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The map label for this gene is aadA [H]

Identifier: 29141611

GI number: 29141611

Start: 1213763

End: 1214551

Strand: Direct

Name: aadA [H]

Synonym: t1142

Alternate gene names: 29141611

Gene position: 1213763-1214551 (Clockwise)

Preceding gene: 29141610

Following gene: 29141612

Centisome position: 25.33

GC content: 54.25

Gene sequence:

>789_bases
ATGACGCTGTCCATACCGCCCTCGATTCAATGCCAAACGGAAGCGGCGTGTCGCCTGATTACTCGTGTCACAGGCGATAC
GTTGCGTGCTATTCATTTATATGGTTCCGCTGTCGCGGGCGATCTGAAGCCAAACAGCGACATTGATCTGCTGGTGACAA
TATGCCAGCCGCTGACGGAGACCCAACGCGCAACGCTGATGCAGGAATTGCTGGCGCTTTCATCGCCGCCGGGGGCGTCA
GCAGAAAAACGCGCTCTGGAGGTCACTGTCGTGCTTTATTCGCAGCTGGTTCCCTGGTGTTTTCCACCTTCCCGGGAAAT
GCAATTTGGCGAGTGGCTAAGAGAGGACATTTATCAGGGGATTTATGAACCAGCGCAGCAGGACTGGGACATGGTGTTAC
TGATAACCCAAATTCTGGAAACCAGTATACCGCTAAAGGGAGAACGCGCGGAACGGCTGTTCACGCCAGCCCCTGCGGCG
CAGTTGCTGAAGGCCTTGCGTTATCCCCTCGACCTTTGGCAATCCACGGCAGATGTGCAGGGAGATGAGTATCATATCGT
TTTAACCCTGGCGCGTATCTGGTACACCCTTTCTACCGGGAGATTTACCTCTAAGGATGCGGCGGCTGACTGGCTGTTAC
CTCAGTTGCCAGAAGAGTATGCTGCTACGTTGCGTGCGGCGCAGCGTGAATATTTAGGTCTGGAGCAACAGGACTGGCAT
ATTTTGCTGCCTGCGGTCGTACGCTTTGTGGATTTTGCGAAAGCGTACATCCCCACGCAGTTCACATAA

Upstream 100 bases:

>100_bases
GCAATGTTAAAAGCTCGCTATGAATAGCGAGCTTTTTTTCTGCCGTTATGCCATATTTCTGGCAATCAATATAAAAAATA
CCTGCGCCCCCGGAGCAACG

Downstream 100 bases:

>100_bases
GATGCCCCAGGACGTCTGTCAGGTTGCGCAAACGGCGTTCCTCAACTACTACTTAATAGGTTCTCATCGCTGAAGTAAGC
AGATGATCTTATGCGGGCCA

Product: aminoglycoside resistance protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 262; Mature: 261

Protein sequence:

>262_residues
MTLSIPPSIQCQTEAACRLITRVTGDTLRAIHLYGSAVAGDLKPNSDIDLLVTICQPLTETQRATLMQELLALSSPPGAS
AEKRALEVTVVLYSQLVPWCFPPSREMQFGEWLREDIYQGIYEPAQQDWDMVLLITQILETSIPLKGERAERLFTPAPAA
QLLKALRYPLDLWQSTADVQGDEYHIVLTLARIWYTLSTGRFTSKDAAADWLLPQLPEEYAATLRAAQREYLGLEQQDWH
ILLPAVVRFVDFAKAYIPTQFT

Sequences:

>Translated_262_residues
MTLSIPPSIQCQTEAACRLITRVTGDTLRAIHLYGSAVAGDLKPNSDIDLLVTICQPLTETQRATLMQELLALSSPPGAS
AEKRALEVTVVLYSQLVPWCFPPSREMQFGEWLREDIYQGIYEPAQQDWDMVLLITQILETSIPLKGERAERLFTPAPAA
QLLKALRYPLDLWQSTADVQGDEYHIVLTLARIWYTLSTGRFTSKDAAADWLLPQLPEEYAATLRAAQREYLGLEQQDWH
ILLPAVVRFVDFAKAYIPTQFT
>Mature_261_residues
TLSIPPSIQCQTEAACRLITRVTGDTLRAIHLYGSAVAGDLKPNSDIDLLVTICQPLTETQRATLMQELLALSSPPGASA
EKRALEVTVVLYSQLVPWCFPPSREMQFGEWLREDIYQGIYEPAQQDWDMVLLITQILETSIPLKGERAERLFTPAPAAQ
LLKALRYPLDLWQSTADVQGDEYHIVLTLARIWYTLSTGRFTSKDAAADWLLPQLPEEYAATLRAAQREYLGLEQQDWHI
LLPAVVRFVDFAKAYIPTQFT

Specific function: Mediates bacterial resistance to the antibiotics streptomycin and spectomycin [H]

COG id: COG1708

COG function: function code R; Predicted nucleotidyltransferases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002934 [H]

Pfam domain/function: PF01909 NTP_transf_2 [H]

EC number: =2.7.7.47 [H]

Molecular weight: Translated: 29536; Mature: 29405

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLSIPPSIQCQTEAACRLITRVTGDTLRAIHLYGSAVAGDLKPNSDIDLLVTICQPLTE
CCCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
TQRATLMQELLALSSPPGASAEKRALEVTVVLYSQLVPWCFPPSREMQFGEWLREDIYQG
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
IYEPAQQDWDMVLLITQILETSIPLKGERAERLFTPAPAAQLLKALRYPLDLWQSTADVQ
HHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHCCCCCHHHHHHHHHCCHHHHHHHCCCC
GDEYHIVLTLARIWYTLSTGRFTSKDAAADWLLPQLPEEYAATLRAAQREYLGLEQQDWH
CCCEEEHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCE
ILLPAVVRFVDFAKAYIPTQFT
EHHHHHHHHHHHHHHHCCCCCC
>Mature Secondary Structure 
TLSIPPSIQCQTEAACRLITRVTGDTLRAIHLYGSAVAGDLKPNSDIDLLVTICQPLTE
CCCCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
TQRATLMQELLALSSPPGASAEKRALEVTVVLYSQLVPWCFPPSREMQFGEWLREDIYQG
HHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHH
IYEPAQQDWDMVLLITQILETSIPLKGERAERLFTPAPAAQLLKALRYPLDLWQSTADVQ
HHHHHHCCCHHHHHHHHHHHHCCCCCCCHHHHHCCCCCHHHHHHHHHCCHHHHHHHCCCC
GDEYHIVLTLARIWYTLSTGRFTSKDAAADWLLPQLPEEYAATLRAAQREYLGLEQQDWH
CCCEEEHHHHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCE
ILLPAVVRFVDFAKAYIPTQFT
EHHHHHHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 3054482; 2997737; 2986186; 3037494; 2821509; 2823258; 2188588 [H]