLILSGAFVTHYIGTKKKLAKVGNSLIGLLFVGFAARLATLQS

Sequences:

>Translated_212_residues
MFAEYGVLNYWTYLVGAIFIVLVPGPNTLFVLKNSVGRGVKGGYLAACGVFIGDAILMFLAYAGVATLIKTTPVLFNIVR
YLGAFYLLYLGAKILYATLTSKGRAATETVVPFGAIFKRALILSLTNPKAILFYVSFFVQFIDVTAPHTGVSFFILATTL
EIVSFCYLSFLILSGAFVTHYIGTKKKLAKVGNSLIGLLFVGFAARLATLQS
>Mature_212_residues
MFAEYGVLNYWTYLVGAIFIVLVPGPNTLFVLKNSVGRGVKGGYLAACGVFIGDAILMFLAYAGVATLIKTTPVLFNIVR
YLGAFYLLYLGAKILYATLTSKGRAATETVVPFGAIFKRALILSLTNPKAILFYVSFFVQFIDVTAPHTGVSFFILATTL
EIVSFCYLSFLILSGAFVTHYIGTKKKLAKVGNSLIGLLFVGFAARLATLQS

Specific function: Exporter of leucine [H]

COG id: COG1280

COG function: function code E; Putative threonine efflux protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI1788099, Length=212, Percent_Identity=87.2641509433962, Blast_Score=365, Evalue=1e-102,
Organism=Escherichia coli, GI48994979, Length=205, Percent_Identity=28.2926829268293, Blast_Score=74, Evalue=5e-15,
Organism=Escherichia coli, GI1786522, Length=199, Percent_Identity=28.1407035175879, Blast_Score=70, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 22947; Mature: 22947

Theoretical pI: Translated: 10.12; Mature: 10.12

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFAEYGVLNYWTYLVGAIFIVLVPGPNTLFVLKNSVGRGVKGGYLAACGVFIGDAILMFL
CCCCCHHHHHHHHHHHHHHEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHH
AYAGVATLIKTTPVLFNIVRYLGAFYLLYLGAKILYATLTSKGRAATETVVPFGAIFKRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
LILSLTNPKAILFYVSFFVQFIDVTAPHTGVSFFILATTLEIVSFCYLSFLILSGAFVTH
HHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YIGTKKKLAKVGNSLIGLLFVGFAARLATLQS
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MFAEYGVLNYWTYLVGAIFIVLVPGPNTLFVLKNSVGRGVKGGYLAACGVFIGDAILMFL
CCCCCHHHHHHHHHHHHHHEEEECCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHH
AYAGVATLIKTTPVLFNIVRYLGAFYLLYLGAKILYATLTSKGRAATETVVPFGAIFKRA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHH
LILSLTNPKAILFYVSFFVQFIDVTAPHTGVSFFILATTLEIVSFCYLSFLILSGAFVTH
HHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YIGTKKKLAKVGNSLIGLLFVGFAARLATLQS
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA