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The map label for this gene is yoaE [H]

Identifier: 29141524

GI number: 29141524

Start: 1131468

End: 1133027

Strand: Direct

Name: yoaE [H]

Synonym: t1049

Alternate gene names: 29141524

Gene position: 1131468-1133027 (Clockwise)

Preceding gene: 29141518

Following gene: 29141529

Centisome position: 23.61

GC content: 55.51

Gene sequence:

>1560_bases
ATGGAATTATTAATGGATCCCTCAATTTGGGTGGGTTTACTCACGCTCGTCGTCCTGGAAATTGTCCTAGGTATCGATAA
CCTGGTCTTTATCGCGATCCTCGCCGATAAATTGCCGCCAAAGCAGCGTGACAAAGCGCGTCTTATCGGGCTCTCGCTGG
CGCTGATTATGCGTCTGGCGCTGCTGTCCATTATTTCGTGGCTGGTGACCTTAACAAAGTCGCTCTTTACTGTCTGGGAT
TTTACCTTCTCCGGCCGCGATTTAATTATGCTGCTGGGCGGTATATTCCTGCTGTTTAAAGCGACCACCGAGCTGCATGA
ACGTCTGGAAAACCGCGAGCATGACACCGGACACGGTAAAGGCTATGCGAGCTTCTGGGTGGTAGTCACGCAGATTGTCA
TCCTGGATGCGGTCTTCTCGCTGGACGCCGTGATTACGGCGGTAGGTATGGTAAACCATCTGCCGGTTATGATGGCGGCG
GTGGTGATTGCGATGGCGGTGATGCTACTGGCGTCAAAACCGCTGACCCGTTTTGTCAACCAGCATCCGACGGTGGTGGT
GCTCTGTCTGAGTTTCCTGCTGATGATCGGCTTGAGCCTGGTGGCGGAAGGATTTGGTTTCCATATTCCGAAAGGCTACC
TGTACGCGGCAATTGGTTTCTCGATCGTTATCGAGGTGTTTAACCAGATTGCGCGCCGCAACTTTATTCGTCATCAGTCC
ACGTTGCCGCTGCGCGCGCGTACTGCGGACGCTATCCTGCGTCTGATGGGCGGTAAACGTCAGGCGAGTATGCAACATGA
GACGGATAGCCCGGCCGCGATATCGGTGTCGGAAGGCGCCTTCGCCGAAGAAGAACGCTACATGATTAACGGCGTACTGA
CTCTGGCGTCGCGCTCCCTGCGCGGCATTATGACGCCGCGAGGCGAAATTAGTTGGGTGGATGCGAATCTCAGCGTAGCT
GAAATCCGTCAGCAGTTACTCTCTTCTCCGCATAGCCTGTTCCCGGTATGTCGGGGCGAGCTGGATGAAATTATCGGTAT
CGTTCGGGCGAAAGAGTTGCTGGTGGCGCTGGAAGAGGGCGCGGACGTTGCGGCTATCGCCGCCTCTTCCCCGGCGATAG
TGGTGCCGGAAACGCTTGATCCTATCAATCTGTTAGGCGTTTTGCGTCGCGCGCGCGGCAGTTTCGTTATCGTCACTAAC
GAGTTCGGCGTGGTGCAGGGGCTGGTTACGCCGCTGGATGTGCTGGAAGCGATTGCCGGTGAGTTCCCGGATGCCGATGA
AACGCCGGAAATCGTTGCCGATGCCGAGGGCTGGATAGTGAAGGGCGGCACCGATCTTCATGCGTTACAGCAGGCGCTGG
AAGTTGACCATCTGGTGAACGAAGAGGGTGATATTGCGACGGTCGCGGGGTTAGTGATCGCCGCTAATGGCCATATTCCT
CGTGTAGGCGATGTCATTGATGTTCCGCCCCTGCGGATCACCATTGTCGAGGCCAACGACTACCGTGTCGATCTGGTTCG
AATTGTTAAAGAACAGCCTGCCCACGACGAAGAGGAATAA

Upstream 100 bases:

>100_bases
GCATATCTTGCCATAGCCTTACTTTGTTTATTGCGTTACCGCCTGCATCCTTTGAGATGTTGTGGGCGCCGTTTAGTCAT
TCCTTAAGCAGGAGCTTGTC

Downstream 100 bases:

>100_bases
CGTCACACGCAGGAATCAAGTCTATAGATGCGGCATCGCGGACATAATCTGTCCGTTATGCCGGGCGGGCGGCGGCGCGC
TGCCCGCCAGCCACTGTGGA

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 519; Mature: 519

Protein sequence:

>519_residues
MELLMDPSIWVGLLTLVVLEIVLGIDNLVFIAILADKLPPKQRDKARLIGLSLALIMRLALLSIISWLVTLTKSLFTVWD
FTFSGRDLIMLLGGIFLLFKATTELHERLENREHDTGHGKGYASFWVVVTQIVILDAVFSLDAVITAVGMVNHLPVMMAA
VVIAMAVMLLASKPLTRFVNQHPTVVVLCLSFLLMIGLSLVAEGFGFHIPKGYLYAAIGFSIVIEVFNQIARRNFIRHQS
TLPLRARTADAILRLMGGKRQASMQHETDSPAAISVSEGAFAEEERYMINGVLTLASRSLRGIMTPRGEISWVDANLSVA
EIRQQLLSSPHSLFPVCRGELDEIIGIVRAKELLVALEEGADVAAIAASSPAIVVPETLDPINLLGVLRRARGSFVIVTN
EFGVVQGLVTPLDVLEAIAGEFPDADETPEIVADAEGWIVKGGTDLHALQQALEVDHLVNEEGDIATVAGLVIAANGHIP
RVGDVIDVPPLRITIVEANDYRVDLVRIVKEQPAHDEEE

Sequences:

>Translated_519_residues
MELLMDPSIWVGLLTLVVLEIVLGIDNLVFIAILADKLPPKQRDKARLIGLSLALIMRLALLSIISWLVTLTKSLFTVWD
FTFSGRDLIMLLGGIFLLFKATTELHERLENREHDTGHGKGYASFWVVVTQIVILDAVFSLDAVITAVGMVNHLPVMMAA
VVIAMAVMLLASKPLTRFVNQHPTVVVLCLSFLLMIGLSLVAEGFGFHIPKGYLYAAIGFSIVIEVFNQIARRNFIRHQS
TLPLRARTADAILRLMGGKRQASMQHETDSPAAISVSEGAFAEEERYMINGVLTLASRSLRGIMTPRGEISWVDANLSVA
EIRQQLLSSPHSLFPVCRGELDEIIGIVRAKELLVALEEGADVAAIAASSPAIVVPETLDPINLLGVLRRARGSFVIVTN
EFGVVQGLVTPLDVLEAIAGEFPDADETPEIVADAEGWIVKGGTDLHALQQALEVDHLVNEEGDIATVAGLVIAANGHIP
RVGDVIDVPPLRITIVEANDYRVDLVRIVKEQPAHDEEE
>Mature_519_residues
MELLMDPSIWVGLLTLVVLEIVLGIDNLVFIAILADKLPPKQRDKARLIGLSLALIMRLALLSIISWLVTLTKSLFTVWD
FTFSGRDLIMLLGGIFLLFKATTELHERLENREHDTGHGKGYASFWVVVTQIVILDAVFSLDAVITAVGMVNHLPVMMAA
VVIAMAVMLLASKPLTRFVNQHPTVVVLCLSFLLMIGLSLVAEGFGFHIPKGYLYAAIGFSIVIEVFNQIARRNFIRHQS
TLPLRARTADAILRLMGGKRQASMQHETDSPAAISVSEGAFAEEERYMINGVLTLASRSLRGIMTPRGEISWVDANLSVA
EIRQQLLSSPHSLFPVCRGELDEIIGIVRAKELLVALEEGADVAAIAASSPAIVVPETLDPINLLGVLRRARGSFVIVTN
EFGVVQGLVTPLDVLEAIAGEFPDADETPEIVADAEGWIVKGGTDLHALQQALEVDHLVNEEGDIATVAGLVIAANGHIP
RVGDVIDVPPLRITIVEANDYRVDLVRIVKEQPAHDEEE

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Escherichia coli, GI1788119, Length=519, Percent_Identity=90.7514450867052, Blast_Score=932, Evalue=0.0,
Organism=Escherichia coli, GI87082033, Length=519, Percent_Identity=50.0963391136802, Blast_Score=442, Evalue=1e-125,
Organism=Escherichia coli, GI1789197, Length=229, Percent_Identity=49.7816593886463, Blast_Score=206, Evalue=2e-54,
Organism=Escherichia coli, GI1790664, Length=241, Percent_Identity=26.9709543568465, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1786879, Length=226, Percent_Identity=32.3008849557522, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI145693175, Length=244, Percent_Identity=28.2786885245902, Blast_Score=84, Evalue=2e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR005496
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF03741 TerC [H]

EC number: NA

Molecular weight: Translated: 56524; Mature: 56524

Theoretical pI: Translated: 4.78; Mature: 4.78

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CCCCEECCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure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CCCCEECCCCCEEEEEECCCCHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]