Click here to switch to the map view.

The map label for this gene is dsbB

Identifier: 29141545

GI number: 29141545

Start: 1150486

End: 1151016

Strand: Reverse

Name: dsbB

Synonym: t1070

Alternate gene names: 29141545

Gene position: 1151016-1150486 (Counterclockwise)

Preceding gene: 29141546

Following gene: 29141544

Centisome position: 24.02

GC content: 54.43

Gene sequence:

>531_bases
ATGTTGCGATTTTTAAACCAGTGCTCACGGGGTCGGGGCGCATGGTTACTGATGGCGTTTACCGCCCTGGCGCTGGAAAT
GGTGGCGCTGTGGTTCCAGCACGTCATGTTACTTAAACCTTGCGTGCTATGTATTTACGAACGTTGCGCCCTGTTTGGCG
TGATGGGCGCGGGTCTGGTCGGCGCAATAGCGCCGAAAACGCCGCTGCGATACGTGGCAATGGTTATCTGGATTTACAGC
GCCTGGCGGGGTCTACAACTGGCGTATGAACATACGATGATTCAGTTGCATCCCTCGCCGTTCATGACCTGTGACTTTAT
GGCGCGCTTTCCAGACTGGTTACCGTTGGGTAAATGGCTACCGCAGGTGTTTGTGGCATCCGGTGATTGCGCCGAGCGCC
AGTGGTCGTTTTTAACGCTGGAGATGCCGCAATGGCTGTTGGGGATCTTTGCCGCTTACCTTGTGGTAGCGATAGCTGTC
GTCATAGCTCAGGCATTTAAGCCTAAAAAACGCGACCTGTTCGGTCGTTGA

Upstream 100 bases:

>100_bases
TGATAATTATCCAATTACACATTATTTCATTTCCCGCTAGTGGCGCACGAATTGAATTGGTTTACACTGCGGTCTCTACG
CATGTTGCAGGGAAATTATT

Downstream 100 bases:

>100_bases
TACACACGCTCCTTCGGGAGCGTTTTTTTGCCCGAAGCGTTGTTTGCCAGTGATTAAAAGGTGTATATTAAATACATCTT
TTAATCACCACATCAGGGAG

Product: disulfide bond formation protein B

Products: NA

Alternate protein names: Disulfide oxidoreductase

Number of amino acids: Translated: 176; Mature: 176

Protein sequence:

>176_residues
MLRFLNQCSRGRGAWLLMAFTALALEMVALWFQHVMLLKPCVLCIYERCALFGVMGAGLVGAIAPKTPLRYVAMVIWIYS
AWRGLQLAYEHTMIQLHPSPFMTCDFMARFPDWLPLGKWLPQVFVASGDCAERQWSFLTLEMPQWLLGIFAAYLVVAIAV
VIAQAFKPKKRDLFGR

Sequences:

>Translated_176_residues
MLRFLNQCSRGRGAWLLMAFTALALEMVALWFQHVMLLKPCVLCIYERCALFGVMGAGLVGAIAPKTPLRYVAMVIWIYS
AWRGLQLAYEHTMIQLHPSPFMTCDFMARFPDWLPLGKWLPQVFVASGDCAERQWSFLTLEMPQWLLGIFAAYLVVAIAV
VIAQAFKPKKRDLFGR
>Mature_176_residues
MLRFLNQCSRGRGAWLLMAFTALALEMVALWFQHVMLLKPCVLCIYERCALFGVMGAGLVGAIAPKTPLRYVAMVIWIYS
AWRGLQLAYEHTMIQLHPSPFMTCDFMARFPDWLPLGKWLPQVFVASGDCAERQWSFLTLEMPQWLLGIFAAYLVVAIAV
VIAQAFKPKKRDLFGR

Specific function: Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein

COG id: COG1495

COG function: function code O; Disulfide bond formation protein DsbB

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DsbB family

Homologues:

Organism=Escherichia coli, GI1787433, Length=176, Percent_Identity=85.2272727272727, Blast_Score=317, Evalue=4e-88,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): DSBB_SALCH (Q57NK5)

Other databases:

- EMBL:   AE017220
- RefSeq:   YP_216787.1
- ProteinModelPortal:   Q57NK5
- SMR:   Q57NK5
- GeneID:   3334276
- GenomeReviews:   AE017220_GR
- KEGG:   sec:SC1800
- HOGENOM:   HBG637909
- OMA:   ALYFQHV
- ProtClustDB:   PRK01749
- BioCyc:   SENT321314:SCH_1800-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_00286
- InterPro:   IPR003752
- InterPro:   IPR022920

Pfam domain/function: PF02600 DsbB

EC number: NA

Molecular weight: Translated: 20063; Mature: 20063

Theoretical pI: Translated: 9.33; Mature: 9.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xdecf80c)-; HASH(0xd830600)-; HASH(0xd32988c)-; HASH(0xc95716c)-;

Cys/Met content:

3.4 %Cys     (Translated Protein)
5.7 %Met     (Translated Protein)
9.1 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
5.7 %Met     (Mature Protein)
9.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRFLNQCSRGRGAWLLMAFTALALEMVALWFQHVMLLKPCVLCIYERCALFGVMGAGLV
CCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAIAPKTPLRYVAMVIWIYSAWRGLQLAYEHTMIQLHPSPFMTCDFMARFPDWLPLGKWL
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHCCCCCCHHHHH
PQVFVASGDCAERQWSFLTLEMPQWLLGIFAAYLVVAIAVVIAQAFKPKKRDLFGR
HHHHHCCCCHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCH
>Mature Secondary Structure
MLRFLNQCSRGRGAWLLMAFTALALEMVALWFQHVMLLKPCVLCIYERCALFGVMGAGLV
CCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
GAIAPKTPLRYVAMVIWIYSAWRGLQLAYEHTMIQLHPSPFMTCDFMARFPDWLPLGKWL
HHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCHHHHHHHCCCCCCHHHHH
PQVFVASGDCAERQWSFLTLEMPQWLLGIFAAYLVVAIAVVIAQAFKPKKRDLFGR
HHHHHCCCCHHHHHHHHEEEHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA