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The map label for this gene is minC

Identifier: 29141538

GI number: 29141538

Start: 1146737

End: 1147444

Strand: Reverse

Name: minC

Synonym: t1063

Alternate gene names: 29141538

Gene position: 1147444-1146737 (Counterclockwise)

Preceding gene: 29141544

Following gene: 29141537

Centisome position: 23.95

GC content: 51.27

Gene sequence:

>708_bases
ATGTCAAACACGCCAATCGAGCTTAAAGGCAGTAGCTTCACCTTATCAGTGGTTCATTTGCATGAAGCGGAACCAGAGGT
TATTCGTCAGGCGTTAGAAGACAAAATAGCGCAGGCTCCTGCGTTTTTAAAACACGCCCCTGTCGTTATTAACGTTAGCG
GTCTTGAAAGCCCGGTAAACTGGCCGGAACTGCATAAGATCGTGACCTCAACCGGCTTACGCATTATCGGCGTGAGCGGC
TGTAAAGACGCCAGCCTGAAAGTAGAAATCGATCGGATGGGTCTTCCTTTACTGACTGAAGGTAAAGAGAAAGCGGTTCG
GCCTGCGCCCGTTGAGCCGGCAACGCCCAGCGAACCGCCGCAAAACGCTAATCCCATCACAAAAACGCGATTAATTGATG
TTCCGGTTCGTTCCGGTCAGCGCATTTATGCTCCACAATGTGATCTGATTGTTACAAGTCACGTCAGCGCTGGCGCAGAG
CTTATCGCTGACGGCAATATCCATGTCTATGGCATGATGAGAGGTCGCGCGCTGGCAGGGGCGAGCGGCGATCGGGAAGC
GCAAATTTTTTGTACCCATCTGACGGCAGAACTGGTCTCTATCGCAGGTGTTTACTGGCTGAGTGATAAAATCCCGGCAG
AATTTTATGGCAAAGCGGCGCGCCTGCGTTTAGCAGACAACGCTTTGACAGTTCAACCGTTGAATTGA

Upstream 100 bases:

>100_bases
GTGACTTGCCTCAATATAATACTGACTATAACATGCCTTCTGGACTTCGGAATATCACTCCGTATCGGAGATGATAAATA
GCAAATTGAGTAAGGCCAGG

Downstream 100 bases:

>100_bases
TCCCTTTTTAACAAGGAATTTTTATGGCACGCATTATTGTTGTTACTTCGGGTAAAGGGGGCGTTGGCAAGACCACCTCC
AGCGCGGCCATCGCTACAGG

Product: septum formation inhibitor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 235; Mature: 234

Protein sequence:

>235_residues
MSNTPIELKGSSFTLSVVHLHEAEPEVIRQALEDKIAQAPAFLKHAPVVINVSGLESPVNWPELHKIVTSTGLRIIGVSG
CKDASLKVEIDRMGLPLLTEGKEKAVRPAPVEPATPSEPPQNANPITKTRLIDVPVRSGQRIYAPQCDLIVTSHVSAGAE
LIADGNIHVYGMMRGRALAGASGDREAQIFCTHLTAELVSIAGVYWLSDKIPAEFYGKAARLRLADNALTVQPLN

Sequences:

>Translated_235_residues
MSNTPIELKGSSFTLSVVHLHEAEPEVIRQALEDKIAQAPAFLKHAPVVINVSGLESPVNWPELHKIVTSTGLRIIGVSG
CKDASLKVEIDRMGLPLLTEGKEKAVRPAPVEPATPSEPPQNANPITKTRLIDVPVRSGQRIYAPQCDLIVTSHVSAGAE
LIADGNIHVYGMMRGRALAGASGDREAQIFCTHLTAELVSIAGVYWLSDKIPAEFYGKAARLRLADNALTVQPLN
>Mature_234_residues
SNTPIELKGSSFTLSVVHLHEAEPEVIRQALEDKIAQAPAFLKHAPVVINVSGLESPVNWPELHKIVTSTGLRIIGVSGC
KDASLKVEIDRMGLPLLTEGKEKAVRPAPVEPATPSEPPQNANPITKTRLIDVPVRSGQRIYAPQCDLIVTSHVSAGAEL
IADGNIHVYGMMRGRALAGASGDREAQIFCTHLTAELVSIAGVYWLSDKIPAEFYGKAARLRLADNALTVQPLN

