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The map label for this gene is cbiL [H]

Identifier: 29141344

GI number: 29141344

Start: 942781

End: 943494

Strand: Direct

Name: cbiL [H]

Synonym: t0850

Alternate gene names: 29141344

Gene position: 942781-943494 (Clockwise)

Preceding gene: 29141343

Following gene: 29141345

Centisome position: 19.67

GC content: 57.84

Gene sequence:

>714_bases
ATGAACGGTAAATTATACGCATTAAGTACCGGGCCAGGCGCGCCCGACCTGATAACCGTCCGCGCAGCGCGGATTCTTGG
CTCGCTGGACATTCTGTATGCGCCCGCCGGTCGTAAGGGGGGCGATAGTCTGGCGTTGTCGATTGTGCGCGACTATCTCG
GCGAGCAGACGGAAGTACGTTGTTGCCATTTCCCTATGAGCGCTGACGGCGCCGAGAAAGAAGCGGTCTGGAACGAGGTT
GCCGCCGCGCTTACCGCAGAGGTGGAAGCGGGTAAACAGGTCGGTTTTATTACCCTGGGCGATGCGATGCTATTCAGTAC
CTGGATTTTTTTACTCCAGAGAATCGGCTGCCCGGAGTGGCTGGAGATTGTCCCCGGCGTCACGTCCTTCGCCGCGATAG
CCGCCCGCGCGAAAATGCCGCTCGCCATAGAACGGCAATCGCTGGCGGTTATTTCTTGTACCGCGCCGGAAGCGGAAATA
GCCCAGGCGCTACAACAGCATGATAGCCTGGTGTTGATGAAAGTGTATGGCCGATTCGCCCGTATTAAAGCGTTGCTGGC
GCAGGCTGGCCTGCTGGAATGCGCCTTAATGATGTCCGAGGCCACGCTGCCCGGCGAGCAGTGCTGGCGCCACCTCCACG
AGGTCAACGATGATCGAGCGTTGCCCTATTTTTCGACCATTCTGGTCAATAAACAGTGGGAGTATGCAGAATGA

Upstream 100 bases:

>100_bases
CGACGCCGTGGCTGAGCGGGCTGGGAGAAAACCCGGCTATCCGGGCGATGTTTGTCGCGCATTTGCACCAGGCGCTGAAC
ATGGCGGTAGAGGAGGCGGC

Downstream 100 bases:

>100_bases
AACTTGAACAGCAGCTTAGACAGTTGTCTTTCAGTGGACTGGCTGCAGCGCTATTGCTGATGGTTGTCCCGCAACAGGCG
TTTGCGATGCATATCATGGA

Product: cobalt-precorrin-2 C(20)-methyltransferase

Products: NA

Alternate protein names: S-adenosyl-L-methionine--cobalt-precorrin-2 methyltransferase [H]

Number of amino acids: Translated: 237; Mature: 237

Protein sequence:

>237_residues
MNGKLYALSTGPGAPDLITVRAARILGSLDILYAPAGRKGGDSLALSIVRDYLGEQTEVRCCHFPMSADGAEKEAVWNEV
AAALTAEVEAGKQVGFITLGDAMLFSTWIFLLQRIGCPEWLEIVPGVTSFAAIAARAKMPLAIERQSLAVISCTAPEAEI
AQALQQHDSLVLMKVYGRFARIKALLAQAGLLECALMMSEATLPGEQCWRHLHEVNDDRALPYFSTILVNKQWEYAE

Sequences:

>Translated_237_residues
MNGKLYALSTGPGAPDLITVRAARILGSLDILYAPAGRKGGDSLALSIVRDYLGEQTEVRCCHFPMSADGAEKEAVWNEV
AAALTAEVEAGKQVGFITLGDAMLFSTWIFLLQRIGCPEWLEIVPGVTSFAAIAARAKMPLAIERQSLAVISCTAPEAEI
AQALQQHDSLVLMKVYGRFARIKALLAQAGLLECALMMSEATLPGEQCWRHLHEVNDDRALPYFSTILVNKQWEYAE
>Mature_237_residues
MNGKLYALSTGPGAPDLITVRAARILGSLDILYAPAGRKGGDSLALSIVRDYLGEQTEVRCCHFPMSADGAEKEAVWNEV
AAALTAEVEAGKQVGFITLGDAMLFSTWIFLLQRIGCPEWLEIVPGVTSFAAIAARAKMPLAIERQSLAVISCTAPEAEI
AQALQQHDSLVLMKVYGRFARIKALLAQAGLLECALMMSEATLPGEQCWRHLHEVNDDRALPYFSTILVNKQWEYAE

Specific function: Methylates cobalt-precorrin-2 at the C-20 position to produce cobalt-precorrin-3A in the anaerobic cobalamin biosynthesis pathway [H]

COG id: COG2243

COG function: function code H; Precorrin-2 methylase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the precorrin methyltransferase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000878
- InterPro:   IPR014777
- InterPro:   IPR012382
- InterPro:   IPR006364
- InterPro:   IPR003043 [H]

Pfam domain/function: PF00590 TP_methylase [H]

EC number: =2.1.1.151 [H]

Molecular weight: Translated: 25780; Mature: 25780

Theoretical pI: Translated: 4.93; Mature: 4.93

Prosite motif: PS00839 SUMT_1 ; PS00840 SUMT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNGKLYALSTGPGAPDLITVRAARILGSLDILYAPAGRKGGDSLALSIVRDYLGEQTEVR
CCCEEEEEECCCCCCCHHHHHHHHHHCCHHEEECCCCCCCCHHHHHHHHHHHHCCCCCEE
CCHFPMSADGAEKEAVWNEVAAALTAEVEAGKQVGFITLGDAMLFSTWIFLLQRIGCPEW
EEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECHHHHHHHHHHHHHHCCCHHH
LEIVPGVTSFAAIAARAKMPLAIERQSLAVISCTAPEAEIAQALQQHDSLVLMKVYGRFA
HHHHCCHHHHHHHHHHCCCCEEEECCCEEEEEECCCHHHHHHHHHHCCCEEHHHHHHHHH
RIKALLAQAGLLECALMMSEATLPGEQCWRHLHEVNDDRALPYFSTILVNKQWEYAE
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHEEECCCCCCC
>Mature Secondary Structure
MNGKLYALSTGPGAPDLITVRAARILGSLDILYAPAGRKGGDSLALSIVRDYLGEQTEVR
CCCEEEEEECCCCCCCHHHHHHHHHHCCHHEEECCCCCCCCHHHHHHHHHHHHCCCCCEE
CCHFPMSADGAEKEAVWNEVAAALTAEVEAGKQVGFITLGDAMLFSTWIFLLQRIGCPEW
EEECCCCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEEEECHHHHHHHHHHHHHHCCCHHH
LEIVPGVTSFAAIAARAKMPLAIERQSLAVISCTAPEAEIAQALQQHDSLVLMKVYGRFA
HHHHCCHHHHHHHHHHCCCCEEEECCCEEEEEECCCHHHHHHHHHHCCCEEHHHHHHHHH
RIKALLAQAGLLECALMMSEATLPGEQCWRHLHEVNDDRALPYFSTILVNKQWEYAE
HHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCHHHHHEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8501034; 11677609 [H]