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The map label for this gene is umuD [H]

Identifier: 29141368

GI number: 29141368

Start: 981317

End: 981736

Strand: Direct

Name: umuD [H]

Synonym: t0880

Alternate gene names: 29141368

Gene position: 981317-981736 (Clockwise)

Preceding gene: 29141367

Following gene: 29141369

Centisome position: 20.48

GC content: 50.0

Gene sequence:

>420_bases
ATGGAATTTTTCAGACCTACAGAGTTGCGCGAAATTATTCCTCTCCCATTTTTCAGTTACTTAGTGCCGTGTGGATTCCC
CAGCCCCGCGGCGGACTATATTGAGCAGCGTATCGATCTTAATGAGTTGCTCGTTTCTCATCCCAGCTCAACATATTTTG
TCAAAGCAACGGGGGATTCAATGATTGAAGCAGGCATCAGCGACGGTGACCTGCTGGTGGTGGATAGCTCACGGAACGCT
GACCACGGTGACATTGTAATTGCGGCAATTGAAGGAGAGTTCACCGTAAAGCGGTTGCAGTTGCGTCCGACAGTGCAGTT
AATCCCCATGAACGGCGCCTATCGACCCATACCTGTCGGCAGTGAAGACACGCTCGACATATTCGGGGTGGTGACCTTTA
TCATTAAAGCGGTCAGTTGA

Upstream 100 bases:

>100_bases
CGAAGCGACGAAGATTTAAACAGTCGTAGCGACTCCGGTATCTTGCGCGCATGTTCAAATAACACTACTGTATATAAAAA
CAGTATTCGAGGTATGGATT

Downstream 100 bases:

>100_bases
TTATGTTCGCGCTCTGCGATGTTAATAGCTTTTACGCCTCCTGCGAAACGGTCTTTCGTCCTGATTTATGTGGCCGACCG
GTGGTGGTGTTATCAAACAA

Product: DNA polymerase V subunit UmuD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 139; Mature: 139

Protein sequence:

>139_residues
MEFFRPTELREIIPLPFFSYLVPCGFPSPAADYIEQRIDLNELLVSHPSSTYFVKATGDSMIEAGISDGDLLVVDSSRNA
DHGDIVIAAIEGEFTVKRLQLRPTVQLIPMNGAYRPIPVGSEDTLDIFGVVTFIIKAVS

Sequences:

>Translated_139_residues
MEFFRPTELREIIPLPFFSYLVPCGFPSPAADYIEQRIDLNELLVSHPSSTYFVKATGDSMIEAGISDGDLLVVDSSRNA
DHGDIVIAAIEGEFTVKRLQLRPTVQLIPMNGAYRPIPVGSEDTLDIFGVVTFIIKAVS
>Mature_139_residues
MEFFRPTELREIIPLPFFSYLVPCGFPSPAADYIEQRIDLNELLVSHPSSTYFVKATGDSMIEAGISDGDLLVVDSSRNA
DHGDIVIAAIEGEFTVKRLQLRPTVQLIPMNGAYRPIPVGSEDTLDIFGVVTFIIKAVS

Specific function: Involved in UV protection and mutation. Essential for induced (or SOS) mutagenesis. May modify the DNA replication machinery to allow bypass synthesis across a damaged template [H]

COG id: COG1974

COG function: function code KT; SOS-response transcriptional repressors (RecA-mediated autopeptidases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase S24 family [H]

Homologues:

Organism=Escherichia coli, GI1787431, Length=138, Percent_Identity=72.463768115942, Blast_Score=218, Evalue=2e-58,
Organism=Escherichia coli, GI1790476, Length=117, Percent_Identity=33.3333333333333, Blast_Score=64, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006197
- InterPro:   IPR019759
- InterPro:   IPR015927
- InterPro:   IPR011056 [H]

Pfam domain/function: PF00717 Peptidase_S24 [H]

EC number: 3.4.21.-

Molecular weight: Translated: 15303; Mature: 15303

Theoretical pI: Translated: 4.25; Mature: 4.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFFRPTELREIIPLPFFSYLVPCGFPSPAADYIEQRIDLNELLVSHPSSTYFVKATGDS
CCCCCCCCHHHHCCCCHHHHHHCCCCCCCHHHHHHHHCCHHHHHHCCCCCEEEEEECCCC
MIEAGISDGDLLVVDSSRNADHGDIVIAAIEGEFTVKRLQLRPTVQLIPMNGAYRPIPVG
CEECCCCCCCEEEEECCCCCCCCCEEEEEECCCEEEEEEEECCCEEEEECCCCCCCCCCC
SEDTLDIFGVVTFIIKAVS
CCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MEFFRPTELREIIPLPFFSYLVPCGFPSPAADYIEQRIDLNELLVSHPSSTYFVKATGDS
CCCCCCCCHHHHCCCCHHHHHHCCCCCCCHHHHHHHHCCHHHHHHCCCCCEEEEEECCCC
MIEAGISDGDLLVVDSSRNADHGDIVIAAIEGEFTVKRLQLRPTVQLIPMNGAYRPIPVG
CEECCCCCCCEEEEECCCCCCCCCEEEEEECCCEEEEEEEECCCEEEEECCCCCCCCCCC
SEDTLDIFGVVTFIIKAVS
CCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2144275; 2203737; 11677609; 1910151 [H]