Specific function: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize ftsZ filaments that have formed before they mature into polar Z rings. Prevents ftsZ polymerization

COG id: COG0850

COG function: function code D; Septum formation inhibitor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the minC family

Homologues:

Organism=Escherichia coli, GI1787424, Length=235, Percent_Identity=84.2553191489362, Blast_Score=410, Evalue=1e-116,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MINC_SALA4 (B5F3S8)

Other databases:

- EMBL:   CP001138
- RefSeq:   YP_002146210.1
- ProteinModelPortal:   B5F3S8
- PRIDE:   B5F3S8
- GeneID:   6796780
- GenomeReviews:   CP001138_GR
- KEGG:   sea:SeAg_B1319
- HOGENOM:   HBG399077
- OMA:   IFCTHLA
- ProtClustDB:   PRK03511
- HAMAP:   MF_00267
- InterPro:   IPR016098
- InterPro:   IPR013033
- InterPro:   IPR007874
- InterPro:   IPR005526
- Gene3D:   G3DSA:2.160.20.70
- TIGRFAMs:   TIGR01222

Pfam domain/function: PF03775 MinC_C; PF05209 MinC_N; SSF63848 MinC_C

EC number: NA

Molecular weight: Translated: 25246; Mature: 25115

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNTPIELKGSSFTLSVVHLHEAEPEVIRQALEDKIAQAPAFLKHAPVVINVSGLESPVN
CCCCCEEEECCEEEEEEEEEECCCHHHHHHHHHHHHHHCCHHHHCCCEEEEECCCCCCCC
WPELHKIVTSTGLRIIGVSGCKDASLKVEIDRMGLPLLTEGKEKAVRPAPVEPATPSEPP
CHHHHHHHHHCCEEEEEECCCCCCEEEEEEECCCCCEEECCCHHCCCCCCCCCCCCCCCC
QNANPITKTRLIDVPVRSGQRIYAPQCDLIVTSHVSAGAELIADGNIHVYGMMRGRALAG
CCCCCCCEEEEEEEECCCCCEEECCCCCEEEECCCCCCEEEEECCCEEEEEEEECEEEEC
ASGDREAQIFCTHLTAELVSIAGVYWLSDKIPAEFYGKAARLRLADNALTVQPLN
CCCCCCEEEEEEHHHHHHHHHHHEEEECCCCCHHHCCCEEEEEEECCEEEEEECC
>Mature Secondary Structure 
SNTPIELKGSSFTLSVVHLHEAEPEVIRQALEDKIAQAPAFLKHAPVVINVSGLESPVN
CCCCEEEECCEEEEEEEEEECCCHHHHHHHHHHHHHHCCHHHHCCCEEEEECCCCCCCC
WPELHKIVTSTGLRIIGVSGCKDASLKVEIDRMGLPLLTEGKEKAVRPAPVEPATPSEPP
CHHHHHHHHHCCEEEEEECCCCCCEEEEEEECCCCCEEECCCHHCCCCCCCCCCCCCCCC
QNANPITKTRLIDVPVRSGQRIYAPQCDLIVTSHVSAGAELIADGNIHVYGMMRGRALAG
CCCCCCCEEEEEEEECCCCCEEECCCCCEEEECCCCCCEEEEECCCEEEEEEEECEEEEC
ASGDREAQIFCTHLTAELVSIAGVYWLSDKIPAEFYGKAARLRLADNALTVQPLN
CCCCCCEEEEEEHHHHHHHHHHHEEEECCCCCHHHCCCEEEEEEECCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA